-
1
-
-
0025298933
-
Critical analysis of the use of computer-Assisted transverse axial tomography to study human brain in aging and dementia of the Alzheimer type
-
DeCarli C, Kaye JA, Horwitz B, Rapoport SI (1990) Critical analysis of the use of computer-Assisted transverse axial tomography to study human brain in aging and dementia of the Alzheimer type. Neurology 40, 872-883
-
(1990)
Neurology
, vol.40
, pp. 872-883
-
-
DeCarli, C.1
Kaye, J.A.2
Horwitz, B.3
Rapoport, S.I.4
-
2
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82, 239-259
-
(1991)
Acta Neuropathol
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
3
-
-
0021145680
-
Alzheimer's disease: Cell-Specific pathology isolates the hippocampal formation
-
Hyman BT,Van HoesenGW, Damasio AR, Barnes CL (1984) Alzheimer's disease: Cell-Specific pathology isolates the hippocampal formation. Science 225, 1168-1170
-
(1984)
Science
, vol.225
, pp. 1168-1170
-
-
Hyman, B.T.1
Van Hoesen, G.W.2
Damasio, A.R.3
Barnes, C.L.4
-
4
-
-
84920237810
-
A new definition of Alzheimer's disease: A hippocampal dementia
-
Ball M, Fisman M, Hachinski V, Blume W, Fox A, Kral V (1985) A new definition of Alzheimer's disease: A hippocampal dementia. Lancet 1, 14-16
-
(1985)
Lancet
, vol.1
, pp. 14-16
-
-
Ball, M.1
Fisman, M.2
Hachinski, V.3
Blume, W.4
Fox, A.5
Kral, V.6
-
5
-
-
0028122463
-
Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease
-
West M, Coleman P, Flood D, Troncoso J (1994) Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease. Lancet 2, 769-772
-
(1994)
Lancet
, vol.2
, pp. 769-772
-
-
West, M.1
Coleman, P.2
Flood, D.3
Troncoso, J.4
-
6
-
-
0023757508
-
Quantitative NMR measurements of hippocampal atrophy in Alzheimer's disease
-
Seab JP, Jagust WJ,Wong STS, Roos MS, Reed BR, Budinger TF (1988) Quantitative NMR measurements of hippocampal atrophy in Alzheimer's disease. Magnc Reson Med 8, 200-208
-
(1988)
Magnc Reson Med
, vol.8
, pp. 200-208
-
-
Seab, J.P.1
Jagust, W.J.2
Wong, S.T.S.3
Roos, M.S.4
Reed, B.R.5
Budinger, T.F.6
-
7
-
-
0026058073
-
Quantification of magnetic resonance scans for hippocampal and parahippocampal atrophy in Alzheimer's disease
-
Kesslak JP, Nalcioglu O, Cotman CW (1991) Quantification of magnetic resonance scans for hippocampal and parahippocampal atrophy in Alzheimer's disease. Neurology 41, 51-54
-
(1991)
Neurology
, vol.41
, pp. 51-54
-
-
Kesslak, J.P.1
Nalcioglu, O.2
Cotman, C.W.3
-
8
-
-
0026597219
-
MRbased hippocampal volumetry in the diagnosis of Alzheimer's disease
-
Jack CR, Petersen RC, O'Brien PC, Tangalos EG (1992) MRbased hippocampal volumetry in the diagnosis of Alzheimer's disease. Neurology 42, 183-188
-
(1992)
Neurology
, vol.42
, pp. 183-188
-
-
Jack, C.R.1
Petersen, R.C.2
O'Brien, P.C.3
Tangalos, E.G.4
-
9
-
-
0027312983
-
Temporal lobe regions on magnetic resonance imaging identify patients with early Alzheimer's disease
-
Killiany RJ, Moss MB, Albert MS, Sandor T, Tieman J, Jolesz F (1993) Temporal lobe regions on magnetic resonance imaging identify patients with early Alzheimer's disease. Arch Neurol 50, 949-954
-
(1993)
Arch Neurol
, vol.50
, pp. 949-954
-
-
Killiany, R.J.1
Moss, M.B.2
Albert, M.S.3
Sandor, T.4
Tieman, J.5
Jolesz, F.6
-
10
-
-
0028332872
-
Amygdalohippocampal MR volume measurements in the early stages of Alzheimer disease
-
Leh'ericy S, Baulac M, Chiras J, Pi'erot L, Martin N, Pillon B, Deweer B, Dubois B, Marsault C (1994) Amygdalohippocampal MR volume measurements in the early stages of Alzheimer disease. AJNR Am J Neuroradiol 15, 929-937
-
(1994)
AJNR Am J Neuroradiol
, vol.15
, pp. 929-937
-
-
Leh'ericy, S.1
Baulac, M.2
Chiras, J.3
Pi'erot, L.4
Martin, N.5
Pillon, B.6
Deweer, B.7
Dubois, B.8
Marsault, C.9
-
11
-
-
0028900456
-
Volumes of hippocampus, amygdala and frontal lobes in the MRI-based diagnosis of early Alzheimer's disease: Correlation with memory functions
-
Laakso MP, Soininen H, Partanen K, Helkala EL, Hartikainen P, Vainio P, Hallikainen M, Hánninen T, Riekkinen PJ (1995) Volumes of hippocampus, amygdala and frontal lobes in the MRI-based diagnosis of early Alzheimer's disease: Correlation with memory functions. J Neural Transm Park Dis Dement Sect 9, 73-86
-
(1995)
J Neural Transm Park Dis Dement Sect
, vol.9
, pp. 73-86
-
-
Laakso, M.P.1
Soininen, H.2
Partanen, K.3
Helkala, E.L.4
Hartikainen, P.5
Vainio, P.6
Hallikainen, M.7
Hánninen, T.8
Riekkinen, P.J.9
-
12
-
-
56349116391
-
Molecular genetics of Alzheimer's disease: An update
-
Brouwers N, Sleegers K, Van Broeckhoven C (2008) Molecular genetics of Alzheimer's disease: An update. Ann Med 40, 562-583
-
(2008)
Ann Med
, vol.40
, pp. 562-583
-
-
Brouwers, N.1
Sleegers, K.2
Van Broeckhoven, C.3
-
13
-
-
78649232442
-
Genetics of Alzheimer's disease
-
Bekris LM, Yu C-E, Bird T, Tsuang D (2010) Genetics of Alzheimer's disease. J Geriatr Psychiatry Neurol 23, 213-227
-
(2010)
J Geriatr Psychiatry Neurol
, vol.23
, pp. 213-227
-
-
Bekris, L.M.1
Yu, C.-E.2
Bird, T.3
Tsuang, D.4
-
14
-
-
0030499848
-
Clinical features of sporadic and familial Alzheimer's disease
-
Rossor MN, Fox NC, Freeborough PA, Harvey RJ (1996) Clinical features of sporadic and familial Alzheimer's disease. Neurodegeneration 5, 393-397
-
(1996)
Neurodegeneration
, vol.5
, pp. 393-397
-
-
Rossor, M.N.1
Fox, N.C.2
Freeborough, P.A.3
Harvey, R.J.4
-
15
-
-
0030451306
-
Presymptomatic hippocampal atrophy in Alzheimer's disease A longitudinal MRI study
-
Fox NC, Warrington EK, Freeborough PA, Hartikainen P, Kennedy AM (1996) Presymptomatic hippocampal atrophy in Alzheimer's disease A longitudinal MRI study. Brain 119 (Pt 6), 2001-2007
-
(1996)
Brain
, vol.119
, Issue.PART 6
, pp. 2001-2007
-
-
Fox, N.C.1
Warrington, E.K.2
Freeborough, P.A.3
Hartikainen, P.4
Kennedy, A.M.5
-
16
-
-
0029969338
-
Atrophy of the hippocampal formation in early familial Alzheimer's disease A longitudinal MRI study of at-risk members of a family with an amyloid precursor protein 717Val-Gly mutation
-
Fox NC, Warrington EK, Stevens JM, Rossor MN (1996) Atrophy of the hippocampal formation in early familial Alzheimer's disease. A longitudinal MRI study of at-risk members of a family with an amyloid precursor protein 717Val-Gly mutation. Ann N Y Acad Sci 777, 226-232
-
(1996)
Ann N Y Acad Sci
, vol.777
, pp. 226-232
-
-
Fox, N.C.1
Warrington, E.K.2
Stevens, J.M.3
Rossor, M.N.4
-
17
-
-
0029802526
-
Accurate registration of serial 3D MR brain images and its application to visualizing change in neurodegenerative disorders
-
Freeborough PA, Woods RP, Fox N (1996) Accurate registration of serial 3D MR brain images and its application to visualizing change in neurodegenerative disorders. J Comp Asst Tomogr 20, 1012-1022
-
(1996)
J Comp Asst Tomogr
, vol.20
, pp. 1012-1022
-
-
Freeborough, P.A.1
Woods, R.P.2
Fox, N.3
-
18
-
-
0038375823
-
A longitudinal study of brain volume changes in normal aging using serial registered magnetic resonance imaging
-
Scahill RI, Frost C, Jenkins R, Whitwell JL, Rossor MN, Fox NC (2003) A longitudinal study of brain volume changes in normal aging using serial registered magnetic resonance imaging. Arch Neurol 60, 989-994
-
(2003)
Arch Neurol
, vol.60
, pp. 989-994
-
-
Scahill, R.I.1
Frost, C.2
Jenkins, R.3
Whitwell, J.L.4
Rossor, M.N.5
Fox, N.C.6
-
19
-
-
0031397650
-
Brain atrophy progression measured from registered serial MRI: Validation and application to Alzheimer's disease
-
Fox NC, Freeborough PA (1997) Brain atrophy progression measured from registered serial MRI: Validation and application to Alzheimer's disease. J Magn Reson Imaging 7, 1069-1075
-
(1997)
J Magn Reson Imaging
, vol.7
, pp. 1069-1075
-
-
Fox, N.C.1
Freeborough, P.A.2
-
20
-
-
0345517129
-
Serial magnetic resonance imaging of cerebral atrophy in preclinical Alzheimer's disease
-
Fox NC, Warrington EK, Rossor MN (1999) Serial magnetic resonance imaging of cerebral atrophy in preclinical Alzheimer's disease. Lancet 353, 2125
-
(1999)
Lancet
, vol.353
, pp. 2125
-
-
Fox, N.C.1
Warrington, E.K.2
Rossor, M.N.3
-
21
-
-
22044433461
-
Measuring atrophy in Alzheimer disease: A serial MRI study over 6 and 12 months
-
Schott JM, Price SL, Frost C, Whitwell JL, Rossor MN, Fox NC (2005) Measuring atrophy in Alzheimer disease: A serial MRI study over 6 and 12 months. Neurology 65, 119-124
-
(2005)
Neurology
, vol.65
, pp. 119-124
-
-
Schott, J.M.1
Price, S.L.2
Frost, C.3
Whitwell, J.L.4
Rossor, M.N.5
Fox, N.C.6
-
22
-
-
0035932961
-
Progressive brain atrophy on serial MRI in dementia with Lewy bodies, AD, and vascular dementia
-
O'Brien JT, Paling S, Barber R (2001) Progressive brain atrophy on serial MRI in dementia with Lewy bodies, AD, and vascular dementia. Neurology 56, 1386-1388
-
(2001)
Neurology
, vol.56
, pp. 1386-1388
-
-
O'Brien, J.T.1
Paling, S.2
Barber, R.3
-
23
-
-
0033549033
-
Correlation between rates of brain atrophy and cognitive decline in AD
-
Fox NC, Scahill RI,CrumWR,RossorMN(1999) Correlation between rates of brain atrophy and cognitive decline in AD. Neurology 52, 1687-1689
-
(1999)
Neurology
, vol.52
, pp. 1687-1689
-
-
Fox, N.C.1
Scahill, R.I.2
Crum, W.R.3
Rossor, M.N.4
-
24
-
-
42549126098
-
Volumetric MRI and cognitive measures in Alzheimer disease: Comparison of markers of progression
-
Ridha BH, Anderson VM, Barnes J, Boyes RG, Price SL, Rossor MN, Whitwell JL, Jenkins L, Black RS, Grundman M, Fox NC (2008) Volumetric MRI and cognitive measures in Alzheimer disease: Comparison of markers of progression. J Neurol 255, 567-574
-
(2008)
J Neurol
, vol.255
, pp. 567-574
-
-
Ridha, B.H.1
Anderson, V.M.2
Barnes, J.3
Boyes, R.G.4
Price, S.L.5
Rossor, M.N.6
Whitwell, J.L.7
Jenkins, L.8
Black, R.S.9
Grundman, M.10
Fox, N.C.11
-
25
-
-
43849112635
-
Neuropsychological correlates of whole brain atrophy in Alzheimer's disease
-
Schott JM, Crutch SJ, Frost C, Warrington EK, Rossor MN, Fox NC (2008) Neuropsychological correlates of whole brain atrophy in Alzheimer's disease. Neuropsychologia 46, 1732-1737
-
(2008)
Neuropsychologia
, vol.46
, pp. 1732-1737
-
-
Schott, J.M.1
Crutch, S.J.2
Frost, C.3
Warrington, E.K.4
Rossor, M.N.5
Fox, N.C.6
-
26
-
-
66549106850
-
Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: Implications for sequence of pathological events in Alzheimer's disease
-
Jack CR, Lowe VJ, Weigand SD, Wiste HJ, Senjem ML, Knopman DS, Shiung MM, Gunter JL, Boeve BF, Kemp BJ, Weiner M, Petersen RC (2009) Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: Implications for sequence of pathological events in Alzheimer's disease. Brain 132 1355-1365
-
(2009)
Brain
, vol.132
, pp. 1355-1365
-
-
Jack, C.R.1
Lowe, V.J.2
Weigand, S.D.3
Wiste, H.J.4
Senjem, M.L.5
Knopman, D.S.6
Shiung, M.M.7
Gunter, J.L.8
Boeve, B.F.9
Kemp, B.J.10
Weiner, M.11
Petersen, R.C.12
-
27
-
-
0034099077
-
Using serial registered brain magnetic resonance imaging to measure disease progression in Alzheimer disease: Power calculations and estimates of sample size to detect treatment effects
-
Fox NC, Cousens S, Scahill R, Harvey RJ, RossorMN(2000) Using serial registered brain magnetic resonance imaging to measure disease progression in Alzheimer disease: Power calculations and estimates of sample size to detect treatment effects. Arch Neurol 57, 339-344
-
(2000)
Arch Neurol
, vol.57
, pp. 339-344
-
-
Fox, N.C.1
Cousens, S.2
Scahill, R.3
Harvey, R.J.4
Rossor, M.N.5
-
28
-
-
20944448555
-
Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial
-
Gilman S, Koller M, Black RS, Jenkins L, Griffith SG, Fox NC, Eisner L, Kirby L, Rovira MB, Forette F, Orgogozo J-M (2005) Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial. Neurology 64, 1553-1562
-
(2005)
Neurology
, vol.64
, pp. 1553-1562
-
-
Gilman, S.1
Koller, M.2
Black, R.S.3
Jenkins, L.4
Griffith, S.G.5
Fox, N.C.6
Eisner, L.7
Kirby, L.8
Rovira, M.B.9
Forette, F.10
Orgogozo, J.-M.11
-
29
-
-
18144415471
-
Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease
-
Fox NC, Black RS, Gilman S, Rossor MN, Griffith SG, Jenkins L, Koller M (2005) Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease. Neurology 64, 1563-1572
-
(2005)
Neurology
, vol.64
, pp. 1563-1572
-
-
Fox, N.C.1
Black, R.S.2
Gilman, S.3
Rossor, M.N.4
Griffith, S.G.5
Jenkins, L.6
Koller, M.7
-
30
-
-
64549152492
-
Long-Term follow-up of patients immunized with AN1792: Reduced functional decline in antibody responders
-
Vellas B, Black R, Thal LJ, Fox NC, Daniels M, McLennan G, Tompkins C, Leibman C, Pomfret M, Grundman M (2009) Long-Term follow-up of patients immunized with AN1792: Reduced functional decline in antibody responders. Curr Alzheimer Res 6, 144-151
-
(2009)
Curr Alzheimer Res
, vol.6
, pp. 144-151
-
-
Vellas, B.1
Black, R.2
Thal, L.J.3
Fox, N.C.4
Daniels, M.5
McLennan, G.6
Tompkins, C.7
Leibman, C.8
Pomfret, M.9
Grundman, M.10
-
31
-
-
47149112621
-
Long-Term effects of A 42 immunisation in Alzheimer's disease: Follow-up of a randomised, placebocontrolled phase I trial
-
Holmes C, Boche D,Wilkinson D, Yadegarfar G, Hopkins V, Bayer A, Jones RW, Bullock R, Love S, Neal JW, Zotova E, Nicoll JAR (2008) Long-Term effects of A 42 immunisation in Alzheimer's disease: Follow-up of a randomised, placebocontrolled phase I trial. Lancet 372, 216-223
-
(2008)
Lancet
, vol.372
, pp. 216-223
-
-
Holmes, C.1
Boche, D.2
Wilkinson, D.3
Yadegarfar, G.4
Hopkins, V.5
Bayer, A.6
Jones, R.W.7
Bullock, R.8
Love, S.9
Neal, J.W.10
Zotova, E.11
Nicoll, J.A.R.12
-
32
-
-
77952314159
-
Robust atrophy rate measurement in Alzheimer's disease using multi-Site serial MRI: Tissue-Specific intensity normalization and parameter selection
-
Leung KK, Clarkson MJ, Bartlett JW, Clegg S, Jack CR, Weiner MW, Fox NC, Ourselin S (2010) Robust atrophy rate measurement in Alzheimer's disease using multi-Site serial MRI: Tissue-Specific intensity normalization and parameter selection. NeuroImage 50, 516-523
-
(2010)
NeuroImage
, vol.50
, pp. 516-523
-
-
Leung, K.K.1
Clarkson, M.J.2
Bartlett, J.W.3
Clegg, S.4
Jack, C.R.5
Weiner, M.W.6
Fox, N.C.7
Ourselin, S.8
-
33
-
-
77952879255
-
Automated cross-Sectional and longitudinal hippocampal volume measurement in mild cognitive impairment and Alzheimer's disease
-
Leung KK, Barnes J, Ridgway GR, Bartlett JW, Clarkson MJ, Macdonald K, Schuff N, Fox NC, Ourselin S (2010) Automated cross-Sectional and longitudinal hippocampal volume measurement in mild cognitive impairment and Alzheimer's disease. NeuroImage 51, 1345-1359
-
(2010)
NeuroImage
, vol.51
, pp. 1345-1359
-
-
Leung, K.K.1
Barnes, J.2
Ridgway, G.R.3
Bartlett, J.W.4
Clarkson, M.J.5
Macdonald, K.6
Schuff, N.7
Fox, N.C.8
Ourselin, S.9
-
34
-
-
50449095930
-
Optimizing the design of clinical trials where the outcome is a rate. Can estimating a baseline rate in a run-in period increase efficiency?
-
Frost C, Kenward MG, Fox NC (2008) Optimizing the design of clinical trials where the outcome is a rate. Can estimating a baseline rate in a run-in period increase efficiency? Stat Med 27, 3717-3731
-
(2008)
Stat Med
, vol.27
, pp. 3717-3731
-
-
Frost, C.1
Kenward, M.G.2
Fox, N.C.3
-
35
-
-
33749442924
-
Combining short interval MRI in Alzheimer's disease: Implications for therapeutic trials
-
Schott JM, Frost C, Whitwell JL, Macmanus DG, Boyes RG, Rossor MN, Fox NC (2006) Combining short interval MRI in Alzheimer's disease: Implications for therapeutic trials. J Neurol 253, 1147-1153
-
(2006)
J Neurol
, vol.253
, pp. 1147-1153
-
-
Schott, J.M.1
Frost, C.2
Whitwell, J.L.3
Macmanus, D.G.4
Boyes, R.G.5
Rossor, M.N.6
Fox, N.C.7
-
36
-
-
0037308009
-
Assessing the onset of structural change in familial Alzheimer's disease
-
Schott J, Fox N, Frost C, Chan D, Jenkin R, Rossor M (2003) Assessing the onset of structural change in familial Alzheimer's disease. Ann Neurol 53, 181-188
-
(2003)
Ann Neurol
, vol.53
, pp. 181-188
-
-
Schott, J.1
Fox, N.2
Frost, C.3
Chan, D.4
Jenkin, R.5
Rossor, M.6
-
37
-
-
33750594921
-
Tracking atrophy progression in familial Alzheimer's disease: A serial MRI study
-
Ridha BH, Barnes J, Bartlett JW, Godbolt A, Pepple T, Rossor MN, Fox NC (2006) Tracking atrophy progression in familial Alzheimer's disease: A serial MRI study. Lancet Neurol 5, 828-834
-
(2006)
Lancet Neurol
, vol.5
, pp. 828-834
-
-
Ridha, B.H.1
Barnes, J.2
Bartlett, J.W.3
Godbolt, A.4
Pepple, T.5
Rossor, M.N.6
Fox, N.C.7
-
38
-
-
0141751616
-
Change in rates of cerebral atrophy over time in early-onset Alzheimer's disease: Longitudinal MRI study
-
Chan D, Janssen JJC, Whitwell JJL, Watt HCH, Jenkins R, Frost C, Rossor MN, Fox NC (2003) Change in rates of cerebral atrophy over time in early-onset Alzheimer's disease: Longitudinal MRI study. Lancet 362, 1121-1122
-
(2003)
Lancet
, vol.362
, pp. 1121-1122
-
-
Chan, D.1
Janssen, J.J.C.2
Whitwell, J.J.L.3
Watt, H.C.H.4
Jenkins, R.5
Frost, C.6
Rossor, M.N.7
Fox, N.C.8
-
39
-
-
0031694255
-
Modeling brain deformations in Alzheimer disease by fluid registration of serial 3D MR images
-
Freeborough PA, Fox NC (1998) Modeling brain deformations in Alzheimer disease by fluid registration of serial 3D MR images. J Comp Asst Tomogr 22, 838-843
-
(1998)
J Comp Asst Tomogr
, vol.22
, pp. 838-843
-
-
Freeborough, P.A.1
Fox, N.C.2
-
40
-
-
0033306649
-
In vivo evidence for post-Adolescent brain maturation in frontal and striatal regions
-
Sowell ER, Thompson PM, Holmes CJ, Jernigan TL, Toga AW (1999) In vivo evidence for post-Adolescent brain maturation in frontal and striatal regions. Nat Neurosci 2, 859-861
-
(1999)
Nat Neurosci
, vol.2
, pp. 859-861
-
-
Sowell, E.R.1
Thompson, P.M.2
Holmes, C.J.3
Jernigan, T.L.4
Toga, A.W.5
-
41
-
-
0035928402
-
Imaging of onset and progression of Alzheimer's disease with voxel-compression mapping of serial magnetic resonance images
-
Fox NC, Crum WR, Scahill RI, Stevens JM, Janssen JC, Rossor MN (2001) Imaging of onset and progression of Alzheimer's disease with voxel-compression mapping of serial magnetic resonance images. Lancet 358, 201-205
-
(2001)
Lancet
, vol.358
, pp. 201-205
-
-
Fox, N.C.1
Crum, W.R.2
Scahill, R.I.3
Stevens, J.M.4
Janssen, J.C.5
Rossor, M.N.6
-
42
-
-
0037007045
-
Mapping the evolution of regional atrophy in Alzheimer's disease: Unbiased analysis of fluid-registered serial MRI
-
Scahill RI, Schott JM, Stevens JM, Rossor MN, Fox NC (2002) Mapping the evolution of regional atrophy in Alzheimer's disease: Unbiased analysis of fluid-registered serial MRI. Proc Natl Acad Sci U S A 99, 4703-4707
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 4703-4707
-
-
Scahill, R.I.1
Schott, J.M.2
Stevens, J.M.3
Rossor, M.N.4
Fox, N.C.5
-
44
-
-
0030874251
-
Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease
-
Minoshima S, Giordani B, Berent S, Frey KA, Foster NL, Kuhl DE (1997) Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease. Ann Neurol 42, 85-94
-
(1997)
Ann Neurol
, vol.42
, pp. 85-94
-
-
Minoshima, S.1
Giordani, B.2
Berent, S.3
Frey, K.A.4
Foster, N.L.5
Kuhl, D.E.6
-
45
-
-
12944259210
-
Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease
-
Small GW, Ercoli LM, Silverman DH, Huang SC, Komo S, Bookheimer SY, Lavretsky H, Miller K, Siddarth P, Rasgon NL, Mazziotta JC, Saxena S,Wu HM, Mega MS, Cummings JL, Saunders AM, Pericak-Vance MA, Roses AD, Barrio JR, Phelps ME (2000) Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease. Proc Natl Acad Sci U S A 97, 6037-6042
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 6037-6042
-
-
Small, G.W.1
Ercoli, L.M.2
Silverman, D.H.3
Huang, S.C.4
Komo, S.5
Bookheimer, S.Y.6
Lavretsky, H.7
Miller, K.8
Siddarth, P.9
Rasgon, N.L.10
Mazziotta, J.C.11
Saxena, S.12
Wu, H.M.13
Mega, M.S.14
Cummings, J.L.15
Saunders, A.M.16
Pericak-Vance, M.A.17
Roses, A.D.18
Barrio, J.R.19
Phelps, M.E.20
more..
-
46
-
-
0028952008
-
The "preclinical phase" of probable Alzheimer's disease
-
Linn RT, Wolf PA, Bachman DL, Knoefel JE, Cobb JL, Belanger AJ, Kaplan EF, D'Agostino RB (1995) The "preclinical phase" of probable Alzheimer's disease. A 13-Year prospective study of the Framingham cohort. Arch Neurol 52, 485-490
-
(1995)
A 13-Year prospective study of the Framingham cohort. Arch Neurol
, vol.52
, pp. 485-490
-
-
Linn, R.T.1
Wolf, P.A.2
Bachman, D.L.3
Knoefel, J.E.4
Cobb, J.L.5
Belanger, A.J.6
Kaplan, E.F.7
D'Agostino, R.B.8
-
47
-
-
0031707071
-
Presymptomatic cognitive deficits in individuals at risk of familial Alzheimer's disease A longitudinal prospective study
-
Fox NC,Warrington EK, Seiffer AL, Agnew SK, Rossor MN (1998) Presymptomatic cognitive deficits in individuals at risk of familial Alzheimer's disease A longitudinal prospective study. Brain 121(Pt 9), 1631-1639
-
(1998)
Brain
, vol.121
, Issue.PART 9
, pp. 1631-1639
-
-
Fox, N.C.1
Warrington, E.K.2
Seiffer, A.L.3
Agnew, S.K.4
Rossor, M.N.5
-
48
-
-
0034776532
-
Patterns of cognitive decline in presymptomatic Alzheimer disease:Aprospective community study
-
Chen P, RatcliffG, Belle SH, Cauley Ja, DeKosky ST, Ganguli M (2001) Patterns of cognitive decline in presymptomatic Alzheimer disease:Aprospective community study. Arch Gen Psychiatry 58, 853-858
-
(2001)
Arch Gen Psychiatry
, vol.58
, pp. 853-858
-
-
Chen, P.1
RatcliffG Belle, S.H.2
Cauley, J.A.3
DeKosky, S.T.4
Ganguli, M.5
-
49
-
-
0035168927
-
Pathologic correlates of nondemented aging, mild cognitive impairment, and early-Stage Alzheimer's disease
-
Morris JC, Price JL (2001) Pathologic correlates of nondemented aging, mild cognitive impairment, and early-Stage Alzheimer's disease. J Mol Neurosci 17, 101-118
-
(2001)
J Mol Neurosci
, vol.17
, pp. 101-118
-
-
Morris, J.C.1
Price, J.L.2
-
50
-
-
0026743110
-
Distribution of Alzheimer-Type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease
-
Arriagada PV, Marzloff K, Hyman BT (1992) Distribution of Alzheimer-Type pathologic changes in nondemented elderly individuals matches the pattern in Alzheimer's disease. Neurology 42, 1681-1688
-
(1992)
Neurology
, vol.42
, pp. 1681-1688
-
-
Arriagada, P.V.1
Marzloff, K.2
Hyman, B.T.3
-
51
-
-
10744232413
-
Imaging brain amyloid in Alzheimer's disease with Pittsburgh compound-B
-
Klunk WE, Engler H, Nordberg A, Wang Y, Blomqvist G, Holt DP, Bergstro M, Savitcheva I, Debnath ML, Barletta J, Price JC, Sandell J, Lopresti BJ, Wall A, Koivisto P, Antoni G, Mathis CA, Langstro B (2004) Imaging brain amyloid in Alzheimer's disease with Pittsburgh compound-B. Ann Neurol 55, 306-319
-
(2004)
Ann Neurol
, vol.55
, pp. 306-319
-
-
Klunk, W.E.1
Engler, H.2
Nordberg, A.3
Wang, Y.4
Blomqvist, G.5
Holt, D.P.6
Bergstro, M.7
Savitcheva, I.8
Debnath, M.L.9
Barletta, J.10
Price, J.C.11
Sandell, J.12
Lopresti, B.J.13
Wall, A.14
Koivisto, P.15
Antoni, G.16
Mathis, C.A.17
Langstro, B.18
-
52
-
-
0037514257
-
Decreased -Amyloid1-42 and increased tau levels in cerebrospinal tau levels in cerebrospinal fluid of patients with Alzheimer disease
-
Sunderland T, Linker G, Mirza N, Putnam KT, Friedman DL, Kimmel LH, Bergeson J, Manetti GJ, Zimmermann M, Tang B, Bartko JJ, Cohen RM (2003) Decreased -Amyloid1-42 and increased tau levels in cerebrospinal tau levels in cerebrospinal fluid of patients with Alzheimer disease. JAMA 289 2094-2103
-
(2003)
JAMA
, vol.289
, pp. 2094-2103
-
-
Sunderland, T.1
Linker, G.2
Mirza, N.3
Putnam, K.T.4
Friedman, D.L.5
Kimmel, L.H.6
Bergeson, J.7
Manetti, G.J.8
Zimmermann, M.9
Tang, B.10
Bartko, J.J.11
Cohen, R.M.12
-
53
-
-
33747048954
-
11C] PIB in a nondemented population: Potential antecedent marker of Alzheimer disease
-
Mintun MA, Larossa GN, Sheline YI, Dence CS, Lee SY, Mach RH, Klunk WE, Mathis Ca, DeKosky ST, Morris JC (2006) [11C]PIB in a nondemented population: Potential antecedent marker of Alzheimer disease. Neurology 67, 446-452
-
(2006)
Neurology
, vol.67
, pp. 446-452
-
-
Mintun, M.A.1
Larossa, G.N.2
Sheline, Y.I.3
Dence, C.S.4
Lee, S.Y.5
Mach, R.H.6
Klunk, W.E.7
Mathis, C.A.8
DeKosky, S.T.9
Morris, J.C.10
-
54
-
-
33947223454
-
Cerebrospinal fluid tau/beta-Amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults
-
Fagan AM, Roe CM, Xiong C, Mintun Ma, Morris JC, Holtzman DM (2007) Cerebrospinal fluid tau/beta-Amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults. Arch Neurol 64, 343-349
-
(2007)
Arch Neurol
, vol.64
, pp. 343-349
-
-
Fagan, A.M.1
Roe, C.M.2
Xiong, C.3
Mintun, M.A.4
Morris, J.C.5
Holtzman, D.M.6
-
55
-
-
77954033257
-
Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging
-
Rowe CC, Ellis KA, Rimajova M, Bourgeat P, Pike KE, Jones G, Fripp J, Tochon-Danguy H, Morandeau L, Keefe GO, Price R, Raniga P, Robins P, Acosta O, Lenzo N, Szoeke C, Salvado O, Head R, Martins R, Masters CL, Ames D, Villemagne VL (2010) Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging. Neurobiol Aging 31, 1275-1283
-
(2010)
Neurobiol Aging
, vol.31
, pp. 1275-1283
-
-
Rowe, C.C.1
Ellis, K.A.2
Rimajova, M.3
Bourgeat, P.4
Pike, K.E.5
Jones, G.6
Fripp, J.7
Tochon-Danguy, H.8
Morandeau, L.9
Keefe, G.O.10
Price, R.11
Raniga, P.12
Robins, P.13
Acosta, O.14
Lenzo, N.15
Szoeke, C.16
Salvado, O.17
Head, R.18
Martins, R.19
Masters, C.L.20
Ames, D.21
Villemagne, V.L.22
more..
-
56
-
-
72049130805
-
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
-
Jack CR, Knopman DS, Jagust WJ, Shaw LM, Aisen PS, Weiner MW, Petersen RC, Trojanowski JQ (2010) Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol 9, 119-128
-
(2010)
Lancet Neurol
, vol.9
, pp. 119-128
-
-
Jack, C.R.1
Knopman, D.S.2
Jagust, W.J.3
Shaw, L.M.4
Aisen, P.S.5
Weiner, M.W.6
Petersen, R.C.7
Trojanowski, J.Q.8
-
57
-
-
79956098248
-
Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
Sperling RA, Aisen PS, Beckett LA, Bennett Da, Craft S, Fagan AM, Iwatsubo T, Jack CR, Kaye J, Montine TJ, Park DC, Reiman EM, Rowe CC, Siemers E, Stern Y, Yaffe K, Carrillo MC, Thies B, Morrison-Bogorad M, Wagster MV, Phelps CH (2011) Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7, 280-292
-
(2011)
Alzheimers Dement
, vol.7
, pp. 280-292
-
-
Sperling, R.A.1
Aisen, P.S.2
Beckett, L.A.3
Bennett Da Craft, S.4
Fagan, A.M.5
Iwatsubo, T.6
Jack, C.R.7
Kaye, J.8
Montine, T.J.9
Park, D.C.10
Reiman, E.M.11
Rowe, C.C.12
Siemers, E.13
Stern, Y.14
Yaffe, K.15
Carrillo, M.C.16
Thies, B.17
Morrison-Bogorad, M.18
Wagster, M.V.19
Phelps, C.H.20
more..
-
58
-
-
0035826782
-
Practice parameter: Diagnosis of dementia (an evidencebased review report of the quality standards subcommittee of the american academy of neurology
-
Knopman DS, DeKosky ST, Cummings JL, Chui H, Corey-Bloom J, Relkin N, Small GW, Miller B, Stevens JC (2001) Practice parameter: Diagnosis of dementia (an evidencebased review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 56, 1143-1153
-
(2001)
Neurology
, vol.56
, pp. 1143-1153
-
-
Knopman, D.S.1
DeKosky, S.T.2
Cummings, J.L.3
Chui, H.4
Corey-Bloom, J.5
Relkin, N.6
Small, G.W.7
Miller, B.8
Stevens, J.C.9
-
59
-
-
77956629252
-
EFNS guidelines for the diagnosis and management of Alzheimer's disease
-
Hort J, O'Brien JT, Gainotti G, Pirttila T, Popescu BO, Rektorova I, Sorbi S, Scheltens P (2010) EFNS guidelines for the diagnosis and management of Alzheimer's disease. Eur J Neurol 17, 1236-1248
-
(2010)
Eur J Neurol
, vol.17
, pp. 1236-1248
-
-
Hort, J.1
O'Brien, J.T.2
Gainotti, G.3
Pirttila, T.4
Popescu, B.O.5
Rektorova, I.6
Sorbi, S.7
Scheltens, P.8
-
61
-
-
58149395966
-
Medial temporal lobe atrophy on MRI scans and the diagnosis of Alzheimer disease
-
Duara R, Loewenstein DA, Potter E, Appel J, Greig MT, Urs R, Shen Q, Raj A, Small B, BarkerW, Schofield E,Wu Y, Potter H (2008) Medial temporal lobe atrophy on MRI scans and the diagnosis of Alzheimer disease. Neurology 71, 1986-1992
-
(2008)
Neurology
, vol.71
, pp. 1986-1992
-
-
Duara, R.1
Loewenstein, D.A.2
Potter, E.3
Appel, J.4
Greig, M.T.5
Urs, R.6
Shen, Q.7
Raj, A.8
Small, B.9
Barker, W.10
Schofield, E.11
Wu, Y.12
Potter, H.13
-
62
-
-
0027194145
-
The radiologic prediction of Alzheimer disease: The atrophic hippocampal formation
-
de Leon M, Golomb J, George A, Convit A, Tarshish C, McRae T, De Santi S, Smith G, Ferris S, Noz M (1993) The radiologic prediction of Alzheimer disease: The atrophic hippocampal formation. AJNRAmJ Neuroradiol 14, 897-906
-
(1993)
AJNRAmJ Neuroradiol
, vol.14
, pp. 897-906
-
-
De Leon, M.1
Golomb, J.2
George, A.3
Convit, A.4
Tarshish, C.5
McRae, T.6
De Santi, S.7
Smith, G.8
Ferris, S.9
Noz, M.10
-
63
-
-
0344889207
-
Prediction ofADwith MRI-based hippocampal volume in mild cognitive impairment
-
Jack C, Peterson R, Yue CX, O'Brien P, Smith GE, Ivnik R, Boeve B,Waring S, Tanglaos E, Kokmen E (1999) Prediction ofADwith MRI-based hippocampal volume in mild cognitive impairment. Neurology 52, 1397-1403
-
(1999)
Neurology
, vol.52
, pp. 1397-1403
-
-
Jack, C.1
Peterson, R.2
Yue, C.X.3
O'Brien, P.4
Smith, G.E.5
Ivnik, R.6
Boeve, B.7
Waring, S.8
Tanglaos, E.9
Kokmen, E.10
-
64
-
-
3142539896
-
Medial temporal lobe atrophy on MRI predicts dementia in patients with mild cognitive impairment
-
Korf ESC, Wahlund L-O, Visser PJ, Scheltens P (2004) Medial temporal lobe atrophy on MRI predicts dementia in patients with mild cognitive impairment. Neurology 63, 94-100
-
(2004)
Neurology
, vol.63
, pp. 94-100
-
-
Korf, E.S.C.1
Wahlund, L.-O.2
Visser, P.J.3
Scheltens, P.4
-
65
-
-
33846048774
-
Qualitative estimates of medial temporal atrophy as a predictor of progression from mild cognitive impairment to dementia
-
DeCarli C, Frisoni GB, Clark CM, Harvey D, Grundman M, Petersen RC, Thal LJ, Jin S, Jack CR, Scheltens P (2007) Qualitative estimates of medial temporal atrophy as a predictor of progression from mild cognitive impairment to dementia. Arch Neurol 64, 108-115
-
(2007)
Arch Neurol
, vol.64
, pp. 108-115
-
-
DeCarli, C.1
Frisoni, G.B.2
Clark, C.M.3
Harvey, D.4
Grundman, M.5
Petersen, R.C.6
Thal, L.J.7
Jin, S.8
Jack, C.R.9
Scheltens, P.10
-
66
-
-
34447322271
-
Research criteria for the diagnosis of Alzheimer's disease: Revising the NINCDS-ADRDA criteria
-
Dubois B, Feldman HH, Jacova C, Dekosky ST, Barberger-Gateau P, Cummings J, Delacourte A, Galasko D, Gauthier S, Jicha G,Meguro K, O'brien J, Pasquier F, Robert P, Rossor M, Salloway S, Stern Y, Visser PJ, Scheltens P (2007) Research criteria for the diagnosis of Alzheimer's disease: Revising the NINCDS-ADRDA criteria. Lancet Neurol 6, 734-746
-
(2007)
Lancet Neurol
, vol.6
, pp. 734-746
-
-
Dubois, B.1
Feldman, H.H.2
Jacova, C.3
Dekosky, S.T.4
Barberger-Gateau, P.5
Cummings, J.6
Delacourte, A.7
Galasko, D.8
Gauthier, S.9
Jicha, G.10
Meguro, K.11
O'brien, J.12
Pasquier, F.13
Robert, P.14
Rossor, M.15
Salloway, S.16
Stern, Y.17
Visser, P.J.18
Scheltens, P.19
-
67
-
-
0035069988
-
Patterns of temporal lobe atrophy in semantic dementia and Alzheimer's disease
-
Chan D, Fox NC, Scahill RI, Crum WR, Whitwell JL, Leschziner G, Rossor AM, Stevens JM, Cipolotti L, Rossor MN (2001) Patterns of temporal lobe atrophy in semantic dementia and Alzheimer's disease. Ann Neurol 49, 433-442
-
(2001)
Ann Neurol
, vol.49
, pp. 433-442
-
-
Chan, D.1
Fox, N.C.2
Scahill, R.I.3
Crum, W.R.4
Whitwell, J.L.5
Leschziner, G.6
Rossor, A.M.7
Stevens, J.M.8
Cipolotti, L.9
Rossor, M.N.10
-
68
-
-
34247331828
-
CSFbiomarkers and medial temporal lobe atrophy predict dementia in mild cognitive impairment
-
Bouwman FH, Schoonenboom SNM, van der Flier WM, van Elk EJ, Kok A, Barkhof F, Blankenstein MA, Scheltens P (2007)CSFbiomarkers and medial temporal lobe atrophy predict dementia in mild cognitive impairment. Neurobiol Aging 28, 1070-1074
-
(2007)
Neurobiol Aging
, vol.28
, pp. 1070-1074
-
-
Bouwman, F.H.1
Schoonenboom, S.N.M.2
Van Der Flier, W.M.3
Van Elk, E.J.4
Kok, A.5
Barkhof, F.6
Blankenstein, M.A.7
Scheltens, P.8
-
69
-
-
70349582720
-
Conversion of amyloid positive and negative MCI to AD over 3 years: An 11C-PIB PET study
-
Okello A, Koivunen J, Edison P, Archer HA, Turkheimer FE, Nagren K, Bullock R,Walker Z, Kennedy A, Fox NC, Rossor MN, Rinne JO, Brooks DJ (2009) Conversion of amyloid positive and negative MCI to AD over 3 years: An 11C-PIB PET study. Neurology 73, 754-760
-
(2009)
Neurology
, vol.73
, pp. 754-760
-
-
Okello, A.1
Koivunen, J.2
Edison, P.3
Archer, H.A.4
Turkheimer, F.E.5
Nagren, K.6
Bullock, R.7
Walker, Z.8
Kennedy, A.9
Fox, N.C.10
Rossor, M.N.11
Rinne, J.O.12
Brooks, D.J.13
-
70
-
-
76849095847
-
The clinical use of structural MRI in Alzheimer disease
-
Frisoni GB, Fox NC, Jack CR, Scheltens P, Thompson PM (2010) The clinical use of structural MRI in Alzheimer disease. Nature Rev Neurol 6, 67-77
-
(2010)
Nature Rev Neurol
, vol.6
, pp. 67-77
-
-
Frisoni, G.B.1
Fox, N.C.2
Jack, C.R.3
Scheltens, P.4
Thompson, P.M.5
-
71
-
-
77953518555
-
Alzheimer's disease: Clinical trials and drug development
-
Mangialasche F, Solomon A,Winblad B, Mecocci P, Kivipelto M(2010) Alzheimer's disease: Clinical trials and drug development. Lancet Neurol 9, 702-716
-
(2010)
Lancet Neurol
, vol.9
, pp. 702-716
-
-
Mangialasche, F.1
Solomon, A.2
Winblad, B.3
Mecocci, P.4
Kivipelto, M.5
-
72
-
-
78651266932
-
Autosomal-Dominant Alzheimer's disease: Areviewand proposal for the prevention of Alzheimer's disease
-
Bateman RJ, Aisen PS, Strooper BD, Fox NC, Lemere CA, Ringman JM (2011) Autosomal-Dominant Alzheimer's disease: Areviewand proposal for the prevention of Alzheimer's disease. Alzheimers Res Ther 3, 1-13
-
(2011)
Alzheimers Res Ther
, vol.3
, pp. 1-13
-
-
Bateman, R.J.1
Aisen, P.S.2
Strooper, B.D.3
Fox, N.C.4
Lemere, C.A.5
Ringman, J.M.6
-
73
-
-
77955453909
-
Diagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly people
-
De Meyer G, Shapiro F, Vanderstichele H, Vanmechelen E, Engelborghs S, De Deyn PP, Coart E, Hansson O, Minthon L, Zetterberg H, Blennow K, Shaw L, Trojanowski JQ (2010) Diagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly people. Archives Neurol 67, 949-956
-
(2010)
Archives Neurol
, vol.67
, pp. 949-956
-
-
De Meyer, G.1
Shapiro, F.2
Vanderstichele, H.3
Vanmechelen, E.4
Engelborghs, S.5
De Deyn, P.P.6
Coart, E.7
Hansson, O.8
Minthon, L.9
Zetterberg, H.10
Blennow, K.11
Shaw, L.12
Trojanowski, J.Q.13
-
74
-
-
78650906323
-
Increased brain atrophy rates in cognitively normal older adults with low cerebrospinal fluid A-1-42
-
Schott JM, Bartlett JW, Fox NC, Barnes J (2010) Increased brain atrophy rates in cognitively normal older adults with low cerebrospinal fluid A-1-42. Ann Neurol 68, 825-834
-
(2010)
Ann Neurol
, vol.68
, pp. 825-834
-
-
Schott, J.M.1
Bartlett, J.W.2
Fox, N.C.3
Barnes, J.4
-
75
-
-
77950538544
-
Wholebrain atrophy rate and CSF biomarker levels in MCI and AD: A longitudinal study
-
Sluimer JD, Bouwman FH, Vrenken H, Blankenstein M, a, Barkhof F, van der Flier WM, Scheltens P (2010) Wholebrain atrophy rate and CSF biomarker levels in MCI and AD: A longitudinal study. Neurobiol Aging 31, 758-764
-
(2010)
Neurobiol Aging
, vol.31
, pp. 758-764
-
-
Sluimer, J.D.1
Bouwman, F.H.2
Vrenken, H.3
Blankenstein, M.4
Barkhof, A.F.5
Van Der Flier, W.M.6
Scheltens, P.7
|