Metabolite concentrations in the anterior cingulate cortex predict high neuropathic pain impact after spinal cord injury

Pain

Volumn 154, Issue 2, 2013, Pages 204-212

  Widerström Noga, Eva ^a,b   Pattany, Pradip M ^b   Cruz Almeida, Yenisel ^a,b,c   Felix, Elizabeth R ^a,b   Perez, Salome ^a   Cardenas, Diana D ^a,b   Martinez Arizala, Alberto ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF DENTISTRY   (United States)

Author keywords

Cingulate cortex; Magnetic resonance spectroscopy; Neuropathic pain; Psychosocial impact; Spinal cord injury

Indexed keywords

ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; CHOLINE; GLUTAMIC ACID; GLUTAMINE; INOSITOL; N ACETYLASPARTIC ACID; OPIATE;

ADULT; ANTERIOR CINGULATE; ARTICLE; CONTROLLED STUDY; DISTRESS SYNDROME; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROPATHIC PAIN; NOCICEPTION; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PAIN ASSESSMENT; PRESCRIPTION; PRIORITY JOURNAL; PSYCHOMETRY; SOCIAL PSYCHOLOGY; SPINAL CORD INJURY;

EID: 84872675173     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2012.07.022     Document Type: Article

References (62)

1. W.P. Waring 3rd, F. Biering-Sorensen, S. Burns, W. Donovan, D. Graves, A. Jha, L. Jones, S. Kirshblum, R. Marino, M.J. Mulcahey, R. Reeves, W.M. Scelza, M. Schmidt-Read, and A. Stein 2009 Review and revisions of the international standards for the neurological classification of spinal cord injury J Spinal Cord Med 33 2010 346 352
2. A.V. Apkarian, M.N. Baliki, and P.Y. Geha Towards a theory of chronic pain Prog Neurobiol 87 2009 81 97
3. A.V. Apkarian, M.C. Bushnell, R.D. Treede, and J.K. Zubieta Human brain mechanisms of pain perception and regulation in health and disease Eur J Pain 9 2005 463 484
4. A.V. Apkarian, Y. Sosa, S. Sonty, R.M. Levy, R.N. Harden, T.B. Parrish, and D.R. Gitelman Chronic back pain is associated with decreased prefrontal and thalamic gray matter density J Neurosci 24 2004 10410 10415
5. C. Baastrup, and N.B. Finnerup Pharmacological management of neuropathic pain following spinal cord injury CNS Drugs 22 2008 455 475
6. M. Banasr, G.M. Chowdhury, R. Terwilliger, S.S. Newton, R.S. Duman, K.L. Behar, and G. Sanacora Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole Mol Psychiatry 15 2010 501 511
7. A.T. Beck, C.H. Ward, M. Mendelson, J. Mock, and J. Erbaugh An inventory for measuring depression Arch Gen Psychiatry 4 1961 561 571
8. K.A. Boschen, M. Tonack, and J. Gargaro Long-term adjustment and community reintegration following spinal cord injury Int J Rehabil Res 26 2003 157 164
9. G. Cruccu, C. Sommer, P. Anand, N. Attal, R. Baron, L. Garcia-Larrea, M. Haanpaa, and R.D. Treede EFNS guidelines on neuropathic pain assessment: revised 2009 Eur J Neurol 17 2010 1010 1018
10. K.D. Davis, S.J. Taylor, A.P. Crawley, M.L. Wood, and D.J. Mikulis Functional MRI of pain- and attention-related activations in the human cingulate cortex J Neurophysiol 77 1997 3370 3380
11. E. Diener, R.A. Emmons, R.J. Larsen, and S. Griffin The satisfaction with life scale J Pers Assess 49 1985 71 75
12. M.F. Folstein, S.E. Folstein, and P.R. McHugh "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician J Psychiatr Res 12 1975 189 198
13. U. Friebel, S.B. Eickhoff, and M. Lotze Coordinate-based meta-analysis of experimentally induced and chronic persistent neuropathic pain Neuroimage 58 2011 1070 1080
14. S.S. Gill, R.K. Small, D.G. Thomas, P. Patel, R. Porteous, B.N. Van, D.G. Gadian, R.A. Kauppinen, and S.R. Williams Brain metabolites as 1H NMR markers of neuronal and glial disorders NMR Biomed 2 1989 196 200
15. V. Govindaraju, K. Young, and A.A. Maudsley Proton NMR chemical shifts and coupling constants for brain metabolites NMR Biomed 13 2000 129 153
16. I.D. Grachev, B.E. Fredrickson, and A.V. Apkarian Abnormal brain chemistry in chronic back pain: an in vivo proton magnetic resonance spectroscopy study PAIN® 89 2000 7 18
17. A. Gussew, R. Rzanny, D. Gullmar, H.C. Scholle, and J.R. Reichenbach 1H-MR spectroscopic detection of metabolic changes in pain processing brain regions in the presence of non-specific chronic low back pain Neuroimage 54 2011 1315 1323
18. S.M. Gustin, P.J. Wrigley, L.A. Henderson, and P.J. Siddall Brain circuitry underlying pain in response to imagined movement in people with spinal cord injury PAIN® 148 2010 438 445
19. S.M. Gustin, P.J. Wrigley, P.J. Siddall, and L.A. Henderson Brain anatomy changes associated with persistent neuropathic pain following spinal cord injury Cereb Cortex 20 2010 1409 1419
20. Y.S. Gwak, and C.E. Hulsebosch GABA and central neuropathic pain following spinal cord injury Neuropharmacology 60 2011 799 808
21. Y.S. Gwak, J. Kang, G.C. Unabia, and C.E. Hulsebosch Spatial and temporal activation of spinal glial cells: role of gliopathy in central neuropathic pain following spinal cord injury in rats Exp Neurol 234 2012 362 372
22. B.C. Hains, and S.G. Waxman Activated microglia contribute to the maintenance of chronic pain after spinal cord injury J Neurosci 26 2006 4308 4317
23. C.E. Hulsebosch Gliopathy ensures persistent inflammation and chronic pain after spinal cord injury Exp Neurol 214 2008 6 9
24. C.E. Hulsebosch, B.C. Hains, E.D. Crown, and S.M. Carlton Mechanisms of chronic central neuropathic pain after spinal cord injury Brain Res Rev 60 2009 202 213
25. F. Hyder, A.B. Patel, A. Gjedde, D.L. Rothman, K.L. Behar, and R.G. Shulman Neuronal-glial glucose oxidation and glutamatergic-GABAergic function J Cereb Blood Flow Metab 26 2006 865 877
26. R.E. Isaacks, A.S. Bender, C.Y. Kim, and M.D. Norenberg Effect of osmolality and myoinositol deprivation on the transport properties of myoinositol in primary astrocyte cultures Neurochem Res 22 1997 1461 1469
27. D.C. Javitt Glutamate as a therapeutic target in psychiatric disorders Mol Psychiatry 9 2004 984 997
28. R.D. Kerns, D.C. Turk, and T.E. Rudy The West Haven-Yale Multidimensional Pain Inventory (WHYMPI) PAIN® 23 1985 345 356
29. J.H. Krystal, G. Sanacora, H. Blumberg, A. Anand, D.S. Charney, G. Marek, C.N. Epperson, A. Goddard, and G.F. Mason Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments Mol Psychiatry 7 2002 S71 S80
30. S.C. LaGraize, and P.N. Fuchs GABAA but not GABAB receptors in the rostral anterior cingulate cortex selectively modulate pain-induced escape/avoidance behavior Exp Neurol 204 2007 182 194
31. J.J. Luykx, K.G. Laban, M.P. van den Heuvel, M.P. Boks, R.C. Mandl, R.S. Kahn, and S.C. Bakker Region and state specific glutamate downregulation in major depressive disorder: a meta-analysis of (1)H-MRS findings Neurosci Biobehav Rev 36 2012 198 205
32. J. Nunnally, and I. Bernstein Psychometric theory 3rd ed. 1994 McGraw Hill New York
33. T.P. Oei, L. Evans, and G.M. Crook Utility and validity of the STAI with anxiety disorder patients Br J Clin Psychol 29 1990 429 432
34. P.M. Pattany, R.P. Yezierski, E.G. Widerstrom-Noga, B.C. Bowen, A. Martinez-Arizala, B.R. Garcia, and R.M. Quencer Proton magnetic resonance spectroscopy of the thalamus in patients with chronic neuropathic pain after spinal cord injury AJNR Am J Neuroradiol 23 2002 901 905
35. S.W. Provencher Estimation of metabolite concentrations from localized in vivo proton NMR spectra Magn Reson Med 30 1993 672 679
36. E.M. Ratai, L. Annamalai, T. Burdo, C.G. Joo, J.P. Bombardier, R. Fell, R. Hakimelahi, J. He, M.R. Lentz, J. Campbell, E. Curran, E.F. Halpern, E. Masliah, S.V. Westmoreland, K.C. Williams, and R.G. Gonzalez Brain creatine elevation and N-acetylaspartate reduction indicates neuronal dysfunction in the setting of enhanced glial energy metabolism in a macaque model of neuro AIDS Magn Reson Med 66 2011 625 634
37. B. Rosner Fundamentals of biostatistics 3rd ed. 1990 PWS-Kent Boston, Massachusetts
38. N. Sawamoto, M. Honda, T. Okada, T. Hanakawa, M. Kanda, H. Fukuyama, J. Konishi, and H. Shibasaki Expectation of pain enhances responses to nonpainful somatosensory stimulation in the anterior cingulate cortex and parietal operculum/posterior insula: an event-related functional magnetic resonance imaging study J Neurosci 20 2000 7438 7445
39. T. Schunck, G. Erb, A. Mathis, N. Jacob, C. Gilles, I.J. Namer, D. Meier, and R. Luthringer 733 Test-retest reliability of a functional MRI anticipatory anxiety paradigm in 734 healthy volunteers J Magn Reson Imaging 27 2008 459 468
40. G.E. Schwarz Estimating the dimension of a model Annals Stats. 6 1978 461 464
41. A.J. Shackman, T.V. Salomons, H.A. Slagter, A.S. Fox, J.J. Winter, and R.J. Davidson The integration of negative affect, pain and cognitive control in the cingulate cortex Nat Rev Neurosci 12 2011 154 167
42. P.E. Shrout, and J.L. Fleiss Intraclass correlations: uses in assessing rater reliability Psychol Bull 86 1979 420 427
43. P.J. Siddall, D.A. Taylor, and M.J. Cousins Classification of pain following spinal cord injury Spinal Cord 35 1997 69 75
44. M.L. Simmons, C.G. Frondoza, and J.T. Coyle Immunocytochemical localization of N-acetyl-aspartate with monoclonal antibodies Neuroscience 45 1991 37 45
45. L. Sorensen, P.J. Siddall, M.I. Trenell, and D.K. Yue Differences in metabolites in pain-processing brain regions in patients with diabetes and painful neuropathy Diabetes Care 31 2008 980 981
46. C.D. Spielberger, R.C. Garsuch, and R.E. Lushene Manual for the state-trait anxiety inventory 1970 Consulting Psychologists Press Palo Alto, CA
47. S.P.S.S. Inc Two step cluster analysis: technical report 2004 SPSS Chicago
48. P. Stanwell, P. Siddall, N. Keshava, D. Cocuzzo, S. Ramadan, A. Lin, D. Herbert, A. Craig, Y. Tran, J. Middleton, S. Gautam, M. Cousins, and C. Mountford Neuro magnetic resonance spectroscopy using wavelet decomposition and statistical testing identifies biochemical changes in people with spinal cord injury and pain Neuroimage 53 2010 544 552
49. M.J. Taylor, S. Selvaraj, R. Norbury, P. Jezzard, and P.J. Cowen Normal glutamate but elevated myoinositol in anterior cingulate cortex in recovered depressed patients J Affect Disord 119 2009 186 189
50. D.C. Turk Biopsychosocial perspective on chronic pain R. Gatchel, D.C. Turk, Psychological approaches to chronic pain management: a clinician's handbook 1996 Guilford Press New York 3 33
51. D.C. Turk, R.H. Dworkin, R.R. Allen, N. Bellamy, N. Brandenburg, D.B. Carr, C. Cleeland, R. Dionne, J.T. Farrar, B.S. Galer, D.J. Hewitt, A.R. Jadad, N.P. Katz, L.D. Kramer, D.C. Manning, C.G. McCormick, M.P. McDermott, P. McGrath, S. Quessy, B.A. Rappaport, J.P. Robinson, M.A. Royal, L. Simon, J.W. Stauffer, W. Stein, J. Tollett, and J. Witter Core outcome domains for chronic pain clinical trials: IMMPACT recommendations PAIN® 106 2003 337 345
52. J. Urenjak, S.R. Williams, D.G. Gadian, and M. Noble Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types J Neurosci 13 1993 981 989
53. E.G. Widerström-Noga, Y. Cruz-Almeida, E.R. Felix, and J.P. Adcock Relationship between pain characteristics and pain adaptation type in persons with SCI J Rehabil Res Dev 46 2009 43 56
54. E.G. Widerström-Noga, Y. Cruz-Almeida, A. Martinez-Arizala, and D.C. Turk Internal consistency, stability, and validity of the spinal cord injury version of the multidimensional pain inventory Arch Phys Med Rehabil 87 2006 516 523
55. E.G. Widerström-Noga, R. Duncan, E. Felipe-Cuervo, and D.C. Turk Assessment of the impact of pain and impairments associated with spinal cord injuries Arch Phys Med Rehabil 83 2002 395 404
56. E.G. Widerström-Noga, R. Duncan, and D.C. Turk Psychosocial profiles of people with pain associated with spinal cord injury: identification and comparison with other chronic pain syndromes Clin J Pain 20 2004 261 271
57. E.G. Widerström-Noga, E.R. Felix, Y. Cruz-Almeida, and D.C. Turk Psychosocial subgroups in persons with spinal cord injuries and chronic pain Arch Phys Med Rehabil 88 2007 1628 1635
58. P.J. Wrigley, S.R. Press, S.M. Gustin, V.G. Macefield, S.C. Gandevia, M.J. Cousins, J.W. Middleton, L.A. Henderson, and P.J. Siddall Neuropathic pain and primary somatosensory cortex reorganization following spinal cord injury PAIN® 141 2009 52 59
59. M.M. Wollaars, M.W. Post, and N. Brand Spinal cord injury pain: the influence of psychologic factors and impact on quality of life Clin J Pain 23 2007 383 391
60. C.J. Woolf, and M.B. Max Mechanism-based pain diagnosis: issues for analgesic drug development Anesthesiology 95 2001 241 249
61. R.P. Yezierski Spinal cord injury pain: spinal and supraspinal mechanisms J Rehabil Res Dev 46 2009 95 107
62. J.K. Zubieta, Y.R. Smith, J.A. Bueller, Y. Xu, M.R. Kilbourn, D.M. Jewett, C.R. Meyer, R.A. Koeppe, and C.S. Stohler Regional mu opioid receptor regulation of sensory and affective dimensions of pain Science 293 2001 311 315