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Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 3, 2009, Pages 173-180

Using supported liquid extraction together with cellobiohydrolase chiral stationary phases-based liquid chromatography with tandem mass spectrometry for enantioselective determination of acebutolol and its active metabolite diacetolol in spiked human plasma

(5) Jiang, Hongliang a Randlett, Christopher a Junga, Heiko a Jiang, Xiangyu a Ji, Qin C a

a 206 Carnegie Center (United States)

Author keywords

Acebutolol; Cellobiohydrolase (CBH); Chiral separation; Diacetolol; Supported liquid extraction (SLE)

Indexed keywords

ACEBUTOLOL; CELLOBIOHYDROLASE (CBH); CHIRAL SEPARATION; DIACETOLOL; SUPPORTED LIQUID EXTRACTION (SLE);

CHIRALITY; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; CUSTOMER SATISFACTION; ENANTIOMERS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; PLASMA (HUMAN); PLASMAS; QUALITY ASSURANCE; QUALITY FUNCTION DEPLOYMENT; SEPARATION; SOLVENT EXTRACTION; TOTAL QUALITY MANAGEMENT;

EXTRACTION;

ACEBUTOLOL; CELLULOSE 1,4 BETA CELLOBIOSIDASE; DIACETOLOL;

ARTICLE; DRUG BONE LEVEL; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

ACEBUTOLOL; ADRENERGIC BETA-ANTAGONISTS; CELLULOSE 1,4-BETA-CELLOBIOSIDASE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; HUMANS; LEAST-SQUARES ANALYSIS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM; TANDEM MASS SPECTROMETRY;

EID: 58149202063 PISSN: 15700232 EISSN: None Source Type: Journal
DOI: 10.1016/j.jchromb.2008.12.006 Document Type: Article

Times cited : (36)

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