Solventless dry powder coating for sustained drug release using mechanochemical treatment based on the tri-component system of acetaminophen, carnauba wax and glidant

Drug Development and Industrial Pharmacy

Volumn 39, Issue 2, 2013, Pages 259-265

  Hoashi, Yohei ^a,b   Tozuka, Yuichi ^b   Takeuchi, Hirofumi ^b  

^a Nipro Corporation   (Japan)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Carnauba wax; Dry powder coating; Glidant; Mechanochemical reaction; Mechanofusion; Solventless; Sustained release

Indexed keywords

CARNAUBA WAX; GLIDING AGENT; PARACETAMOL; TALC; UNCLASSIFIED DRUG; WAX;

ARTICLE; DRUG COATING; DRUG SOLUBILITY; DRY POWDER; ROTATION; SCANNING ELECTRON MICROSCOPY; SUSTAINED DRUG RELEASE;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; EXCIPIENTS; MICROSCOPY, ELECTRON, SCANNING; POWDERS; WAXES;

EID: 84872477365     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2012.673625     Document Type: Article

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