Additive inhibition of human α1β2γ2 GABAA receptors by mixtures of commonly used drugs of abuse

NeuroToxicology

Volumn 35, Issue 1, 2013, Pages 23-29

  Hondebrink, Laura ^a   Tan, Sijie ^b   Hermans, Elise ^b   van Kleef, Regina G D M ^b   Meulenbelt, Jan ^a,b   Westerink, Remco H S ^b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Additivity; Cocaine; Intoxication; MCPP; MDA; MDMA

Indexed keywords

(3 CHLOROPHENYL)PIPERAZINE; 3,4 METHYLENEDIOXYMETHAMPHETAMINE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1BETA2 GAMMA2; COCAINE; UNCLASSIFIED DRUG;

ARTICLE; COMBINATION CHEMOTHERAPY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EXPOSURE; DRUG MECHANISM; DRUG POTENTIATION; DRUG RECEPTOR BINDING; EVOKED RESPONSE; MONOTHERAPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; XENOPUS;

3,4-METHYLENEDIOXYAMPHETAMINE; ANIMALS; COCAINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GABA ANTAGONISTS; HUMANS; MEMBRANE POTENTIALS; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; OOCYTES; PATCH-CLAMP TECHNIQUES; PIPERAZINES; RECEPTORS, GABA-A; XENOPUS LAEVIS;

EID: 84872458060     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2012.12.003     Document Type: Article

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