Voltammetry coupled to mass spectrometry in the presence of isotope 18O labeled water for the prediction of oxidative transformation pathways of activated aromatic ethers: Acebutolol

Analytica Chimica Acta

Volumn 762, Issue , 2013, Pages 39-46

  Bussy, Ugo ^a   Tea, Illa ^a   Ferchaud Roucher, Véronique ^a   Krempf, Michel ^a   Silvestre, Virginie ^a   Galland, Nicolas ^a   Jacquemin, Denis ^a,b   Andresen Bergström, Moa ^c   Jurva, Ulrik ^c   Boujtita, Mohammed ^a  

^a UNIVERSITÉ DE NANTES   (France)

^b INSTITUT UNIVERSITAIRE DE FRANCE   (France)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

Acebutolol; EC MS; Mass voltammetry; O Dealkylation; Prediction of oxidative metabolism

Indexed keywords

ACEBUTOLOL; EC-MS; MASS-VOLTAMMETRY; O-DEALKYLATION; OXIDATIVE METABOLISM;

AROMATIZATION; DENSITY FUNCTIONAL THEORY; ELECTROCHEMICAL OXIDATION; ETHERS; HYDROLYSIS; ISOTOPES; MASS SPECTROMETRY; VOLTAMMETRY;

AROMATIC COMPOUNDS;

ACEBUTOLOL; AROMATIC COMPOUND; ETHER DERIVATIVE; ISOTOPE; OXYGEN 18; WATER;

AEROBIC METABOLISM; ANALYTIC METHOD; ARTICLE; CHEMICAL REACTION; DEALKYLATION; DENSITY FUNCTIONAL THEORY; DRUG DETERMINATION; DRUG HYDROLYSIS; DRUG STRUCTURE; ELECTROCHEMICAL ANALYSIS; ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; POTENTIOMETRY; PREDICTION; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

EID: 84872412937     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2012.12.002     Document Type: Article

References (37)

1. Regino M.C.S., Brajter-Toth A. Anal. Chem. 1997, 69:5067-5072.
2. Jahn S., Karst U. J. Chromatogr. A 2012, 1259:16-49.
3. Gun J., Bharathi S., Gutkin V., Rizkov D., Voloshenko A., Shelkov R., Sladkevich S., Kyi N., Rona M., Wolanov Y., Rizkov D., Koch M., Mizrahi S., Pridkhochenko P.V., Modestov A., Lev O. Isr. J. Chem. 2010, 50:360-373.
4. Chen L., Hofmann D., Klumpp E., Xiang X., Chen Y., Küppers S. Chemosphere 2012, 10.1016/j.chemosphere.2012.05.105.
5. Van Leeuwen S.M., Blankert B., Kauffmann J.-M., Karst U. Anal. Bioanal. Chem. 2005, 382:742-750.
6. Looi D.-W., Eyler J.R., Brajter-Toth A. Electrochim. Acta 2011, 56:2633-2640.
7. Skopalova J., Vacek J., Papouskova B., Jirovsky D., Maier V., Ranc V. Bioelectrochemistry 2012, 87:15-20.
8. Jurva U., Wikstrom H.V., Weidolf L., Bruins A.P. Rapid Commun. Mass Spectrom. 2003, 17:800-810.
9. Johansson T., Weidolf L., Jurva U. Rapid Commun. Mass Spectrom. 2007, 21:2323-2331.
10. Madsen K.G., Olsen J., Skonberg C., Hansen S.H., Jurva U. Chem. Res. Toxicol. 2007, 20:821-831.
11. Jurva U., Wikstrom H.V., Bruins A.P. Rapid Commun. Mass Spectrom. 2000, 15:677-678.
12. Faber H., Jahn S., Kunnemeyer J., Simon H., Melles D., Vogel M., Karst U. Angew. Chem. Int. Ed. Engl. 2011, 50:A52-A58.
13. Lohmann W., Doetzer R., Guetter G., Van L.S.M., Karst U. J. Am. Soc. Mass Spectrom. 2009, 20:138-145.
14. Lohmann W., Karst U. Anal. Bioanal. Chem. 2009, 394:1341-1348.
15. Baumann A., Faust A., Law M.P., Kuhlmann M.T., Kopka K., Schaefers M., Karst U. Anal. Chem. 2011, 83:5415-5421.
16. Nouri-Nigjeh E., Bischoff R., Bruins A.P., Permentier H.P. Curr. Drug Metab. 2011, 12:359-371.
17. Johansson T., Weidolf L., Castagnoli J.N., Jurva U. Rapid Commun. Mass Spectrom. 2010, 24:1231-1240.
18. Lohmann W., Karst U. Anal. Bioanal. Chem. 2008, 391:79-96.
19. Nouri-Nigjeh E., Bischoff R., Bruins A.P., Permentier H.P. Analyst 2011, 136:5064-5067.
20. Nouri-Nigjeh E., Permentier H.P., Bischoff R., Bruins A.P. Anal. Chem. 2011, 83:5519-5525.
21. Pujos E., Cren-Olive C., Paisse O., Flament-Waton M.M., Grenier-Loustalot M.F. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2009, 877:4007-4014.
22. Bussy U., Ferchaud-Roucher V., Tea I., Krempf M., Silvestre V., Boujtita M. Electrochim. Acta 2012, 69:351-357.
23. Li X., Zhu D., You T. Electrophoresis 2011, 32:2139-2147.
24. Abdellatef H.E., El-Henawee M.M., El-Sayed H.M., Ayad M.M. Spectrochim. Acta Part A 2006, 65A:997-999.
25. El Dawy M.A., Mabrouk M.M., El Barbary R.A. Chem. Pharm. Bull. 2006, 54:1026-1029.
26. Brzezinska E., Stolarska J. J. Planar Chromatogr. Mod. TLC 2005, 18:443-449.
27. Jiang H., Randlett C., Junga H., Jiang X., Ji Q.C. J. Chromatogr. B 2009, 877:173-180.
28. Al-Ghamdi A.F., Hefnawy M.M., Al-Majed A.A., Belal F.F. Chem. Cent. J 2012, 6:15.
29. M.J.e.a. Frisch, Gaussian 09 Revision A.02 Gaussian Inc., Wallingford CT (2009).
30. Boese A.D., Martin J.M.L. J. Chem. Phys. 2004, 121:3405-3416.
31. Marenich A.V., Cramer C.J., Truhlar D.G. J. Phys. Chem. B 2009, 113:6378-6396.
32. Reed A.E., Curtiss L.A., Weinhold F. Chem. Rev. 1988, 88:899-926.
33. Lohmann W., Karst U. Anal. Bioanal. Chem. 2006, 386:1701-1708.
34. Zatloukalová M., Křen V., GaŽák R., Kubala M., Trouillas P., Ulrichová J., Vacek J. Bioelectrochemistry 2011, 82:117-124.
35. Trouillas P., Marsal P., Svobodova A., Vostalova J., Gazak R., Hrbac J., Sedmera P., Kren V., Lazzaroni R., Duroux J.-L., Walterova D. J. Phys. Chem. A 2008, 112:1054-1063.
36. Davis B.D.A.F.T. Drug Metab. Dispos. 1979, 79:360-365.
37. Maurer H.H., Tenberken O., Kratzsch C., Weber A.A., Peters F.T. J. Chromatogr. A 2004, 1058:169-181.