Proteasome activity as a target of hormone replacement therapy-dependent plaque stabilization in postmenopausal women

Hypertension

Volumn 51, Issue 4 PART 2 SUPPL., 2008, Pages 1135-1141

  Marfella, Raffaele ^a,d   Filippo, Clara Di ^a   Portoghese, Michele ^b   Ferraraccio, Franca ^a   Crescenzi, Basilio ^c   Siniscalchi, Mario ^a   Barbieri, Michelangela ^a   Bologna, Carolina ^a   Rizzo, Maria Rosaria ^a   Rossi, Francesco ^a   D'Amico, Michele ^a   Paolisso, Giuseppe ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b Sassari Hospital   (Italy)

^c Hospital V Monaldi   (Italy)

^d NONE   (Italy)

Author keywords

Atherosclerotic plaque; Hormone replacement therapy; Inflammation; Ubiquitin proteasome activity

Indexed keywords

3 NITROTYROSINE; ACETYLSALICYLIC ACID; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANTIDIABETIC AGENT; CALCIUM CHANNEL BLOCKING AGENT; COLLAGEN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; ESTRADIOL; GELATINASE B; GESTAGEN; HLA DR ANTIGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; MEDROXYPROGESTERONE ACETATE; PROTEASOME; TUMOR NECROSIS FACTOR ALPHA; UBIQUITIN;

ADULT; AGED; ARTICLE; ATHEROSCLEROTIC PLAQUE; CAROTID ARTERY OBSTRUCTION; CAROTID ENDARTERECTOMY; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DIASTOLIC BLOOD PRESSURE; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HORMONE SUBSTITUTION; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MAJOR CLINICAL STUDY; OXIDATIVE STRESS; POSTMENOPAUSE; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE; T LYMPHOCYTE;

AGED; CAROTID ARTERIES; CAROTID ARTERY DISEASES; DOWN-REGULATION; ENDARTERECTOMY, CAROTID; ESTROGEN REPLACEMENT THERAPY; FEMALE; HUMANS; MIDDLE AGED; NF-KAPPA B; OXIDATIVE STRESS; POSTMENOPAUSE; PREOPERATIVE CARE; PROTEASOME ENDOPEPTIDASE COMPLEX; SUPEROXIDES; TYROSINE; UBIQUITIN; VASCULITIS;

EID: 40849118447     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.107.105239     Document Type: Article

References (33)

1. American Heart Association. Heart Disease and Stroke Statistics: 2003 Update. Dallas, TX: American Heart Association; 2002.
2. Oparil S. Arthur C. Corcoran memorial lecture: hormone and vasoprotection. Hypertension. 1999;33:170-176.
3. Grodstein F, Manson JE, Colditz GA, Willett WC, Speizer FE, Stampfer MJ. A prospective, observational study of postmenopausal hormone therapy and primary prevention of cardiovascular disease. Ann Intern Med. 2000;133:933-941.
4. Sullivan JM, Vander Zwaag R, Lemp GF, Hughes JP, Maddock V, Kroetz FW. Postmenopausal estrogen use and coronary atherosclerosis. Ann Intern Med. 1998;108:358-363.
5. McFarland KF, Boniface ME, Hornung CA, Earnhardt W, Humphries JO. Risk factors and noncontraceptive estrogen use in women with and without coronary disease. Am Heart J. 1989;6:1209-1214.
6. Mendelsohn ME, Karas RH. The protective effects of estrogen on the cardiovascular system. N Engl J Med. 1999;340:1801-1811.
7. Miller AP, Chen YF, Xing D, Feng W, Oparil S. Hormone replacement therapy and inflammation: interactions in cardiovascular disease. Hypertension. 2003;42:657-663.
8. Skoog T, Dichtl W, Boquist S, Skoglund-Andersson C, Karpe F, Tang R, Bond MG, de Faire U, Nilsson J, Eriksson P, Hamsten A. Plasma tumour necrosis factor-alpha and early carotid atherosclerosis in healthy middle-aged men. Eur Heart J. 2002;23:376-383.
9. Herrmann J, Ciechanover A, Lerman LO, Lerman A. The ubiquitin-proteasome system in cardiovascular diseases-a hypothesis extended. Cardiovasc Res. 2004;61:11-21.
10. Kikuchi, Furukawa Y, Kubo N. Induction of ubiquitin-conjugating enzyme by aggregated low density lipoprotein in human macrophages and its implications for atherosclerosis. Arterioscler Thromb Vasc Biol. 2000;20:128-134.
11. Wang P, Zweier JL. Measurement of nitric oxide and peroxynitrite generation in the postischemic heart. Evidence for peroxynitrite-mediated reperfusion injury. J Biol Chem. 1996;271:29223-29230.
12. Young B, Moore WS, Robertson JT, Toole JF, Ernst CB, Cohen SN, Broderick JP, Dempsey RJ, Hosking JD. An analysis of perioperative surgical mortality and morbility in the Asymptomatic Carotid Atherosclerosis Study. Stroke. 1996;27:2216-2224.
13. Ohlsson BG, Englund MCO, Karlsson ALK, Knutsen E, Erixon C, Skribeck H, Liu Y, Bondjers G, Wiklund O. Oxidized low density lipoprotein inhibits lipopolysaccharide-induced binding of nuclear factor-kB to DNA and the subsequent expression of tumor necrosis factor-α and interleukin-1β in macrophages. J Clin Invest. 1996;98:78-89.
14. de Vries HE, Buchner B, van Berkel TJ, Kuiper J. Specific interaction of oxidized low-density lipoprotein with macrophage-derived foam cells isolated from rabbit atherosclerotic lesions. Arterioscler Thromb Vasc Biol. 1999;19:638-645.
15. Marfella R, Siniscalchi M, Portoghese M, Di Filippo C, Ferraraccio F, Schiattarella C, Crescenzi B, Sangiuolo P, Ferraro G, Siciliano S, Cinone F, Mazzarella G, Martis S, Verza M, Coppola L, Rossi F, D'Amico M, Paolisso G. Morning blood pressure surge as a destabilizing factor of atherosclerotic plaque: role of ubiquitin-proteasome activity. Hypertension. 2007;49:784-791.
16. Marfella R, D'Amico M, Esposito K, Baldi A, Di Filippo C, Siniscalchi M, Sasso FC, Portoghese M, Cirillo F, Cacciapuoti F, Carbonara O, Crescenzi B, Baldi F, Ceriello A, Nicoletti GF, D'Andrea F, Verza M, Coppola L, Rossi F, Giugliano D. The ubiquitin-proteasome system and inflammatory activity in diabetic atherosclerotic plaques: effects of rosiglitazone treatment. Diabetes. 2006;55:622-632.
17. Marfella R, D'Amico M, Di Filippo C, Baldi A, Siniscalchi M, Sasso FC, Portoghese M, Carbonara O, Crescenzi B, Sangiuolo P, Nicoletti GF, Rossiello R, Ferraraccio F, Cacciapuoti F, Verza M, Coppola L, Rossi F, Paolisso G. Increased activity of the ubiquitin-proteasome system in patients with symptomatic carotid disease is associated with enhanced inflammation and may destabilize the atherosclerotic plaque: effects of rosiglitazone treatment. J Am Coll Cardiol. 2006;47:2444-2455.
18. Li G, Chen YF, Greene GL, Oparil S, Thompson JA. Estrogen inhibits vascular smooth muscle cell-dependent adventitial fibroblast migration in vitro. Circulation. 1999;100:1639-1645.
19. Li G, Chen YF, Kelpke SS, Oparil S, Thompson JA. Estrogen attenuates integrin-β 3-dependent adventitial fibroblast migration after inhibition of osteopontin production in vascular smooth muscle cells. Circulation. 2000;101:2949-2955.
20. Burke AP, Farb A, Malcom G, Virmani R. Effect of menopause on plaque morphologic characteristics in coronary atherosclerosis. Am Heart J. 2001;141(2 suppl):S58-S62.
21. Xing D, Miller A, Smith M, Novak L, Chen YF, Oparil S. Ovarian hormones modulate the inflammatory response to vascular injury. Am J Hypertens. 2003;16:259A.
22. Siebenlist U, Franzoso G, Brown K. Structure, regulation and function of NF-kappa B. Annu Rev Cell Biol. 1994;10:405-455.
23. Herrmann J, Gulati R, Napoli C, Woodrum JE, Lerman LO, Rodriguez-Porcel M, Sica V, Simari RD, Ciechanover A, Lerman A. Oxidative stress-related increase in ubiquitination in early coronary atherosclerosis. FASEB J. 2003;17:1730-1732.
24. Tedgui A, Mallat Z. Cytokines in atherosclerosis. Pathogenic and regulatory pathways. Physiol Rev. 2006;86:515-581.
25. Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med. 1999;340:115-126.
26. Xu J, Wu Y, Song P, Zhang M, Wang S, Zou MH. Proteasome-dependent degradation of guanosine 5′-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus. Circulation. 2007;116:944-953.
27. Sack MN, Rader DJ, Cannon RO. Oestrogen and inhibition of oxidation of low-density lipoproteins in postmenopausal women. Lancet. 1994;343:269-270.
28. Maziere C, Auclair M, Ronveaux MF, Salmon S, Santus R, Maziere JC. Estrogen inhibits copper and cell-mediated modification of low density lipoprotein. Atherosclerosis. 1991;89:175-182.
29. Ayres S, Tang M, Subbiach MRT. Estradiol-17β as an antioxidant: some distinct features when compared with common fat-soluble antioxidants. J Lab Clin Med. 1996;128:367-375.
30. Özden S, Dilar K, Kadir YH, Gûlizar K. The effects of hormone replacement therapy on lipid peroxidation and antioxidant status. Maturitas. 2001;38:165-170.
31. Capel ID, Jenner M, Williams DC, Donaldson D, Nath A. The effect of prolonged oral contraceptive steroid use on erythrocyte glutathione peroxidase activity. J Steroid Biochem. 1981;14:729-732.
32. Huang YC, Chuang LY, Hung WC. Mechanisms underlying nonsteroidal anti-inflammatory drug-induced p27(Kip1) expression. Mol Pharmacol. 2002;62:1515-1521.
33. Sanders PM, Russell ST, Tisdale MJ. Angiotensin II directly induces muscle protein catabolism through the ubiquitin-proteasome proteolytic pathway and may play a role in cancer cachexia. Br J Cancer. 2005;93:425-434.