Potentiation of in vitro and in vivo antitumor efficacy of doxorubicin by cyclin-dependent kinase inhibitor P276-00 in human non-small cell lung cancer cells

BMC Cancer

Volumn 13, Issue , 2013, Pages

  Rathos, Maggie J ^a   Khanwalkar, Harshal ^a   Joshi, Kavita ^a   Manohar, Sonal M ^a   Joshi, Kalpana S ^a  

^a Piramal Enterprises Limited   (India)

Author keywords

Chemotherapy; Cyclin dependent kinase inhibitor; Doxorubicin; Non small cell lung cancer; P276 00

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLIN DEPENDENT KINASE 1; CYCLOOXYGENASE 2; DOXORUBICIN; P 276 00; PROPIDIUM IODIDE; PROTEIN BCL 2; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER CELL DESTRUCTION; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG POTENTIATION; DRUG RESEARCH; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG NON SMALL CELL CANCER; M PHASE CELL CYCLE CHECKPOINT; MOUSE; MULTIPLE CYCLE TREATMENT; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR XENOGRAFT; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CARCINOMA, NON-SMALL-CELL LUNG; CDC2 PROTEIN KINASE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLOOXYGENASE 2; DOXORUBICIN; DRUG SYNERGISM; FLAVONES; G2 PHASE CELL CYCLE CHECKPOINTS; HUMANS; LUNG NEOPLASMS; MICE; MICE, SCID; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84872520610     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-29     Document Type: Article

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