Molecular conservation of estrogen-response associated with cell cycle regulation, hormonal carcinogenesis and cancer in zebrafish and human cancer cell lines

BMC Medical Genomics

Volumn 4, Issue , 2011, Pages

  Lam, Siew Hong ^b   Lee, Serene Gp ^a   Lin, Chin Y ^a,c,d   Thomsen, Jane S ^a   Fu, Pan Y ^a   Murthy, Karuturi Rk ^a   Li, Haixia ^a   Govindarajan, Kunde R ^a   Nick, Lin Ch ^a   Bourque, Guillaume ^a   Gong, Zhiyuan ^b   Lufkin, Thomas ^a   Liu, Edison T ^a   Mathavan, Sinnakaruppan ^a  

^a GENOME INSTITUTE OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c BRIGHAM YOUNG UNIVERSITY   (United States)

^d University of Houston   (United States)

Author keywords

anti estrogen ICI 182,780; carcinogenesis; estrogen; estrogen responsive genes; human cancer cell lines; microarray; model organism; molecular conservation; signaling pathways; zebrafish

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR; TRANSCRIPTOME; ESTROGEN; ZEBRAFISH PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CANCER CELL CULTURE; CCNA GENE; CCNB GENE; CCNE GENE; CDK2 GENE; CELL CYCLE REGULATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; E2F4 GENE; ESTROGEN RESPONSIVE ELEMENT; GENE; GENETIC CONSERVATION; GENOMIC INSTABILITY; HES1 GENE; HORMONAL CARCINOGENESIS; HUMAN; HUMAN CELL; MALE; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ZEBRA FISH; ANIMAL; CELL CYCLE; CLUSTER ANALYSIS; DNA MICROARRAY; DNA RESPONSIVE ELEMENT; DRUG EFFECT; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORK; GENETICS; METABOLISM; PRECANCER; REPRODUCIBILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; TUMOR CELL LINE; UPREGULATION;

DANIO RERIO;

ANIMALS; BINDING SITES; CELL CYCLE; CELL LINE, TUMOR; CLUSTER ANALYSIS; DOWN-REGULATION; ESTRADIOL; ESTROGENS; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; HUMANS; MALE; NEOPLASMS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PRECANCEROUS CONDITIONS; REPRODUCIBILITY OF RESULTS; RESPONSE ELEMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, NUCLEIC ACID; SIGNAL TRANSDUCTION; UP-REGULATION; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 79955787844     PISSN: None     EISSN: 17558794     Source Type: Journal    
DOI: 10.1186/1755-8794-4-41     Document Type: Article

References (54)

1. The biological role of estrogen receptors alpha and beta in cancer. ST Pearce VC Jordan, Crit Rev Oncol Hematol 2004 50 3 22 10.1016/j.critrevonc.2003. 09.003 15094156 (Pubitemid 38501614)
2. The role of estrogen in the initiation of breast cancer. J Russo IH Russo, J Steroid Biochem Mol Biol 2006 102 89 96 10.1016/j.jsbmb.2006.09.004 17113977 (Pubitemid 44750629)
3. Estrogen carcinogenesis in breast cancer. JD Yager NE Davidson, N Engl J Med 2006 354 270 282 10.1056/NEJMra050776 16421368
4. Regulation of vascular endothelial growth factor (VEGF) gene transcription by estrogen receptors alpha and beta. MD Mueller JL Vigne A Minchenko DI Lebovic DC Leitman RN Taylor, Proc Natl Acad Sci USA 2000 97 10972 10977 10995484
5. Estrogen and its metabolites are carcinogenic agents in human breast epithelial cells. J Russo M Hasan Lareef G Balogh S Guo IH Russo, J Steroid Biochem Mol Biol 2003 87 1 25 10.1016/S0960-0760(03)00390-X 14630087 (Pubitemid 37421335)
6. Estrogen-induced generation of reactive oxygen and nitrogen species, gene damage, and estrogen-dependent cancers. D Roy Q Cai Q Felty S Narayan, J Toxicol Environ Health B Crit Rev 2007 10 235 257 17620201 (Pubitemid 47057178)
7. Aurora a and B overexpression and centrosome amplification in early estrogen-induced tumor foci in the Syrian hamster kidney: implications for chromosomal instability, aneuploidy, and neoplasia. AE Hontz SA Li WL Lingle V Negron A Bruzek JL Salisbury JJ Li, Cancer Res 2007 67 2957 2963 10.1158/0008-5472.CAN-06-3296 17409401 (Pubitemid 46724831)
8. Cancer genetics and drug discovery in the zebrafish. HM Stern LI Zon, Nat Rev Cancer 2003 3 533 539 10.1038/nrc1126 12835673 (Pubitemid 37328841)
9. Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression. SH Lam YL Wu VB Vega LD Miller J Spitsbergen Y Tong H Zhan KR Govindarajan S Lee S Mathavan KR Murthy DR Buhler ET Liu Z Gong, Nat Biotechnol 2006 24 73 75 10.1038/nbt1169 16327811 (Pubitemid 43083168)
10. Transcriptome analysis of zebrafish embryogenesis using microarrays. S Mathavan SG Lee A Mak LD Miller KR Murthy KR Govindarajan Y Tong YL Wu SH Lam H Yang Y Ruan V Korzh Z Gong ET Liu T Lufkin, PLoS Genet 2005 1 260 276 16132083
11. Genetic models of cancer in zebrafish. JF Amatruda EE Patton, Int Rev Cell Mol Biol 2008 271 1 34 19081540
12. Zebrafish as a cancer model. H Feitsma E Cuppen, Mol Cancer Res 2008 6 685 694 10.1158/1541-7786.MCR-07-2167 18505914
13. The state of the art of the zebrafish model for toxicology and toxicologic pathology research - advantages and current limitations. JM Spitsbergen ML Kent, Toxicol Pathol 2003 31 Suppl 62 87 12597434 (Pubitemid 36169407)
14. Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology. SH Lam S Mathavan Y Tong H Li RK Karuturi Y Wu VB Vega ET Liu Z Gong, PLoS Genet 2008 4 1000121 10.1371/journal.pgen.1000121 18618001
15. Molecular characterization of three estrogen receptor forms in zebrafish: binding characteristics, transactivation properties, and tissue distributions. A Menuet E Pellegrini I Anglade O Blaise V Laudet O Kah F Pakdel, Biol Reprod 2002 66 1881 1892 10.1095/biolreprod66.6.1881 12021076 (Pubitemid 34547290)
16. Characterization of oestrogen receptors in zebrafish (Danio rerio). PL Bardet B Horard M Robinson-Rechavi V Laudet JM Vanacker, J Mol Endocrinol 2002 28 153 163 10.1677/jme.0.0280153 12063182 (Pubitemid 34662220)
17. Unexpected novel relational links uncovered by extensive developmental profiling of nuclear receptor expression. S Bertrand B Thisse R Tavares L Sachs A Chaumot PL Bardet H Escriv M Duffraisse O Marchand R Safi C Thisse V Laudet, PLoS Genet 2007 3 188 10.1371/journal.pgen.0030188 17997606
18. Zebrafish spotted-microarray for genome-wide expression profiling experiments. Part I: array printing and hybridization. SH Lam S Mathavan Z Gong, Methods Mol Biol 2009 546 175 195 10.1007/978-1-60327-977-2-12 19378105
19. Zebrafish spotted-microarray for genome-wide expression profiling experiments: data acquisition and analysis. SH Lam R Krishna Murthy Karuturi Z Gong, Methods Mol Biol 2009 546 197 226 10.1007/978-1-60327-977-2-13 19378106
20. Discovery of estrogen receptor alpha target genes and response elements in breast tumor cells. CY Lin A Ström VB Vega SL Kong AL Yeo JS Thomsen WC Chan B Doray DK Bangarusamy A Ramasamy LA Vergara S Tang A Chong VB Bajic LD Miller JA Gustafsson ET Liu, Genome Biol 2004 5 66 10.1186/gb-2004-5-9-r66 15345050
21. Genome-wide analysis of estrogen receptor binding sites. JS Carroll CA Meyer J Song W Li TR Geistlinger J Eeckhoute AS Brodsky EK Keeton KC Fertuck GF Hall Q Wang S Bekiranov V Sementchenko EA Fox PA Silver TR Gingeras XS Liu M Brown, Nat Genet 2006 38 1289 1297 10.1038/ng1901 17013392 (Pubitemid 44646291)
22. Whole-genome cartography of estrogen receptor alpha binding sites. CY Lin VB Vega JS Thomsen T Zhang SL Kong M Xie KP Chiu L Lipovich DH Barnett F Stossi A Yeo J George VA Kuznetsov YK Lee TH Charn N Palanisamy LD Miller E Cheung BS Katzenellenbogen Y Ruan G Bourque CL Wei ET Liu, PLoS Genet 2007 3 87 10.1371/journal.pgen.0030087 17542648
23. The history and mechanism of action of fulvestrant. RW Carlson, Clin Breast Cancer 2005 6 Suppl 1 5 8 15865849
24. Hepatic and extrahepatic expression of vitellogenin genes in the zebrafish, Danio rerio. H Wang JT Tan A Emelyanov V Korzh Z Gong, Gene 2005 356 91 100 15979250 (Pubitemid 41178978)
25. Testing estrogenicity of known and novel (xeno-)estrogens in the MolDarT using developing zebrafish (Danio rerio). J Muncke M Junghans RI Eggen, Environ Toxicol 2007 22 185 193 10.1002/tox.20255 17366571 (Pubitemid 46516694)
26. Endogenous estrogens as carcinogens through metabolic activation. JD Yager, J Natl Cancer Inst Monogr 2000 67 73
27. Ajuba, a cytosolic LIM protein, shuttles into the nucleus and affects embryonal cell proliferation and fate decisions. J Kanungo SJ Pratt H Marie GD Longmore, Mol Biol Cell 2000 11 3299 3313 11029037
28. Estrogen stimulates transcription of c-jun protooncogene. A Weisz L Cicatiello E Persico M Scalona F Bresciani, Mol Endocrinol 1990 4 1041 1050 10.1210/mend-4-7-1041 2126598
29. Rat embryo fibroblasts transformed by c-Jun display highly metastatic and angiogenic activities in vivo and deregulate gene expression of both angiogenic and antiangiogenic factors. M Kraemer R Tournaire V Dejong N Montreau D Briane C Derbin B Binetruy, Cell Growth Differ 1999 10 193 200 10099833 (Pubitemid 29138526)
30. Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. T Hirota N Kunitoku T Sasayama T Marumoto D Zhang M Nitta K Hatakeyama H Saya, Cell 2003 114 585 598 10.1016/S0092-8674(03)00642-1 13678582 (Pubitemid 37159255)
31. Functional significance of Aurora kinase A in centrosome amplification and genomic instability. S Sen H Katayama K Sasai, Adv Exp Med Biol 2008 617 99 108 10.1007/978-0-387-69080-3-9 18497034
32. Multiplatform genome-wide identification and modeling of functional human estrogen receptor binding sites. VB Vega CY Lin KS Lai SL Kong M Xie X Su HF Teh JS Thomsen AL Yeo WK Sung G Bourque ET Liu, Genome Biol 2006 7 82 10.1186/gb-2006-7-9-r82 16961928
33. Estrogen receptor and aryl hydrocarbon receptor signaling pathways. J Matthews JA Gustafsson, Nucl Recept Signal 2006 4 016 16862222
34. Aryl hydrocarbon receptor, cell cycle regulation, toxicity, and tumorigenesis. JL Marlowe A Puga, J Cell Biochem 2005 96 1174 1184 10.1002/jcb.20656 16211578 (Pubitemid 41681860)
35. The basic helix-loop-helix-PAS protein ARNT functions as a potent coactivator of estrogen receptor-dependent transcription. S Brunnberg K Pettersson E Rydin J Matthews A Hanberg I Pongratz, Proc Natl Acad Sci USA 2003 100 6517 6522 10.1073/pnas.1136688100 12754377 (Pubitemid 36666613)
36. The ligand status of the aromatic hydrocarbon receptor modulates transcriptional activation of BRCA-1 promoter by estrogen. JK Hockings PA Thorne MQ Kemp SS Morgan O Selmin DF Romagnolo, Cancer Res 2006 66 2224 2232 10.1158/0008-5472.CAN-05-1619 16489025
37. The aryl hydrocarbon receptor inhibits prostate carcinogenesis in TRAMP mice. WA Fritz TM Lin RD Cardiff RE Peterson, Carcinogenesis 2007 28 497 505 17052998 (Pubitemid 46321868)
38. The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis. Y Fan GP Boivin ES Knudsen DW Nebert Y Xia A Puga, Cancer Res 70 212 220
39. Repression of Ah receptor and induction of transforming growth factor-beta genes in DEN-induced mouse liver tumors. L Peng CN Mayhew M Schnekenburger ES Knudsen A Puga, Toxicology 2008 246 242 247 10.1016/j.tox.2008.01.002 18282651
40. Functional characterization of aryl hydrocarbon receptor (zfAHR2) localization and degradation in zebrafish (Danio rerio). JN Wentworth R Buzzeo RS Pollenz, Biochem Pharmacol 2004 67 1363 1372 10.1016/j.bcp.2003.12.002 15013852 (Pubitemid 38315102)
41. Redefining the role of the endogenous XAP2 and C-terminal hsp70-interacting protein on the endogenous Ah receptors expressed in mouse and rat cell lines. RS Pollenz EJ Dougherty, J Biol Chem 2005 280 33346 33356 10.1074/jbc.M506619200 16085934 (Pubitemid 41397132)
42. HES-1 inhibits 17beta-estradiol and heregulin-beta1-mediated upregulation of E2F-1. J Hartman P Muller JS Foster J Wimalasena JA Gustafsson A Strom, Oncogene 2004 23 8826 8833 10.1038/sj.onc.1208139 15467735 (Pubitemid 39610444)
43. HES-1, a novel target gene for the aryl hydrocarbon receptor. JS Thomsen S Kietz A Strom JA Gustafsson, Mol Pharmacol 2004 65 165 171 10.1124/mol.65.1.165 14722248 (Pubitemid 38113897)
44. Estrogen-dependent downregulation of hairy and enhancer of split homolog-1 gene expression in breast cancer cells is mediated via a 3' distal element. P Muller KW Merrell JD Crofts C Ronnlund CY Lin JA Gustafsson A Strom, J Endocrinol 2009 200 311 319 19039095
45. Mechanisms of primary and secondary estrogen target gene regulation in breast cancer cells. V Bourdeau J Deschenes D Laperriere M Aid JH White S Mader, Nucleic Acids Res 2008 36 76 93 10.1093/nar/gkn369 17986456
46. Expression of E2F-4 in invasive breast carcinomas is associated with poor prognosis. EA Rakha SE Pinder EC Paish JF Robertson IO Ellis, J Pathol 2004 203 754 761 10.1002/path.1573 15221934 (Pubitemid 38961561)
47. E2F4 expression is required for cell cycle progression of normal intestinal crypt cells and colorectal cancer cells. H Garneau MC Paquin JC Carrier N Rivard, J Cell Physiol 2009 221 350 358 10.1002/jcp.21859 19562678
48. Emerging roles of E2Fs in cancer: an exit from cell cycle control. HZ Chen SY Tsai G Leone, Nat Rev Cancer 2009 9 785 797 10.1038/nrc2696 19851314
49. Toward an understanding of the functional complexity of the E2F and retinoblastoma families. JR Nevins, Cell Growth Differ 1998 9 585 593 9716176 (Pubitemid 28367248)
50. Cell cycle sibling rivalry: Cdc2 vs. Cdk2. P Kaldis E Aleem, Cell Cycle 2005 4 1491 1494 10.4161/cc.4.11.2124 16258277
51. Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions. JW Thornton, Proc Natl Acad Sci USA 2001 98 5671 5676 10.1073/pnas.091553298 11331759 (Pubitemid 32435700)
52. Resurrecting the ancestral steroid receptor: ancient origin of estrogen signaling. JW Thornton E Need D Crews, Science 2003 301 1714 1717 10.1126/science.1086185 14500980 (Pubitemid 37174363)
53. An amphioxus orthologue of the estrogen receptor that does not bind estradiol: insights into estrogen receptor evolution. M Paris K Pettersson M Schubert S Bertrand I Pongratz H Escriva V Laudet, BMC Evol Biol 2008 8 219 10.1186/1471-2148-8-219 18655705
54. Hormone-activated estrogen receptors in annelid invertebrates: implications for evolution and endocrine disruption. J Keay JW Thornton, Endocrinology 2009 150 1731 1738 10.1210/en.2008-1338 19036877