Efficient access to peptidyl-RNA conjugates for picomolar inhibition of non-ribosomal FemXWv aminoacyl transferase

Chemistry - A European Journal

Volumn 19, Issue 4, 2013, Pages 1357-1363

  Fonvielle, Matthieu ^a,b   Mellal, Dénia ^c   Patin, Delphine ^d   Lecerf, Maxime ^a,b   Blanot, Didier ^d   Bouhss, Ahmed ^d   Santarem, Marco ^c   Mengin Lecreulx, Dominique ^d   Sollogoub, Matthieu ^c   Arthur, Michel ^a,b   Ethève Quelquejeu, Mélanie ^c  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b INSERM   (France)

^c Université Pierre et Marie Curie   (France)

^d INSTITUTE FOR INTEGRATIVE BIOLOGY OF THE CELL I2BC   (France)

Author keywords

click chemistry; inhibitors; peptidyl RNA conjugates; RNA; transferases

Indexed keywords

AMINOACYL; AZIDE-ALKYNE CYCLOADDITION; CLICK CHEMISTRY; CONVERGENT SYNTHESIS; DEOXYADENOSINE; DINUCLEOTIDES; PEPTIDOGLYCAN PRECURSORS; PEPTIDOGLYCANS; PEPTIDYL-RNA CONJUGATES; PHOSPHORAMIDITES; TRANSFERASES;

ACETYLENE; CORROSION INHIBITORS; CYCLOADDITION; ENZYMES; SYNTHESIS (CHEMICAL);

RNA;

AMINOACYLTRANSFERASE; COPPER; DRUG DERIVATIVE; OLIGOPEPTIDE; RNA; RNA LIGASE; UDP N ACETYLMURAMIC ACID PENTAPEPTIDE; UDP-N-ACETYLMURAMIC ACID PENTAPEPTIDE; URIDINE DIPHOSPHATE N ACETYLMURAMIC ACID;

ARTICLE; CATALYSIS; CHEMISTRY; CYCLOADDITION; DRUG ANTAGONISM; KINETICS; METABOLISM; PROTEIN BINDING; SYNTHESIS;

AMINOACYLTRANSFERASES; CATALYSIS; COPPER; CYCLOADDITION REACTION; KINETICS; OLIGOPEPTIDES; PROTEIN BINDING; RNA; RNA LIGASE (ATP); URIDINE DIPHOSPHATE N-ACETYLMURAMIC ACID;

EID: 84872433098     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201201999     Document Type: Article

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