Investigating the structural dynamics of α-1,4-galactosyltransferase C from Neisseria meningitidis by nuclear magnetic resonance spectroscopy

Biochemistry

Volumn 52, Issue 2, 2013, Pages 320-332

  Chan, Patrick H W ^a   Cheung, Adrienne H ^a   Okon, Mark ^a   Chen, Hong Ming ^a   Withers, Stephen G ^a   McIntosh, Lawrence P ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; CONFORMATIONAL MOBILITY; CONFORMATIONAL STATE; ENZYMATIC MECHANISMS; GALACTOSYLATION; GLYCOSYL TRANSFERASE; GLYCOSYL-ENZYME INTERMEDIATE; LIPOOLIGOSACCHARIDES; MAGNETIZATION TRANSFER; METHYL-TROSY; NEISSERIA MENINGITIDIS; RELAXATION DISPERSION; SIDE-CHAINS; STRUCTURAL CHANGE; SUBSTRATE BINDING; TIME-SCALES; TRANSFER MECHANISMS;

AMINO ACIDS; ENZYMES; MAGNETIC RESONANCE SPECTROMETERS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SUGARS; TIME MEASUREMENT;

STRUCTURAL DYNAMICS;

ALPHA 1,4 GALACTOSYLTRANSFERASE C; BACTERIAL PROTEIN; GLYCOSYLTRANSFERASE; ISOLEUCINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING KINETICS; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; DISPERSION; ENZYME ACTIVE SITE; ENZYME SUBSTRATE; MOLECULAR DYNAMICS; MOTION; NEISSERIA MENINGITIDIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; TEMPERATURE;

CATALYTIC DOMAIN; GALACTOSYLTRANSFERASES; MODELS, MOLECULAR; NEISSERIA MENINGITIDIS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHENYLALANINE; POINT MUTATION; PROTEIN CONFORMATION;

NEISSERIA MENINGITIDIS;

EID: 84872539712     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi301317d     Document Type: Article

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