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Volumn 26, Issue 2, 2013, Pages 195-205

Sirolimus inhibits lymphangiogenesis in rat renal allografts, a novel mechanism to prevent chronic kidney allograft injury

Author keywords

chronic kidney allograft injury; lymphangiogenesis; sirolimus; VEGF C; VEGFR 3

Indexed keywords

CREATININE; CYCLOSPORIN A; RAPAMYCIN; VASCULOTROPIN C; VASCULOTROPIN RECEPTOR 3;

EID: 84872612047     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/tri.12005     Document Type: Article
Times cited : (24)

References (28)
  • 1
    • 10744229023 scopus 로고    scopus 로고
    • Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates
    • Kerjaschki D, Regele HM, Moosberger I, et al,. Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates. J Am Soc Nephrol 2004; 15: 603.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 603
    • Kerjaschki, D.1    Regele, H.M.2    Moosberger, I.3
  • 2
    • 33846203293 scopus 로고    scopus 로고
    • Lymphatic neoangiogenesis in human renal allografts: Results from sequential protocol biopsies
    • Stuht S, Gwinner W, Franz I, et al,. Lymphatic neoangiogenesis in human renal allografts: results from sequential protocol biopsies. Am J Transplant 2007; 7: 377.
    • (2007) Am J Transplant , vol.7 , pp. 377
    • Stuht, S.1    Gwinner, W.2    Franz, I.3
  • 3
    • 84861996162 scopus 로고    scopus 로고
    • Inflammatory lymphangiogenesis in a rat transplant model of interstitial fibrosis and tubular atrophy
    • Vass DG, Shrestha B, Haylor J, Hughes J, Marson L,. Inflammatory lymphangiogenesis in a rat transplant model of interstitial fibrosis and tubular atrophy. Transpl Int 2012; 25: 792.
    • (2012) Transpl Int , vol.25 , pp. 792
    • Vass, D.G.1    Shrestha, B.2    Haylor, J.3    Hughes, J.4    Marson, L.5
  • 4
    • 76749083490 scopus 로고    scopus 로고
    • Lymphangiogenesis: Molecular mechanisms and future promise
    • Tammela T, Alitalo K,. Lymphangiogenesis: molecular mechanisms and future promise. Cell 2010; 140: 460.
    • (2010) Cell , vol.140 , pp. 460
    • Tammela, T.1    Alitalo, K.2
  • 5
    • 11144355004 scopus 로고    scopus 로고
    • VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment
    • Cursiefen C, Chen L, Borges LP, et al,. VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment. J Clin Invest 2004; 113: 1040.
    • (2004) J Clin Invest , vol.113 , pp. 1040
    • Cursiefen, C.1    Chen, L.2    Borges, L.P.3
  • 6
    • 20144369085 scopus 로고    scopus 로고
    • Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
    • Baluk P, Tammela T, Ator E, et al,. Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. J Clin Invest 2005; 115: 247.
    • (2005) J Clin Invest , vol.115 , pp. 247
    • Baluk, P.1    Tammela, T.2    Ator, E.3
  • 7
    • 0030973506 scopus 로고    scopus 로고
    • Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
    • Jeltsch M, Kaipainen A, Joukov V, et al,. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science 1997; 276: 1423.
    • (1997) Science , vol.276 , pp. 1423
    • Jeltsch, M.1    Kaipainen, A.2    Joukov, V.3
  • 8
    • 0035122695 scopus 로고    scopus 로고
    • Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3
    • Makinen T, Jussila L, Veikkola T, et al,. Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. Nat Med 2001; 7: 199.
    • (2001) Nat Med , vol.7 , pp. 199
    • Makinen, T.1    Jussila, L.2    Veikkola, T.3
  • 10
    • 59649126728 scopus 로고    scopus 로고
    • Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial
    • Schena FP, Pascoe MD, Alberu J, et al,. Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial. Transplantation 2009; 87: 233.
    • (2009) Transplantation , vol.87 , pp. 233
    • Schena, F.P.1    Pascoe, M.D.2    Alberu, J.3
  • 11
    • 0036174289 scopus 로고    scopus 로고
    • Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: Involvement of vascular endothelial growth factor
    • Guba M, von Breitenbuch P, Steinbauer M, et al,. Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor. Nat Med 2002; 8: 128.
    • (2002) Nat Med , vol.8 , pp. 128
    • Guba, M.1    Von Breitenbuch, P.2    Steinbauer, M.3
  • 12
    • 34247279338 scopus 로고    scopus 로고
    • Inhibition of the mammalian target of rapamycin impedes lymphangiogenesis
    • Huber S, Bruns CJ, Schmid G, et al,. Inhibition of the mammalian target of rapamycin impedes lymphangiogenesis. Kidney Int 2007; 71: 771.
    • (2007) Kidney Int , vol.71 , pp. 771
    • Huber, S.1    Bruns, C.J.2    Schmid, G.3
  • 13
    • 34147121375 scopus 로고    scopus 로고
    • Rapamycin, a specific inhibitor of the mammalian target of rapamycin, suppresses lymphangiogenesis and lymphatic metastasis
    • Kobayashi S, Kishimoto T, Kamata S, Otsuka M, Miyazaki M, Ishikura H,. Rapamycin, a specific inhibitor of the mammalian target of rapamycin, suppresses lymphangiogenesis and lymphatic metastasis. Cancer Sci 2007; 98: 726.
    • (2007) Cancer Sci , vol.98 , pp. 726
    • Kobayashi, S.1    Kishimoto, T.2    Kamata, S.3    Otsuka, M.4    Miyazaki, M.5    Ishikura, H.6
  • 14
    • 0037181101 scopus 로고    scopus 로고
    • The effect of acute rejection and cyclosporin A-treatment on induction of platelet-derived growth factor and its receptors during the development of chronic rat renal allograft rejection
    • Savikko J, Kallio EA, Taskinen E, von Willebrand E,. The effect of acute rejection and cyclosporin A-treatment on induction of platelet-derived growth factor and its receptors during the development of chronic rat renal allograft rejection. Transplantation 2002; 73: 506.
    • (2002) Transplantation , vol.73 , pp. 506
    • Savikko, J.1    Kallio, E.A.2    Taskinen, E.3    Von Willebrand, E.4
  • 15
    • 0028587197 scopus 로고
    • Histological chronic allograft damage index accurately predicts chronic renal allograft rejection
    • Isoniemi H, Taskinen E, Hayry P,. Histological chronic allograft damage index accurately predicts chronic renal allograft rejection. Transplantation 1994; 58: 1195.
    • (1994) Transplantation , vol.58 , pp. 1195
    • Isoniemi, H.1    Taskinen, E.2    Hayry, P.3
  • 16
    • 75749119257 scopus 로고    scopus 로고
    • Banff '09 Meeting Report: Antibody mediated graft deterioration and implementation of Banff working groups
    • Sis B, Mengel M, Haas M, et al,. Banff '09 Meeting Report: antibody mediated graft deterioration and implementation of Banff working groups. Am J Transplant 2010; 10: 464.
    • (2010) Am J Transplant , vol.10 , pp. 464
    • Sis, B.1    Mengel, M.2    Haas, M.3
  • 18
    • 0014088062 scopus 로고
    • The role of lymphatics in renal transplantation. Renal lymphatic regeneration
    • Mobley JE, O'Dell RM,. The role of lymphatics in renal transplantation. Renal lymphatic regeneration. J Surg Res 1967; 7: 231.
    • (1967) J Surg Res , vol.7 , pp. 231
    • Mobley, J.E.1    O'Dell, R.M.2
  • 19
    • 77950224116 scopus 로고    scopus 로고
    • Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts
    • Nykanen AI, Sandelin H, Krebs R, et al,. Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts. Circulation 2010; 121: 1413.
    • (2010) Circulation , vol.121 , pp. 1413
    • Nykanen, A.I.1    Sandelin, H.2    Krebs, R.3
  • 20
    • 0033814892 scopus 로고    scopus 로고
    • VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues
    • Partanen TA, Arola J, Saaristo A, et al,. VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues. FASEB J 2000; 14: 2087.
    • (2000) FASEB J , vol.14 , pp. 2087
    • Partanen, T.A.1    Arola, J.2    Saaristo, A.3
  • 21
    • 48349129069 scopus 로고    scopus 로고
    • Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation
    • Tammela T, Zarkada G, Wallgard E, et al,. Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature 2008; 454: 656.
    • (2008) Nature , vol.454 , pp. 656
    • Tammela, T.1    Zarkada, G.2    Wallgard, E.3
  • 22
    • 0033846016 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-3 in lymphangiogenesis in wound healing
    • Paavonen K, Puolakkainen P, Jussila L, Jahkola T, Alitalo K,. Vascular endothelial growth factor receptor-3 in lymphangiogenesis in wound healing. Am J Pathol 2000; 156: 1499.
    • (2000) Am J Pathol , vol.156 , pp. 1499
    • Paavonen, K.1    Puolakkainen, P.2    Jussila, L.3    Jahkola, T.4    Alitalo, K.5
  • 23
    • 67349229376 scopus 로고    scopus 로고
    • NFATc1 regulates lymphatic endothelial development
    • Kulkarni RM, Greenberg JM, Akeson AL,. NFATc1 regulates lymphatic endothelial development. Mech Dev 2009; 126: 350.
    • (2009) Mech Dev , vol.126 , pp. 350
    • Kulkarni, R.M.1    Greenberg, J.M.2    Akeson, A.L.3
  • 24
    • 33644694497 scopus 로고    scopus 로고
    • A randomized controlled trial of late conversion from CNI-based to sirolimus-based immunosuppression following renal transplantation
    • Watson CJ, Firth J, Williams PF, et al,. A randomized controlled trial of late conversion from CNI-based to sirolimus-based immunosuppression following renal transplantation. Am J Transplant 2005; 5: 2496.
    • (2005) Am J Transplant , vol.5 , pp. 2496
    • Watson, C.J.1    Firth, J.2    Williams, P.F.3
  • 25
    • 65249134974 scopus 로고    scopus 로고
    • Efficacy on renal function of early conversion from cyclosporine to sirolimus 3 months after renal transplantation: Concept study
    • Lebranchu Y, Thierry A, Toupance O, et al,. Efficacy on renal function of early conversion from cyclosporine to sirolimus 3 months after renal transplantation: concept study. Am J Transplant 2009; 9: 1115.
    • (2009) Am J Transplant , vol.9 , pp. 1115
    • Lebranchu, Y.1    Thierry, A.2    Toupance, O.3
  • 26
    • 77954952597 scopus 로고    scopus 로고
    • Renal function, efficacy, and safety of sirolimus and mycophenolate mofetil after short-term calcineurin inhibitor-based quadruple therapy in de novo renal transplant patients: One-year analysis of a randomized multicenter trial
    • Guba M, Pratschke J, Hugo C, et al,. Renal function, efficacy, and safety of sirolimus and mycophenolate mofetil after short-term calcineurin inhibitor-based quadruple therapy in de novo renal transplant patients: one-year analysis of a randomized multicenter trial. Transplantation 2010; 90: 175.
    • (2010) Transplantation , vol.90 , pp. 175
    • Guba, M.1    Pratschke, J.2    Hugo, C.3
  • 27
    • 38149095060 scopus 로고    scopus 로고
    • Rapamycin inhibits PAI-1 expression and reduces interstitial fibrosis and glomerulosclerosis in chronic allograft nephropathy
    • Pontrelli P, Rossini M, Infante B, et al,. Rapamycin inhibits PAI-1 expression and reduces interstitial fibrosis and glomerulosclerosis in chronic allograft nephropathy. Transplantation 2008; 85: 125.
    • (2008) Transplantation , vol.85 , pp. 125
    • Pontrelli, P.1    Rossini, M.2    Infante, B.3
  • 28
    • 70350126186 scopus 로고    scopus 로고
    • Interstitial fibrosis quantification in renal transplant recipients randomized to continue cyclosporine or convert to sirolimus
    • Servais A, Meas-Yedid V, Toupance O, et al,. Interstitial fibrosis quantification in renal transplant recipients randomized to continue cyclosporine or convert to sirolimus. Am J Transplant 2009; 9: 2552.
    • (2009) Am J Transplant , vol.9 , pp. 2552
    • Servais, A.1    Meas-Yedid, V.2    Toupance, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.