-
1
-
-
3042752280
-
Aging and infectious diseases in the developing world
-
Gavazzi G, Herrmann F, Krause KH. Aging and infectious diseases in the developing world. Clin Infect Dis. 2004; 39:83-91.
-
(2004)
Clin Infect Dis
, vol.39
, pp. 83-91
-
-
Gavazzi, G.1
Herrmann, F.2
Krause, K.H.3
-
2
-
-
68149179573
-
Immunosenescence: what does it mean to health outcomes in older adults
-
McElhaney JE and Effros RB. Immunosenescence: what does it mean to health outcomes in older adults? Curr Opin Immunol. 2009;21:418-424.
-
(2009)
Curr Opin Immunol
, vol.21
, pp. 418-424
-
-
McElhaney, J.E.1
Effros, R.B.2
-
3
-
-
32044453088
-
Antibody response to influenza vaccination in the elderly: a quantitative review
-
Goodwin K, Viboud C, Simonsen L. Antibody response to influenza vaccination in the elderly: a quantitative review. Vaccine. 2006; 24:1159-1169.
-
(2006)
Vaccine
, vol.24
, pp. 1159-1169
-
-
Goodwin, K.1
Viboud, C.2
Simonsen, L.3
-
4
-
-
34147175492
-
How vaccines work on the background of the aging immune system
-
Haynes L. How vaccines work on the background of the aging immune system. Exp Gerontol. 2007; 42:438-440.
-
(2007)
Exp Gerontol
, vol.42
, pp. 438-440
-
-
Haynes, L.1
-
5
-
-
67649393351
-
Vaccination in the elderly: an immunological perspective
-
Chen WH, Kozlovsky BF, Effros RB, Grubeck-Loebenstein B, Edelman R, Sztein MB. Vaccination in the elderly: an immunological perspective. Trends Immunol. 2009; 30:351-359.
-
(2009)
Trends Immunol
, vol.30
, pp. 351-359
-
-
Chen, W.H.1
Kozlovsky, B.F.2
Effros, R.B.3
Grubeck-Loebenstein, B.4
Edelman, R.5
Sztein, M.B.6
-
6
-
-
60549108257
-
Increased reactivity of dendritic cells from aged subjects to self-antigen, the human DNA
-
Agrawal A, Tay J, Ton S, Agrawal S, Gupta S. Increased reactivity of dendritic cells from aged subjects to self-antigen, the human DNA. J Immunol. 2009; 182: 1138-1145.
-
(2009)
J Immunol
, vol.182
, pp. 1138-1145
-
-
Agrawal, A.1
Tay, J.2
Ton, S.3
Agrawal, S.4
Gupta, S.5
-
7
-
-
77951886965
-
Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response
-
Panda A, Qian F, Mohanty S, van Duin D, Newman FK, Zhang L, Chen S, Towle V, Belshe RB, Fikrig E, Allore HG, Montgomery RR, Shaw AC. Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response. J Immunol. 184:2010; 2518-2527.
-
(2010)
J Immunol
, vol.184
, pp. 2518-2527
-
-
Panda, A.1
Qian, F.2
Mohanty, S.3
van Duin, D.4
Newman, F.K.5
Zhang, L.6
Chen, S.7
Towle, V.8
Belshe, R.B.9
Fikrig, E.10
Allore, H.G.11
Montgomery, R.R.12
Shaw, A.C.13
-
8
-
-
21044451726
-
The influence of age on T cell generation and TCR diversity
-
Naylor K, Li G, Vallejo AN, Lee WW, Koetz K, Bryl E, Witkowski J, Fulbright J, Weyand CM, Goronzy JJ. The influence of age on T cell generation and TCR diversity. J Immunol. 2005; 174:7446-7452.
-
(2005)
J Immunol
, vol.174
, pp. 7446-7452
-
-
Naylor, K.1
Li, G.2
Vallejo, A.N.3
Lee, W.W.4
Koetz, K.5
Bryl, E.6
Witkowski, J.7
Fulbright, J.8
Weyand, C.M.9
Goronzy, J.J.10
-
9
-
-
67649397918
-
B cells and aging: molecules and mechanisms
-
Cancro, MP, Hao Y, Scholz JL, Riley RL, Frasca D, Dunn-Walters DK, Blomberg BB. B cells and aging: molecules and mechanisms. Trends Immunol. 2009; 30: 313-318.
-
(2009)
Trends Immunol
, vol.30
, pp. 313-318
-
-
Cancro, M.P.1
Hao, Y.2
Scholz, J.L.3
Riley, R.L.4
Frasca, D.5
Dunn-Walters, D.K.6
Blomberg, B.B.7
-
10
-
-
33846249269
-
Aging murine B cells have decreased class switch induced by anti-CD40 or BAFF
-
Frasca D, Riley RL, Blomberg BB. Aging murine B cells have decreased class switch induced by anti-CD40 or BAFF. Exp Gerontol.2007; 42:192-203.
-
(2007)
Exp Gerontol
, vol.42
, pp. 192-203
-
-
Frasca, D.1
Riley, R.L.2
Blomberg, B.B.3
-
12
-
-
68249158536
-
Human dendritic cells induce the differentiation of interleukin-21-producing T follicular helper-like cells through interleukin-12
-
Schmitt N, Morita R, Burdery L, Bentebibel S, Zurawski SM, Banchereau J, Ueno H. Human dendritic cells induce the differentiation of interleukin-21-producing T follicular helper-like cells through interleukin-12. Immunity. 2009; 31:158-169.
-
(2009)
Immunity
, vol.31
, pp. 158-169
-
-
Schmitt, N.1
Morita, R.2
Burdery, L.3
Bentebibel, S.4
Zurawski, S.M.5
Banchereau, J.6
Ueno, H.7
-
13
-
-
70450265288
-
Early commitment of naíve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12
-
Ma CS, Suryani S, Avery DT, Chan A, Nanan R, Santner-Nanan B, Deenick EK, Tangye SG. Early commitment of naíve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12.Immunol Cell Biol. 2009; 87:590-600.
-
(2009)
Immunol Cell Biol
, vol.87
, pp. 590-600
-
-
Ma, C.S.1
Suryani, S.2
Avery, D.T.3
Chan, A.4
Nanan, R.5
Santner-Nanan, B.6
Deenick, E.K.7
Tangye, S.G.8
-
14
-
-
25444434157
-
nterleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation
-
Leonard, WJ, Spolski R.Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation. Nat. Rev. Immunol. 2005; 5: 688-698.
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 688-698
-
-
Leonard, W.J.1
Spolski, R.2
-
15
-
-
0035400054
-
Cutting edge: the common γ-chain is an indispensable subunit of the IL-21 receptor complex
-
Asao H, Okuyama C, Kumaki S, Ishii N, Tsuchiya S, Foster D, Sugamura K. Cutting edge: the common γ-chain is an indispensable subunit of the IL-21 receptor complex. J. Immunol. 2001; 167: 1-5.
-
(2001)
J. Immunol
, vol.167
, pp. 1-5
-
-
Asao, H.1
Okuyama, C.2
Kumaki, S.3
Ishii, N.4
Tsuchiya, S.5
Foster, D.6
Sugamura, K.7
-
16
-
-
0034606359
-
Folliculr B helper T cells express CXC chemokine receptors 5 localized to B cell follicles, and support immunoglobulin production
-
Brietfeld D, Ohl L, Kremmer E, Ellwart J, Sallusto F, Lipp M Fórster R. Folliculr B helper T cells express CXC chemokine receptors 5 localized to B cell follicles, and support immunoglobulin production. J. Exp. Med.2000; 192:1545-1552.
-
(2000)
J. Exp. Med
, vol.192
, pp. 1545-1552
-
-
Brietfeld, D.1
Ohl, L.2
Kremmer, E.3
Ellwart, J.4
Sallusto, F.5
Lipp, M.6
Fórster, R.7
-
17
-
-
0037159687
-
A critical role for IL-21 in regulating immunoglobulin production
-
Ozaki K, Spolski R, Feng CG, Qi CF, Cheng J, Sher A Morse HC 3rd, Liu C, Schwartzberg PL, Leonard WJ. A critical role for IL-21 in regulating immunoglobulin production. Science. 2002; 298:1630-1634.
-
(2002)
Science
, vol.298
, pp. 1630-1634
-
-
Ozaki, K.1
Spolski, R.2
Feng, C.G.3
Qi, C.F.4
Cheng, J.5
Sher, A.6
Morse, H.C.7
Liu, C.8
Schwartzberg, P.L.9
Leonard, W.J.10
-
18
-
-
0034597789
-
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
-
Parrish-Novak J, Dillon SR, Nelson A, Hammond A, Sprecher C, Gross JA, Johnston J, Madden K, Xu W, West J, Schrader S, Burkhead S, Heipel M, Brandt C, Kuijper JL, Kramer J, et al. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature. 2000; 408: 57-63.
-
(2000)
Nature
, vol.408
, pp. 57-63
-
-
Parrish-Novak, J.1
Dillon, S.R.2
Nelson, A.3
Hammond, A.4
Sprecher, C.5
Gross, J.A.6
Johnston, J.7
Madden, K.8
Xu, W.9
West, J.10
Schrader, S.11
Burkhead, S.12
Heipel, M.13
Brandt, C.14
Kuijper, J.L.15
Kramer, J.16
-
20
-
-
79952675131
-
Follicular helper CD4 T cells (TFH)
-
Crotty S. Follicular helper CD4 T cells (TFH). Annu Rev Immunol. 2011; 29:621-63.
-
(2011)
Annu Rev Immunol
, vol.29
, pp. 621-663
-
-
Crotty, S.1
-
21
-
-
0028910222
-
(1995) Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12
-
Bacon CM, McVicar DW, Ortaldo JR, Rees RC, O'Shea JJ, Johnston JA. (1995) Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12. J Exp Med.1995; 181:399-404.
-
(1995)
J Exp Med
, vol.181
, pp. 399-404
-
-
Bacon, C.M.1
Mcvicar, D.W.2
Ortaldo, J.R.3
Rees, R.C.4
O'shea, J.J.5
Johnston, J.A.6
-
22
-
-
0029116336
-
Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes
-
3rd
-
Bacon CM, Petricoin EF 3rd, Ortaldo JR, Rees RC, Larner AC, Johnston JA, O'Shea JJ. Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes. Proc Natl Acad Sci U S A. 1995; 92:7307-7311.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 7307-7311
-
-
Bacon, C.M.1
Petricoin, E.F.2
Ortaldo, J.R.3
Rees, R.C.4
Larner, A.C.5
Johnston, J.A.6
O'shea, J.J.7
-
23
-
-
58149214356
-
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
-
Wei G, Wei L, Zhu J, Zang C, Hu-Li J, Yao Z, Cui K, Kanno Y, Roh TY, Watford WT, Schones DE, Peng W, Sun HW, Paul WE, O'Shea JJ, Zhao K. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity. 2009; 30:155-167.
-
(2009)
Immunity
, vol.30
, pp. 155-167
-
-
Wei, G.1
Wei, L.2
Zhu, J.3
Zang, C.4
Hu-Li, J.5
Yao, Z.6
Cui, K.7
Kanno, Y.8
Roh, T.Y.9
Watford, W.T.10
Schones, D.E.11
Peng, W.12
Sun, H.W.13
Paul, W.E.14
O'shea, J.J.15
Zhao, K.16
-
24
-
-
79952113870
-
Critical role for IL-21 in both primary and memory anti-viral CD8+ T-cell responses
-
Barker BR, Gladstone MN, Gillard GO, Panas MW, Letvin NL. Critical role for IL-21 in both primary and memory anti-viral CD8+ T-cell responses. Eur J Immunol. 2010; 40:3085-3096.
-
(2010)
Eur J Immunol
, vol.40
, pp. 3085-3096
-
-
Barker, B.R.1
Gladstone, M.N.2
Gillard, G.O.3
Panas, M.W.4
Letvin, N.L.5
-
25
-
-
67649217469
-
IL-21 is required to control chronic viral infection
-
Elsaesser H, Sauer K, Brooks DG. IL-21 is required to control chronic viral infection. Science.2009; 324:1569-1572.
-
(2009)
Science
, vol.324
, pp. 1569-1572
-
-
Elsaesser, H.1
Sauer, K.2
Brooks, D.G.3
-
26
-
-
67649203681
-
A vital role for interleukin-21 in the control of a chronic viral infection
-
Yi JS, Du M, Zajac AJ. A vital role for interleukin-21 in the control of a chronic viral infection. Science. 2009; 324:1572-1576.
-
(2009)
Science
, vol.324
, pp. 1572-1576
-
-
Yi, J.S.1
Du, M.2
Zajac, A.J.3
-
27
-
-
67649234772
-
IL-21R on T cells is critical for sustained functionality and control of chronic viral infection
-
Fróhlich A, Kisielow J, Schmitz I, Freigang S, Shamshiev AT, Weber J Marsland BJ, Oxenius A, Kopf M. IL-21R on T cells is critical for sustained functionality and control of chronic viral infection. Science.2009; 324:1576-1580.
-
(2009)
Science
, vol.324
, pp. 1576-1580
-
-
Fróhlich, A.1
Kisielow, J.2
Schmitz, I.3
Freigang, S.4
Shamshiev, A.T.5
Weber, J.6
Marsland, B.J.7
Oxenius, A.8
Kopf, M.9
-
28
-
-
3543141247
-
Different contribution of EBV and CMV infections in very long-term carriers to age-related alterations of CD8+ T cells
-
Vescovini R, Telera A, Fagnoni FF, Biasini C, Medici MC, Valcavi P Biasini C, Medici MC, Valcavi P, di Pede P, Lucchini G, Zanlari L, Passeri G, Zanni F, Chezzi C, Franceschi C, Sansoni P. Different contribution of EBV and CMV infections in very long-term carriers to age-related alterations of CD8+ T cells. Exp. Gerontol.2004; 39:1233-1243.
-
(2004)
Exp. Gerontol
, vol.39
, pp. 1233-1243
-
-
Vescovini, R.1
Telera, A.2
Fagnoni, F.F.3
Biasini, C.4
Medici, M.C.5
Valcavi, P.6
Biasini, C.7
Medici, M.C.8
Valcavi, P.9
di Pede, P.10
Lucchini, G.11
Zanlari, L.12
Passeri, G.13
Zanni, F.14
Chezzi, C.15
Franceschi, C.16
Sansoni, P.17
-
29
-
-
32044433093
-
Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly
-
Hadrup SR, Strindhall J, Kollgaard T, Seremet T, Johansson B, Pawelec G thor Straten P, Wikby A. Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly. J Immunol. 2006; 176:2645-2653.
-
(2006)
J Immunol
, vol.176
, pp. 2645-2653
-
-
Hadrup, S.R.1
Strindhall, J.2
Kollgaard, T.3
Seremet, T.4
Johansson, B.5
Straten, P.P.G.t.6
Wikby, A.7
-
30
-
-
60549096353
-
Cytomegalovirus and human immunosenescence
-
Pawelec G, Derhovanessian E, Larbi A, Strindhall J, Wikby A. Cytomegalovirus and human immunosenescence. Rev Med Virol. 2009; 19:47-56.
-
(2009)
Rev Med Virol
, vol.19
, pp. 47-56
-
-
Pawelec, G.1
Derhovanessian, E.2
Larbi, A.3
Strindhall, J.4
Wikby, A.5
-
31
-
-
84866145898
-
Cytomegalovirus infection impairs immune responses and accentuates T-cell pool changes observed in mice with aging
-
Cicin-Sain L, Brien JD, Uhrlaub JL, Drabig A, Marandu TF, Nikolich-Zugich J. Cytomegalovirus infection impairs immune responses and accentuates T-cell pool changes observed in mice with aging. PLoS Pathog. 2012;8(8):e1002849.
-
(2012)
PLoS Pathog
, vol.8
, Issue.8
-
-
Cicin-Sain, L.1
Brien, J.D.2
Uhrlaub, J.L.3
Drabig, A.4
Marandu, T.F.5
Nikolich-Zugich, J.6
-
32
-
-
78149444089
-
Human dendritic cells activated via dectin-1 are efficient at priming Th17, cytotoxic CD8 T and B cell responses
-
Agrawal S, Gupta S, Agrawal A. Human dendritic cells activated via dectin-1 are efficient at priming Th17, cytotoxic CD8 T and B cell responses. PLoS One. 2010; 5(10):e13418.
-
(2010)
PLoS One
, vol.5
, Issue.10
-
-
Agrawal, S.1
Gupta, S.2
Agrawal, A.3
-
33
-
-
15844396183
-
Requirement for STAT4 in interleukin-12-mediated responses of natural killer and T cells
-
Thierfelder WE, van Deursen JM, Yamamoto K, Tripp RA, Sarawar SR, Carson RT, Sangster MY, Vignali DA, Doherty PC, Grosveld GC, Ihle JN. Requirement for STAT4 in interleukin-12-mediated responses of natural killer and T cells. Nature.1996; 382:171-174.
-
(1996)
Nature
, vol.382
, pp. 171-174
-
-
Thierfelder, W.E.1
van Deursen, J.M.2
Yamamoto, K.3
Tripp, R.A.4
Sarawar, S.R.5
Carson, R.T.6
Sangster, M.Y.7
Vignali, D.A.8
Doherty, P.C.9
Grosveld, G.C.10
Ihle, J.N.11
-
35
-
-
34547232503
-
IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells
-
Korn T, Bettelli E, Gao W, Awasthi A, Jager A, Strom TB, Oukka M, Kuchroo VK. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature. 2007; 448:484-487.
-
(2007)
Nature
, vol.448
, pp. 484-487
-
-
Korn, T.1
Bettelli, E.2
Gao, W.3
Awasthi, A.4
Jager, A.5
Strom, T.B.6
Oukka, M.7
Kuchroo, V.K.8
-
36
-
-
84863133298
-
IL-21 Promotes the Pathologic Immune Response to Pneumovirus Infection
-
2012 Jan 11
-
Spolski R, Wang L, Wan CK, Bonville CA, Domachowske JB, Kim HP, Yu Z, Leonard WJ. IL-21 Promotes the Pathologic Immune Response to Pneumovirus Infection. J Immunol. 2012 Jan 11.
-
J Immunol
-
-
Spolski, R.1
Wang, L.2
Wan, C.K.3
Bonville, C.A.4
Domachowske, J.B.5
Kim, H.P.6
Yu, Z.7
Leonard, W.J.8
-
37
-
-
34249775503
-
Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway
-
Agrawal A, Agrawal S, Cao JN, Su H, Osann K, Gupta S. Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway. J Immunol.2007; 178: 6912-6922.
-
(2007)
J Immunol
, vol.178
, pp. 6912-6922
-
-
Agrawal, A.1
Agrawal, S.2
Cao, J.N.3
Su, H.4
Osann, K.5
Gupta, S.6
-
38
-
-
77953645579
-
Rapamycin and quasi-programmed aging: four years later
-
Blagosklonny MV. Rapamycin and quasi-programmed aging: four years later. Cell Cycle. 2010;9:1859-1862.
-
(2010)
Cell Cycle
, vol.9
, pp. 1859-1862
-
-
Blagosklonny, M.V.1
|