-
1
-
-
80053893349
-
Trillion-dollar brain drain
-
Smith, K. (2011) Trillion-dollar brain drain Nature 478, 15
-
(2011)
Nature
, vol.478
, pp. 15
-
-
Smith, K.1
-
2
-
-
0022448068
-
Citalopram: Clinical effect profile in comparison with clomipramine. a controlled multicenter study
-
Danish University Antidepressant Group
-
Danish University Antidepressant Group (1986) Citalopram: Clinical effect profile in comparison with clomipramine. a controlled multicenter study Psychopharmacology (Berlin, Ger.) 90, 131-138
-
(1986)
Psychopharmacology (Berlin, Ger.)
, vol.90
, pp. 131-138
-
-
-
3
-
-
0025217229
-
Paroxetine: A selective serotonin reuptake inhibitor showing better tolerance, but weaker antidepressant effect than clomipramine in a controlled multicenter study
-
Danish University Antidepressant Group
-
Danish University Antidepressant Group (1990) Paroxetine: A selective serotonin reuptake inhibitor showing better tolerance, but weaker antidepressant effect than clomipramine in a controlled multicenter study J. Affective Disord. 18, 289-299
-
(1990)
J. Affective Disord.
, vol.18
, pp. 289-299
-
-
-
4
-
-
0028004358
-
How long to onset of antidepressant action: A m eta-analysis of patients treated with fluoxetine or placebo
-
Tollefson, G. D. and Holman, S. L. (1994) How long to onset of antidepressant action: A meta-analysis of patients treated with fluoxetine or placebo Int. Clin. Psychopharmacol. 9, 245-250 (Pubitemid 24374885)
-
(1994)
International Clinical Psychopharmacology
, vol.9
, Issue.4
, pp. 245-250
-
-
Tollefson, G.D.1
Holman, S.L.2
-
5
-
-
0035111499
-
Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors
-
DOI 10.1192/bjp.178.3.234
-
Thase, M. E., Entsuah, A. R., and Rudolph, R. L. (2001) Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors Br. J. Psychiatry 178, 234-241 (Pubitemid 32183606)
-
(2001)
British Journal of Psychiatry
, vol.178
, Issue.MARCH.
, pp. 234-241
-
-
Thase, M.E.1
Entsuah, A.R.2
Rudolph, R.L.3
-
6
-
-
33645099460
-
Medication augmentation after the failure of SSRIs for depression
-
Trivedi, M. H., Fava, M., Wisniewski, S. R., Thase, M. E., Quitkin, F., Warden, D., Ritz, L., Nierenberg, A. A., Lebowitz, B. D., Biggs, M. M., Luther, J. F., Shores-Wilson, K., and Rush, A. J. (2006) Medication augmentation after the failure of SSRIs for depression N. Engl. J. Med. 354, 1243-52
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 1243-1252
-
-
Trivedi, M.H.1
Fava, M.2
Wisniewski, S.R.3
Thase, M.E.4
Quitkin, F.5
Warden, D.6
Ritz, L.7
Nierenberg, A.A.8
Lebowitz, B.D.9
Biggs, M.M.10
Luther, J.F.11
Shores-Wilson, K.12
Rush, A.J.13
-
7
-
-
34948858402
-
Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial
-
DOI 10.1038/nm1632, PII NM1632
-
Patil, S. T., Zhang, L., Martenyi, F., Lowe, S. L., Jackson, K. A., Andreev, B. V., Avedisova, A. S., Bardenstein, L. M., Gurovich, I. Y., Morozova, M. A., Mosolov, S. N., Neznanov, N. G., Reznik, A. M., Smulevich, A. B., Tochilov, V. A., Johnson, B. G., Monn, J. A., and Schoepp, D. D. (2007) Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized phase II clinical trial Nat. Med. 13, 1102-1107 (Pubitemid 47517511)
-
(2007)
Nature Medicine
, vol.13
, Issue.9
, pp. 1102-1107
-
-
Patil, S.T.1
Zhang, L.2
Martenyi, F.3
Lowe, S.L.4
Jackson, K.A.5
Andreev, B.V.6
Avedisova, A.S.7
Bardenstein, L.M.8
Gurovich, I.Y.9
Morozova, M.A.10
Mosolov, S.N.11
Neznanov, N.G.12
Reznik, A.M.13
Smulevich, A.B.14
Tochilov, V.A.15
Johnson, B.G.16
Monn, J.A.17
Schoepp, D.D.18
-
8
-
-
33746896935
-
A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression
-
DOI 10.1001/archpsyc.63.8.856
-
Zarate, C. A., Jr., Singh, J. B., Carlson, P. J., Brutsche, N. E., Ameli, R., Luckenbaugh, D. A., Charney, D. S., and Manji, H. K (2006) A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression Arch. Gen. Psychiatry 63, 856-864 (Pubitemid 44188478)
-
(2006)
Archives of General Psychiatry
, vol.63
, Issue.8
, pp. 856-864
-
-
Zarate Jr., C.A.1
Singh, J.B.2
Carlson, P.J.3
Brutsche, N.E.4
Ameli, R.5
Luckenbaugh, D.A.6
Charney, D.S.7
Manji, H.K.8
-
10
-
-
0035336925
-
How does pindolol improve antidepressant action?
-
DOI 10.1016/S0165-6147(00)01682-5, PII S0165614700016825
-
Artigas, F., Celada, P., Laruelle, M., and Adell, A. (2001) How does pindolol improve antidepressant action? Trends Pharmacol. Sci. 22, 224-228 (Pubitemid 32411522)
-
(2001)
Trends in Pharmacological Sciences
, vol.22
, Issue.5
, pp. 224-228
-
-
Artigas, F.1
Celada, P.2
Laruelle, M.3
Adell, A.4
-
12
-
-
84867314101
-
Preclinical and clinical characterization of the selective serotonin-1A receptor antagonist DU-125530 for antidepressant treatment
-
Epub. PMID: 22050051
-
Scorza, M. C., Llado-Pelfort, L., Oller, S., Cortes, R., Puigdemont, D., Portella, M. J., Perez-Egea, R., Alvarez, E., Celada, P., Perez, V., and Artigas, F (2012). Preclinical and clinical characterization of the selective serotonin-1A receptor antagonist DU-125530 for antidepressant treatment. Br. J. Pharmacol. Epub. PMID: 22050051
-
(2012)
Br. J. Pharmacol.
-
-
Scorza, M.C.1
Llado-Pelfort, L.2
Oller, S.3
Cortes, R.4
Puigdemont, D.5
Portella, M.J.6
Perez-Egea, R.7
Alvarez, E.8
Celada, P.9
Perez, V.10
Artigas, F.11
-
13
-
-
84861447563
-
1A autoreceptors
-
1A autoreceptors Mol. Psychiatry 17, 612-623
-
(2012)
Mol. Psychiatry
, vol.17
, pp. 612-623
-
-
Bortolozzi, A.1
Castane, A.2
Semakova, J.3
Santana, N.4
Alvarado, G.5
Cortes, R.6
Ferres-Coy, A.7
Fernandez, G.8
Carmona, M.C.9
Toth, M.10
Perales, J.C.11
Montefeltro, A.12
Artigas, F.13
-
15
-
-
77954097572
-
Preferential in vivo action of F15599, a novel 5-HT(1A) receptor agonist, at postsynaptic 5-HT(1A) receptors
-
Lladó-Pelfort, L., Assié, M. B., Newman-Tancredi, A., Artigas, F., and Celada, P. (2010) Preferential in vivo action of F15599, a novel 5-HT(1A) receptor agonist, at postsynaptic 5-HT(1A) receptors Br. J. Pharmacol. 160, 1929-1940
-
(2010)
Br. J. Pharmacol.
, vol.160
, pp. 1929-1940
-
-
Lladó-Pelfort, L.1
Assié, M.B.2
Newman-Tancredi, A.3
Artigas, F.4
Celada, P.5
-
16
-
-
84856211754
-
5-HT(2B) receptors are required for serotonin-selective antidepressant actions
-
Diaz, S. L., Doly, S., Narboux-Neme, N., Fernandez, S., Mazot, P., Banas, S. M., Boutourlinsky, K., Moutkine, I., Belmer, A., Roumier, A., and Maroteaux, L. (2012) 5-HT(2B) receptors are required for serotonin-selective antidepressant actions Mol. Psychiatry 17, 154-163
-
(2012)
Mol. Psychiatry
, vol.17
, pp. 154-163
-
-
Diaz, S.L.1
Doly, S.2
Narboux-Neme, N.3
Fernandez, S.4
Mazot, P.5
Banas, S.M.6
Boutourlinsky, K.7
Moutkine, I.8
Belmer, A.9
Roumier, A.10
Maroteaux, L.11
-
17
-
-
34548246547
-
4) Receptor Agonists Are Putative Antidepressants with a Rapid Onset of Action
-
DOI 10.1016/j.neuron.2007.07.041, PII S0896627307006186
-
Lucas, G., Rymar, V. V., Du, J., Mnie-Filali, O., Bisgaard, C., Manta, S., Lambas-Senas, L., Wiborg, O., Haddjeri, N., Pineyro, G., Sadikot, A. F., and Debonnel, G. (2007) Serotonin(4) (5-HT(4)) receptor agonists are putative antidepressants with a rapid onset of action Neuron 55, 712-725 (Pubitemid 47334877)
-
(2007)
Neuron
, vol.55
, Issue.5
, pp. 712-725
-
-
Lucas, G.1
Rymar, V.V.2
Du, J.3
Mnie-Filali, O.4
Bisgaard, C.5
Manta, S.6
Lambas-Senas, L.7
Wiborg, O.8
Haddjeri, N.9
Pineyro, G.10
Sadikot, A.F.11
Debonnel, G.12
-
18
-
-
34047183030
-
6 receptor antagonist SB-399885 in animal models of anxiety and depression
-
DOI 10.1016/j.neuropharm.2007.01.007, PII S0028390807000111
-
Wesolowska, A. and Nikiforuk, A. (2007) Effects of the brain-penetrant and selective 5-HT6 receptor antagonist SB-399885 in animal models of anxiety and depression Neuropharmacology 52, 1274-1283 (Pubitemid 46527703)
-
(2007)
Neuropharmacology
, vol.52
, Issue.5
, pp. 1274-1283
-
-
Wesolowska, A.1
Nikiforuk, A.2
-
19
-
-
34247270861
-
7 receptors enhances 5-HT transmission, antidepressant-like behavior, and rapid eye movement sleep suppression induced by citalopram in rodents
-
DOI 10.1124/jpet.107.119404
-
7 receptors enhances 5-HT transmission, antidepressant-like behavior, and rapid eye movement sleep suppression induced by citalopram in rodents J. Pharmacol. Exp. Ther. 321, 690-698 (Pubitemid 46624521)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.321
, Issue.2
, pp. 690-698
-
-
Bonaventure, P.1
Kelly, L.2
Aluisio, L.3
Shelton, J.4
Lord, B.5
Galici, R.6
Miller, K.7
Atack, J.8
Lovenberg, T.W.9
Dugovic, C.10
-
20
-
-
0036720479
-
1A receptor partial agonist
-
DOI 10.1124/jpet.102.034280
-
Page, M. E., Cryan, J. F., Sullivan, A., Dalvi, A., Saucy, B., Manning, D. R., and Lucki, I. (2002) Behavioral and neurochemical effects of 5-(4-[4-(5-cyano-3-indolyl)-butyl)-butyl]-1-piperazinyl)-benzofuran-2- carboxamide (EMD 68843): A combined selective inhibitor of serotonin reuptake and 5-hydroxytryptamine(1A) receptor partial agonist J. Pharmacol. Exp. Ther. 302, 1220-1227 (Pubitemid 34920246)
-
(2002)
Journal of Pharmacology and Experimental Therapeutics
, vol.302
, Issue.3
, pp. 1220-1227
-
-
Page, M.E.1
Cryan, J.F.2
Sullivan, A.3
Dalvi, A.4
Saucy, B.5
Manning, D.R.6
Lucki, I.7
-
21
-
-
84863403855
-
Pharmacological effects of Lu AA21004: A novel multimodal compound for the treatment of major depressive disorder
-
Mork, A., Pehrson, A., Brennum, L. T., Nielsen, S. M., Zhong, H., Lassen, A. B., Miller, S., Westrich, L., Boyle, N. J., Sanchez, C., Fischer, C. W., Liebenberg, N., Wegener, G., Bundgaard, C., Hogg, S., Bang-Andersen, B., and Stensbol, T. B. (2012) Pharmacological effects of Lu AA21004: a novel multimodal compound for the treatment of major depressive disorder J. Pharmacol. Exp. Ther. 340, 666-675
-
(2012)
J. Pharmacol. Exp. Ther.
, vol.340
, pp. 666-675
-
-
Mork, A.1
Pehrson, A.2
Brennum, L.T.3
Nielsen, S.M.4
Zhong, H.5
Lassen, A.B.6
Miller, S.7
Westrich, L.8
Boyle, N.J.9
Sanchez, C.10
Fischer, C.W.11
Liebenberg, N.12
Wegener, G.13
Bundgaard, C.14
Hogg, S.15
Bang-Andersen, B.16
Stensbol, T.B.17
|