Antibody repertoire development in fetal and neonatal piglets. XVI. Influenza stimulates adaptive immunity, class switch and diversification of the IgG repertoire encoded by downstream Cγ genes

Immunology

Volumn 138, Issue 2, 2013, Pages 134-144

  Butler, John E ^a   Sun, Xiuzhu ^a   Wertz, Nancy ^a   Vincent, Amy L ^b   Zanella, Eraldo L ^c   Lager, Kelly M ^b  

^a UNIVERSITY OF IOWA   (United States)

^b NATIONAL ANIMAL DISEASE CENTER   (United States)

^c Campus Universitario do Bairro Sao Jose   (Brazil)

Author keywords

Antibody repertoire development; Class switch recombination; IgG subclasses; Swine influenza

Indexed keywords

ANTIGEN; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G3 ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; INTERLEUKIN 2 RECEPTOR GAMMA; TRINITROPHENYL;

ADAPTIVE IMMUNITY; AFFINITY CHROMATOGRAPHY; ANIMAL EXPERIMENT; ARTICLE; FEMALE; FETUS; GENETIC RECOMBINATION; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; INFLUENZA; INFLUENZA VIRUS; INNATE IMMUNITY; LUNG LAVAGE; LYMPH NODE; NEWBORN; NEWBORN PERIOD; NONHUMAN; PRIORITY JOURNAL; SWINE;

ADAPTIVE IMMUNITY; ANIMALS; ANIMALS, NEWBORN; ANTIBODIES, VIRAL; CELL LINE; DOGS; FETUS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INFLUENZA A VIRUS, H1N1 SUBTYPE; ORTHOMYXOVIRIDAE INFECTIONS; PEYER'S PATCHES; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; SWINE; SWINE DISEASES;

EID: 84872520139     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12018     Document Type: Article

References (46)

1. Butler JE, Sun J, Weber P, Francis D. Antibody repertoire development in fetal and neonatal piglets III. Colonization of the gastrointestinal tracts results in preferential diversification of the pre-immune mucosal B-cell repertoire. Immunology 2000; 100:119-30.
2. Butler JE, Weber P, Sinkora M, Baker D, Schoenherr A, Mayer B, Francis D. Antibody repertoire development in fetal and neonatal piglets VIII. Colonization is required for newborn piglets to make serum antibodies to T-dependent and type 2 T-independent antigens. J Immunol 2002; 169:6822-30.
3. Butler JE, Francis D, Freeling J, Weber P, Sun J, Krieg AM. Antibody repertoire development in fetal and neonatal piglets IX. Three PAMPs act synergistically to allow germfree piglets to respond to TI-2 and TD antigens. J Immunol 2005; 175:6772-85.
4. Cunnington PG, Naismith JD. Naturally occurring double-stranded RNA and immune responses III. Immunogenicity and antigenicity in animals. Immunology 1975; 29:1001-17.
5. Butler JE, Sinkora M. The isolator piglet: a model for studying the development of adaptive immunity. Immunol Res 2007; 39:33-51.
6. Butler JE, Sinkora M, Wertz N, Holtmeier W, Lemke CD. Development of the neonatal B- and T-cell repertoire in swine: implications for comparative and veterinary immunology. In: Haverson K, Bailey M, Charley B, guest eds. Mucosal Immunity in Domestic Animals. Vet Res 2006; 37: 417-441
7. Brambell FWR. The Transmission of Passive Immunity from Mother to Young. Amsterdam: North-Holland. Publ. Co, 1970
8. Butler JE. Immunoglobulins of the mammary secretions. In: Larson BL, Smith V, eds. Lactation, a Comprehensive Treatise. New York: Academic Press, 1974:217-55.
9. Butler JE, Sun J, Weber P, Ford SP, Rehakova Z, Sinkora J, Lager K. Antibody repertoire development in fetal and neonatal piglets IV. Switch recombination, primarily in fetal thymus occurs independent of environmental antigen and is only weakly associated with repertoire diversification. J Immunol 2001; 167:3239-49.
10. Butler JE, Wertz N. Antibody repertoire development in fetal and neonatal piglets XVII. IgG subclass transcription revisited with emphasis on new IgG3. J Immunol 2006; 177:5480-9.
11. Casali P, Schettino EW. Structure and function of natural antibodies. In: Potter M, Rose NR, eds. Immunology of Silicone. Berlin: Springer Verlag, 1996; 167-79.
12. Ochsenbein AF, Zinkernagel R. Natural antibodies and complement link innate and acquired immunity. Immunol Today 2000; 1:624-30.
13. Butler JE, Weber P, Wertz N. Antibody repertoire development in fetal and neonatal pigs XIII. "Hybrid VH genes" and the pre-immune repertoire revisited. J Immunol 2006; 177:5459-70.
14. Butler JE, Sun X-Z, Wertz N, Lager KM, Chaloner K, Urban J Jr, Nara P, Tobin G. Antibody repertoire development in fetal and neonatal piglets XXI. VH usage remains constant during development in fetal piglets and postnatally in pigs exposed to environmental antigen. Mol Immunol 2011; 49:483-94.
15. Butler JE, Lager KM, Splichal I et al. The piglet as a model for B cell and immune system development. Vet Immunol Immunopathol 2009; 128:147-70.
16. Lutz C, Ledermann B, Kosco-Vilbois MH, Ochsenbein AF, Zinkernagel RM, Kohler G, Brombacker F. IgD can largely substitute for loss of IgM function in B cells. Nature 1998; 393:797-801.
17. Eguchi-Ogawa T, Sun X-Z, Wertz N et al. Antibody repertoire development in fetal and neonatal piglets XI. The relationship of VDJ usage and the genomic organization of the variable heavy chain locus. J Immunol 2010; 184:3734-42.
18. Butler JE, Wertz N, Deschacht N, Kacskovics I. Porcine IgG: structure, genetics and evolution. Immunogenetics 2009; 61:209-30.
19. Kloep A, Wertz N, Mendicino M, Butler JE. Linkage haplotype for IgG and IgA subclass genes. Immunogenetics 2012; 64:469-473.
20. Gauger PC, Vincent AL, Loving CL, Lager KM, Janke BH, Kehrlie ME Jr, Roth JA. Enhanced pneumonia and disease in pigs vaccinated with an inactivated human-like (d-cluster) H1N2 vaccine and changed with pandemic 2009 H1N1 influenza virus. Vaccine 2011; 29:2712-9.
21. Ciacci-Zanella JR, Vincent AL, Prickett JR, Zimmerman SM, Zimmerman JJ. Detection of anti-influenza A nucleoprotein antibodies in pigs using a commercial influenza epitope-blocking enzyme-linked immunosorbent assay developed for avian species. J Vet Diagn Invest 2010; 22:3-9.
22. Peterman JH, Butler JE. Application of theoretical considerations to the analysis of ELISA data. Biotechniques 1989; 7:608-15.
23. Sun J, Butler JE. Molecular characteristics of VDJ transcripts from a newborn piglet. Immunology 1996; 88:331-9.
24. Butler JE, Weber P, Sinkora M, Sun J, Ford SJ, Christenson R. Antibody repertoire development in fetal and neonatal piglets II. Characterization of heavy chain CDR3 diversity in the developing fetus. J Immunol 2000; 165:6999-7011.
25. Klobasa F, Werhahn E, Butler JE. Regulation of humoral immunity in the piglet by immunoglobulins of maternal origin. Res Vet Sci 1981; 31:195-206.
26. Freund J. Some aspects of active immunization. Annu Rev Microbiol 1947; 1:291-308.
27. Johnson AG, Gaines S, Landy M. Studies on the O antigen of Salmonella typhosa V. Enhancement of antibody response to protein antigens by the purified lipopolysaccharide. J Exp Med 1956; 103:225-46.
28. Bachmann MF, Zinkernagel RM. Neutralizing antiviral B cell responses. Annu Rev Immunol 1997; 15:225-70.
29. Hunziker L, Recher M, Macpherson AJ, Ciurea A, Freigang S, Hengartner H, Zinkernagel RM. Hypergammaglobulinemia and autoantibody induction mechanisms in viral infection. Nat Immunol 2003; 4:343-9.
30. Lemke CD, Haynes JS, Spaete R, Adolphson D, Vorwald A, Lager K, Butler JE. Lymphoid hyperplasia resulting in immune dysregulation is caused by PRRSV infection in pigs. J Immunol 2004; 172:1916-25.
31. Bouvet JP, Dighiero G. From natural polyreactive autoantibodies to a la carte monoreactive antibodies to infectious agents: is it a small world after all. Infect Immun 1998; 66:1-4.
32. Baumgarth N, Tung JW, Herzenberg LA. Inherent specificities in natural antibodies: a key to immune defense against pathogen invasion. Semin Immunopathol 2005; 26:347-362.
33. Bernasconi NL, Traggial E, Lanzavecchia A. Maintenance of serological memory by polyclonal activation of human memory B cells. Science 2002; 298:2199-202.
34. Tortorella D, Gewurz BE, Furman MH, Schust DJ, Ploegh HL. Viral subversion of the immune system. Annu Rev Immunol 2000; 18:861-926.
35. Butler JE, Kiddy CA, Pierce CS, Rock CA. Quantitative changes associated with calving in the levels of bovine immunoglobulins in selected body fluids I. Changes in the levels of IgA, IgG1 and total protein. Can J Comp Med 1972; 36:235-42.
36. Butler JE, Richerson HB, Kopp WC, Suelzer MJ, Barfknecht C. The influence of muramyl dipeptide on secretory immunity. In: Kunkel H, Mestecky J, McGhee J, eds. The Secretory Immune System. New York: Academy of Science, 1983; 409:669-87
37. Gorin AB, Gould J. Immuoglobulin syntheses in the lung and caudal mediastinal lymph node of sheep. J Immunol 1979; 123:1339-42.
38. Butler JE, Wertz N, Sun X-Z, Lunney JK, Myyldermans S. Resolution of an immunodiagnostic dilemma: heavy chain chimeric antibodies for species in which plasmocytomas are unknown. Mol Immunol 2013; 53:140-8.
39. Willoughby JB, Willoughby WF. In vivo responses to inhaled proteins I. Quantitative analysis of antigen uptake, fate and immmunogenicity in a rabbit model system. J Immunol 1977; 119:2137-46.
40. Liu L M, MacPherson GG. Lymph-borne (veiled) dendritic cells can acquire and present intestinally administered antigens. Immunology 1991; 73:281-6.
41. Butler JE, Mateo K, Sun X-Z, Wertz N, Sinkora M, Harvey R, Francis DL. Antibody repertoire development in fetal and neonatal piglets XX. The ileal Peyer's patches are not a site of B cell lymphogenesis and are not required for systemic B cell proliferation and Ig synthesis. J Immunol 2011; 187:5141-9.
42. Doherty PC, Christensen JP. Accessing complexity: the dynamics of virus-specific T cell responses. Annu Rev Immunol 2000; 18:561-82.
43. + T cells. J Exp Med 1991; 174:875-80.
44. Stambas J, Huillineau C, Kedzierska K, Mintern JD, Doherty PC, La Gruta NL. Killer T cells in influenza. Pharmacol Ther 2008; 120:186-96.
45. Slifka MK, Antiia R, Whitemore JK, Ahmed R. Humoral immunity due to long-lived plasma cells. Immunity 1998; 8:363-72.
46. Couch RB, Kasel JA. Immunity to influenza in man. Annu Rev Microbiol 1983; 37:529-49.