A cost-effectiveness analysis of identifying Fusobacterium necrophorum in throat swabs followed by antibiotic treatment to reduce the incidence of Lemierre's syndrome and peritonsillar abscesses

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 32, Issue 1, 2013, Pages 71-78

  Bank, S ^a   Christensen, K ^b   Kristensen, L H ^a   Prag, J ^a  

^a VIBORG HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; METRONIDAZOLE;

ANTIBIOTIC THERAPY; ARTICLE; BLOOD CULTURE; COST EFFECTIVENESS ANALYSIS; DENMARK; DRUG COST; FUSOBACTERIUM NECROPHORUM; INCIDENCE; LEMIERRE SYNDROME; MONTE CARLO METHOD; MORTALITY; PERITONSILLAR ABSCESS; PHARYNGITIS; POPULATION SIZE; PRIORITY JOURNAL; QUALITY ADJUSTED LIFE YEAR; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; THROAT CULTURE;

ADOLESCENT; ANTI-BACTERIAL AGENTS; BACTERIOLOGICAL TECHNIQUES; COST OF ILLNESS; COST-BENEFIT ANALYSIS; DENMARK; FEMALE; FUSOBACTERIUM INFECTIONS; FUSOBACTERIUM NECROPHORUM; HUMANS; INCIDENCE; LEMIERRE SYNDROME; MALE; PERITONSILLAR ABSCESS; PHARYNX; YOUNG ADULT;

EID: 84872600958     PISSN: 09349723     EISSN: 14354373     Source Type: Journal    
DOI: 10.1007/s10096-012-1715-6     Document Type: Article

References (33)

1. Bisno AL, Gerber MA, Gwaltney JM Jr, Kaplan EL, Schwartz RH; Infectious Diseases Society of America (2002) Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis. Clin Infect Dis 35:113-125
2. Meier FA, Centor RM, Graham L Jr, Dalton HP (1990) Clinical and microbiological evidence for endemic pharyngitis among adults due to group C streptococci. Arch Intern Med 150:825-829
3. Lindbaek M, Høiby EA, Lermark G, Steinsholt IM, Hjortdahl P (2005) Clinical symptoms and signs in sore throat patients with large colony variant beta-haemolytic streptococci groups C or G versus group A. Br J Gen Pract 55:615-619
4. Ehlers Klug T, Rusan M, Fuursted K, Ovesen T (2009) Fusobacterium necrophorum: most prevalent pathogen in peritonsillar abscess in Denmark. Clin Infect Dis 49:1467-1472
5. Amess JA, O'Neill W, Giollariabhaigh CN, Dytrych JK (2007) A six-month audit of the isolation of Fusobacterium necrophorum from patients with sore throat in a district general hospital. Br J Biomed Sci 64:63-65
6. Batty A, Wren MW (2005) Prevalence of Fusobacterium necrophorum and other upper respiratory tract pathogens isolated from throat swabs. Br J Biomed Sci 62:66-70
7. Batty A, Wren MW, Gal M (2005) Fusobacterium necrophorum as the cause of recurrent sore throat: comparison of isolates from persistent sore throat syndrome and Lemierre's disease. J Infect 51:299-306
8. Centor RM (2009) Expand the pharyngitis paradigm for adolescents and young adults. Ann Intern Med 151:812-815
9. Hagelskjaer Kristensen L, Prag J (2008) Lemierre's syndrome and other disseminated Fusobacterium necrophorum infections in Denmark: a prospective epidemiological and clinical survey. Eur J Clin Microbiol Infect Dis 27:779-789
10. Chirinos JA, Lichtstein DM, Garcia J, Tamariz LJ (2002) The evolution of Lemierre syndrome: report of 2 cases and review of the literature. Medicine (Baltimore) 81:458-465
11. Riordan T (2007) Human infection with Fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre's syndrome. Clin Microbiol Rev 20:622-659
12. Karkos PD, Asrani S, Karkos CD, Leong SC, Theochari EG, Alexopoulou TD, Assimakopoulos AD (2009) Lemierre's syndrome: a systematic review. Laryngoscope 119:1552-1559
13. Hagelskjaer LH, Prag J, Malczynski J, Kristensen JH (1998) Incidence and clinical epidemiology of necrobacillosis, including Lemierre's syndrome, in Denmark 1990-1995. Eur J Clin Microbiol Infect Dis 17:561-565
14. Hagelskjaer Kristensen L, Prag J (2000) Human necrobacillosis, with emphasis on Lemierre's syndrome. Clin Infect Dis 31:524-532
15. Jensen A, Hagelskjaer Kristensen L, Nielsen H, Prag J (2008) Minimum requirements for a rapid and reliable routine identification and antibiogram of Fusobacterium necrophorum. Eur J Clin Microbiol Infect Dis 27:557-563
16. Riordan T, Wilson M (2004) Lemierre's syndrome: more than a historical curiosa. Postgrad Med J 80:328-334
17. Aliyu SH, Marriott RK, Curran MD, Parmar S, Bentley N, Brown NM, Brazier JS, Ludlam H (2004) Real-time PCR investigation into the importance of Fusobacterium necrophorum as a cause of acute pharyngitis in general practice. J Med Microbiol 53:1029-1035
18. Hagelskjaer Kristensen L, Prag J (2008) Localised Fusobacterium necrophorum infections: a prospective laboratory-based Danish study. Eur J Clin Microbiol Infect Dis 27:733-739
19. Love WE, Zaccheo MV (2006) Lemierre's syndrome: more judicious antibiotic prescribing habits may lead to the clinical reappearance of this often forgotten disease. Am J Med 119:e7-e9
20. Jensen A, Hagelskjaer Kristensen L, Prag J (2007) Detection of Fusobacterium necrophorum subsp. funduliforme in tonsillitis in young adults by real-time PCR. Clin Microbiol Infect 13:695-701
21. Bank S, Nielsen HM, Mathiasen BH, Leth DC, Kristensen LH, Prag J (2010) Fusobacterium necrophorum: detection and identification on a selective agar. APMIS 118:994-999
22. Miller TL, McNabb SJ, Hilsenrath P, Pasipanodya J, Weis SE (2009) Personal and societal health quality lost to tuberculosis. PLoS One 4:e5080
23. Heron M, Hoyert DL, Murphy SL, Xu J, Kochanek KD, Tejada-Vera B (2009) Deaths: final data for 2006. Natl Vital Stat Rep 57:1-134
24. Neuner JM, Hamel MB, Phillips RS, Bona K, Aronson MD (2003) Diagnosis and management of adults with pharyngitis. A cost-effectiveness analysis. Ann Intern Med 139:113-122
25. Vammen S, Juul S, Henneberg EW, Fasting H, Lindholt JS (2001) What are the direct costs of an abdominal aortic aneurysm repair in a Danish hospital? Ugeskr Laeger 163:5189-5193
26. Tengs TO, Adams ME, Pliskin JS, Safran DG, Siegel JE, Weinstein MC, Graham JD (1995) Five-hundred life-saving interventions and their cost-effectiveness. Risk Anal 15:369-390
27. Devlin N, Parkin D (2004) Does NICE have a cost-effectiveness threshold and what other factors influence its decisions? A binary choice analysis. Health Econ 13:437-452
28. Gehrt B, Jensen A, Kristensen LH, Prag J (2009) Can anaerobic culture of throat swabs prevent Lemierre's syndrome? Ugeskr Laeger 171:991-992
29. Tsevat J, Kotagal UR (1999) Management of sore throats in children: a cost-effectiveness analysis. Arch Pediatr Adolesc Med 153:681-688
30. Centor RM, Allison JJ, Cohen SJ (2007) Pharyngitis management: defining the controversy. J Gen Intern Med 22:127-130
31. Ehrlich JE, Demopoulos BP, Daniel KR Jr, Ricarte MC, Glied S (2002) Cost-effectiveness of treatment options for prevention of rheumatic heart disease from Group A streptococcal pharyngitis in a pediatric population. Prev Med 35:250-257
32. Van Howe RS, Kusnier LP 2nd (2006) Diagnosis and management of pharyngitis in a pediatric population based on cost-effectiveness and projected health outcomes. Pediatrics 117:609-619
33. Hayes CS, Williamson H Jr (2001) Management of Group A beta-hemolytic streptococcal pharyngitis. Am Fam Physician 63:1557-1564