Expression of target genes of nuclear factor E2-related factor 2 in the liver of dairy cows in the transition period and at different stages of lactation

Journal of Dairy Science

Volumn 96, Issue 2, 2013, Pages 1038-1043

  Gessner, D K ^a   Schlegel, G ^a   Keller, J ^a   Schwarz, F J ^b   Ringseis, R ^a   Eder, K ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Dairy cow; Inflammation; Liver; Nuclear factor E2 related factor 2 (Nrf2); Transition period

Indexed keywords

ACUTE PHASE PROTEIN; C REACTIVE PROTEIN; HAPTOGLOBIN; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; BIOSYNTHESIS; CATTLE; FEMALE; GENE EXPRESSION REGULATION; GENETICS; LACTATION; LIVER; METABOLISM; PERINATAL PERIOD; PHYSIOLOGY; PUERPERIUM;

ACUTE-PHASE PROTEINS; ANIMALS; C-REACTIVE PROTEIN; CATTLE; FEMALE; GENE EXPRESSION REGULATION; HAPTOGLOBINS; LACTATION; LIVER; NF-E2-RELATED FACTOR 2; PERIPARTUM PERIOD; POSTPARTUM PERIOD; TUMOR NECROSIS FACTOR-ALPHA;

BOS;

EID: 84872681542     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2012-5967     Document Type: Article

References (25)

1. Baird L., Dinkova-Kostova A.T. The cytoprotective role of the Keap1-Nrf2 pathway. Arch. Toxicol 2011, 85:241-272.
2. Bertoni G., Trevisi E., Han X., Bionaz M. Effects of inflammatory conditions on liver activity in puerperium period and consequences for performance in dairy cows. J. Dairy Sci 2008, 91:3300-3310.
3. Bionaz M., Trevisi E., Calamari L., Librandi F., Ferrari A., Bertoni G. Plasma paraoxonase, health, inflammatory conditions, and liver function in transition dairy cows. J. Dairy Sci 2007, 90:1740-1750.
4. Bradford B.J., Mamedova L.K., Minton J.E., Drouillard J.S., Johnson B.J. Daily injection of tumor necrosis factor-α increases hepatic triglycerides and alters transcript abundance of metabolic genes in lactating dairy cattle. J. Nutr 2009, 139:1451-1456.
5. Drackley J.K. Biology of dairy cows during the transition period: The final frontier?. J. Dairy Sci 1999, 82:2259-2273.
6. Itoh K., Chiba T., Takahashi S., Ishii T., Igarashi K., Katoh Y., Oyake T., Hayashi N., Satoh K., Hatayama I., Yamamoto M., Nabeshima Y. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem. Biophys. Res. Commun 1997, 236:313-322.
7. Kaspar J.W., Niture S.K., Jaiswal A.K. Nrf2:INrf2 (Keap1) signaling in oxidative stress. Free Radic. Biol. Med 2009, 47:1304-1309.
8. Kim J., Cha Y.-N., Surh Y.-J. A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders. Mutat. Res 2010, 690:12-23.
9. Köhle C., Bock K.W. Coordinate regulation of phase I and II xenobiotic metabolism by the Ah receptor and Nrf2. Biochem. Pharmacol 2007, 73:1853-1862.
10. Kuhla B., Albrecht D., Kuhla S., Metges C.C. Proteome analysis of fatty liver in feed-deprived dairy cows reveals interaction of fuel sensing, calcium, fatty acid, and glycogen metabolism. Physiol. Genomics 2009, 37:88-98.
11. Loor J.J., Dann H.M., Everts R.E., Oliveira R., Green C.A., Guretzky N.A., Rodriguez-Zas S.L., Lewin H.A., Drackley J.K. Temporal gene expression profiling of liver from periparturient dairy cows reveals complex adaptive mechanisms in hepatic function. Physiol. Genomics 2005, 23:217-226.
12. Loor J.J., Everts R.E., Bionaz M., Dann H.M., Morin D.E., Oliveira R., Rodriguez-Zas S.L., Drackley J.K., Lewin H.A. Nutrition-induced ketosis alters metabolic and signaling gene networks in liver of periparturient dairy cows. Physiol. Genomics 2007, 32:105-116.
13. McCabe M., Waters S., Morris D., Kenny D., Lynn D., Creevey C. RNA-seq analysis of differential gene expression in liver from lactating dairy cows divergent in negative energy balance. BMC Genomics 2012, 13:193.
14. McCarthy S.D., Waters S.M., Kenny D.A., Diskin M.G., Fitzpatrick R., Patton J., Wathes D.C., Morris D.G. Negative energy balance and hepatic gene expression patterns in high-yielding dairy cows during the early postpartum period: A global approach. Physiol. Genomics 2010, 42A:188-199.
15. Morris D.G., Waters S.M., McCarthy S.D., Patton J., Earley B., Fitzpatrick R., Murphy J.J., Diskin M.G., Kenny D.A., Brass A., Wathes D.C. Pleiotropic effects of negative energy balance in the post-partum dairy cow on splenic gene expression: Repercussions for innate and adaptive immunity. Physiol. Genomics 2009, 39:28-37.
16. Nair S., Doh S.T., Chan J.Y., Kong A.-N., Cai L. Regulatory potential for concerted modulation of Nrf2- and Nfkb1-mediated gene expression in inflammation and carcinogenesis. Br. J. Cancer 2008, 99:2070-2082.
17. Rahman I., Biswas S.K., Kirkham P.A. Regulation of inflammation and redox signaling by dietary polyphenols. Biochem. Pharmacol 2006, 72:1439-1452.
18. Schlegel G., Keller J., Hirche F., Geißler S., Schwarz F.J., Ringseis R., Stangl G.I., Eder K. Expression of genes involved in hepatic carnitine synthesis and uptake in dairy cows in the transition period and at different stages of lactation. BMC Vet. Res 2012, 8:28.
19. Schlegel G., Ringseis R., Keller J., Schwarz F.J., Eder K. Changes in the expression of hepatic genes involved in cholesterol homeostasis in dairy cows in the transition period and at different stages of lactation. J. Dairy Sci 2012, 95:3826-3836.
20. Sordillo L.M., Contreras G.A., Aitken S.L. Metabolic factors affecting the inflammatory response of periparturient dairy cows. Anim. Health Res. Rev 2009, 10:53-63.
21. Trevisi E., Amadori M., Cogrossi S., Razzuoli E., Bertoni G. Metabolic stress and inflammatory response in high-yielding, periparturient dairy cows. Res. Vet. Sci 2012, 93:695-704.
22. Trevisi E., Bertoni G. Attenuation with acetylsalicylate treatments of inflammatory conditions in periparturient dairy cows. Aspirin and Health Research Progress 2008, 22-37. Nova Science Publishers, New York, NY. P.I. Quinn (Ed.).
23. Trevisi E., Zecconi A., Bertoni G., Piccinini R. Blood and milk immune and inflammatory profiles in periparturient dairy cows showing a different liver activity index. J. Dairy Res 2010, 77:310-317.
24. Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002, 3. RESEARCH0034.
25. Zebeli Q., Metzler-Zebeli B.U. Interplay between rumen digestive disorders and diet-induced inflammation in dairy cattle. Res. Vet. Sci 2012, 93:1099-1108.