Investigation of the extent of surface coating via mechanofusion with varying additive levels and the influences on bulk powder flow properties

International Journal of Pharmaceutics

Volumn 413, Issue 1-2, 2011, Pages 36-43

  Zhou, Qi ^a   Qu, Li ^a   Gengenbach, Thomas ^b   Denman, John A ^c   Larson, Ian ^a   Stewart, Peter J ^a   Morton, David A V ^a  

^a MONASH UNIVERSITY   (Australia)

^b CSIRO   (Australia)

^c UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

Author keywords

Fine cohesive lactose powder; Magnesium stearate; Mechanical dry coating; Mechanofusion; Powder flow properties; Surface analysis

Indexed keywords

ALPHA LACTOSE; LACTOSE; MAGNESIUM STEARATE;

ARTICLE; CHEMICAL COMPOSITION; CONTROLLED STUDY; DRUG COATING; FLOW KINETICS; MORPHOLOGY; POWDER; PRIORITY JOURNAL; SURFACE PROPERTY;

COATED MATERIALS, BIOCOMPATIBLE; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; EXCIPIENTS; LACTOSE; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; PHOTOELECTRON SPECTROSCOPY; POWDERS; SPECTROMETRY, MASS, SECONDARY ION; STEARIC ACIDS; SURFACE PROPERTIES;

EID: 79957978481     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.04.014     Document Type: Article

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