메뉴 건너뛰기




Volumn 87, Issue 6, 2011, Pages 510-520

Survival benefits from reduced-intensity conditioning in allogeneic stem cell transplantation for young lower-risk MDS patients without significant comorbidities

Author keywords

Myeloablative conditioning; Myelodysplastic syndrome; Reduced intensity conditioning; Stem cell transplantation

Indexed keywords

AZACITIDINE;

EID: 81255136909     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2011.01697.x     Document Type: Article
Times cited : (21)

References (40)
  • 1
    • 13444269356 scopus 로고    scopus 로고
    • Myelodysplastic syndromes - coping with ineffective hematopoiesis
    • Cazzola M, Malcovati L. Myelodysplastic syndromes - coping with ineffective hematopoiesis. N Engl J Med 2005;352:536-8.
    • (2005) N Engl J Med , vol.352 , pp. 536-538
    • Cazzola, M.1    Malcovati, L.2
  • 2
    • 55049105415 scopus 로고    scopus 로고
    • Changing the treatment paradigm in myelodysplastic syndromes
    • Mufti GJ, Chen TL. Changing the treatment paradigm in myelodysplastic syndromes. Cancer Control 2008;15(Suppl):14-28.
    • (2008) Cancer Control , vol.15 , Issue.SUPPL. , pp. 14-28
    • Mufti, G.J.1    Chen, T.L.2
  • 3
    • 34548219420 scopus 로고    scopus 로고
    • Time-dependent prognostic scoring system for predicting survival and leukemic evolution in myelodysplastic syndromes
    • Malcovati L, Germing U, Kuendgen A, et al. Time-dependent prognostic scoring system for predicting survival and leukemic evolution in myelodysplastic syndromes. J Clin Oncol 2007;25:3503-10.
    • (2007) J Clin Oncol , vol.25 , pp. 3503-3510
    • Malcovati, L.1    Germing, U.2    Kuendgen, A.3
  • 4
    • 0030897009 scopus 로고    scopus 로고
    • International scoring system for evaluating prognosis in myelodysplastic syndromes
    • Greenberg P, Cox C, LeBeau MM, et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 1997;89:2079-88.
    • (1997) Blood , vol.89 , pp. 2079-2088
    • Greenberg, P.1    Cox, C.2    LeBeau, M.M.3
  • 5
    • 3142580475 scopus 로고    scopus 로고
    • A decision analysis of allogeneic bone marrow transplantation for the myelodysplastic syndromes: delayed transplantation for low-risk myelodysplasia is associated with improved outcome
    • Cutler CS, Lee SJ, Greenberg P, et al. A decision analysis of allogeneic bone marrow transplantation for the myelodysplastic syndromes: delayed transplantation for low-risk myelodysplasia is associated with improved outcome. Blood 2004;104:579-85.
    • (2004) Blood , vol.104 , pp. 579-585
    • Cutler, C.S.1    Lee, S.J.2    Greenberg, P.3
  • 6
    • 58249126355 scopus 로고    scopus 로고
    • The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of myelodysplastic syndromes: an evidence-based review
    • Oliansky DM, Antin JH, Bennett JM, et al. The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of myelodysplastic syndromes: an evidence-based review. Biol Blood Marrow Transplant 2009;15:137-72.
    • (2009) Biol Blood Marrow Transplant , vol.15 , pp. 137-172
    • Oliansky, D.M.1    Antin, J.H.2    Bennett, J.M.3
  • 7
    • 78149358704 scopus 로고    scopus 로고
    • The lower risk mds patient at risk of rapid progression
    • Mittelman M, Oster HS, Hoffman M, Neumann D. The lower risk mds patient at risk of rapid progression. Leuk Res 2010;34:1551-5.
    • (2010) Leuk Res , vol.34 , pp. 1551-1555
    • Mittelman, M.1    Oster, H.S.2    Hoffman, M.3    Neumann, D.4
  • 9
    • 8944243549 scopus 로고    scopus 로고
    • Factors influencing outcome in de novo myelodysplastic syndromes treated by allogeneic bone marrow transplantation: a long-term study of 71 patients societe francaise de greffe de moelle
    • Sutton L, Chastang C, Ribaud P, et al. Factors influencing outcome in de novo myelodysplastic syndromes treated by allogeneic bone marrow transplantation: a long-term study of 71 patients societe francaise de greffe de moelle. Blood 1996;88:358-65.
    • (1996) Blood , vol.88 , pp. 358-365
    • Sutton, L.1    Chastang, C.2    Ribaud, P.3
  • 10
    • 0031756617 scopus 로고    scopus 로고
    • Allogeneic bone marrow transplantation for myelodysplastic syndrome: outcomes analysis according to ipss score
    • Appelbaum FR, Anderson J. Allogeneic bone marrow transplantation for myelodysplastic syndrome: outcomes analysis according to ipss score. Leukemia 1998;12(Suppl 1):S25-9.
    • (1998) Leukemia , vol.12 , Issue.SUPPL. 1
    • Appelbaum, F.R.1    Anderson, J.2
  • 11
    • 50949133921 scopus 로고    scopus 로고
    • Who classification and wpss predict posttransplantation outcome in patients with myelodysplastic syndrome: a study from the gruppo italiano trapianto di midollo osseo (gitmo)
    • Alessandrino EP, Della Porta MG, Bacigalupo A, et al. Who classification and wpss predict posttransplantation outcome in patients with myelodysplastic syndrome: a study from the gruppo italiano trapianto di midollo osseo (gitmo). Blood 2008;112:895-902.
    • (2008) Blood , vol.112 , pp. 895-902
    • Alessandrino, E.P.1    Della Porta, M.G.2    Bacigalupo, A.3
  • 12
    • 77449147495 scopus 로고    scopus 로고
    • Allogeneic stem cell transplantation for patients with refractory anaemia with matched related and unrelated donors: delay of the transplant is associated with inferior survival
    • de Witte T, Brand R, van Biezen A, et al. Allogeneic stem cell transplantation for patients with refractory anaemia with matched related and unrelated donors: delay of the transplant is associated with inferior survival. Br J Haematol 2009;146:627-36.
    • (2009) Br J Haematol , vol.146 , pp. 627-636
    • de Witte, T.1    Brand, R.2    van Biezen, A.3
  • 13
    • 34250800831 scopus 로고    scopus 로고
    • Viewpoint: what is the role of allogeneic haematopoietic cell transplantation in the era of reduced-intensity conditioning - is there still an upper age limit? A focus on myeloid neoplasia
    • Finke J, Nagler A. Viewpoint: what is the role of allogeneic haematopoietic cell transplantation in the era of reduced-intensity conditioning - is there still an upper age limit? A focus on myeloid neoplasia. Leukemia 2007;21:1357-62.
    • (2007) Leukemia , vol.21 , pp. 1357-1362
    • Finke, J.1    Nagler, A.2
  • 14
    • 77952428379 scopus 로고    scopus 로고
    • Allogeneic hematopoietic stem-cell transplantation in aml and mds using myeloablative versus reduced-intensity conditioning: long-term follow-up
    • Shimoni A, Hardan I, Shem-Tov N, Yerushalmi R, Nagler A. Allogeneic hematopoietic stem-cell transplantation in aml and mds using myeloablative versus reduced-intensity conditioning: long-term follow-up. Leukemia 2010;24:1050-2.
    • (2010) Leukemia , vol.24 , pp. 1050-1052
    • Shimoni, A.1    Hardan, I.2    Shem-Tov, N.3    Yerushalmi, R.4    Nagler, A.5
  • 15
    • 34948869819 scopus 로고    scopus 로고
    • Comorbidity and disease status based risk stratification of outcomes among patients with acute myeloid leukemia or myelodysplasia receiving allogeneic hematopoietic cell transplantation
    • Sorror ML, Sandmaier BM, Storer BE, Maris MB, Baron F, Maloney DG, Scott BL, Deeg HJ, Appelbaum FR, Storb R. Comorbidity and disease status based risk stratification of outcomes among patients with acute myeloid leukemia or myelodysplasia receiving allogeneic hematopoietic cell transplantation. J Clin Oncol 2007;25:4246-54.
    • (2007) J Clin Oncol , vol.25 , pp. 4246-4254
    • Sorror, M.L.1    Sandmaier, B.M.2    Storer, B.E.3    Maris, M.B.4    Baron, F.5    Maloney, D.G.6    Scott, B.L.7    Deeg, H.J.8    Appelbaum, F.R.9    Storb, R.10
  • 16
    • 38349195008 scopus 로고    scopus 로고
    • Comparable non-relapse mortality and survival after hla-identical sibling blood stem cell transplantation with reduced or conventional-intensity preparative regimens for high-risk myelodysplasia or acute myeloid leukemia in first remission
    • Martino R, Valcarcel D, Brunet S, Sureda A, Sierra J. Comparable non-relapse mortality and survival after hla-identical sibling blood stem cell transplantation with reduced or conventional-intensity preparative regimens for high-risk myelodysplasia or acute myeloid leukemia in first remission. Bone Marrow Transplant 2008;41:33-8.
    • (2008) Bone Marrow Transplant , vol.41 , pp. 33-38
    • Martino, R.1    Valcarcel, D.2    Brunet, S.3    Sureda, A.4    Sierra, J.5
  • 17
    • 0037105538 scopus 로고    scopus 로고
    • Evidence for a graft-versus-leukemia effect after allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning in acute myelogenous leukemia and myelodysplastic syndromes
    • Martino R, Caballero MD, Perez-Simon JA, et al. Evidence for a graft-versus-leukemia effect after allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning in acute myelogenous leukemia and myelodysplastic syndromes. Blood 2002;100:2243-5.
    • (2002) Blood , vol.100 , pp. 2243-2245
    • Martino, R.1    Caballero, M.D.2    Perez-Simon, J.A.3
  • 18
    • 10744229703 scopus 로고    scopus 로고
    • Allogeneic stem cell transplantation after a fludarabine/busulfan-based reduced-intensity conditioning in patients with myelodysplastic syndrome or secondary acute myeloid leukemia
    • Kroger N, Bornhauser M, Ehninger G, et al. Allogeneic stem cell transplantation after a fludarabine/busulfan-based reduced-intensity conditioning in patients with myelodysplastic syndrome or secondary acute myeloid leukemia. Ann Hematol 2003;82:336-42.
    • (2003) Ann Hematol , vol.82 , pp. 336-342
    • Kroger, N.1    Bornhauser, M.2    Ehninger, G.3
  • 19
    • 10744222061 scopus 로고    scopus 로고
    • Hla-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative conditioning for patients with hematologic malignancies
    • Maris MB, Niederwieser D, Sandmaier BM, et al. Hla-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative conditioning for patients with hematologic malignancies. Blood 2003;102:2021-30.
    • (2003) Blood , vol.102 , pp. 2021-2030
    • Maris, M.B.1    Niederwieser, D.2    Sandmaier, B.M.3
  • 20
    • 39649115845 scopus 로고    scopus 로고
    • Hematopoietic cell transplantation specific comorbidity index as an outcome predictor for patients with acute myeloid leukemia in first remission: combined fhcrc and mdacc experiences
    • Sorror ML, Giralt S, Sandmaier BM, De Lima M, Shahjahan M, Maloney DG, Deeg HJ, Appelbaum FR, Storer B, Storb R. Hematopoietic cell transplantation specific comorbidity index as an outcome predictor for patients with acute myeloid leukemia in first remission: combined fhcrc and mdacc experiences. Blood 2007;110:4606-13.
    • (2007) Blood , vol.110 , pp. 4606-4613
    • Sorror, M.L.1    Giralt, S.2    Sandmaier, B.M.3    De Lima, M.4    Shahjahan, M.5    Maloney, D.G.6    Deeg, H.J.7    Appelbaum, F.R.8    Storer, B.9    Storb, R.10
  • 21
    • 18244407767 scopus 로고    scopus 로고
    • The effect of first-line imatinib interim therapy on the outcome of allogeneic stem cell transplantation in adults with newly diagnosed philadelphia chromosome-positive acute lymphoblastic leukemia
    • Lee S, Kim YJ, Min CK, Kim HJ, Eom KS, Kim DW, Lee JW, Min WS, Kim CC. The effect of first-line imatinib interim therapy on the outcome of allogeneic stem cell transplantation in adults with newly diagnosed philadelphia chromosome-positive acute lymphoblastic leukemia. Blood 2005;105:3449-57.
    • (2005) Blood , vol.105 , pp. 3449-3457
    • Lee, S.1    Kim, Y.J.2    Min, C.K.3    Kim, H.J.4    Eom, K.S.5    Kim, D.W.6    Lee, J.W.7    Min, W.S.8    Kim, C.C.9
  • 22
    • 33745755637 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (vegf) is associated with reduced severity of acute graft-versus-host disease and nonrelapse mortality after allogeneic stem cell transplantation
    • Min CK, Kim SY, Lee MJ, et al. Vascular endothelial growth factor (vegf) is associated with reduced severity of acute graft-versus-host disease and nonrelapse mortality after allogeneic stem cell transplantation. Bone Marrow Transplant 2006;38:149-56.
    • (2006) Bone Marrow Transplant , vol.38 , pp. 149-156
    • Min, C.K.1    Kim, S.Y.2    Lee, M.J.3
  • 23
    • 67349091502 scopus 로고    scopus 로고
    • Successful prevention of acute graft-versus-host disease using low-dose antithymocyte globulin after mismatched, unrelated, hematopoietic stem cell transplantation for acute myelogenous leukemia
    • Kim HJ, Min WS, Cho BS, et al. Successful prevention of acute graft-versus-host disease using low-dose antithymocyte globulin after mismatched, unrelated, hematopoietic stem cell transplantation for acute myelogenous leukemia. Biol Blood Marrow Transplant 2009;15:704-17.
    • (2009) Biol Blood Marrow Transplant , vol.15 , pp. 704-717
    • Kim, H.J.1    Min, W.S.2    Cho, B.S.3
  • 27
    • 19944433633 scopus 로고    scopus 로고
    • Conventional versus reduced-intensity conditioning regimen for allogeneic stem cell transplantation in patients with hematological malignancies
    • Valcarcel D, Martino R, Sureda A, et al. Conventional versus reduced-intensity conditioning regimen for allogeneic stem cell transplantation in patients with hematological malignancies. Eur J Haematol 2005;74:144-51.
    • (2005) Eur J Haematol , vol.74 , pp. 144-151
    • Valcarcel, D.1    Martino, R.2    Sureda, A.3
  • 28
    • 0037103191 scopus 로고    scopus 로고
    • Conditioning with targeted busulfan and cyclophosphamide for hemopoietic stem cell transplantation from related and unrelated donors in patients with myelodysplastic syndrome
    • Deeg HJ, Storer B, Slattery JT, et al. Conditioning with targeted busulfan and cyclophosphamide for hemopoietic stem cell transplantation from related and unrelated donors in patients with myelodysplastic syndrome. Blood 2002;100:1201-7.
    • (2002) Blood , vol.100 , pp. 1201-1207
    • Deeg, H.J.1    Storer, B.2    Slattery, J.T.3
  • 29
    • 77950432778 scopus 로고    scopus 로고
    • Reduced intensity conditioning regimen with fludarabine, busulfan, and low-dose tbi (flu-bu2-tbi): clinical efficacy in high-risk patients
    • Takahata M, Hashino S, Okada K, et al. Reduced intensity conditioning regimen with fludarabine, busulfan, and low-dose tbi (flu-bu2-tbi): clinical efficacy in high-risk patients. Am J Hematol 2010;85:243-8.
    • (2010) Am J Hematol , vol.85 , pp. 243-248
    • Takahata, M.1    Hashino, S.2    Okada, K.3
  • 30
    • 77956907211 scopus 로고    scopus 로고
    • Favorable outcomes of intravenous busulfan, fludarabine, and 400 cgy total body irradiation-based reduced-intensity conditioning allogeneic stem cell transplantation for acute myelogenous leukemia with old age and/or co-morbidities
    • Lee SE, Kim HJ, Min WS, et al. Favorable outcomes of intravenous busulfan, fludarabine, and 400 cgy total body irradiation-based reduced-intensity conditioning allogeneic stem cell transplantation for acute myelogenous leukemia with old age and/or co-morbidities. Int J Hematol 2010;92:342-50.
    • (2010) Int J Hematol , vol.92 , pp. 342-350
    • Lee, S.E.1    Kim, H.J.2    Min, W.S.3
  • 31
    • 27244435820 scopus 로고    scopus 로고
    • Comparison of 2 preparative regimens for stem cell transplantation from hla-matched sibling donors in patients with advanced myelodysplastic syndrome
    • Kim YJ, Kim DW, Lee S, et al. Comparison of 2 preparative regimens for stem cell transplantation from hla-matched sibling donors in patients with advanced myelodysplastic syndrome. Int J Hematol 2005;82:66-71.
    • (2005) Int J Hematol , vol.82 , pp. 66-71
    • Kim, Y.J.1    Kim, D.W.2    Lee, S.3
  • 32
    • 34548419737 scopus 로고    scopus 로고
    • The beneficial effect of chronic graft-versus-host disease on the clinical outcome of transplantation with fludarabine/busulfan-based reduced-intensity conditioning for patients with de novo myelodysplastic syndrome
    • Cho BS, Kim YJ, Cho SG, et al. The beneficial effect of chronic graft-versus-host disease on the clinical outcome of transplantation with fludarabine/busulfan-based reduced-intensity conditioning for patients with de novo myelodysplastic syndrome. Int J Hematol 2007;85:446-55.
    • (2007) Int J Hematol , vol.85 , pp. 446-455
    • Cho, B.S.1    Kim, Y.J.2    Cho, S.G.3
  • 33
    • 39149133203 scopus 로고    scopus 로고
    • Sustained remissions of high-risk acute myeloid leukemia and myelodysplastic syndrome after reduced-intensity conditioning allogeneic hematopoietic transplantation: chronic graft-versus-host disease is the strongest factor improving survival
    • Valcarcel D, Martino R, Caballero D, et al. Sustained remissions of high-risk acute myeloid leukemia and myelodysplastic syndrome after reduced-intensity conditioning allogeneic hematopoietic transplantation: chronic graft-versus-host disease is the strongest factor improving survival. J Clin Oncol 2008;26:577-84.
    • (2008) J Clin Oncol , vol.26 , pp. 577-584
    • Valcarcel, D.1    Martino, R.2    Caballero, D.3
  • 34
    • 70350121940 scopus 로고    scopus 로고
    • Reduced-intensity conditioning allogeneic stem cell transplantation is a potential therapeutic approach for adults with high-risk acute lymphoblastic leukemia in remission: results of a prospective phase 2 study
    • Cho BS, Lee S, Kim YJ, et al. Reduced-intensity conditioning allogeneic stem cell transplantation is a potential therapeutic approach for adults with high-risk acute lymphoblastic leukemia in remission: results of a prospective phase 2 study. Leukemia 2009;23:1763-70.
    • (2009) Leukemia , vol.23 , pp. 1763-1770
    • Cho, B.S.1    Lee, S.2    Kim, Y.J.3
  • 35
    • 33644967374 scopus 로고    scopus 로고
    • Myeloablative vs nonmyeloablative allogeneic transplantation for patients with myelodysplastic syndrome or acute myelogenous leukemia with multilineage dysplasia: a retrospective analysis
    • Scott BL, Sandmaier BM, Storer B, Maris MB, Sorror ML, Maloney DG, Chauncey TR, Storb R, Deeg HJ. Myeloablative vs nonmyeloablative allogeneic transplantation for patients with myelodysplastic syndrome or acute myelogenous leukemia with multilineage dysplasia: a retrospective analysis. Leukemia 2006;20:128-35.
    • (2006) Leukemia , vol.20 , pp. 128-135
    • Scott, B.L.1    Sandmaier, B.M.2    Storer, B.3    Maris, M.B.4    Sorror, M.L.5    Maloney, D.G.6    Chauncey, T.R.7    Storb, R.8    Deeg, H.J.9
  • 36
    • 33746661102 scopus 로고    scopus 로고
    • Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using hla-identical sibling donors in myelodysplastic syndromes
    • Martino R, Iacobelli S, Brand R, et al. Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using hla-identical sibling donors in myelodysplastic syndromes. Blood 2006;108:836-46.
    • (2006) Blood , vol.108 , pp. 836-846
    • Martino, R.1    Iacobelli, S.2    Brand, R.3
  • 37
    • 77955586814 scopus 로고    scopus 로고
    • Azacytidine treatment after discontinuation of immunosuppressants in patients with myelodysplastic syndrome and relapse after allo-sct at a single center
    • Kim SY, Cho SG, Cho BS, et al. Azacytidine treatment after discontinuation of immunosuppressants in patients with myelodysplastic syndrome and relapse after allo-sct at a single center. Bone Marrow Transplant 2010;45:1375-6.
    • (2010) Bone Marrow Transplant , vol.45 , pp. 1375-1376
    • Kim, S.Y.1    Cho, S.G.2    Cho, B.S.3
  • 38
    • 33845216261 scopus 로고    scopus 로고
    • Successful treatment of relapsed aml after allogeneic stem cell transplantation with azacitidine
    • Graef T, Kuendgen A, Fenk R, Zohren F, Haas R, Kobbe G. Successful treatment of relapsed aml after allogeneic stem cell transplantation with azacitidine. Leuk Res 2007;31:257-9.
    • (2007) Leuk Res , vol.31 , pp. 257-259
    • Graef, T.1    Kuendgen, A.2    Fenk, R.3    Zohren, F.4    Haas, R.5    Kobbe, G.6
  • 40
    • 79953708226 scopus 로고    scopus 로고
    • Impact of intensity of conditioning therapy in patients aged 40-60years with aml/myelodysplastic syndrome undergoing allogeneic transplantation
    • Khabori MA, El-Emary M, Xu W, Guyatt G, Galal A, Kuruvilla J, Lipton J, Messner H, Gupta V. Impact of intensity of conditioning therapy in patients aged 40-60years with aml/myelodysplastic syndrome undergoing allogeneic transplantation. Bone Marrow Transplant 2011;46:516-22.
    • (2011) Bone Marrow Transplant , vol.46 , pp. 516-522
    • Khabori, M.A.1    El-Emary, M.2    Xu, W.3    Guyatt, G.4    Galal, A.5    Kuruvilla, J.6    Lipton, J.7    Messner, H.8    Gupta, V.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.