메뉴 건너뛰기




Volumn 170, Issue , 2012, Pages 42-50

Insight into estrogen receptor beta-beta and alpha-beta homo- and heterodimerization: A combined molecular dynamics and sequence analysis study

Author keywords

Estrogen receptor; Evolution; Homo and heterodimer; Loop dynamics; Molecular dynamics; Phylogeny

Indexed keywords

ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; HETERODIMER;

EID: 84872529288     PISSN: 03014622     EISSN: 18734200     Source Type: Journal    
DOI: 10.1016/j.bpc.2012.09.002     Document Type: Article
Times cited : (30)

References (31)
  • 9
    • 0033386954 scopus 로고    scopus 로고
    • Estrogen receptor β - A new dimension in estrogen mechanism of action
    • J-Ar. Gustafsson Estrogen receptor β - a new dimension in estrogen mechanism of action The Journal of Endocrinology 163 1999 379 383
    • (1999) The Journal of Endocrinology , vol.163 , pp. 379-383
    • Gustafsson, J.-Ar.1
  • 10
    • 33748743807 scopus 로고    scopus 로고
    • Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells
    • E.C. Chang, J. Frasor, B. Komm, and B.S. Katzenellenbogen Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells Endocrinology 147 2006 4831 4842
    • (2006) Endocrinology , vol.147 , pp. 4831-4842
    • Chang, E.C.1    Frasor, J.2    Komm, B.3    Katzenellenbogen, B.S.4
  • 11
    • 27144524273 scopus 로고    scopus 로고
    • Estrogen receptors alpha (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11
    • L.A. Helguero, M.H. Faulds, J.A. Gustafsson, and L.A. Haldosen Estrogen receptors alpha (ERalpha) and beta (ERbeta) differentially regulate proliferation and apoptosis of the normal murine mammary epithelial cell line HC11 Oncogene 24 2005 6605 6616
    • (2005) Oncogene , vol.24 , pp. 6605-6616
    • Helguero, L.A.1    Faulds, M.H.2    Gustafsson, J.A.3    Haldosen, L.A.4
  • 12
    • 0034641862 scopus 로고    scopus 로고
    • Estrogen receptor beta acts as a dominant regulator of estrogen signaling
    • K. Pettersson, F. Delaunay, and J.A. Gustafsson Estrogen receptor beta acts as a dominant regulator of estrogen signaling Oncogene 19 2000 4970 4978
    • (2000) Oncogene , vol.19 , pp. 4970-4978
    • Pettersson, K.1    Delaunay, F.2    Gustafsson, J.A.3
  • 13
    • 84863066879 scopus 로고    scopus 로고
    • Identification of estrogen receptor dimer selective ligands reveals growth-inhibitory effects on cells that co-express ERa and ERb
    • 10.1371/journal.pone.0030993
    • E. Powell, E. Shanle, A. Brinkman, J. Li, S. Keles, K.B. Wisinski, W. Huang, and W. Xuet Identification of estrogen receptor dimer selective ligands reveals growth-inhibitory effects on cells that co-express ERa and ERb PLoS One 7 2012 e30993 10.1371/journal.pone.0030993
    • (2012) PLoS One , vol.7 , pp. 30993
    • Powell, E.1    Shanle, E.2    Brinkman, A.3    Li, J.4    Keles, S.5    Wisinski, K.B.6    Huang, W.7    Xuet, W.8
  • 15
    • 28744458215 scopus 로고    scopus 로고
    • Clinical significance of estrogen receptor beta in breast cancer
    • S. Saji, M. Hirose, and M. Toi Clinical significance of estrogen receptor beta in breast cancer Cancer Chemotherapy and Pharmacology 56 2005 21 26
    • (2005) Cancer Chemotherapy and Pharmacology , vol.56 , pp. 21-26
    • Saji, S.1    Hirose, M.2    Toi, M.3
  • 16
    • 0037314762 scopus 로고    scopus 로고
    • Estrogen receptor (ER)-beta reduces ERalpha-regulated gene transcription, supporting a "ying yang" relationship between ERalpha and ERbeta in mice
    • M.K. Lindberg, S. Moverare, S. Skrtic, H. Gao, K. Dahlman-Wright, J.A. Gustafsson, and C. Ohlsson Estrogen receptor (ER)-beta reduces ERalpha-regulated gene transcription, supporting a "ying yang" relationship between ERalpha and ERbeta in mice Molecular Endocrinology 17 2003 203 208
    • (2003) Molecular Endocrinology , vol.17 , pp. 203-208
    • Lindberg, M.K.1    Moverare, S.2    Skrtic, S.3    Gao, H.4    Dahlman-Wright, K.5    Gustafsson, J.A.6    Ohlsson, C.7
  • 17
    • 0030747070 scopus 로고    scopus 로고
    • Mouse estrogen receptor beta forms estrogen response element-binding heterodimers with estrogen receptor alpha
    • K. Pettersson, K. Grandien, G.G. Kuiper, and J.A. Gustafsson Mouse estrogen receptor beta forms estrogen response element-binding heterodimers with estrogen receptor alpha Molecular Endocrinology 11 1997 1486 1496
    • (1997) Molecular Endocrinology , vol.11 , pp. 1486-1496
    • Pettersson, K.1    Grandien, K.2    Kuiper, G.G.3    Gustafsson, J.A.4
  • 18
    • 0033053616 scopus 로고    scopus 로고
    • Dominant activity of activation function 1 (AF-1) and differential stoichiometric requirements for AF-1 and - 2 in the estrogen receptor alpha-beta heterodimeric complex
    • G.B. Tremblay, A. Tremblay, F. Labrie, and V. Giguere Dominant activity of activation function 1 (AF-1) and differential stoichiometric requirements for AF-1 and - 2 in the estrogen receptor alpha-beta heterodimeric complex Molecular and Cellular Biology 19 1999 1919 1927
    • (1999) Molecular and Cellular Biology , vol.19 , pp. 1919-1927
    • Tremblay, G.B.1    Tremblay, A.2    Labrie, F.3    Giguere, V.4
  • 19
    • 84869501807 scopus 로고    scopus 로고
    • In silico design of peptidic inhibitors targeting Estrogen Receptor alpha dimer interface
    • 10.1007/s11030-012-9378-x
    • S. Chakraborty, S. Cole, N. Rader, C. King, R.V. Rajnarayanan, and P.K. Biswas In silico design of peptidic inhibitors targeting Estrogen Receptor alpha dimer interface Molecular Diversity 2012 10.1007/s11030-012-9378-x
    • (2012) Molecular Diversity
    • Chakraborty, S.1    Cole, S.2    Rader, N.3    King, C.4    Rajnarayanan, R.V.5    Biswas, P.K.6
  • 20
    • 0027136282 scopus 로고
    • Comparative protein modelling by satisfaction of spatial restraints
    • A. Sali, and T.L. Blundell Comparative protein modelling by satisfaction of spatial restraints Journal of Molecular Biology 234 1993 779 815
    • (1993) Journal of Molecular Biology , vol.234 , pp. 779-815
    • Sali, A.1    Blundell, T.L.2
  • 22
    • 0035789518 scopus 로고    scopus 로고
    • GROMACS 3.0 a package for molecular simulation and trajectory analysis
    • E. Lindahl, B. Hess, and D.V.D. Spoel GROMACS 3.0 a package for molecular simulation and trajectory analysis Journal of Molecular Modelling 7 2001 306 317
    • (2001) Journal of Molecular Modelling , vol.7 , pp. 306-317
    • Lindahl, E.1    Hess, B.2    Spoel, D.V.D.3
  • 23
    • 33645941402 scopus 로고
    • Development and testing of the OPLS all-atom force field on conformational energetic and properties of organic liquids
    • W.L. Jorgensen, and T. Rives Development and testing of the OPLS all-atom force field on conformational energetic and properties of organic liquids Journal of the American Chemical Society 110 1988 1657 1666
    • (1988) Journal of the American Chemical Society , vol.110 , pp. 1657-1666
    • Jorgensen, W.L.1    Rives, T.2
  • 25
    • 0020997912 scopus 로고
    • Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features
    • W. Kabsch, and C. Sander Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features Biopolymers 22 1983 2577 2637
    • (1983) Biopolymers , vol.22 , pp. 2577-2637
    • Kabsch, W.1    Sander, C.2
  • 26
    • 66349094681 scopus 로고    scopus 로고
    • Identification of computational hotspots in protein interfaces: Combining solvent accessibility and inter-residue potential improves the accuracy
    • N. Tuncbag, A. Gursoy, and O. Keskin Identification of computational hotspots in protein interfaces: combining solvent accessibility and inter-residue potential improves the accuracy Bioinformatics 25 2009 1513 1520
    • (2009) Bioinformatics , vol.25 , pp. 1513-1520
    • Tuncbag, N.1    Gursoy, A.2    Keskin, O.3
  • 27
    • 33745634395 scopus 로고    scopus 로고
    • Cd-hit: A fast program for clustering and comparing large sets of protein or nucleotide sequences
    • W. Li, and A. Godzik Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences Bioinformatics 22 2006 1658 1659
    • (2006) Bioinformatics , vol.22 , pp. 1658-1659
    • Li, W.1    Godzik, A.2
  • 28
    • 3042666256 scopus 로고    scopus 로고
    • MUSCLE: Multiple sequence alignment with high accuracy and high throughput
    • R.C. Edgar MUSCLE: multiple sequence alignment with high accuracy and high throughput Nucleic Acids Research 32 2004 1792 1797
    • (2004) Nucleic Acids Research , vol.32 , pp. 1792-1797
    • Edgar, R.C.1
  • 29
    • 77950806408 scopus 로고    scopus 로고
    • New algorithms and methods to estimate maximum-likelihood phylogenies: Assessing the performance of PhyML 3.0
    • S. Guindon, J.F. Dufayard, V. Lefort, M. Anisimova, W. Hordijk, and O. Gascuel New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0 Systems Biology 59 2010 307 321
    • (2010) Systems Biology , vol.59 , pp. 307-321
    • Guindon, S.1    Dufayard, J.F.2    Lefort, V.3    Anisimova, M.4    Hordijk, W.5    Gascuel, O.6
  • 30
    • 33750314083 scopus 로고    scopus 로고
    • TreeDyn: Towards dynamic graphics and annotations for analyses of trees
    • F. Chevenet, C. Brun, A.L. Banuls, B. Jacq, and R. Chisten TreeDyn: towards dynamic graphics and annotations for analyses of trees BMC Bioinformatics 7 2006 439 447
    • (2006) BMC Bioinformatics , vol.7 , pp. 439-447
    • Chevenet, F.1    Brun, C.2    Banuls, A.L.3    Jacq, B.4    Chisten, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.