Optical properties of mutant versus wild-type mouse skin measured by reflectance-mode confocal scanning laser microscopy (rCSLM)

Journal of Biomedical Optics

Volumn 13, Issue 4, 2008, Pages

  Samatham, Ravikant ^a   Jacques, Steven L ^a   Campagnola, Paul ^b  

^a Oregon Health and Science University Department of Biomedical Engineering   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

anisotropy of scattering; optical coherence tomography (OCT); osteogenesis imperfecta; reflectance mode confocal scanning laser microscopy (rCSLM); scattering coefficient

Indexed keywords

BONE DISEASE; COLLAGEN FIBER; COLLAGEN FIBRILS; CONFOCAL SCANNING LASER MICROSCOPY; EXPONENTIAL DECAYS; FOCAL VOLUME; ISOTROPIC SCATTERING; MEASURED DATA; MOUSE SKIN; MUTANT ALLELES; OPTICAL COHERENCE TOMOGRAPHY (OCT); OPTICAL SCATTERING; OSTEOGENESIS IMPERFECTA; REFLECTANCE SIGNALS; SCATTERING COEFFICIENT; TYPE I COLLAGEN; WILD TYPES;

ANISOTROPY; COHERENT SCATTERING; COLLAGEN; HISTOLOGY; LIGHT SCATTERING; MAMMALS; OPTICAL PROPERTIES; REFLECTION; SCANNING; TISSUE;

FORWARD SCATTERING;

ANIMAL; ARTICLE; C57BL MOUSE; COMPUTER ASSISTED DIAGNOSIS; CONFOCAL MICROSCOPY; METHODOLOGY; MOUSE; MUTATION; OSTEOGENESIS IMPERFECTA; PATHOLOGY; PATHOPHYSIOLOGY; SKIN; SKIN DISEASE;

ANIMALS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MUTATION; OSTEOGENESIS IMPERFECTA; SKIN; SKIN DISEASES;

EID: 58149382687     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.2953195     Document Type: Article

References (12)

1. W., Cheong, S., Prahl, and A., Welch, " A review of the optical properties of biological tissues, ", IEEE J. Quantum Electron., 26 (12), 2166-2185 (1990). ejq IEJQA7 0018-9197 10.1109/3.64354
2. B. C., Wilson and S. L., Jacques, " Optical reflectance and transmission of tissues: principles and applications, ", IEEE J. Quantum Electron., 26 (12), 2186-2199 (1990). ejq IEJQA7 0018-9197 10.1109/3.64355
3. S., Lin, L., Wang, S., Jacques, and F., Tittel, " Measurement of tissue optical properties using oblique incidence optical fiber reflectometry, ", Appl. Opt., 36 (1), 136-143 (1997). apo APOPAI 0003-6935
4. T., Collier, M., Follen, A., Malpica, and R., Richards-Kortum, " Sources of scattering in cervical tissue: determination of the scattering coefficient by confocal microscopy, ", Appl. Opt., 44 (11), 2072-2081 (2005). apo APOPAI 0003-6935 10.1364/AO.44.002072
5. S., Jacques, R., Samatham, N., Choudhury, and D. S., Gareau, " Specifying tissue optical properties using axial dependence of confocal reflectance images: confocal scanning laser microscopy and optical coherence tomography, ", Proc. SPIE, 6446, 64460N (2007). spi PSISDG 0277-786X
6. S. L., Jacques, R., Samatham, N., Choudhury, Y., Fu, and D., Levitz, " Measuring tissue optical properties, in vivo, using reflectance-mode confocal microscopy and OCT, ", Proc. SPIE, 6864, 10 (2008). spi PSISDG 0277-786X
7. D., Levitz, L., Thrane, M. H., Frosz, P. E., Andersen, C. B., Andersen, J., Valanciunaite, J., Swartling, S., Andersson-Engels, and P. R., Hansen, " Determination of optical scattering properties of highly-scattering media from optical coherence tomography images, ", Opt. Express, 12 (2), 249-259 (2004). 8mi OPEXFF 1094-4087 10.1364/OPEX.12.000249
8. D. J., Faber, F. J., van der Meer, M. C. G., Aalders, and T. G., van Leeuwen, " Quantitative measurement of attenuation coefficients of weakly scattering media using optical coherence tomography, ", Opt. Express, 12 (19), 4353-4365 (2004). 8mi OPEXFF 1094-4087 10.1364/OPEX.12.004353
9. A., Forlino and J. C., Marini, " Osteogenesis imperfecta: prospects for molecular therapeutics, ", Mol. Genet. Metab., 71, 225-232 (2000). 8i2 MGMEFF 1096-7192
10. O., Nadiarnykh, S., Plotnikov, W. A., Mohler, I., Kalajzic, D., Redford-Badwal, and P. J., Campagnola, " Second harmonic generation imaging microscopy studies of osteogenesis imperfecta, ", J. Biomed. Opt., 12, 051805 (2007). jbo JBOPFO 1083-3668 10.1117/1.2799538
11. S. L., Jacques, C. A., Alter, and S. A., Prahl, " Angular dependence of HeNe laser light scattering by human dermis, ", Lasers Life Sci., 1, 309-334 (1987). 9sm ZZZZZZ 0886-0467
12. M., Rajadhyaksha and S., Gonzalez, " Real-time, in vivo, confocal fluorescence microscopy, " Chapter, 5, in, Handbook of Biomedical Fluorescence, M. A., Mycek, and, B., Pogue, eds., pp. 143-218, Marcel Decker, New York (2003).