The tumour suppressor DiRas3 interacts with C-RAF and downregulates MEK activity to restrict cell migration

Biology of the Cell

Volumn 105, Issue 2, 2013, Pages 91-107

  Klingauf, Mirko ^a,b   Beck, Matthias ^a,b   Berge, Ulrich ^a,b   Turgay, Yagmur ^a,b   Heinzer, Stephan ^a   Horvath, Peter ^a   Kroschewski, Ruth ^a  

^a ETH ZURICH   (Switzerland)

^b Molecular Life Science PhD Program   (Switzerland)

Author keywords

Cell migration; ERK; MAP kinase signalling; Tumour suppressor

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; NUCLEOTIDE; PROTEIN DIRAS3; PROTEIN KINASE B; PROTEIN TYROSINE PHOSPHATASE; RAF PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VIVO STUDY; MIGRATION INHIBITION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

CELL LINE, TUMOR; CELL MOVEMENT; DOWN-REGULATION; HUMANS; MAP KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-RAF; RHO GTP-BINDING PROTEINS; TUMOR SUPPRESSOR PROTEINS;

EID: 84872650393     PISSN: 02484900     EISSN: 1768322X     Source Type: Journal    
DOI: 10.1111/boc.201200030     Document Type: Article

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