Disparity in the use of combined modality therapy for rectal cancer in the older adult

Journal of Geriatric Oncology

Volumn 4, Issue 1, 2013, Pages 90-97

  Bohac, Gerald C ^a   Guaqueta, Delia ^a   Cheng, Debbie M ^b   Aschengrau, Ann ^b   Hartshorn, Kevan L ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BOSTON UNIVERSITY   (United States)

Author keywords

Chemotherapy; Radiation

Indexed keywords

FLUOROURACIL; FOLINIC ACID;

ADJUVANT CHEMORADIOTHERAPY; ADULT; AGE DISTRIBUTION; AGED; AGING; ARTICLE; CANCER ADJUVANT THERAPY; CANCER STAGING; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; FEMALE; HEALTH CARE DISPARITY; HEALTH CARE UTILIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIMODALITY CANCER THERAPY; POSTOPERATIVE CARE; PRIORITY JOURNAL; RECTUM CANCER; RECTUM SURGERY; RETROSPECTIVE STUDY; TREND STUDY;

AGED; COMBINED MODALITY THERAPY; FEMALE; HEALTHCARE DISPARITIES; HUMANS; MALE; RECTAL NEOPLASMS; RETROSPECTIVE STUDIES;

EID: 84872620965     PISSN: 18794068     EISSN: 18794076     Source Type: Journal    
DOI: 10.1016/j.jgo.2012.10.173     Document Type: Article

References (35)

1. Burdette-Radoux S., Muss H.B. Adjuvant chemotherapy in the elderly: whom to treat, what regimen?. Oncologist 2006, 11(3):234-242. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16549807.
2. Howlader N., Noone A., Krapcho M., Neyman N., Aminou T., Altekruse S.F., et al. SEER Cancer Statistics Review http://seer.cancer.gov/csr/19752009.
3. Chen H., Cantor A., Meyer J., Beth Corcoran M., Grendys E., Cavanaugh D., et al. Can older cancer patients tolerate chemotherapy? A prospective pilot study. Cancer 2003, 97(4):1107-1114. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12569613.
4. Dobie S.A., Warren J.L., Matthews B., Schwartz D., Baldwin L.M., Billingsley K. Survival benefits and trends in use of adjuvant therapy among elderly stage II and III rectal cancer patients in the general population. Cancer 2008, 112(4):789-799. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18189291.
5. Au H.J., Mulder K.E., Fields A.L. Systematic review of management of colorectal cancer in elderly patients. Clin Colorectal Cancer 2003, 3(3):165-171. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14706175.
6. Iwashyna T.J., Lamont E.B. Effectiveness of adjuvant fluorouracil in clinical practice: a population-based cohort study of elderly patients with stage III colon cancer. J Clin Oncol 2002, 20(19):3992-3998. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12351596.
7. Popescu R.A., Norman A., Ross P.J., Parikh B., Cunningham D. Adjuvant or palliative chemotherapy for colorectal cancer in patients 70 years or older. J Clin Oncol 1999, 17(8):2412-2418. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10561304.
8. Krook J.E., Moertel C.G., Gunderson L.L., Wieand H.S., Collins R.T., Beart R.W., et al. Effective surgical adjuvant therapy for high-risk rectal carcinoma. N Engl J Med 1991, 324(11):709-715. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1997835.
9. Douglass H.O., Moertel C.G., Mayer R.J., Thomas P.R., Lindblad A.S., Mittleman A., et al. Survival after postoperative combination treatment of rectal cancer. N Engl J Med 1986, 315(20):1294-1295. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3773947.
10. O'Connell M.J., Martenson J.A., Wieand H.S., Krook J.E., Macdonald J.S., Haller D.G., et al. Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery. N Engl J Med 1994, 331(8):502-507. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8041415.
11. Bosset J.F., Collette L., Calais G., Mineur L., Maingon P., Radosevic-Jelic L., et al. Chemotherapy with preoperative radiotherapy in rectal cancer. N Engl J Med 2006, 355(11):1114-1123. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16971718.
12. Sauer R., Becker H., Hohenberger W., Rodel C., Wittekind C., Fietkau R., et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 2004, 351(17):1731-1740. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15496622.
13. Minsky B.D., Cohen A.M., Kemeny N., Enker W.E., Kelsen D.P., Reichman B., et al. Combined modality therapy of rectal cancer: decreased acute toxicity with the preoperative approach. J Clin Oncol 1992, 10(8):1218-1224. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1634912.
14. Collette L., Bosset J.F., Den Dulk M., Nguyen F., Mineur L., Maingon P., et al. Patients with curative resection of cT3-4 rectal cancer after preoperative radiotherapy or radiochemotherapy: does anybody benefit from adjuvant fluorouracil-based chemotherapy? A trial of the European Organisation for Research and Treatment of Cancer Radiation Oncology Group. J Clin Oncol 2007, 25(28):4379-4386. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17906203.
15. Andre T., Boni C., Mounedji-Boudiaf L., Navarro M., Tabernero J., Hickish T., et al. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med 2004, 350(23):2343-2351. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15175436.
16. Schrag D., Gelfand S.E., Bach P.B., Guillem J., Minsky B.D., Begg C.B. Who gets adjuvant treatment for stage II and III rectal cancer? Insight from surveillance, epidemiology, and end results-Medicare. J Clin Oncol 2001, 19(17):3712-3718. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11533092.
17. Bouvier A.M., Jooste V., Bonnetain F., Cottet V., Bizollon M.H., Bernard M.P., et al. Adjuvant treatments do not alter the quality of life in elderly patients with colorectal cancer: a population-based study. Cancer 2008, 113(4):879-886. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18521903.
18. Goldberg R.M., Tabah-Fisch I., Bleiberg H., de Gramont A., Tournigand C., Andre T., et al. Pooled analysis of safety and efficacy of oxaliplatin plus fluorouracil/leucovorin administered bimonthly in elderly patients with colorectal cancer. J Clin Oncol 2006, 24(25):4085-4091. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16943526.
19. Sargent D.J., Goldberg R.M., Jacobson S.D., Macdonald J.S., Labianca R., Haller D.G., et al. A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients. N Engl J Med 2001, 345(15):1091-1097. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11596588.
20. Vironen J., Juhola M., Kairaluoma M., Jantunen I., Kellokumpu I. Tumour regression grading in the evaluation of tumour response after different preoperative radiotherapy treatments for rectal carcinoma. Int J Colorectal Dis 2005, 20(5):440-445. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15856263.
21. Ooi B.S., Tjandra J.J., Green M.D. Morbidities of adjuvant chemotherapy and radiotherapy for resectable rectal cancer: an overview. Dis Colon Rectum 1999, 42(3):403-418. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10223765.
22. Holm T., Rutqvist L.E., Johansson H., Cedermark B. Postoperative mortality in rectal cancer treated with or without preoperative radiotherapy: causes and risk factors. Br J Surg 1996, 83(7):964-968. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8813788.
23. Popek S., Tsikitis V.L., Hazard L., Cohen A.M. Preoperative radiation therapy for upper rectal cancer T3, T4/Nx: selectivity essential. Clin Colorectal Cancer 2012, 11(2):88-92. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=22154165.
24. Morris A.M., Billingsley K.G., Baxter N.N., Baldwin L.M. Racial disparities in rectal cancer treatment: a population-based analysis. Arch Surg 2004, 139(2):151-155. discussion 56, Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14769572.
25. Morris A.M., Billingsley K.G., Hayanga A.J., Matthews B., Baldwin L.M., Birkmeyer J.D. Residual treatment disparities after oncology referral for rectal cancer. J Natl Cancer Inst 2008, 100(10):738-744. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18477800.
26. Vironen J.H., Kairaluoma M., Aalto A.M., Kellokumpu I.H. Impact of functional results on quality of life after rectal cancer surgery. Dis Colon Rectum 2006, 49(5):568-578. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16583289.
27. Koroukian S.M., Bakaki P.M., Schluchter M.D., Owusu C. Treatment and Survival Patterns in Relation to Multimorbidity in Patients with Locoregional Breast and Colorectal Cancer. J Geriatr Oncol 2011, 2(3):200-208. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21785664.
28. Frasci G., Lorusso V., Panza N., Comella P., Nicolella G., Bianco A., et al. Gemcitabine plus vinorelbine yields better survival outcome than vinorelbine alone in elderly patients with advanced non-small cell lung cancer. A Southern Italy Cooperative Oncology Group (SICOG) phase III trial. Lung Cancer 2001, 34(Suppl. 4):S65-S69. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11742706.
29. Yancik R., Wesley M.N., Ries L.A., Havlik R.J., Long S., Edwards B.K., et al. Comorbidity and age as predictors of risk for early mortality of male and female colon carcinoma patients: a population-based study. Cancer 1998, 82(11):2123-2134. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9610691.
30. Hurria A., Gupta S., Zauderer M., Zuckerman E.L., Cohen H.J., Muss H., et al. Developing a cancer-specific geriatric assessment: a feasibility study. Cancer 2005, 104(9):1998-2005. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16206252.
31. Newcomb P.A., Carbone P.P. Cancer treatment and age: patient perspectives. J Natl Cancer Inst 1993, 85(19):1580-1584. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8411231.
32. Hurria A., Togawa K., Mohile S.G., Owusu C., Klepin H.D., Gross C.P., et al. Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study. J Clin Oncol 2011, 29(25):3457-3465. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21810685.
33. Battaglia T.A., Roloff K., Posner M.A., Freund K.M. Improving follow-up to abnormal breast cancer screening in an urban population. A patient navigation intervention. Cancer 2007, 109(2 Suppl.):359-367. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17123275.
34. Kachnic L.A., Tsai H.K., Coen J.J., Blaszkowsky L.S., Hartshorn K., Kwak E.L., et al. Dose-painted intensity-modulated radiation therapy for anal cancer: a multi-institutional report of acute toxicity and response to therapy. Int J Radiat Oncol Biol Phys 2012, 82(1):153-158. Available fromhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21095071.
35. Hofheinz RD, Wenz F, Post S, Matzdorff A, Laechelt S, Hartmann JT, et al. Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial. Lancet Oncol;13(6):579-88. Available from. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=22503032.