Sex-related differences in carotid plaque features and inflammation

Journal of Vascular Surgery

Volumn 57, Issue 2, 2013, Pages 338-344

  Sangiorgi, Giuseppe ^a   Roversi, Sara ^b   Biondi Zoccai, Giuseppe ^c   Modena, Maria Grazia ^b   Servadei, Francesca ^a   Ippoliti, Arnaldo ^a   Mauriello, Alessandro ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHYPERTENSIVE AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INSULIN; ORAL ANTIDIABETIC AGENT;

ADULT; AGED; ANTIHYPERTENSIVE THERAPY; ARTICLE; ASYMPTOMATIC DISEASE; CAROTID ARTERY OBSTRUCTION; CAROTID ATHEROSCLEROSIS; CAROTID ENDARTERECTOMY; CORONARY ARTERY ATHEROSCLEROSIS; DIABETES MELLITUS; DISEASE SEVERITY; FEMALE; FOAM CELL; FRAMINGHAM RISK SCORE; HISTOPATHOLOGY; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; INSULIN TREATMENT; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; MEASUREMENT; PREVALENCE; PRIORITY JOURNAL; SEX DIFFERENCE; SMOKING;

AGED; ASYMPTOMATIC DISEASES; CAROTID ARTERIES; CAROTID STENOSIS; CHI-SQUARE DISTRIBUTION; ENDARTERECTOMY, CAROTID; FEMALE; FOAM CELLS; HEMORRHAGE; HUMANS; HYPERCHOLESTEROLEMIA; HYPERTENSION; INFLAMMATION; LINEAR MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NECROSIS; PLAQUE, ATHEROSCLEROTIC; PREVALENCE; RISK ASSESSMENT; RISK FACTORS; ROME; SEVERITY OF ILLNESS INDEX; SEX FACTORS; SMOKING; THROMBOSIS;

EID: 84872680149     PISSN: 07415214     EISSN: 10976809     Source Type: Journal    
DOI: 10.1016/j.jvs.2012.07.052     Document Type: Article

References (40)

1. V.L. Roger, A.S. Go, D.M. Lloyd-Jones, R.J. Adams, J.D. Berry, and T.M. Brown Heart disease and stroke statistics-2011 update: a report from the American Heart Association Circulation 123 2011 e18 e209
2. D. Inzitari, M. Eliasziw, P. Gates, B.L. Sharpe, R.K. Chan, and H.E. Meldrum The causes and risk of stroke in patients with asymptomatic internal-carotid-artery stenosis North American Symptomatic Carotid Endarterectomy Trial Collaborators N Engl J Med 342 2000 1693 1700
3. P.M. Rothwell, R. Gibson, and C.P. Warlow Interrelation between plaque surface morphology and degree of stenosis on carotid angiograms and the risk of ischemic stroke in patients with symptomatic carotid stenosis On behalf of the European Carotid Surgery Trialists' Collaborative Group Stroke 31 2000 615 621
4. J.W. Norris, and C.Z. Zhu Silent stroke and carotid stenosis Stroke 23 1992 483 485
5. J. Golledge, R.M. Greenhalgh, and A.H. Davies The symptomatic carotid plaque Stroke 31 2000 774 781
6. North American Symptomatic Carotid Endarterectomy Trial Collaborators Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis N Engl J Med 325 1991 445 453
7. [No authors listed] Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European carotid surgery trial (ECST) Lancet 351 1998 1379 1387
8. R.E. Petrea, A.S. Beiser, S. Seshadri, M. Kelly-Hayes, C.S. Kase, and P.A. Wolf Gender differences in stroke incidence and poststroke disability in the Framingham heart study Stroke 40 2009 1032 1037
9. S. Ebrahim, O. Papacosta, P. Whincup, G. Wannamethee, M. Walker, and A.N. Nicolaides Carotid plaque, intima media thickness, cardiovascular risk factors, and prevalent cardiovascular disease in men and women: The British regional heart study Stroke 30 1999 841 850
10. O. Joakimsen, K.H. Bonaa, E. Stensland-Bugge, and B.K. Jacobsen Age and sex differences in the distribution and ultrasound morphology of carotid atherosclerosis: The Tromsø study Arterioscler Thromb Vasc Biol 19 1999 3007 3013
11. S.H. Han, J.H. Bae, D.R. Holmes Jr, R.J. Lennon, E. Eeckhout, and G.W. Barsness Sex differences in atheroma burden and endothelial function in patients with early coronary atherosclerosis Eur Heart J 29 2008 1359 1369
12. R. Virmani, F.D. Kolodgie, A.P. Burke, A. Farb, and S.M. Schwartz Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions Arterioscler Thromb Vasc Biol 20 2000 1262 1275
13. L. Nathan, S. Pervin, R. Singh, M. Rosenfeld, and G. Chaudhuri Estradiol inhibits leukocyte adhesion and transendothelial migration in rabbits in vivo: possible mechanisms for gender differences in atherosclerosis Circ Res 85 1999 377 385
14. R.J. Frink Gender gap, inflammation and acute coronary disease: are women resistant to atheroma growth? Observations at autopsy J Invasive Cardiol 21 2009 270 277
15. D. Xing, S. Nozell, Y.F. Chen, F. Hage, and S. Oparil Estrogen and mechanisms of vascular protection Arterioscler Thromb Vasc Biol 29 2009 289 295
16. L.G. Spagnoli, A. Mauriello, G. Sangiorgi, S. Fratoni, E. Bonanno, and R.S. Schwartz Extracranial thrombotically active carotid plaque as a risk factor for ischemic stroke JAMA 292 2004 1845 1852
17. A. Mauriello, F. Servadei, G. Sangiorgi, L. Anemona, E. Giacobbi, and D. Liotti Asymptomatic carotid plaque rupture with unexpected thrombosis over a non-canonical vulnerable lesion Atherosclerosis 218 2011 356 362
18. F.B. Hu, F. Grodstein, C.H. Hennekens, G.A. Colditz, M. Johnson, and J.E. Manson Age at natural menopause and risk of cardiovascular disease Arch Intern Med 159 1999 1061 1066
19. I. Kardys, R. Vliegenthart, M. Oudkerk, A. Hofman, and J.C. Witteman The female advantage in cardiovascular disease: do vascular beds contribute equally? Am J Epidemiol 166 2007 403 412
20. N. Agrinier, M. Cournot, J. Dallongeville, D. Arveiler, P. Ducimetière, and J.B. Ruidavets Menopause and modifiable coronary heart disease risk factors: a population based study Maturitas 65 2010 237 243
21. K. Saltiki, and M. Alevizaki Coronary heart disease in postmenopausal women; the role of endogenous estrogens and their receptors Hormones (Athens) 6 2007 9 24
22. A.P. Burke, A. Farb, G. Malcom, and R. Virmani Effect of menopause on plaque morphologic characteristics in coronary atherosclerosis Am Heart J 141 2 Suppl 2001 S58 S62
23. F. Iemolo, A. Martiniuk, D.A. Steinman, and J.D. Spence Sex differences in carotid plaque and stenosis Stroke 35 2004 477 481
24. S.J. Nicholls, K. Wolski, I. Sipahi, P. Schoenhagen, T. Crowe, and S.R. Kapadia Rate of progression of coronary atherosclerotic plaque in women J Am Coll Cardiol 49 2007 1546 1551
25. M.E. Mendelsohn, and R.H. Karas HRT and the young at heart N Engl J Med 356 2007 2639 2641
26. J.E. Manson, J. Hsia, K.C. Johnson, J.E. Rossouw, A.R. Assaf, and N.L. Lasser Estrogen plus progestin and the risk of coronary heart disease N Engl J Med 349 2003 523 534
27. R. Marfella, C. Di Filippo, M. Portoghese, F. Ferraraccio, B. Crescenzi, and M. Siniscalchi Proteasome activity as a target of hormone replacement therapy-dependent plaque stabilization in postmenopausal women Hypertension 51 2008 1135 1141
28. M.G. Ionita, P. van den Borne, L.M. Catanzariti, F.L. Moll, J.P. de Vries, and G. Pasterkamp High neutrophil numbers in human carotid atherosclerotic plaques are associated with characteristics of rupture-prone lesions Arterioscler Thromb Vasc Biol 30 2010 1842 1848
29. W.E. Hellings, G. Pasterkamp, B.A. Verhoeven, D.P. De Kleijn, J.P. De Vries, and K.A. Seldenrijk Gender-associated differences in plaque phenotype of patients undergoing carotid endarterectomy J Vasc Surg 45 2007 289 296 discussion: 296-7
30. H. Ota, M.J. Reeves, D.C. Zhu, A. Majid, A. Collar, and C. Yuan Sex differences in patients with asymptomatic carotid atherosclerotic plaque In vivo 3.0-T magnetic resonance study Stroke 41 2010 1630 1635
31. L.M. Buja, and J.T. Willerson Role of inflammation in coronary plaque disruption Circulation 89 1994 503 505
32. S.Z. Rittersma, A.C. van der Wal, K.T. Koch, J.J. Piek, J.P. Henriques, and K.J. Mulder Plaque instability frequently occurs days or weeks before occlusive coronary thrombosis: a pathological thrombectomy study in primary percutaneous coronary intervention Circulation 111 2005 1160 1165
33. M. Sitzer, W. Müller, M. Siebler, W. Hort, H.W. Kniemeyer, and L. Jäncke Plaque ulceration and lumen thrombus are the main sources of cerebral microemboli in high-grade internal carotid artery stenosis Stroke 26 1995 1231 1233
34. J.A. Berliner, M. Navab, A.M. Fogelman, J.S. Frank, L.L. Demer, and P.A. Edwards Atherosclerosis: basic mechanisms Oxidation, inflammation, and genetics Circulation 91 1995 2488 2496
35. P. Libby Coronary artery injury and the biology of atherosclerosis: inflammation, thrombosis, and stabilization Am J Cardiol 86 2000 3J 8J discussion: 8J-9J
36. A.C. van der Wal, and A.E. Becker Atherosclerotic plaque rupture-pathologic basis of plaque stability and instability Cardiovasc Res 41 1999 334 344
37. A.K. Jacobs Women, ischemic heart disease, revascularization, and the gender gap: what are we missing? J Am Coll Cardiol 47 3 Suppl 2006 S63 S65
38. B.D. MacNeill, I.K. Jang, B.E. Bouma, N. Iftimia, M. Takano, and H. Yabushita Focal and multi-focal plaque macrophage distributions in patients with acute and stable presentations of coronary artery disease J Am Coll Cardiol 44 2004 972 979
39. A.C. van der Wal, A.E. Becker, C.M. van der Loos, and P.K. Das Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology Circulation 89 1994 36 44
40. A.G. den Hartog, A. Algra, F.L. Moll, and G.J. de Borst Mechanisms of gender-related outcome differences after carotid endarterectomy J Vasc Surg 52 2010 1062 1071