Perfluorooctane sulfonate (PFOS) affects hormone receptor activity, steroidogenesis, and expression of endocrine-related genes in vitro and in vivo

Environmental Toxicology and Chemistry

Volumn 32, Issue 2, 2013, Pages 353-360

  Du, Guizhen ^a,b   Hu, Jialei ^a,b   Huang, Hongyu ^a,b   Qin, Yufeng ^a,b   Han, Xiumei ^a,b   Wu, Di ^a,b   Song, Ling ^a,b   Xia, Yankai ^a,b   Wang, Xinru ^a,b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Nanjing Medical University   (China)

Author keywords

Endocrine disruptor; H295R steroidogenesis assay; Perfluorooctane sulfonate; Reporter gene assay; Zebrafish embryo

Indexed keywords

CONCENTRATION-DEPENDENT; ENDOCRINE DISRUPTOR; ENDOCRINE FUNCTIONS; ESTROGEN RECEPTOR; EXPRESSION LEVELS; EXPRESSION PATTERNS; HORMONE LEVELS; HORMONE RECEPTORS; IN-VITRO; IN-VIVO; NUCLEAR HORMONE RECEPTOR; PERFLUOROOCTANE SULFONATES; PERSISTENT CHEMICALS; REPORTER GENE ASSAYS; SCREENING METHODS; TESTOSTERONE; THYROID HORMONE RECEPTOR; THYROID HORMONES; ZEBRAFISH EMBRYOS;

ASSAYS; ENDOCRINOLOGY; HORMONES;

GENE EXPRESSION;

ALDOSTERONE SYNTHASE; BETA ACTIN; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYTOCHROME P450; CYTOCHROME P450 17; CYTOCHROME P450 19A; CYTOCHROME P450 19B; ESTRADIOL; ESTROGEN RECEPTOR; HORMONE RECEPTOR; PERFLUOROOCTANESULFONIC ACID; STEROID 21 MONOOXYGENASE; TESTOSTERONE; THYROID HORMONE RECEPTOR BETA; UNCLASSIFIED DRUG;

CONCENTRATION (COMPOSITION); CYPRINID; DOSE-RESPONSE RELATIONSHIP; EMBRYO; ENDOCRINE DISRUPTOR; GENE EXPRESSION; HORMONE; SULFONATE;

ARTICLE; CONTROLLED STUDY; ENDOCRINE GLAND; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STEROIDOGENESIS; ZEBRA FISH;

ALKANESULFONIC ACIDS; ANIMALS; BIOLOGICAL ASSAY; ENDOCRINE DISRUPTORS; ENDOCRINE SYSTEM; ESTRADIOL; FLUOROCARBONS; GENE EXPRESSION; RECEPTORS, ESTROGEN; TESTOSTERONE; THYROID GLAND; THYROID HORMONES; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH;

DANIO RERIO;

EID: 84872614808     PISSN: 07307268     EISSN: 15528618     Source Type: Journal    
DOI: 10.1002/etc.2034     Document Type: Article

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