Increased angiogenesis and angiogenic gene expression in carotid artery plaques from symptomatic stroke patients

Neurosurgery

Volumn 58, Issue 5, 2006, Pages 971-976

  Türeyen, Kudret ^a,b   Vemuganti, Raghu ^c   Salamat, M Shahriar ^d   Dempsey, Robert J ^a,c  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b SULEYMAN DEMIREL UNIVERSITY   (Turkey)

^c University of Wisconsin Cardiovascular Research Center   (United States)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Angiogenesis; Carotid plaque; Endarterectomy; GeneChip; Plaque rupture; Polymerase chain reaction

Indexed keywords

ANGIOGENIC FACTOR; CD34 ANTIGEN;

ADULT; ANGIOGENESIS; ARTICLE; ATHEROSCLEROTIC PLAQUE; CAROTID ARTERY OBSTRUCTION; CAROTID ENDARTERECTOMY; CLINICAL ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MICROVASCULATURE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; STROKE;

ADULT; AGED; CAROTID STENOSIS; CEREBROVASCULAR ACCIDENT; ENDARTERECTOMY, CAROTID; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MALE; MIDDLE AGED; NEOVASCULARIZATION, PHYSIOLOGIC;

EID: 33646823464     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/01.NEU.0000210246.61817.FE     Document Type: Article

References (37)

1. Avril G, Batt M, Guidoin R, Marois M, Hassen-Khodja R, Daune B, Gagliardi JM, Le Bas P: Carotid endarterectomy plaques: Correlations of clinical and anatomic findings. Ann Vasc Surg 5:50-54, 1991.
2. Bassiouny HS, Sakaguchi Y, Mikucki SA, McKinsey JF, Piano G, Gewertz BL, Glagov S: Juxtalumenal location of plaque necrosis and neoformation in symptomatic carotid stenosis. J Vasc Surg 26:585-594, 1997.
3. Carr S, Farb A, Pearce WH, Virmani R, Yao JS: Atherosclerotic plaque rupture in symptomatic carotid artery stenosis. J Vasc Surg 23:755-766, 1996.
4. Dempsey RJ, Diana AL, Moore RW: Thickness of carotid artery atherosclerotic plaque and ischemic risk. Neurosurgery 27:343-348, 1990.
5. Dempsey RJ, Moore RW: Amount of smoking independently predicts carotid artery atherosclerosis severity. Stroke 23:693-696, 1992.
6. Dempsey RJ, Moore RW, Cordero S: Factors leading to early recurrence of carotid plaque after carotid endarterectomy. Surg Neurol 43:278-283, 1995.
7. Dhodda VK, Sailor KA, Bowen KK, Vemuganti R: Putative endogenous mediators of preconditioning-induced ischemic tolerance in rat brain identified by genomic and proteomic analysis. J Neurochem 89:73-89, 2004.
8. Falk E: Why do plaques rupture? Circulation 23:755-766, 1992.
9. Falk E, Shah PK, Fuster V: Coronary plaque disruption. Circulation 86:30-42, 1992.
10. Faber BC, Heeneman S, Daemen MJ, Cleutjens KB: Genes potentially involved in plaque rupture. Curr Opin Lipidol 13:545-552, 2002.
11. Galili O, Herrmann J, Woodrum J, Sattler KJ, Lerman LO, Lerman A: Adventitial vasa vasorum heterogeneity among different vascular beds. J Vasc Surg 40:529-535, 2004.
12. Golledge J, Greenhalgh RM, Davies AH: The symptomatic carotid plaque. Stroke 31:774-781, 2000.
13. Hansson GK, Jonasson L, Seifert PS, Stemme S: Immune mechanisms in atherosclerosis. Arteriosclerosis 9:567-578, 1989.
14. Hatsukami TS, Ferguson MS, Beach KW, Gordon D, Detmer P, Burns D, Alpers C, Strandness DE: Carotid plaque morphology and clinical events. Stroke 28:95-100, 1997.
15. Hiltunen MO, Tuomisto TT, Niemi M, Bransen JH, Rissanen TT, Toronen P, Vajanto I, Yla-Herttuala S: Changes in gene expression in atherosclerosis plaques analyzed using DNA array. Atherosclerosis 165:23-32, 2002.
16. Husain T, Abbott CR, Scott DJ, Gough MJ: Macrophage accumulation, within the cap of carotid atherosclerotic plaques is associated with the onset of cerebral ischemic events. J Vasc Surg 30:269-276, 1999.
17. Imparato AM, Riles TS, Mintzer R, Baumann FG: The importance of hemorrhage in the relationship between gross morphologic characteristics and cerebral symptoms in 376 carotid artery plaques. Ann Surg 197:195-203, 1983.
18. Jeziorska M, Woolley DE: Local neovascularization and cellular composition within vulnerable regions of atherosclerotic plaques of human carotid arteries. J Pathol 188:189-196, 1999.
19. Jeziorska M, Woolley DE: Neovascularization in early atherosclerotic lesions of human carotid arteries: Its potential contribution to plaque development. Hum Pathol 30:919-925, 1999.
20. Mazzone A, De Servi S, Ricevuti G, Mazzucchelli I, Fossati G, Pasotti D, Bramucci E, Angoli L, Marsico F, Specchia G: Increased expression of neutrophil and monocyte adhesion molecules in unstable coronary artery disease. Circulation 88:358-363, 1993.
21. McCarthy MJ, Loftus IM, Thompson MM, Jones L, London NJ, Bell PR, Naylor AR, Brindle NP: Angiogenesis and the atherosclerotic carotid plaque: An association between symptomatology and plaque morphology. J Vasc Surg 30:261-268, 1999.
22. Mofidi R, Crotty TB, McCarthy P, Sheehan SJ, Mehigan D, Keaveny TV: Association between, plaque instability, angiogenesis and symptomatic carotid occlusive disease. Br J Surg 88:945-950, 2001.
23. Montauban van Swijndregt AD, Fibers HR, Moll FL, de Letter J, Ackerstaff RG: Cerebral ischemic disease and morphometric analyses of carotid plaques. Ann Vasc Surg 13:468-474, 1999.
24. Moreno PR, Falk E, Palacios IF, Newell JB, Fuster V, Fallon JT: Macrophage infiltration in acute coronary syndromes. Implications for plaque rupture. Circulation 90:775-778, 1994.
25. Park AE, McCarthy WJ, Pearce WH, Matsumura JS, Yao JS: Carotid plaque morphology correlates with presenting symptomatology. J Vasc Surg 27:872-879, 1998.
26. Persson AV, Robichaux WT, Silverman M: The natural history of carotid plaque development. Arch Surg 118:1048-1052, 1983.
27. Raghavendra Rao VL, Bowen KK, Dhodda VK, Song G, Franklin JL, Gawa NR, Dempsey RJ: Gene expression analysis of spontaneously hypertensive rat cerebral cortex following transient ischemia. J Neurochem 83:1072-1086, 2002.
28. Randi AM, Biguzzi E, Falciani F, Merlini P, Blakemore S, Bramucci E, Lucreziotti S, Lennon M, Faioni EM, Ardissino D, Mannucci PM: Identification of differentially expressed genes in coronary atherosclerotic plaques from patients with stable or unstable angina by cDNA array analysis. J Thromb Haemost 1:829-835, 2003.
29. Schonbeck U, Mach F, Sukhova GK, Murphy C, Bonnefoy JY, Fabunmi RP, Libby P: Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes: A role for CD40 signaling in plaque rupture? Circ Res 81:448-454, 1997.
30. Schulz UG, Rothwell PM: Association between arterial bifurcation anatomy and angiographic plaque ulceration among 4627 carotid stenoses. Cerebrovasc Dis 15:244-251, 2003.
31. Song G, Cechvala C, Resnick DK, Dempsey RJ, Rao VL: GeneChip analysis after acute spinal cord injury in rat. J Neurochem 79:804-815, 2001.
32. Song G, Dhodda VK, Blei AT, Dempsey RJ, Rao VL: GeneChip analysis shows altered mRNA expression of transcripts of neurotransmitter and signal transduction pathways in the cerebral cortex of portacaval shunted rats. J Neurosci Res 68:730-737, 2002.
33. Stary HC: Commentary: Natural history and histological classification of atherosclerotic lesions. Arterioscler Thromb Vasc Biol 20:1177-1178, 2000.
34. Tenaglia AN, Peters KG, Sketch MH Jr, Annex BH: Neovascularization in atherectomy specimens from patients with unstable angina: Implications for pathogenesis of unstable angina. Am Heart J 135:10-14, 1998.
35. Vemuganti R, Dempsey RJ: Carotid atherosclerotic plaques from symptomatic patients share the molecular fingerprints to develop in a neoplastic fashion: A microarray analysis study. Neuroscience 131:359-374, 2005.
36. Vemuganti R, Dempsey RJ, Bowen KK: Inhibition of intercellular adhesion molecule-1 protein expression by antisense oligonucleotides is neuroprotective after transient middle cerebral artery occlusion in rat. Stroke 35:179-184, 2004.
37. Wuttge DM, Sirsjo A, Eriksson P, Stemme S: Gene expression in atherosclerotic lesion of ApoE deficient mice. Mol Med 7:383-392, 2001.