Postprandial antioxidant gene expression is modified by Mediterranean diet supplemented with coenzyme Q10 in elderly men and women

Age

Volumn 35, Issue 1, 2013, Pages 159-170

  Yubero Serrano, Elena M ^a   Gonzalez Guardia, Lorena ^a   Rangel Zuñiga, Oriol ^a   Delgado Casado, Nieves ^a   Delgado Lista, Javier ^a   Perez Martinez, Pablo ^a   Garcia Rios, Antonio ^a   Caballero, Javier ^a   Marin, Carmen ^a   Gutierrez Mariscal, Francisco M ^a   Tinahones, Francisco J ^a,b   Villalba, Jose M ^c   Tunez, Isaac ^c   Perez Jimenez, Francisco ^a   Lopez Miranda, Jose ^a  

^a HOSPITAL UNIVERSITARIO REINA SOFÍA   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DE LA VICTORIA   (Spain)

^c UNIVERSITY OF CÓRDOBA   (Spain)

Author keywords

CoQ10; Gene expression; Mediterranean diet; Oxidative stress

Indexed keywords

ANTIOXIDANT; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOPLASM PROTEIN; FATTY ACID; GLUTATHIONE PEROXIDASE 1; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MANGANESE SUPEROXIDE DISMUTASE; NUCLEAR PROTEIN; PROTEIN P22; PROTEIN P47; SATURATED FATTY ACID; THIOREDOXIN REDUCTASE; TRANSCRIPTION FACTOR NRF2; UBIDECARENONE;

AGED; ANTIOXIDANT GENE; ARTICLE; CALORIC INTAKE; CONTROLLED STUDY; DIET RESTRICTION; DIET SUPPLEMENTATION; FAT INTAKE; FEMALE; FOOD COMPOSITION; FOOD QUALITY; GENE EXPRESSION; GLUTATHIONE PEROXIDASE 1 GENE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; MALE; MEDITERRANEAN DIET; NORMAL HUMAN; NRF2 GENE; OXIDATIVE STRESS; P22PHOX GENE; P47PHOX GENE; PERIPHERAL BLOOD MONONUCLEAR CELL; POSTPRANDIAL STATE; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; SUPEROXIDE DISMUTASE 1 GENE; SUPEROXIDE DISMUTASE 2 GENE; THIOREDOXIN REDUCTASE GENE; VOLUNTEER;

AGED; AGING; ANTIOXIDANTS; BLOTTING, WESTERN; CROSS-OVER STUDIES; DIET, MEDITERRANEAN; DIETARY SUPPLEMENTS; FASTING; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MALE; OXIDATIVE STRESS; POSTPRANDIAL PERIOD; REAL-TIME POLYMERASE CHAIN REACTION; RNA; UBIQUINONE; VITAMINS;

EID: 84872610786     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-011-9331-4     Document Type: Article

References (42)

1. Arsova-Sarafinovska A, Eken A, Matevska N, Erdem O, Sayal A, Savaser A, Banev S, Petrovski D, Dzikova S, Georgiev V et al (2009) Increased oxidative/nitrosative stress and decreased antioxidant enzyme activities in prostate cancer. Clin Biochem 42:1228-1235
2. Battino M, Bompadre S, Leone L, Villa RF, Gorini A (2001)Coenzymes Q9 and Q10, vitamin E and peroxidation in rats synaptic and non-synaptic occipital cerebral cortex mitochondrial during ageing. Biol Chem 382:925-931
3. Bjornstedt M, Hamberg M, Kumar S, Xue J, Holmgren A (1995) Human thioredoxin reductase directly reduces lipid hydroperoxides by NADPH and selenocystine strongly stimulates the reaction via catalytically generated selenols. J Biol Chem 270:11761-11764
4. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
5. Brandes RP, Kreuzer J (2005) Vascular NADPH oxidases: molecular mechanisms of activation. Cardiovasc Res 65:16-27
6. Burczynski ME, Dorner AJ (2006) Transcriptional profiling of peripheral blood cells in clinical pharmacogenomic studies. Pharmacogenomics 7:187-202
7. Chen C, Kong AN (2004) Dietary chemopreventive compounds and ARE/EpRE signaling. Free Radic Biol Med 36:1505-1516
8. Coate KC, Huggins KW (2010) Consumption of a high glycemic index diet increases abdominal adiposity but does not influence adipose tissue pro-oxidant and antioxidant gene expression in C57BL/6 mice. Nutr Res 30:141-150
9. Covas MI (2007) Benefits of the Mediterranean diet on cardiovascular disease. Future Cardiol 3:575-578
10. de Haan JB, Bladier C, Griffiths P, Kelner M, O'Shea RD, Cheung NS, Bronson RT, Silvestro MJ, Wild S, Zheng SS et al (1998) Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide. J Biol Chem 273:22528-22536
11. de Mello VD, Kolehmaimen M, Schwab U, Mager U, Laaksonen DE, Pulkkinen L, Niskanen L, Gylling H, Atalay M, Rauramaa R et al (2008) Effect of weight loss on cytokine messenger RNA expression in peripheral blood mononuclear cells of obese subjects with the metabolic syndrome. Metabolism 57:192-199
12. Dinkova-Kostova AT, Talalay P (2008) Direct and indirect antioxidant properties of inducers of cytoprotective proteins. Mol Nutr Food Res 52(Suppl 1):S128-138
13. Droge W (2002) Free radicals in the physiological control of cell function. Physiol Rev 82:47-95
14. Elahi MM, Kong YX, Matata BM (2009) Oxidative stress as a mediator of cardiovascular disease. Oxid Med Cell Longev 2:259-269
15. Estruch R, Martinez-Gonzalez MA, Corella D, Salas-Salvado J, Ruiz-Gutierrez V, Covas MI, Fiol M, Gomez-Gracia E, Lopez-Sabater MC, Vinyoles E et al (2006) Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial. Ann Intern Med 145:1-11
16. Folkers K, Brown R, Judy WV, Morita M (1993) Survival of cancer patients on therapy with coenzyme Q10. Biochem Biophys Res Commun 192:241-245
17. Forstermann U (2008) Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies. Nat Clin Pract Cardiovasc Med 5:338-349
18. Grienling KK (2004) Novel NAD(P)H oxidases in the cardiovascular system. Heart 90:491-493
19. Gutierrez-Mariscal FM, Perez-Martinez P, Delgado-Lista J, Yubero-Serrano EM, Camargo A, Delgado-Casado N, Cruz-Teno C, Santos-Gonzalez M, Rodriguez-Cantalejo F, Castaño JP, et al (2011). Mediterranean diet supplemented with coenzyme Q10 induces postprandial changes in p53 in response to oxidative DNA damage in elderly subjects. Age (Dordr) (in press)
20. Harman D (2009) Origin and evolution of the free radical theory of aging: a brief personal history, 1954-2009. Biogerontology 10:773-81
21. Human Nutrition Information Service, Department of Agriculture (1987) Composition of foods. US Government Printing Office, Washington, DC
22. Jimenez-Gomez Y, Lopez-Miranda J, Blanco-Colio JM, Marin C, Perez-Martinez P, Ruano J, Paniagua JA, Rodriguez F, Egido J, Perez-Jimenez F (2009) Olive oil and walnut breakfasts reduce the postprandial inflammatory response in mononuclear cells compared with a butter breakfast in healthy men. Atherosclerosis 204:e70-6
23. Kaikkonen J, Tuomainen TP, Nyyssonen K, Salonen JT (2002) Coenzyme Q10: absorption, antioxidative properties, determinants, and plasma levels. Free Radic Res 36:389-397
24. Kobayashi M, Yamamoto M (2005) Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation. Antioxid Redox Signal 7:385-394
25. Lombard DB, Chua KF, Mostoslavsky R, Franco S, Gostissa M, Alt FW (2005) DNA repair, genome stability, and aging. Cell 120:497-512
26. Mass K, Chan S, Parker J, Slater A, Moore J, Olsen N, Aune TM (2002) Cutting edge: molecular portrait of human autoimmune disease. J Immunol 169:5-9
27. Mates JM, Perez-Gomez C, Nuñez de Castro I (1999) Antioxidant enzymes and human diseases. Clin Biochem 32:595-603
28. Muller T, Buttner T, Gholipour AF, Kuhn W (2003) Coenzyme Q10 supplementation provides mild symptomatic benefit in patients with Parkinson's disease. Neurosci Lett 341:201-204
29. Nguyen T, Sherratt PJ, Nioi P, Yang CS, Pickett CB (2005) Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1. J Biol Chem 280:32485-32492
30. Nordberg J, Arner ES (2001) Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic Biol Med 31:1287-1312
31. Quiles JL, Ochoa JJ, Battino M, Gutierrez-Rios P, Nepomuceno EA, Frías ML, Huertas JR, Mataix J (2005) Life-long supplementation with a low dosage of coenzyme Q10 in the rat: effects on antioxidant status and DNA damage. Biofactors 25:73-86
32. Quinzii CM, Lopez LC, Naini A, DiMauro S, Hirano M (2008) Human CoQ10 deficiencies. Biofactors 32:113-118
33. Rao G, Xia E, Richardson A (1990) Effect of age on the expression of antioxidant enzymes in male Fischer F344 rats. Mech Ageing Dev 53:49-60
34. Stachowska E, Wesolowska T, Olszewska M, Safranow K, Millo B, Domanski L, Jakubowska K, Ciechanowski K, Chlubek D (2005) Elements of Mediterranean diet improve oxidative status in blood of kidney graft recipients. Br J Nutr 93:345-352
35. Trichopoulou A, Costacou T, Bamia C, Trichopoulos D (2003) Adherence to a Mediterranean diet and survival in a Greek population. N Engl J Med 348:2599-2608
36. Varela G (1980) Tablas de composición de alimentos. (Food composition tables). Instituto de Nutrición CSIC, Madrid
37. Visioli F, Galli C (2001) The role of antioxidants in the Mediterranean diet. Lipids 36(Suppl):S49-52
38. Wang YP, Cheng ML, Zhang BF, Mu M, Wu J (2010) Effects of blueberry on hepatic fibrosis and transcription factor Nrf2 in rats. World J Gastroenterol 16:2657-2663
39. Xu W, Hellerbrand C, Kohler UA, Bugnon P, Kan YW, Werner S, Beyer TA (2008) The Nrf2 transcription factor protects from toxin-induced liver injury and fibrosis. Lab Invest 88:1068-1078
40. Yubero-Serrano EM, Delgado-Casado N, Delgado-Lista J, Perez-Martinez P, Tasset-Cuevas I, Santos-Gonzalez M, Caballero J, Garcia-Rios A, Marin C, Gutierrez-Mariscal FM, et al (2010). Postprandial antioxidant effect of the Mediterranean diet supplemented with coenzyme Q(10) in elderly men and women. Age (Dordr) (in press)
41. Zhang DD (2006) Mechanistic studies of the Nrf2-Keap1 signaling pathway. Drug Metab Rev 38:769-789
42. Zhong L, Holmgren A (2000) Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations. J Biol Chem 275:18121-18128