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Metabolic syndrome in childhood predicts adult metabolic syndrome and type 2 diabetes mellitus 25 to 30 years later
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18206689 10.1016/j.jpeds.2007.09.010 1:CAS:528:DC%2BD1cXptlWlug%3D%3D This study indicates the predictive value of MetS during childhood on the same syndrome during adulthood
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•• Morrison JA, Friedman LA, Wang P, Glueck CJ. Metabolic syndrome in childhood predicts adult metabolic syndrome and type 2 diabetes mellitus 25 to 30 years later. J Pediatr. 2008;152:201-6. This study indicates the predictive value of MetS during childhood on the same syndrome during adulthood.
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20921439 10.1161/CIRCULATIONAHA.110.940809 Data from these 2 large longitudinal studies indicate a 2-3 fold increased risk of adult MetS for adolescents with the syndrome
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•• Magnussen CG, Koskinen J, Chen W, Thomson R, Schmidt MD, Srinivasan SR, et al. Pediatric metabolic syndrome predicts adulthood metabolic syndrome, subclinical atherosclerosis, and type 2 diabetes mellitus but is no better than body mass index alone: the Bogalusa Heart Study and the Cardiovascular Risk in Young Finns Study. Circulation. 2010;122:1604-11. Data from these 2 large longitudinal studies indicate a 2-3 fold increased risk of adult MetS for adolescents with the syndrome.
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Predictive ability of childhood metabolic components for adult metabolic syndrome and type 2 diabetes
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In line with reference 36, this study highlights the predictive value of MetS in youth on future cardiometabolci outcomes during adulthood e1-7
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• Schubert CM, Sun SS, Burns TL, Morrison JA, Huang TT. Predictive ability of childhood metabolic components for adult metabolic syndrome and type 2 diabetes. J Pediatr. 2009;155:S6 e1-7. In line with reference 36, this study highlights the predictive value of MetS in youth on future cardiometabolic outcomes during adulthood.
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22247492 10.1161/CIRCULATIONAHA.111.034546 1:CAS:528:DC%2BC38Xls1Cjs74%3D This study highlights that the coexistence of low birth weight, small head circumference, and parental history of overweight or obesity may be helpful in targeting children at risk for developing MetS in adolescence
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• Efstathiou SP, Skeva II, Zorbala E, Georgiou E, Mountokalakis TD. Metabolic syndrome in adolescence: can it be predicted from natal and parental profile? The Prediction of Metabolic Syndrome in Adolescence (PREMA) study. Circulation. 2012;125:902-10. This study highlights that the coexistence of low birth weight, small head circumference, and parental history of overweight or obesity may be helpful in targeting children at risk for developing MetS during adolescence.
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19139390 10.1161/CIRCULATIONAHA.108.191394 This is a nice update on the current state of the art of the MetS in children and adolescents
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