Depth-resolved characterization of diffusion properties within and across minimally-perturbed skin layers

Journal of Controlled Release

Volumn 166, Issue 2, 2013, Pages 87-94

  Raphael, Anthony P ^a   Meliga, Stefano C ^a   Chen, Xianfeng ^a   Fernando, Germain J P ^a   Flaim, Christopher ^a   Kendall, Mark A F ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

3D confocal microscopy; Dermis; Image processing; Macromolecular diffusion; Microneedles; Rhodamine dextran

Indexed keywords

3D IMAGING; ANTIGEN PRESENTING CELLS; CELLULAR ARRANGEMENT; COMPUTATIONAL APPROACH; CONTROLLED DELIVERY; DEPTH-RESOLVED; DERMIS; DIFFUSION PROPERTIES; FIBRILLAR NETWORKS; FLUORESCENT PROBES; HIGH-RESOLUTION TECHNIQUES; IN-VIVO; MICRONEEDLES; MOUSE SKIN; SKIN LAYER; SPECIFIC SITES; TEST CASE;

BIOLOGICAL MATERIALS; CONFOCAL MICROSCOPY; DEXTRAN; IMAGE PROCESSING; MACROMOLECULES;

DIFFUSION;

ANIMAL TISSUE; ARTICLE; CONFOCAL MICROSCOPY; DERMIS; DIFFUSION; DRUG DELIVERY SYSTEM; EPIDERMIS; MACROMOLECULE; NONHUMAN; PRIORITY JOURNAL; THREE DIMENSIONAL IMAGING;

ALGORITHMS; ANIMALS; DELAYED-ACTION PREPARATIONS; DERMIS; DEXTRANS; DIFFUSION; DRUG DELIVERY SYSTEMS; EPIDERMIS; FLUORESCENCE; FLUORESCENT DYES; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MICE; MICROSCOPY, CONFOCAL; RHODAMINES; SKIN ABSORPTION;

EID: 84872678644     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.12.010     Document Type: Article

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