Acetylcholinesterase from human erythrocytes membrane: A screen for evaluating the activity of some traditional plant extracts

Cellular and Molecular Biology

Volumn 58, Issue 1, 2012, Pages 160-169

  Srivastava, N ^a   Sharma, R K ^a   Singh, N ^b   Sharma, B ^a  

^a UNIVERSITY OF ALLAHABAD   (India)

^b CSM University Kanpur   (India)

Author keywords

Acetylcholinesterase inhibition; Alzheimers disease; Aqueous plant extract; Argemone mexicana; Calotropis procera; Cannabis sativa; Datura metal; Thevitia peruviana

Indexed keywords

ACETYLCHOLINESTERASE; ARGEMONE OIL; BIOLOGICAL MARKER; CALOTROPIS PROCERA EXTRACT; CANNABIS; CHOLINESTERASE INHIBITOR; DATURA METAL EXTRACT; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; THEVITIA PERUVIANA EXTRACT; UNCLASSIFIED DRUG;

APOCYNACEAE; AQUEOUS SOLUTION; ARGEMONE MEXICANA; ARTICLE; BIOCHEMISTRY; CALOTROPIS PROCERA; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DATURA; DATURA METAL; ENZYME ACTIVITY; ENZYME INHIBITION; ERYTHROCYTE MEMBRANE; FLOWER; FRUIT; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; NEUROTRANSMISSION; NONHUMAN; NORMAL HUMAN; PLANT LEAF; PLANT STEM; THEVITIA PERUVIANA; ULTRAVIOLET SPECTROPHOTOMETRY;

ACETYLCHOLINESTERASE; ARGEMONE; CALOTROPIS; CELLS, CULTURED; ENZYME ACTIVATION; ERYTHROCYTE MEMBRANE; HUMANS; PLANT EXTRACTS;

ARGEMONE MEXICANA; CALOTROPIS PROCERA; CANNABIS SATIVA; DATURA;

EID: 84872484521     PISSN: 01455680     EISSN: 1165158X     Source Type: Journal    
DOI: 10.1170/T936     Document Type: Article

References (75)

1. Akharaiyi, F.C., Antibacterial, Phytochemical and Antioxidant activities of Datura metel. Int. J. Pharm. Tech. Res. 2011, 3(1): 478-483.
2. Andrade, M. T., Lima, J. A., Pinto, A. C., Rezende, C. M., Carvalho, M. P. and Epifanio, R. A., Indole alkaloids from Tabernaemontana australis (Mü ell. Arg) Miers that inhibit acetylcholinesterase enzyme. Bioorg. Med. Chem. 2005, 13: 4092-4095.
3. Anonymous, Compendium of Pharmaceuticals and Specialties, 25th ed. 2000. Canadian Pharmacists Association, Toronto, Canada.
4. Bose, S., Mukherjee, B. and Dutta, S.K., Phytochemical investigation of fresh flower extract of Calotropis procera. Int. J. Pharmac. Sci. Res. 2010, 1 (12): 182-187.
5. Bott, C. and Bishop, D., Frequently Asked Questions About Cannabis. The Eldorado County Chapter of The American Alliance for Medical Cannabis. 2008.
6. Callahan, J.F. and Kruckenberg, S.M., Erythrocyte cholinesterase activity of domestic and laboratory animals: normal levels for nine species. Am. J. Vet. Res. 1967, 28: 1509-1512.
7. Chaudhuri, R.H.N., Pharmacognostic studies on the roots of Calotropis gigantea R.Br.ex Ait. Bull Bot Surv India. 1961, 3: 171- 173.
8. Choudhary, M.I., Yousuf, S., Nawas, S.A., Ahmed, S. and Atta-ur-Rahman, Cholinesterase inhibiting withanolides from Withania somnifera. Chem. Pharm. Bull. 2004, 52: 1358-1361.
9. Dalvi, R. R., Sanguinarine: its potential, as a liver toxic alkaloid present in the seeds of Argemone mexicana. Cell. Mol. Life Sci. 1985, 41 (1 ): 77-78.
10. Dash, G. K. and Murthy, P. N., Evaluation of Argemone mexicana Linn. Leaves for wound healing activity. J. Nat. Prod. Plant Resour. 2011, 1 (1): 46-56.
11. Devasari, T., Toxic effects of Calotropis procera. Indian J. Pharmacol. 1965, 27:272-5.
12. Dodge, J. T., Mitchel, C. and Hanakan, D. J., The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes. Arch. Biochem. Biophys. 1963, 100, 119-130.
13. Ellman, G.L., Courtney, K.D., Andres, V. and Featherstone, R.M., A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem. Pharmacol. 1961, 7:88-95.
14. Elsohly, M. A., Turner, C. E. and Pheobe, C. H., Anhydrocannabisativine, a New Alkaloid from Cannabis sativa. J. Pharmacy Pharm. Sci.1978, 67: 124.
15. Felger, R. S. and Moser, M. B. People of the Desert and Sea. Tucson, AZ: University of Arizona Press. 1985.
16. Flores-Sanchez, I. J. and Verpoorte, R., Secondary Metabolism in Cannabis. Phytochem. 2008.7: 615-639.
17. Galehr, O. and Plattner, F., tber das Schicksal des Acetylcholins im Blute. PflUgers Arch. Ges. Physiol. 1928, 218, 488-505.
18. Heinrich, M. and Teoh, H.L., Galanthamine from snowdrop-the development of a modern drug against Alzheimer's disease from local Caucasian knowledge. J. Ethnopharmacol. 2004, 92: 147-162.
19. Heller, M. and Hanahan, D. J., Human erythrocyte membrane bound enzyme: acetylcholinesterase. Biochim. Biophys. Acta. 1972, 255: 251-272.
20. Ingkaninan, K., Temkitthawon, P., Chuenchon, K., Yuyaem, T. and Thongnoi, W., Screening for acetylcholinesterase inhibitory activity in plants used in Thai traditional rejuvenating and neurotonic remedies. J. Ethnopharmacol. 2003, 89: 261-264.
21. Izzo, A.A., Carlo, D., Biscardi, G., Fusco, D., Mascolo, R., Borreli, N., Capasso, F., Fasulo, F. and Autore, M.P., Biological screening of Italian medicinal plants for antibacterial activity. Phytother. 1995, 9: 281-286.
22. Julian, P. L. and Pikl, J., Studies in the Indole Series. V. The Complete Synthesis of Physostigmine (Eserine). J. Am. Chem. Soc. 1935, 51: 755-757.
23. Kumar, V.L. and Arya, S., Medicinal uses and pharmacological properties of Calotropis procera . Recent Progress in Medicinal Plants.Houston, Tex, USA: Studium Press. 2006, 11: 373-388.
24. Lone, T. A. and Lone, R. A., Extraction of cannabinoids from Cannabis sativa L plant and its potential antimicrobial activity. Universal J. Med. Dentistry. 2012, 1(4):051-055.
25. Lowry, O.H., Rojenbrough, N.J., Farr, A.L. and Randall R.J., Protein measurement with the Folin phenol reagent. J.Biol.Chem.1951, 193: 265-275.
26. Matsumura, H., Matsuoka, M., Igisu, H. and Ikeda, M., Cooperative inhibition of acetylcholinesterase activities by hexachlorophene in human erythrocytes. Arch. Toxicol (1997) 71: 151- 156.
27. Mukherjeea, P. K., Kumarb, V., Malb, M. and Houghtona, P. J., Acetylcholinesterase inhibitors from plants, Phytomedicine. 2007, 14: 289-300.
28. Ott, P., Membrane acetylcholinesterases. Purification, molecular properties and interactions with amphiphilic environments. Biochim. Biophys. Acta . 1985, 822: 375-392.
29. Park , C. H., Kim, S., Choi, W., Lee, Y.J., Kim, J.S., Kang, S. S. and Suh, Y.H., Novel anticholinesterase and antiamnestic activities of dehydroevodiamine, a constituent of Evodia rutaecarpa. Planta Med. 1996, 62: 405-409.
30. Perry, N. S. L., Houghton, P. J., Theobald, A., Jenner, P. and Perry EK, In vitro inhibition of human erythrocyte acetylcholinesterase by Salvia lavandulaefolia essential oil and constituent terpenes. J. Pharmacy Pharmacol. 2000, 52: 895-902.
31. Rahman, A.U., Choudhary, M.I., Bioactive natural products as a potential source of new pharmacophores a theory of memory. Pure Appl. Chem. 2001, 73, 555-560.
32. Rajesh, Sharma, G.L., Studies on antimycotic properties of Datura metel. J Ethnopharmacol. 2002, 80(2-3):193-7.
33. Rhee,I.K., Meent, M. V. D., Ingkaninan, K. and Verpoorte R., Screening for acetylcholinesterase inhibitors from Amaryllidaceae using silica gel thin-layer chromatography in combination with bioactivity staining, J. Chromatography A. 2001, 915: 217-223.
34. Sakthivadive, M. and Thilagavathy, D., Larvicidal and chemosterilant activity of the acetone fraction of petroleum ether extract from Argemone mexicana L. seed. Biores. Tech. 2003, 89(2): 213-216.
35. Sharma, R. K., Chatterji, S, Rai, D. K., Mehta, S, Rai, P. K, Singh, R. K. Watal, G and Sharma B. Antioxidant activity and phenolics contents of the aqueous extracts of some Indian medicinal plants. J. Medicinal Plant Res.2009, 3(11): 9442-948.
36. Shaukat, S.S., Siddiqui, I. A., Khan, G. H. and Zaki, M.J., Nematicidal and allelopathic potential of Argemone mexicana, a tropical weed. Plant Soil. 2002, 245: 239-247.
37. Singh, S. and Singh, D. K. , Effect of active molluscicidal components of Abrus precatorius, Argemone mexicana and Nerium indicum on certain enzymes in the nervous system of lymnaea acuminate. J. Sci. I. R. Iran. 2000, 11: 3.
38. Slatkin, D.J., Doorenbos, N.J. and Harris, L.S., Chemical Constituents of Cannabis sativa L. root. J. Pharmacy Pharmeceutical Sci. 1971, 60: 1891-1892.
39. Sood, N.N., Mahipal, S., Sachdev, Mohan, M., Gupta, S.K. and Sachdev, H.P.S., Epidemic dropsy following transcutaneous absorption of Argemone mexicana oil. Trans. R. Soc. Trop. Med. Hyg.1985, 79 (4) : 510-512.
40. Srivastava, G. N., Chakravarti, R. N. and Zaidi, S. H., Studies on anticoagulant therapy. III. In vitro screening of some Indian plant for fibrinolytic and anticoagulant activity. Indian J. Med. Sci. 1962, 16: 873.
41. The Wealth of India. Publications and Information Directorate, Council of Scientific and Industrial Research, New Delhi, 1952, vol. III, Reprint 1988; p 17.
42. Tildesley, N.T.J., Kennedy, D.O., Perry, E.K., Ballard, C.G., Savelev, S.,Wesnes, K.A., Scholey, A.B., Salvia lavandulaefolia (Spanish sage) enhances memory in healthy young volunteers. Pharmacol. Biochem Behavior. 2003, 75: 669-674.
43. Tiwari, P., Kumar, B., Kaur, M., Kaur,G., and Kaur., H., Phytochemical screening and Extraction: A Review. Internationale Pharmaceutica Sciencia. 2011, 1: 98-106.
44. Turner, C. E., Elsohly, M. A. and Boeren, E.G., Constituests of Cannaabis sativa l. xvii.:Review of the Natural Constituents, J. Natural Products. 1980, 43: 2.
45. Vaidyaratnam PS. Varier's Arya Vaidya Sala - Indian Medicinal Plants. A Compendium of 500 species, Vol. 4, Vaidyarantum PS. Orient Longman, Chennai, India, 1994; p 126-130.
46. Wannang, N.N., Ndukwe, H.C. and Nnabuife, C., Evaluation of the analysis properties of the Datura metel seeds aqueous extracts. J. Med. Plants Res. 2009, 3(4) : 192-195.
47. Zuardi, A.W., Crippa, J.A.S., Hallak, J.E.C., Moreira, F.A. and Guimarães, F.S., Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug. Braz. J. Med. Biol. Res. 2006, 39: 4.
48. Singh, M. P., and Kumar, V., Biodegradation of vegetable and agrowastes by Pleurotus sapidus: A noble strategy to produce mushroom with enhanced yield and nutrition. Cell. Mol. Biol. 2012, 58 (1): 1-7.
49. Pandey, V. K., Singh, M.P., Srivastava, A. K., Vishwakarma S. K., and Takshak, S., Biodegradation of sugarcane bagasse by white rot fungus Pleurotus citrinopileatus. Cell. Mol. Biol. 2012, 58 (1): 8-14.
50. Ruhal, A., Rana, J. S., Kumar S., and Kumar, A., Immobilization of malate dehydrogenase on carbon nanotubes for development of malate biosensor. Cell. Mol. Biol. 2012, 58 (1): 15-20.
51. Vishwakarma, S. K., Singh, M. P., Srivastava A. K. and Pandey, V. K., Azo dye (direct blue) decolorization by immobilized extracellular enzymes of Pleurotus species. Cell. Mol. Biol. 2012, 58 (1): 21-25.
52. Dash, S. K., Sharma, M., Khare, S. and Kumar, A., rmpM gene as a genetic marker for human bacterial meningitis. Cell. Mol. Biol. 2012, 58 (1): 26-30.
53. Bertoletti, F., Crespan, E. and Maga, G., Tyrosine kinases as essential cellular cofactors and potential therapeutic targets for human immunodeficiency virus infection. Cell. Mol. Biol. 2012, 58 (1): 31-43.
54. Sandalli, C., Singh, K., and Modak, M. J., Characterization of catalytic carboxylate triad in non-replicative DNA polymerase III (pol E) of Geobacillus kaustophilus HTA. Cell. Mol. Biol. 2012, 58 (1): 44-49.
55. Kaushal, A., Kumar, D., Khare, S. and Kumar, A., speB gene as a specific genetic marker for early detection of rheumatic heart disease in human. Cell. Mol. Biol. 2012, 58 (1): 50-54.
56. Datta, J. and Lal, N., Application of molecular markers for genetic discrimination of fusarium wilt pathogen races affecting chickpea and pigeonpea in major regions of India. Cell. Mol. Biol. 2012, 58 (1): 55-65.
57. Siddiqi, N. J., Alhomida, A. S., Khan, A. H. and Onga, W. Y., Study on the distribution of different carnitine fractions in various tissues of bovine eye. Cell. Mol. Biol. 2012, 58 (1): 66-70.
58. Ong, Y. T., Kirby, K. A., Hachiya, A., Chiang, L. A., Marchand, B., Yoshimura, K., Murakami, T., Singh, K., Matsushita, S. and Sarafianos, S. G., Preparation of biologically active single-chain variable antibody fragments that target the HIV-1 GP120 v3 loop. Cell. Mol. Biol. 2012, 58 (1): 71-79.
59. Singh, J., Gautam, S. and Bhushan Pant, A., Effect of UV-B radiation on UV absorbing compounds and pigments of moss and lichen of Schirmacher Oasis region, East Antarctica. Cell. Mol. Biol. 2012, 58 (1): 80-84.
60. Singh, V. P., Srivastava, P. K., and Prasad, S. M., Impact of low and high UV-B radiation on the rates of growth and nitrogen metabolism in two cyanobacterial strains under copper toxicity. Cell. Mol. Biol. 2012, 58 (1): 85-95.
61. Datta, J. and Lal, N., Temporal and spatial changes in phenolic compounds in response Fusarium wilt in chickpea and pigeonpea. Cell. Mol. Biol. 2012, 58 (1): 96-102.
62. Sharma, R. K., Jaiswal, S. K., Siddiqi, N. J., and Sharma, B., Effect of carbofuran on some biochemical indices of human erythrocytes in vitro. Cell. Mol. Biol. 2012, 58 (1): 103-109.
63. Singh, A. K., Singh, S. and Singh, M. P., Bioethics A new frontier of biological Science. Cell. Mol. Biol. 2012, 58 (1): 110-114.
64. Adedeji, A. O., Singh, K. and Sarafianos, S. G., Structural and biochemical basis for the difference in the helicase activity of two different constructs of SARS-CoV helicase. Cell. Mol. Biol. 2012, 58 (1): 115-121.
65. Singh, S., Choudhuri, G., Kumar, R. and Agarwal, S., Association of 5, 10-methylenetetrahydrofolate reductase C677T polymorphism in susceptibility to tropical chronic pancreatitis in North Indian population. Cell. Mol. Biol. 2012, 58 (1): 122-127.
66. Sharma, R. K., Rai, K. D. and Sharma, B., In vitro carbofuran induced micronucleus formation in human blood lymphocytes. Cell. Mol. Biol. 2012, 58 (1): 128-133.
67. Naraian, R., Ram, S., Kaistha S. D. and Srivastava J., Occurrence of plasmid linked multiple drug resistance in bacterial isolates of tannery effluent. Cell. Mol. Biol. 2012, 58 (1): 134-141.
68. Pandey, A. K., Mishra, A. K., And Mishra, A., Antifungal and antioxidative potential of oil and extracts, respectively derived from leaves of Indian spice plant Cinnamomum tamala. Cell. Mol. Biol. 2012, 58 (1): 142-147.
69. Mishra, N., and Rizvi, S. I., Quercetin modulates na/k atpase and sodium hydrogen exchanger in type 2 diabetic erythrocytes. Cell. Mol. Biol. 2012, 58 (1): 148-152.
70. Kumar, A., Sharma, B. and Pandey, R. S., Assessment of stress in effect to pyrethroid insecticides, λ-cyhalothrin and cypermethrin in a freshwater fish, Channa punctatus (Bloch). Cell. Mol. Biol. 2012, 58 (1): 153-159.
71. Singh, M.P., Pandey, A. K., Vishwakarma S. K., Srivastava, A. K. and Pandey, V. K., Extracellular Xylanase Production by Pleurotus species on Lignocellulosic Wastes under in vivo Condition using Novel Pretreatment. Cell. Mol. Biol. 2012, 58 (1): 170-173.
72. Kumar, S., Sharma, U. K., Sharma, A. K., Pandey, A. K., Protective efficacy of Solanum xanthocarpum root extracts against free radical damage: phytochemical analysis and antioxidant effect. Cell. Mol. Biol. 2012, 58 (1): 174-181.
73. Shukla, A., Singh, A., Singh, A., Pathak, L.P., Shrivastava, N., Tripathi, P. K., Singh, K. and Singh, M.P., Inhibition of P. falciparum pfATP6 by curcumin and its derivatives: A bioinformatic Study. Cell. Mol. Biol. 2012, 58 (1): 182-186.
74. Michailidis, E., Singh, K., Ryan, E. M., Hachiya, A., Ong, Y. T., Kirby, K. A., Marchand, B., Kodama, E. N., Mitsuya, H., Parniak, M.A. and Sarafianos, S.G., Effect of translocation defective reverse transcriptase inhibitors on the activity of n348i, a connection subdomain drug resistant HIV-1 reverse transcriptase mutant. Cell. Mol. Biol. 2012, 58 (1): 187-195.
75. Parveen, A., Rizvi, S. H. M., Gupta, A., Singh, R., Ahmad, I., Mahdi, F., and Mahdi, A. A., NMR-based metabonomics study of sub-acute hepatotoxicity induced by silica nanoparticles in rats after intranasal exposure. Cell. Mol. Biol. 2012, 58 (1): 196-203.