Cocaine and lidocaine have additive inhibitory effects on the GABA(A) current of acutely dissociated hippocampal pyramidal neurons

Brain Research

Volumn 821, Issue 1, 1999, Pages 26-32

  Ye, Jiang Hong ^a   Ren, Jun ^a   Krnjević, Kresimir ^b   Liu, Philip L ^a   McArdle, Joseph J ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Aminobutyric acid receptor channel; Freshly isolated neuron; Patch clamp; Seizure; Whole cell GABA(A), current

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; COCAINE; LIDOCAINE; TETRODOTOXIN;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ABUSE; DRUG POTENTIATION; HIPPOCAMPUS; NEWBORN; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SEIZURE;

ANESTHETICS, COMBINED; ANIMALS; COCAINE; DRUG INTERACTIONS; GAMMA-AMINOBUTYRIC ACID; LIDOCAINE; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SODIUM CHANNELS;

EID: 0345298279     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)01372-9     Document Type: Article

References (55)

1. G.J. Alexander, L.M. Kopeloff, Audiogenic seizures in mice: influence of agents affecting brain serotonin, Res. Commun. Chem. Pathol. Pharmacol. 14 (1976) 437-448.
2. B.K. Allredge, D.H. Lowenstein, P.P. Simon, Seizures associated with recreational drug abuse, Neurology 39 (1989) 1037-1039.
3. M.I. Arufe-Martinez, J.L. Romero-Palanco, Identification of cocaine in cocaine-lidocaine mixtures ('rock cocaine') and other illicit cocaine preparations using derivative absorption spectroscopy, J. Anal. Toxicol. 12 (1988) 192-196.
4. S.A. Barat, M.S. Abdel-Rahman, Cocaine and lidocaine in combination are synergistic convulsants, Brain Res. 742 (1996) 157-162.
5. K. Bates, Medical risks of cocaine use, West. J. Med. 148 (1988) 440-444.
6. J. Bose, Cocaine intoxication and its demoralizing effects, Br. Med. J. 2 (1902) 1020-1022.
7. J.K. Brown, M.H. Malone, Status of drug quality in the street-drug market-an update, Clinical Toxicology 9 (1976) 145-186.
8. J.F. Butterworth, G.R. Strichartz, Molecular mechanisms of local anesthesia: a review, Anesthesiology 72 (1990) 711-734.
9. D.L. Cameron, J.T. Williams, Cocaine inhibits GABA release in the VTA through endogenous 5-HT, J. Neurosci. 14 (1994) 6763-6767.
10. M. Chong-Kwong, R.B. Lipton, Seizures in hospitalized cocaine users, Neurology 39 (1989) 425-427.
11. E.G. Covino, Local anesthesia, New Engl. J. Med. 286 (1972) 975-1042.
12. L.L. Cregler, H. Mark, Medical complications of cocaine abuse, New Engl. J. Med. 315 (1986) 1495-1500.
13. 3H]batrachotoxin-A 20 alpha-benzoate binding in avesicular preparation from guinea pig cerebral cortex, Mol. Pharmacol. 23 (1983) 350-358.
14. E.E. Cunningham, R.C. Venuto, M.A. Zielezny, Adulterants in heroin/cocaine: implications concerning heroin-associated nephropathy, Drug Alcohol Depend. 14 (1984) 19-22.
15. C.M. de Fiebre, J.A. Ruth, A.C. Collins, Differential sensitivity of long-sleep and short-sleep mice to high doses of cocaine, Pharmacol. Biochem. Behav. 34 (1989) 887-893.
16. R. de Jong, Clinical physiology of local anesthetic action, in: M. Cousins, P. Bridenbaugh (Eds.), Neural Blockade in Clinical Anesthesia and Management of Pain, J.B. Lippincott, Philadelphia, PA, 1980, pp. 21-44.
17. R. Derlet, T.E. Alberton, Diazepam in the prevention of seizures and death in cocaine intoxicated rats, Ann. Emerg. Med. 18 (1989) 542-597.
18. R.W. Derlet, T.E. Albertson, Acute cocaine toxicity: antagonism by agents interacting with adrenoceptors, Pharmacol. Biochem. Behav. 36 (1990) 225-231.
19. R.W. Derlet, T.E. Albertson, Anticonvulsant modification of cocaine-induced toxicity in the rat, Neuropharmacology 29 (1990) 255-259.
20. R.W. Derlet, T.E. Albertson, R.S. Tharratt, Lidocaine potentiation of cocaine toxicity, Ann. Emerg. Med. 20 (1991) 135-138.
21. R.W. Derlet, T.E. Albertson, Flumazenil induces seizures and death in mixed cocaine-diazepam intoxication, Ann. Emerg. Med. 23 (1994) 494-498.
22. M.P. Earnest, Seizures, Neurol. Clin. 11 (1993) 563-575.
23. H.C. Farrar, G.L. Kearns, Cocaine: clinical pharmacology and toxicology, J. Pediatr. 115 (1989) 665-675.
24. B.S. Finkle, K.L. McCloskey, The forensic toxicology of cocaine, in: R.C. Petersen, R. Stillman (Eds.), National Institute on Drug Abuse Research Monograph 13, Chapter VIII, Rockville, MD, 1977.
25. W. Fischer, R. Bodewei, G. Satzinger, Anticonvulsant and sodium channel blocking effects of ralitoline in different screening models, Naunyn-Schmiedeberg's Arch. Pharmacol. 346 (1992) 442-452.
26. O.P. Hamill, A. Marty, E. Neher, B. Sakmann, F.J. Sigworth, Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches, Pflügers Arch. 391 (1981) 85-100.
27. M. Hara, Y. Kai, Y. Ikemoto, Local anesthetics reduce the inhibitory neurotransmitter-induced current in dissociated hippocampal neurons of the rat, Eur. J. Pharmacol. 283 (1995) 83-89.
28. C.R. Houser, GABA neurons in seizure disorders: a review of immunocytochemical studies, Neurochem. Res. 16 (1991) 295-308.
29. M. Ikeda, T. Dohi, A. Tsumasaki, Protection from local anesthetic-induced convulsions by γ-aminobutyric acid, Anesthesiology 56 (1982) 365-368.
30. P.W. Kalivas, P. Duffy, D1 receptors modulate glutamate transmission in the ventral tegmental area, J. Neurosci., 15 (1995) 5379-3788.
31. B. Khodorov, Some aspects of the pharmacology of sodium channels in nerve membrane. Process of inactivation, Biochem. Pharmacol. 28 (1979) 1451-1459.
32. K. Krnjević, GABA-mediated inhibitory mechanisms in relation to epileptic discharges, in: H.H. Jasper, N.M. vand Gelder (Eds.), Basic mechanisms of neuronal hyperexcitability, Alan R. Liss, New York, 1983, pp. 249-280.
33. K. Krnjevic, S. Schwartz, Is γ-aminobutyric acid an inhibitory transmitter?, Nature 211 (1966) 1372-1374.
34. D. Liu, R.J. Hariman, J.L. Bauman, Cocaine concentration-effect relationship in the presence and absence of lidocaine: evidence of competitive binding between cocaine and lidocaine, J. Pharmacol. Exp. Ther. 276 (1996) 568-577.
35. K.A. Loper, Clinical toxicity of cocaine, Med. Toxicol. Adverse Drug Exp. 4 (1989) 174-185.
36. A receptor channels, Annu. Rev. Neurosci. 17 (1994) 569-602.
37. S.T. Mason, M.E. Corcoran, Catecholamines and convulsions, Brain Res. 170 (1979) 497-507.
38. J.C. Matthews, A. Collins, Interactions of cocaine and cocaine congeners with sodium channels, Biochem. Pharmacol. 32 (1983) 455-460.
39. R.E. Mittleman, C.V. Wetli, Death caused by recreational cocaine use, J. Am. Med. Assoc. 252 (1984) 1889-1893.
40. J.A. Myers, M.P. Earnest, Generalized seizures and cocaine abuse, Neurology 34 (1984) 675-676.
41. G.R. Nakamura, T.T. Noguchi, Fatalities from cocaine overdoses in Los Angeles county, Clinical Toxicology 18 (1981) 895-905.
42. A. Pascual-Leone, A. Dhuna, I. Altafullah, D.C. Anderson, Cocaine-induced seizures, Neurology 40 (1990) 404-407.
43. E. Pulay, Cocaine poisoning, J. Am. Med. Assoc. 78 (1922) 1855.
44. J.M. Ritchie, N.M. Green, Local anesthetics, in: A.G. Gilman, L.S. Goodman, T.W. Rail, F. Murad, (Eds.), The Pharmacological Basic of Therapeutics, MacMillan, NY, 1985, pp. 302-321.
45. M.C. Ritz, F.R. George, Cocaine-induced seizures and lethality appear to be associated with distinct central nervous system binding sites, J. Phamacol. Exp. Ther. 264 (1993) 1333-1343.
46. M.C. Ritz, R.J. Lamb, S.R. Goldberg, M.J. Kuhar, Cocaine receptors on dopamine transporter are related to self-administration of cocaine, Science 237 (1987) 1219-1223.
47. K. Shimosato, S. Watanabe, R.J. Marley, T. Saito, Increased polyamine levels and changes in the sensitivity to convulsions during chronic treatment with cocaine in mice, Brain Res. 684 (1995) 243-247.
48. K. Tanaka, M. Yamasaki, Blocking of cortical inhibitory synapses by intravenous lidocaine, Nature 209 (1966) 207-208.
49. C.C. Tseng, R.W. Derlet, T.E. Albertson, Acute cocaine toxicity: the effect of agents in non-seizure-induced death, Pharmacol. Biochem. Behav. 46 (1993) 61-65.
50. J.E. Warnick, R.D. Kee, G.K.W. Yim, The effects of lidocaine on inhibition in the cerebral cortex, Anesthesiology 34 (1971) 327-332.
51. A.M. Washton, A. Tatarsky, Adverse effects of cocaine abuse, NIDA Res. Monogr. 49 (1984) 247-254.
52. S.R. Weiss, R.M. Post, F. Szele, R. Woodward, J. Nierenberg, Chronic carbamazepine inhibits the development of local anesthetic seizures kindled by cocaine and lidocaine, Brain Res. 497 (1989) 72-79.
53. J.H. Ye, P.L. Liu, W.-H. Wu, J.J. McArdle, Cocaine depresses GABAA current of hippocampal neurons, Brain Res. 770 (1997) 169-175.
54. Y. Zhu, W.B. Im, R.A. Lewis, F.F. Von Voigtlander, Comparison of pyrrolidinyl and piperidinyl benzamides for their anticonvulsant activity and inhibitory action on sodium channel, Br. J. Pharmacol. 106 (1992) 49-54.
55. Y. Zhu, W.B. Im, R.A. Lewis, J.S. Althaus, A.R. Cazers, J.W. Nielsen, J.R. Palmer, F.F. Von Voigtlander, Two metabolites of anticonvulsant U-5449A: their anticonvulsant activity and interaction with sodium channel, Brain Res. 606 (1993) 50-55.