메뉴 건너뛰기




Volumn 62, Issue 1, 2013, Pages 87-99

B lymphocyte inhibition of anti-tumor response depends on expansion of Treg but is independent of B-cell IL-10 secretion

Author keywords

B lymphocyte; B cell deficient mice (BCDM); IL 10; Immune competent mice (BALB c); T regulatory cells (Treg)

Indexed keywords

INTERLEUKIN 10;

EID: 84872489363     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-012-1313-6     Document Type: Article
Times cited : (67)

References (35)
  • 1
    • 0034013685 scopus 로고    scopus 로고
    • Regulatory role of mature B cells in a murine model of inflammatory bowel disease
    • 10784605 10.1093/intimm/12.5.597 1:CAS:528:DC%2BD3cXjs1CksbY%3D
    • Mizoguchi E, Mizoguchi A, Preffer FI, Bhan AK (2000) Regulatory role of mature B cells in a murine model of inflammatory bowel disease. Int Immunol 12:597
    • (2000) Int Immunol , vol.12 , pp. 597
    • Mizoguchi, E.1    Mizoguchi, A.2    Preffer, F.I.3    Bhan, A.K.4
  • 2
    • 0036197923 scopus 로고    scopus 로고
    • Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation
    • 11869683 10.1016/S1074-7613(02)00274-1 1:CAS:528:DC%2BD38XitVCisrw%3D
    • Mizoguchi A, Mizoguchi E, Takedatsu H, Blumberg RS, Bhan AK (2002) Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation. Immunity 16:219
    • (2002) Immunity , vol.16 , pp. 219
    • Mizoguchi, A.1    Mizoguchi, E.2    Takedatsu, H.3    Blumberg, R.S.4    Bhan, A.K.5
  • 3
    • 0030666959 scopus 로고    scopus 로고
    • Suppressive role of B cells in chronic colitis of T cell receptor alpha mutant mice
    • 9362534 10.1084/jem.186.10.1749 1:CAS:528:DyaK2sXnsVeitrk%3D
    • Mizoguchi A, Mizoguchi E, Smith RN, Preffer FI, Bhan AK (1997) Suppressive role of B cells in chronic colitis of T cell receptor alpha mutant mice. J Exp Med 186:1749
    • (1997) J Exp Med , vol.186 , pp. 1749
    • Mizoguchi, A.1    Mizoguchi, E.2    Smith, R.N.3    Preffer, F.I.4    Bhan, A.K.5
  • 4
    • 0037450740 scopus 로고    scopus 로고
    • Prevention of arthritis by interleukin 10-producing B cells
    • 12591906 10.1084/jem.20021293 1:CAS:528:DC%2BD3sXhtlOlsLw%3D
    • Mauri C, Gray D, Mushtaq N, Londei M (2003) Prevention of arthritis by interleukin 10-producing B cells. J Exp Med 197:489
    • (2003) J Exp Med , vol.197 , pp. 489
    • Mauri, C.1    Gray, D.2    Mushtaq, N.3    Londei, M.4
  • 5
    • 33747880415 scopus 로고    scopus 로고
    • Inhibitory effects of B cells on antitumor immunity
    • 16885377 10.1158/0008-5472.CAN-05-3766 1:CAS:528:DC%2BD28XnsFyqsrs%3D
    • Inoue S, Leitner WW, Golding B, Scott D (2006) Inhibitory effects of B cells on antitumor immunity. Cancer research 66:7741
    • (2006) Cancer Research , vol.66 , pp. 7741
    • Inoue, S.1    Leitner, W.W.2    Golding, B.3    Scott, D.4
  • 7
    • 0031863680 scopus 로고    scopus 로고
    • B cells inhibit induction of T cell-dependent tumor immunity
    • 9585241 10.1038/nm0598-627 1:CAS:528:DyaK1cXjtFKgtrY%3D
    • Qin Z, Richter G, Schuler T, Ibe S, Cao X, Blankenstein T (1998) B cells inhibit induction of T cell-dependent tumor immunity. Nat Med 4:627
    • (1998) Nat Med , vol.4 , pp. 627
    • Qin, Z.1    Richter, G.2    Schuler, T.3    Ibe, S.4    Cao, X.5    Blankenstein, T.6
  • 8
    • 0030657467 scopus 로고    scopus 로고
    • High-titer HER-2/neu protein-specific antibody can be detected in patients with early-stage breast cancer
    • 9363867 1:STN:280:DyaK1c%2FivVCqtQ%3D%3D
    • Disis ML, Pupa SM, Gralow JR, Dittadi R, Menard S, Cheever MA (1997) High-titer HER-2/neu protein-specific antibody can be detected in patients with early-stage breast cancer. J Clin Oncol 15:3363
    • (1997) J Clin Oncol , vol.15 , pp. 3363
    • Disis, M.L.1    Pupa, S.M.2    Gralow, J.R.3    Dittadi, R.4    Menard, S.5    Cheever, M.A.6
  • 10
    • 42649094145 scopus 로고    scopus 로고
    • Surmounting tumor-induced immune suppression by frequent vaccination or immunization in the absence of B cells
    • 18391756 10.1097/CJI.0b013e31816bc74d
    • Oizumi S, Deyev V, Yamazaki K, Schreiber T, Strbo N, Rosenblatt J, Podack ER (2008) Surmounting tumor-induced immune suppression by frequent vaccination or immunization in the absence of B cells. J Immunother 31:394
    • (2008) J Immunother , vol.31 , pp. 394
    • Oizumi, S.1    Deyev, V.2    Yamazaki, K.3    Schreiber, T.4    Strbo, N.5    Rosenblatt, J.6    Podack, E.R.7
  • 11
    • 79955539126 scopus 로고    scopus 로고
    • The absence of B lymphocytes reduces the number and function of T-regulatory cells and enhances the anti-tumor response in a murine tumor model
    • Tadmor T, Zhang Y, Cho HM, Podack ER, Rosenblatt JD (2011) The absence of B lymphocytes reduces the number and function of T-regulatory cells and enhances the anti-tumor response in a murine tumor model. Cancer Immunol Immunother
    • (2011) Cancer Immunol Immunother
    • Tadmor, T.1    Zhang, Y.2    Cho, H.M.3    Podack, E.R.4    Rosenblatt, J.D.5
  • 12
    • 79956131523 scopus 로고    scopus 로고
    • Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4+ T cells to T-regulatory cells
    • 21444674 10.1158/0008-5472.CAN-10-4316 1:CAS:528:DC%2BC3MXmtVGlt7w%3D
    • Olkhanud PB, Damdinsuren B, Bodogai M, Gress RE, Sen R, Wejksza K, Malchinkhuu E, Wersto RP, Biragyn A (2011) Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4+ T cells to T-regulatory cells. Cancer Res 71:3505
    • (2011) Cancer Res , vol.71 , pp. 3505
    • Olkhanud, P.B.1    Damdinsuren, B.2    Bodogai, M.3    Gress, R.E.4    Sen, R.5    Wejksza, K.6    Malchinkhuu, E.7    Wersto, R.P.8    Biragyn, A.9
  • 13
    • 56649091213 scopus 로고    scopus 로고
    • Role of TGF-Beta in the induction of Foxp3 expression and T regulatory cell function
    • 18810612 10.1007/s10875-008-9240-1 1:CAS:528:DC%2BD1cXhtl2qu7vI
    • Shevach EM, Davidson TS, Huter EN, Dipaolo RA, Andersson J (2008) Role of TGF-Beta in the induction of Foxp3 expression and T regulatory cell function. J Clin Immunol 28:640
    • (2008) J Clin Immunol , vol.28 , pp. 640
    • Shevach, E.M.1    Davidson, T.S.2    Huter, E.N.3    Dipaolo, R.A.4    Andersson, J.5
  • 15
    • 12244285937 scopus 로고    scopus 로고
    • Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo
    • 15623559 10.1073/pnas.0408197102 1:CAS:528:DC%2BD2MXptFSrsg%3D%3D
    • Chen ML, Pittet MJ, Gorelik L, Flavell RA, Weissleder R, von Boehmer H, Khazaie K (2005) Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo. Proc Natl Acad Sci USA 102:419
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 419
    • Chen, M.L.1    Pittet, M.J.2    Gorelik, L.3    Flavell, R.A.4    Weissleder, R.5    Von Boehmer, H.6    Khazaie, K.7
  • 16
    • 77149164820 scopus 로고    scopus 로고
    • CD4(+)CD25(+) T regulatory cells inhibit CD8(+) IFN-gamma production during acute and chronic FIV infection utilizing a membrane TGF-beta-dependent mechanism
    • 20156102 10.1089/aid.2009.0162 1:CAS:528:DC%2BC3cXitVSru78%3D
    • Fogle JE, Mexas AM, Tompkins WA, Tompkins MB (2010) CD4(+)CD25(+) T regulatory cells inhibit CD8(+) IFN-gamma production during acute and chronic FIV infection utilizing a membrane TGF-beta-dependent mechanism. AIDS Res Hum Retroviruses 26:201
    • (2010) AIDS Res Hum Retroviruses , vol.26 , pp. 201
    • Fogle, J.E.1    Mexas, A.M.2    Tompkins, W.A.3    Tompkins, M.B.4
  • 17
  • 18
    • 63149121284 scopus 로고    scopus 로고
    • Human circulating CD4+CD25highFoxp3+ regulatory T cells kill autologous CD8+ but not CD4+ responder cells by Fas-mediated apoptosis
    • 19155494 1:CAS:528:DC%2BD1MXnsVersQ%3D%3D
    • Strauss L, Bergmann C, Whiteside TL (2009) Human circulating CD4+CD25highFoxp3+ regulatory T cells kill autologous CD8+ but not CD4+ responder cells by Fas-mediated apoptosis. J Immunol 182:1469
    • (2009) J Immunol , vol.182 , pp. 1469
    • Strauss, L.1    Bergmann, C.2    Whiteside, T.L.3
  • 19
    • 56249126742 scopus 로고    scopus 로고
    • Apoptosis as a mechanism of T-regulatory cell homeostasis and suppression
    • 18794907 10.1038/icb.2008.62 1:CAS:528:DC%2BD1cXhtlKmtLnI
    • Yolcu ES, Ash S, Kaminitz A, Sagiv Y, Askenasy N, Yarkoni S (2008) Apoptosis as a mechanism of T-regulatory cell homeostasis and suppression. Immunol Cell Biol 86:650
    • (2008) Immunol Cell Biol , vol.86 , pp. 650
    • Yolcu, E.S.1    Ash, S.2    Kaminitz, A.3    Sagiv, Y.4    Askenasy, N.5    Yarkoni, S.6
  • 20
    • 58749088782 scopus 로고    scopus 로고
    • Inverse correlation between NKG2D expression on CD8+ T cells and the frequency of CD4+CD25+ regulatory T cells in patients with esophageal cancer
    • 18564160 10.1111/j.1442-2050.2008.00855.x 1:STN:280: DC%2BD1M7itVGmtw%3D%3D
    • Osaki T, Saito H, Fukumoto Y, Yamada Y, Fukuda K, Tatebe S, Tsujitani S, Ikeguchi M (2009) Inverse correlation between NKG2D expression on CD8+ T cells and the frequency of CD4+CD25+ regulatory T cells in patients with esophageal cancer. Dis Esophagus 22:49
    • (2009) Dis Esophagus , vol.22 , pp. 49
    • Osaki, T.1    Saito, H.2    Fukumoto, Y.3    Yamada, Y.4    Fukuda, K.5    Tatebe, S.6    Tsujitani, S.7    Ikeguchi, M.8
  • 21
    • 33750691006 scopus 로고    scopus 로고
    • The role of regulatory T cells in the control of natural killer cells: Relevance during tumor progression
    • 17100888 10.1111/j.1600-065X.2006.00445.x 1:CAS:528:DC%2BD28XhtlClsrzJ
    • Ghiringhelli F, Menard C, Martin F, Zitvogel L (2006) The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression. Immunol Rev 214:229
    • (2006) Immunol Rev , vol.214 , pp. 229
    • Ghiringhelli, F.1    Menard, C.2    Martin, F.3    Zitvogel, L.4
  • 22
    • 31144468294 scopus 로고    scopus 로고
    • CD4+CD25+ T regulatory cells suppress NK cell-mediated immunotherapy of cancer
    • 16424187 1:CAS:528:DC%2BD28XlsFynsw%3D%3D
    • Smyth MJ, Teng MW, Swann J, Kyparissoudis K, Godfrey DI, Hayakawa Y (2006) CD4+CD25+ T regulatory cells suppress NK cell-mediated immunotherapy of cancer. J Immunol 176:1582
    • (2006) J Immunol , vol.176 , pp. 1582
    • Smyth, M.J.1    Teng, M.W.2    Swann, J.3    Kyparissoudis, K.4    Godfrey, D.I.5    Hayakawa, Y.6
  • 23
    • 13544271161 scopus 로고    scopus 로고
    • Cutting edge: Contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism
    • 15699103 1:CAS:528:DC%2BD2MXhtV2ku7w%3D
    • Gondek DC, Lu LF, Quezada SA, Sakaguchi S, Noelle RJ (2005) Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. J Immunol 174:1783
    • (2005) J Immunol , vol.174 , pp. 1783
    • Gondek, D.C.1    Lu, L.F.2    Quezada, S.A.3    Sakaguchi, S.4    Noelle, R.J.5
  • 24
    • 48249103057 scopus 로고    scopus 로고
    • Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation
    • 18635688 10.1073/pnas.0711106105 1:CAS:528:DC%2BD1cXptFOhurw%3D
    • Onishi Y, Fehervari Z, Yamaguchi T, Sakaguchi S (2008) Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation. Proc Natl Acad Sci USA 105:10113
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 10113
    • Onishi, Y.1    Fehervari, Z.2    Yamaguchi, T.3    Sakaguchi, S.4
  • 25
    • 34848922720 scopus 로고    scopus 로고
    • Cutting edge: Primary B lymphocytes preferentially expand allogeneic FoxP3+CD4 T cells
    • 1:CAS:528:DC%2BD2sXosVyrtbc%3D
    • Chen X, Jensen PE (2007) Cutting edge: primary B lymphocytes preferentially expand allogeneic FoxP3+CD4 T cells. J Immunol (Baltimore, Md.: 1950) 179:2046
    • (2007) J Immunol (Baltimore, Md.: 1950) , vol.179 , pp. 2046
    • Chen, X.1    Jensen, P.E.2
  • 26
    • 34447339202 scopus 로고    scopus 로고
    • Naive B cells generate regulatory T cells in the presence of a mature immunologic synapse
    • 17392507 10.1182/blood-2006-10-053793 1:CAS:528:DC%2BD2sXhtVSgsb3J
    • Reichardt P, Dornbach B, Rong S, Beissert S, Gueler F, Loser K, Gunzer M (2007) Naive B cells generate regulatory T cells in the presence of a mature immunologic synapse. Blood 110:1519
    • (2007) Blood , vol.110 , pp. 1519
    • Reichardt, P.1    Dornbach, B.2    Rong, S.3    Beissert, S.4    Gueler, F.5    Loser, K.6    Gunzer, M.7
  • 27
    • 78650392922 scopus 로고    scopus 로고
    • Delivery of NKG2D ligand using an anti-HER2 antibody-NKG2D ligand fusion protein results in an enhanced innate and adaptive antitumor response
    • 21159634 10.1158/0008-5472.CAN-10-1047 1:CAS:528:DC%2BC3cXhsFGrt7vF
    • Cho HM, Rosenblatt JD, Tolba K, Shin SJ, Shin DS, Calfa C, Zhang Y, Shin SU (2010) Delivery of NKG2D ligand using an anti-HER2 antibody-NKG2D ligand fusion protein results in an enhanced innate and adaptive antitumor response. Cancer Res 70:10121
    • (2010) Cancer Res , vol.70 , pp. 10121
    • Cho, H.M.1    Rosenblatt, J.D.2    Tolba, K.3    Shin, S.J.4    Shin, D.S.5    Calfa, C.6    Zhang, Y.7    Shin, S.U.8
  • 28
    • 17044430217 scopus 로고    scopus 로고
    • Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
    • 15795373 10.1073/pnas.0501701102 1:CAS:528:DC%2BD2MXjsFemtLo%3D
    • Wan YY, Flavell RA (2005) Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter. Proc Natl Acad Sci USA 102:5126
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5126
    • Wan, Y.Y.1    Flavell, R.A.2
  • 29
    • 75749087574 scopus 로고    scopus 로고
    • B10 cells and regulatory B cells balance immune responses during inflammation, autoimmunity, and cancer
    • 20146707 10.1111/j.1749-6632.2009.05137.x 1:CAS:528:DC%2BC3cXisVehsrY%3D
    • DiLillo DJ, Matsushita T, Tedder TF (2010) B10 cells and regulatory B cells balance immune responses during inflammation, autoimmunity, and cancer. Ann NY Acad Sci 1183:38
    • (2010) Ann NY Acad Sci , vol.1183 , pp. 38
    • Dilillo, D.J.1    Matsushita, T.2    Tedder, T.F.3
  • 30
    • 0037388954 scopus 로고    scopus 로고
    • Costimulation via OX40L expressed by B cells is sufficient to determine the extent of primary CD4 cell expansion and Th2 cytokine secretion in vivo
    • 12668647 10.1084/jem.20021290 1:CAS:528:DC%2BD3sXivFaisb4%3D
    • Linton PJ, Bautista B, Biederman E, Bradley ES, Harbertson J, Kondrack RM, Padrick RC, Bradley LM (2003) Costimulation via OX40L expressed by B cells is sufficient to determine the extent of primary CD4 cell expansion and Th2 cytokine secretion in vivo. J Exp Med 197:875
    • (2003) J Exp Med , vol.197 , pp. 875
    • Linton, P.J.1    Bautista, B.2    Biederman, E.3    Bradley, E.S.4    Harbertson, J.5    Kondrack, R.M.6    Padrick, R.C.7    Bradley, L.M.8
  • 31
    • 0036687666 scopus 로고    scopus 로고
    • Availability of antigen-presenting cells can determine the extent of CD4 effector expansion and priming for secretion of Th2 cytokines in vivo
    • 12209647 10.1002/1521-4141(200208)32:8<2338: AID-IMMU2338>3.0.CO;2- R 1:CAS:528:DC%2BD38XmslSltbw%3D
    • Bradley LM, Harbertson J, Biederman E, Zhang Y, Bradley SM, Linton PJ (2002) Availability of antigen-presenting cells can determine the extent of CD4 effector expansion and priming for secretion of Th2 cytokines in vivo. Eur J Immunol 32:2338
    • (2002) Eur J Immunol , vol.32 , pp. 2338
    • Bradley, L.M.1    Harbertson, J.2    Biederman, E.3    Zhang, Y.4    Bradley, S.M.5    Linton, P.J.6
  • 32
    • 58849161852 scopus 로고    scopus 로고
    • B lymphocytes promote expansion of regulatory T cells in oral tolerance: Powerful induction by antigen coupled to cholera toxin B subunit
    • 1:CAS:528:DC%2BD1cXhsVCksbfN
    • Sun JB, Flach CF, Czerkinsky C, Holmgren J (2008) B lymphocytes promote expansion of regulatory T cells in oral tolerance: powerful induction by antigen coupled to cholera toxin B subunit. J Immunol (Baltimore, Md.: 1950) 181:8278
    • (2008) J Immunol (Baltimore, Md.: 1950) , vol.181 , pp. 8278
    • Sun, J.B.1    Flach, C.F.2    Czerkinsky, C.3    Holmgren, J.4
  • 33
    • 65449188259 scopus 로고    scopus 로고
    • Selective targeting of B cells with agonistic anti-CD40 is an efficacious strategy for the generation of induced regulatory T2-like B cells and for the suppression of lupus in MRL/lpr mice
    • 19265127 10.4049/jimmunol.0803052 1:CAS:528:DC%2BD1MXis12it7o%3D
    • Blair PA, Chavez-Rueda KA, Evans JG, Shlomchik MJ, Eddaoudi A, Isenberg DA, Ehrenstein MR, Mauri C (2009) Selective targeting of B cells with agonistic anti-CD40 is an efficacious strategy for the generation of induced regulatory T2-like B cells and for the suppression of lupus in MRL/lpr mice. J Immunol 182:3492
    • (2009) J Immunol , vol.182 , pp. 3492
    • Blair, P.A.1    Chavez-Rueda, K.A.2    Evans, J.G.3    Shlomchik, M.J.4    Eddaoudi, A.5    Isenberg, D.A.6    Ehrenstein, M.R.7    Mauri, C.8
  • 35
    • 0037029715 scopus 로고    scopus 로고
    • Increase in immune cell infiltration with progression of oral epithelium from hyperkeratosis to dysplasia and carcinoma
    • 11986779 10.1038/sj.bjc.6600282 1:STN:280:DC%2BD383pslGltg%3D%3D
    • Gannot G, Gannot I, Vered H, Buchner A, Keisari Y (2002) Increase in immune cell infiltration with progression of oral epithelium from hyperkeratosis to dysplasia and carcinoma. Br J Cancer 86:1444
    • (2002) Br J Cancer , vol.86 , pp. 1444
    • Gannot, G.1    Gannot, I.2    Vered, H.3    Buchner, A.4    Keisari, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.