Indexed keywords
ANTISENSE;
INTERCELLULAR ADHESION MOLECULE-1;
SMALL INTERFERING RNA;
THERAPEUTIC POTENTIALS;
TUMOR NECROSIS FACTORS;
CELL ADHESION;
ENDOTHELIAL CELLS;
GENE EXPRESSION;
MOLECULAR BIOLOGY;
MOLECULES;
RNA;
ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1;
INTERCELLULAR ADHESION MOLECULE 1;
SMALL INTERFERING RNA;
TUMOR NECROSIS FACTOR RECEPTOR 1;
ANTISENSE STRAND;
ARTICLE;
CONTROLLED STUDY;
ENDOTHELIUM CELL;
FLOW CYTOMETRY;
GENE SILENCING;
GENETIC TRANSFECTION;
HUMAN;
HUMAN CELL;
PRIORITY JOURNAL;
QUANTITATIVE ASSAY;
REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;
RNA STRUCTURE;
SENSE STRAND;
THERMOSTABILITY;
CODON;
E-SELECTIN;
ENDOTHELIAL CELLS;
HUMANS;
INTERCELLULAR ADHESION MOLECULE-1;
MODELS, BIOLOGICAL;
RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I;
RNA, SMALL INTERFERING;
TRANSFECTION;
TUMOR NECROSIS FACTOR-ALPHA;
VASCULAR CELL ADHESION MOLECULE-1;
1
0032545933
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
Fire A., et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998, 391:806-811.
(1998)
Nature
, vol.391
, pp. 806-811
Fire, A.1
2
1642346273
Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference
Ui-Tei K., et al. Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference. Nucleic Acids Research 2004, 32:936-948.
(2004)
Nucleic Acids Research
, vol.32
, pp. 936-948
Ui-Tei, K.1
3
1542336952
Rational siRNA design for RNA interference
Reynolds A., et al. Rational siRNA design for RNA interference. Nature Biotechnology 2004, 22:326-330.
(2004)
Nature Biotechnology
, vol.22
, pp. 326-330
Reynolds, A.1
4
79960038814
Chemical modification of small interfering RNA
Bramsen J.B., Kjems J. Chemical modification of small interfering RNA. Methods in Molecular Biology 2011, 721:77-103.
(2011)
Methods in Molecular Biology
, vol.721
, pp. 77-103
Bramsen, J.B.1
Kjems, J.2
5
10744225153
Asymmetry in the assembly of the RNAi enzyme complex
Schwarz D.S., et al. Asymmetry in the assembly of the RNAi enzyme complex. Cell 2003, 115:199-208.
(2003)
Cell
, vol.115
, pp. 199-208
Schwarz, D.S.1
6
0142165224
Functional siRNAs and miRNAs exhibit strand bias
Khvorova A., et al. Functional siRNAs and miRNAs exhibit strand bias. Cell 2003, 115:209-216.
(2003)
Cell
, vol.115
, pp. 209-216
Khvorova, A.1
7
27744590896
Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes
Matranga C., et al. Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell 2005, 123:607-620.
(2005)
Cell
, vol.123
, pp. 607-620
Matranga, C.1
8
15844371219
Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein
Ma J.B., et al. Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature 2005, 434:666-670.
(2005)
Nature
, vol.434
, pp. 666-670
Ma, J.B.1
9
15844402005
Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex
Parker J.S., et al. Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex. Nature 2005, 434:663-666.
(2005)
Nature
, vol.434
, pp. 663-666
Parker, J.S.1
10
8844271740
A protein sensor for siRNA asymmetry
Tomari Y., et al. A protein sensor for siRNA asymmetry. Science 2004, 306:1377-1380.
(2004)
Science
, vol.306
, pp. 1377-1380
Tomari, Y.1
11
40249106017
Knockdown of TNFR1 by the sense strand of an ICAM-1 siRNA: dissection of an off-target effect
Clark P.R., et al. Knockdown of TNFR1 by the sense strand of an ICAM-1 siRNA: dissection of an off-target effect. Nucleic Acids Research 2008, 36:1081-1097.
(2008)
Nucleic Acids Research
, vol.36
, pp. 1081-1097
Clark, P.R.1
12
28444437360
Suppression of ICAM-1 in human venous endothelial cells by small interfering RNAs
Walker T., et al. Suppression of ICAM-1 in human venous endothelial cells by small interfering RNAs. European Journal of Cardio-Thoracic Surgery 2005, 28:816-820.
(2005)
European Journal of Cardio-Thoracic Surgery
, vol.28
, pp. 816-820
Walker, T.1
13
0141750434
Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening
Aza-Blanc P., et al. Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening. Molecular Cell 2003, 12:627-637.
(2003)
Molecular Cell
, vol.12
, pp. 627-637
Aza-Blanc, P.1
14
33748701701
Computational models with thermodynamic and composition features improve siRNA design
Shabalina S.A., et al. Computational models with thermodynamic and composition features improve siRNA design. BMC Bioinform. 2006, 7:65.
(2006)
BMC Bioinform.
, vol.7
, pp. 65
Shabalina, S.A.1
15
34848926634
Improved silencing properties using small internally segmented interfering RNAs
Bramsen J.B., et al. Improved silencing properties using small internally segmented interfering RNAs. Nucleic Acids Research 2007, 35:5886-5897.
(2007)
Nucleic Acids Research
, vol.35
, pp. 5886-5897
Bramsen, J.B.1
16
38649099969
Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity
Chen P.Y., et al. Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity. RNA 2008, 14:263-274.
(2008)
RNA
, vol.14
, pp. 263-274
Chen, P.Y.1
17
66349108231
A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity
Bramsen J.B., et al. A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity. Nucleic Acids Research 2009, 37:2867-2881.
(2009)
Nucleic Acids Research
, vol.37
, pp. 2867-2881
Bramsen, J.B.1
18
82955250900
Efficient in vivo delivery of siRNA into brain capillary endothelial cells along with endogenous lipoprotein
Kuwahara H., et al. Efficient in vivo delivery of siRNA into brain capillary endothelial cells along with endogenous lipoprotein. Molecular Therapy 2011, 19:2213-2221.
(2011)
Molecular Therapy
, vol.19
, pp. 2213-2221
Kuwahara, H.1