메뉴 건너뛰기




Volumn 37, Issue 2, 2013, Pages 201-203

The role of T-cells in the pathogenesis of myelodysplastic syndromes: Passengers and drivers

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; INFLIXIMAB; INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 7 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; T LYMPHOCYTE RECEPTOR; TALMAPIMOD; THALIDOMIDE;

EID: 84872412514     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2012.11.007     Document Type: Letter
Times cited : (29)

References (28)
  • 2
    • 1042303646 scopus 로고    scopus 로고
    • Evolution of clonal cytogenetic abnormalities in aplastic anemia
    • Maciejewski J.P., Selleri C. Evolution of clonal cytogenetic abnormalities in aplastic anemia. Leuk Lymphoma 2004, 45:433-440.
    • (2004) Leuk Lymphoma , vol.45 , pp. 433-440
    • Maciejewski, J.P.1    Selleri, C.2
  • 4
    • 0025868236 scopus 로고
    • The occurrence subtype and significance of haemopoietic inhibitory T cells (HIT cells) in myelodysplasia: an in vitro study
    • Smith M.A., Smith J.G. The occurrence subtype and significance of haemopoietic inhibitory T cells (HIT cells) in myelodysplasia: an in vitro study. Leuk Res 1991, 15:597-601.
    • (1991) Leuk Res , vol.15 , pp. 597-601
    • Smith, M.A.1    Smith, J.G.2
  • 5
    • 84859584423 scopus 로고    scopus 로고
    • Are T-cell dysfunctions the other side of the moon in the pathogenesis of myelodysplastic syndromes?
    • Fozza C., Longinotti M. Are T-cell dysfunctions the other side of the moon in the pathogenesis of myelodysplastic syndromes?. Eur J Haematol 2012, 88:380-387.
    • (2012) Eur J Haematol , vol.88 , pp. 380-387
    • Fozza, C.1    Longinotti, M.2
  • 6
    • 0034782479 scopus 로고    scopus 로고
    • Oligoclonal T cell expansion in myelodysplastic syndrome: evidence for an autoimmune process
    • Epperson D.E., Nakamura R., Saunthararajah Y., Melenhorst J., Barrett A.J. Oligoclonal T cell expansion in myelodysplastic syndrome: evidence for an autoimmune process. Leuk Res 2001, 25:1075-1083.
    • (2001) Leuk Res , vol.25 , pp. 1075-1083
    • Epperson, D.E.1    Nakamura, R.2    Saunthararajah, Y.3    Melenhorst, J.4    Barrett, A.J.5
  • 7
    • 67650065350 scopus 로고    scopus 로고
    • Patients with myelodysplastic syndromes display several T-cell expansions, which are mostly polyclonal in the CD4(+) subset and oligoclonal in the CD8(+) subset
    • Fozza C., Contini S., Galleu A., et al. Patients with myelodysplastic syndromes display several T-cell expansions, which are mostly polyclonal in the CD4(+) subset and oligoclonal in the CD8(+) subset. Exp Hematol 2009, 37:947-955.
    • (2009) Exp Hematol , vol.37 , pp. 947-955
    • Fozza, C.1    Contini, S.2    Galleu, A.3
  • 8
    • 33947388858 scopus 로고    scopus 로고
    • Prevalence and clinical association of clonal T-cell expansions in myelodysplastic syndrome
    • Epling-Burnette P.K., Painter J.S., Rollison D.E., et al. Prevalence and clinical association of clonal T-cell expansions in myelodysplastic syndrome. Leukemia 2007, 21:659-667.
    • (2007) Leukemia , vol.21 , pp. 659-667
    • Epling-Burnette, P.K.1    Painter, J.S.2    Rollison, D.E.3
  • 9
    • 23044473715 scopus 로고    scopus 로고
    • Preferential suppression of trisomy 8 compared with normal hematopoietic cell growth by autologous lymphocytes in patients with trisomy 8 myelodysplastic syndrome
    • Sloand E.M., Mainwaring L., Fuhrer M., et al. Preferential suppression of trisomy 8 compared with normal hematopoietic cell growth by autologous lymphocytes in patients with trisomy 8 myelodysplastic syndrome. Blood 2005, 106:841-851.
    • (2005) Blood , vol.106 , pp. 841-851
    • Sloand, E.M.1    Mainwaring, L.2    Fuhrer, M.3
  • 10
    • 84864390842 scopus 로고    scopus 로고
    • Apoptotic cells and clonally expanded cytotoxic T cells in bone marrow trephines of patients with myelodysplastic syndrome
    • Pülhorn H., Herrmann M., Harms H., Jung A., Baumann I. Apoptotic cells and clonally expanded cytotoxic T cells in bone marrow trephines of patients with myelodysplastic syndrome. Histopathology 2012, 61:200-211.
    • (2012) Histopathology , vol.61 , pp. 200-211
    • Pülhorn, H.1    Herrmann, M.2    Harms, H.3    Jung, A.4    Baumann, I.5
  • 11
    • 41949110665 scopus 로고    scopus 로고
    • The clinical significance of activated lymphocytes in patients with myelodysplastic syndromes: a single centre study of 131 patients
    • Meers S., Vandenberghe P., Boogaerts M., Verhoef G., Delforge M. The clinical significance of activated lymphocytes in patients with myelodysplastic syndromes: a single centre study of 131 patients. Leuk Res 2008, 32:1026-1035.
    • (2008) Leuk Res , vol.32 , pp. 1026-1035
    • Meers, S.1    Vandenberghe, P.2    Boogaerts, M.3    Verhoef, G.4    Delforge, M.5
  • 12
    • 77249097478 scopus 로고    scopus 로고
    • Host immunity affects survival in myelodysplastic syndromes: independent prognostic value of the absolute lymphocyte count
    • Jacobs N.L., Holtan S.G., Porrata L.F., Markovic S.N., Tefferi A., Steensma D.P. Host immunity affects survival in myelodysplastic syndromes: independent prognostic value of the absolute lymphocyte count. Am J Hematol 2010, 85:160-163.
    • (2010) Am J Hematol , vol.85 , pp. 160-163
    • Jacobs, N.L.1    Holtan, S.G.2    Porrata, L.F.3    Markovic, S.N.4    Tefferi, A.5    Steensma, D.P.6
  • 13
    • 34547957665 scopus 로고    scopus 로고
    • CD4+CD25 high Foxp3+ regulatory T cells in myelodysplastic syndrome (MDS)
    • Kordasti S.Y., Ingram W., Hayden J., et al. CD4+CD25 high Foxp3+ regulatory T cells in myelodysplastic syndrome (MDS). Blood 2007, 110:847-850.
    • (2007) Blood , vol.110 , pp. 847-850
    • Kordasti, S.Y.1    Ingram, W.2    Hayden, J.3
  • 14
    • 33947505084 scopus 로고    scopus 로고
    • T-cell receptor repertoire usage after allografting differs between CD4+CD25+ regulatory T-cells and their CD4+CD25- counterpart
    • Fozza C., Nadal E., Longinotti M., Dazzi F. T-cell receptor repertoire usage after allografting differs between CD4+CD25+ regulatory T-cells and their CD4+CD25- counterpart. Haematologica 2007, 92:206-214.
    • (2007) Haematologica , vol.92 , pp. 206-214
    • Fozza, C.1    Nadal, E.2    Longinotti, M.3    Dazzi, F.4
  • 15
    • 62549141807 scopus 로고    scopus 로고
    • Kinetics, function and bone marrow trafficking of CD4+CD25+FOXP3+ regulatory T cells in myelodysplastic syndromes (MDS)
    • Kotsianidis I., Bouchliou I., Nakou E., et al. Kinetics, function and bone marrow trafficking of CD4+CD25+FOXP3+ regulatory T cells in myelodysplastic syndromes (MDS). Leukemia 2009, 23:510-518.
    • (2009) Leukemia , vol.23 , pp. 510-518
    • Kotsianidis, I.1    Bouchliou, I.2    Nakou, E.3
  • 16
    • 72249104044 scopus 로고    scopus 로고
    • Immune dysregulation and dyserythropoiesis in the myelodysplastic syndromes
    • Alfinito F., Sica M., Luciano L., et al. Immune dysregulation and dyserythropoiesis in the myelodysplastic syndromes. Br J Haematol 2010, 148:90-98.
    • (2010) Br J Haematol , vol.148 , pp. 90-98
    • Alfinito, F.1    Sica, M.2    Luciano, L.3
  • 17
    • 84864824602 scopus 로고    scopus 로고
    • Patients with early-stage myelodysplastic syndromes show increased frequency of CD4+CD25+CD127 (low) regulatory T cells
    • Fozza C., Longu F., Contini S., et al. Patients with early-stage myelodysplastic syndromes show increased frequency of CD4+CD25+CD127 (low) regulatory T cells. Acta Haematol 2012, 128:178-182.
    • (2012) Acta Haematol , vol.128 , pp. 178-182
    • Fozza, C.1    Longu, F.2    Contini, S.3
  • 18
    • 84866152555 scopus 로고    scopus 로고
    • Expansion of effector memory regulatory T cells represents a novel prognostic factor in lower risk myelodysplastic syndrome
    • Mailloux A.W., Sugimori C., Komrokji R.S., et al. Expansion of effector memory regulatory T cells represents a novel prognostic factor in lower risk myelodysplastic syndrome. J Immunol 2012, 189:3198-3208.
    • (2012) J Immunol , vol.189 , pp. 3198-3208
    • Mailloux, A.W.1    Sugimori, C.2    Komrokji, R.S.3
  • 19
    • 61849168098 scopus 로고    scopus 로고
    • IL-17-producing CD4(+) T cells, pro-inflammatory cytokines and apoptosis are increased in low risk myelodysplastic syndrome
    • Kordasti S.Y., Afzali B., Lim Z., et al. IL-17-producing CD4(+) T cells, pro-inflammatory cytokines and apoptosis are increased in low risk myelodysplastic syndrome. Br J Haematol 2009, 145:64-72.
    • (2009) Br J Haematol , vol.145 , pp. 64-72
    • Kordasti, S.Y.1    Afzali, B.2    Lim, Z.3
  • 20
    • 79955949689 scopus 로고    scopus 로고
    • Th17 and Foxp3(+) T regulatory cell dynamics and distribution in myelodysplastic syndromes
    • Bouchliou I., Miltiades P., Nakou E., et al. Th17 and Foxp3(+) T regulatory cell dynamics and distribution in myelodysplastic syndromes. Clin Immunol 2011, 139:350-359.
    • (2011) Clin Immunol , vol.139 , pp. 350-359
    • Bouchliou, I.1    Miltiades, P.2    Nakou, E.3
  • 21
    • 83655161382 scopus 로고    scopus 로고
    • Patients with myelodysplastic syndromes show reduced frequencies of CD4(+) CD8(+) double-positive T cells
    • Fozza C., Contini S., Virdis P., et al. Patients with myelodysplastic syndromes show reduced frequencies of CD4(+) CD8(+) double-positive T cells. Eur J Haematol 2012, 88:89-90.
    • (2012) Eur J Haematol , vol.88 , pp. 89-90
    • Fozza, C.1    Contini, S.2    Virdis, P.3
  • 22
    • 7344223859 scopus 로고    scopus 로고
    • Haematological response of patients with myelodysplastic syndrome to antithymocyte globulin is associated with a loss of lymphocyte-mediated inhibition of CFU-GM and alterations in T-cell receptor Vbeta profiles
    • Molldrem J.J., Jiang Y.Z., Stetler-Stevenson M., Mavroudis D., Hensel N., Barrett A.J. Haematological response of patients with myelodysplastic syndrome to antithymocyte globulin is associated with a loss of lymphocyte-mediated inhibition of CFU-GM and alterations in T-cell receptor Vbeta profiles. Br J Haematol 1998, 102:1314-1322.
    • (1998) Br J Haematol , vol.102 , pp. 1314-1322
    • Molldrem, J.J.1    Jiang, Y.Z.2    Stetler-Stevenson, M.3    Mavroudis, D.4    Hensel, N.5    Barrett, A.J.6
  • 23
    • 4544273958 scopus 로고    scopus 로고
    • Remicade as TNF suppressor in patients with myelodysplastic syndromes
    • Raza A., Candoni A., Khan U., et al. Remicade as TNF suppressor in patients with myelodysplastic syndromes. Leuk Lymphoma 2004, 45:2099-2104.
    • (2004) Leuk Lymphoma , vol.45 , pp. 2099-2104
    • Raza, A.1    Candoni, A.2    Khan, U.3
  • 24
    • 33845474265 scopus 로고    scopus 로고
    • Inhibition of overactivated p38 MAPK can restore hematopoiesis in myelodysplastic syndrome progenitors
    • Navas T.A., Mohindru M., Estes M., et al. Inhibition of overactivated p38 MAPK can restore hematopoiesis in myelodysplastic syndrome progenitors. Blood 2006, 10:4170-4177.
    • (2006) Blood , vol.10 , pp. 4170-4177
    • Navas, T.A.1    Mohindru, M.2    Estes, M.3
  • 25
    • 0031888417 scopus 로고    scopus 로고
    • Cyclosporin A therapy in hypoplastic MDS patients and certain refractory anaemias without hypoplastic bone marrow
    • Jonásova A., Neuwirtová R., Cermák J., et al. Cyclosporin A therapy in hypoplastic MDS patients and certain refractory anaemias without hypoplastic bone marrow. Br J Haematol 1998, 100:304-309.
    • (1998) Br J Haematol , vol.100 , pp. 304-309
    • Jonásova, A.1    Neuwirtová, R.2    Cermák, J.3
  • 26
    • 69249220181 scopus 로고    scopus 로고
    • A clinical and immunologic phase 2 trial of Wilms tumor gene product 1 (WT1) peptide vaccination in patients with AML and MDS
    • Keilholz U., Letsch A., Busse A., et al. A clinical and immunologic phase 2 trial of Wilms tumor gene product 1 (WT1) peptide vaccination in patients with AML and MDS. Blood 2009, 113:6541-6548.
    • (2009) Blood , vol.113 , pp. 6541-6548
    • Keilholz, U.1    Letsch, A.2    Busse, A.3
  • 27
    • 79953100658 scopus 로고    scopus 로고
    • T-cell immune responses to Wilms tumor 1 protein in myelodysplasia responsive to immunosuppressive therapy
    • Sloand E.M., Melenhorst J.J., Tucker Z.C., et al. T-cell immune responses to Wilms tumor 1 protein in myelodysplasia responsive to immunosuppressive therapy. Blood 2011, 117:2691-2699.
    • (2011) Blood , vol.117 , pp. 2691-2699
    • Sloand, E.M.1    Melenhorst, J.J.2    Tucker, Z.C.3
  • 28
    • 81255136909 scopus 로고    scopus 로고
    • Survival benefits from reduced-intensity conditioning in allogeneic stem cell transplantation for young lower-risk MDS patients without significant comorbidities
    • Lee S.E., Kim Y.J., Yahng S.A., et al. Survival benefits from reduced-intensity conditioning in allogeneic stem cell transplantation for young lower-risk MDS patients without significant comorbidities. Eur J Haematol 2011, 87:510-520.
    • (2011) Eur J Haematol , vol.87 , pp. 510-520
    • Lee, S.E.1    Kim, Y.J.2    Yahng, S.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.