Genetic susceptibility to pancreatic cancer and its functional characterisation: The PANcreatic Disease ReseArch (PANDoRA) consortium

Digestive and Liver Disease

Volumn 45, Issue 2, 2013, Pages 95-99

  Campa, Daniele ^a,b   Rizzato, Cosmeri ^a   Capurso, Gabriele ^b   Giese, Nathalia ^b,c   Funel, Niccola ^b,d   Greenhalf, William ^b,e   Soucek, Pavel ^b,f   Gazouli, Maria ^b,g   Pezzilli, Raffaele ^b,h   Pasquali, Claudio ^b,i   Talar Wojnarowska, Renata ^b,j   Cantore, Maurizio ^b,k   Andriulli, Angelo ^b,l   Scarpa, Aldo ^b,m   Jamroziak, Krzysztof ^b,j   Fave, Gianfranco Delle ^b   Costello, Eithne ^b,e   Khaw, Kay Tee ^b,n   Heller, Anette ^b,c   Key, Tim J ^b,o   Theodoropoulos, George ^b,g   Malecka Panas, Ewa ^b,j   Mambrini, Andrea ^b,k   Bambi, Franco ^b,p   Landi, Stefano ^b,m   Pedrazzoli, Sergio ^b,i   Bassi, Claudio ^b,q   Pacetti, Paola ^b,k   Piepoli, Ada ^b,l   Tavano, Francesca ^b,l   di Sebastiano, Pierluigi ^b,l   Vodickova, Ludmila ^b,r   Basso, Daniela ^b,s   Plebani, Mario ^b,s   Fogar, Paola ^b,s   Büchler, Markus W ^b,c   Bugert, Peter ^b,c   Vodicka, Pavel ^b,r   Boggi, Ugo ^b,d   Neoptolemos, John P ^b,e   Werner, J Jens ^b,c   Canzian, Federico ^a,b   Faveb, Gianfranco Delle ^b   more..

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d UNIVERSITY HOSPITAL OF PISA   (Italy)

^e National Institute for Health Research   (United Kingdom)

^f NATIONAL INSTITUTE OF PUBLIC HEALTH   (Czech Republic)

^g UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^h UNIVERSITY OF BOLOGNA   (Italy)

ⁱ UNIVERSITY OF PADOVA   (Italy)

^j MEDICAL UNIVERSITY OF LODZ   (Poland)

^k ASL1 Massa Carrara   (Italy)

^l CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^m UNIVERSITY AND HOSPITAL TRUST OF VERONA   (Italy)

ⁿ UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^o UNIVERSITY OF FLORENCE   (Italy)

^p UNIVERSITY OF PISA   (Italy)

^q CHARLES UNIVERSITY   (Czech Republic)

^r UNIVERSITY HOSPITAL OF PADOVA   (Italy)

^s UNIVERSITY OF OXFORD   (United Kingdom)

more..

Author keywords

Cancer susceptibility; Genetic polymorphisms; Genetic susceptibility; Pancreatic cancer

Indexed keywords

ADULT; ARTICLE; CANCER PROGNOSIS; CAUCASIAN; CHRONIC PANCREATITIS; CONTROLLED STUDY; FEMALE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PANCREAS CANCER; PANCREAS ISLET CELL TUMOR; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVAL; TREATMENT RESPONSE;

EID: 84872382315     PISSN: 15908658     EISSN: 18783562     Source Type: Journal    
DOI: 10.1016/j.dld.2012.09.014     Document Type: Article

References (35)

1. Ferlay J., Shin H.R., Bray F., et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. International Journal of Cancer 2010.
2. Jemal A., Siegel R., Ward E., et al. Cancer statistics, 2008. CA: A Cancer Journal for Clinicians 2008, 58:71-96.
3. Anderson K., Mack T., Silverman D. Cancer of the pancreas 2006, Oxford Univ. Press, New York.
4. Jacobs E.J., Chanock S.J., Fuchs C.S., et al. Family history of cancer and risk of pancreatic cancer: a pooled analysis from the Pancreatic Cancer Cohort Consortium (PanScan). International Journal of Cancer 2010, 127:1421-1428.
5. Hassan M.M., Bondy M.L., Wolff R.A., et al. Risk factors for pancreatic cancer: case-control study. American Journal of Gastroenterology 2007, 102:2696-2707.
6. Jones S., Hruban R.H., Kamiyama M., et al. Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. Science 2009, 324:p217.
7. Tischkowitz M.D., Sabbaghian N., Hamel N., et al. Analysis of the gene coding for the BRCA2-interacting protein PALB2 in familial and sporadic pancreatic cancer. Gastroenterology 2009, 137:1183-1186.
8. Amundadottir L., Kraft P., Stolzenberg-Solomon R.Z., et al. Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nature Genetics 2009, 41:986-990.
9. Petersen G.M., Amundadottir L., Fuchs C.S., et al. A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Nature Genetics 2010, 42:224-228.
10. Low S.K., Kuchiba A., Zembutsu H., et al. Genome-wide association study of pancreatic cancer in Japanese population. PLoS ONE 2010, 5:11824.
11. Wu C., Miao X., Huang L., et al. Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations. Nature Genetics 2011, 44:62-66.
12. Dong X., Li Y., Hess K.R., et al. DNA mismatch repair gene polymorphisms affect survival in pancreatic cancer. Oncologist 2011, 16:61-70.
13. Rizzato C., Campa D., Giese N., et al. Pancreatic cancer susceptibility loci and their role in survival. PLoS ONE 2011, 6:pe27921.
14. Talar-Wojnarowska R., Gasiorowska A., Olakowski M., et al. Role of cyclooxygenase-2 gene polymorphisms in pancreatic carcinogenesis. World Journal of Gastroenterology 2011, 17:4113-4117.
15. Tanaka M., Okazaki T., Suzuki H., et al. Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome. Cancer 2010, 117:744-751.
16. Naccarati A., Pardini B., Polakova V., et al. Genotype and haplotype analysis of TP53 gene and the risk of pancreatic cancer: an association study in the Czech Republic. Carcinogenesis 2010, 31:666-670.
17. Campa D., Husing A., Stein A., et al. Genetic variability of the mTOR pathway and prostate cancer risk in the European Prospective Investigation on Cancer (EPIC). PLoS ONE 2011, 6:pe16914.
18. Campa D., Kaaks R., Le Marchand L., et al. Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium. Journal of the National Cancer Institute 2011, 103:1252-1263.
19. Kote-Jarai Z., Olama A.A., Giles G.G., et al. Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nature Genetics 2011, 43:785-791.
20. Martino A., Sainz J., Buda G., et al. Genetics and molecular epidemiology of multiple myeloma: the rationale for the IMMEnSE consortium (review). International Journal of Oncology 2011, 40:625-638.
21. Day N., Oakes S., Luben R., et al. EPIC-Norfolk: study design and characteristics of the cohort European Prospective Investigation of Cancer. British Journal of Cancer 1999, 80(Suppl. 1):95-103.
22. Davey G.K., Spencer E.A., Appleby P.N., et al. EPIC-Oxford: lifestyle characteristics and nutrient intakes in a cohort of 33 883 meat-eaters and 31 546 non meat-eaters in the UK. Public Health Nutrition 2003, 6:259-269.
23. Chung C.C., Chanock S.J. Current status of genome-wide association studies in cancer. Human Genetics 2011.
24. Kim N.W., Piatyszek M.A., Prowse K.R., et al. Specific association of human telomerase activity with immortal cells and cancer. Science 1994, 266:2011-2015.
25. Hou L., Zhang X., Gawron A.J., et al. Surrogate tissue telomere length and cancer risk: shorter or longer?. Cancer Letters 2012, 319:130-135.
26. Wallace D.C. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annual Review of Genetics 2005, 39:359-407.
27. Wallace D.C. Bioenergetics and the epigenome: interface between the environment and genes in common diseases. Developmental Disabilities Research Reviews 2010, 16:114-119.
28. Yu M. Generation, function and diagnostic value of mitochondrial DNA copy number alterations in human cancers. Life Sciences 2011, 89:65-71.
29. Shen J., Platek M., Mahasneh A., et al. Mitochondrial copy number and risk of breast cancer: a pilot study. Mitochondrion 2011, 10:62-68.
30. Qu F., Liu X., Zhou F., et al. Association between mitochondrial DNA content in leukocytes and colorectal cancer risk: a case-control analysis. Cancer 2011, 117:3148-3155.
31. Bonner M.R., Shen M., Liu C.S., et al. Mitochondrial DNA content and lung cancer risk in Xuan Wei, China. Lung Cancer 2009, 63:331-334.
32. Lan Q., Lim U., Liu C.S., et al. A prospective study of mitochondrial DNA copy number and risk of non-Hodgkin lymphoma. Blood 2008, 112:4247-4249.
33. Ebner S., Lang R., Mueller E.E., et al. Mitochondrial haplogroups, control region polymorphisms and malignant melanoma: a study in middle European Caucasians. PLoS ONE 2011, 6:pe27192.
34. Lam E.T., Bracci P.M., Holly E.A., et al. Mitochondrial DNA sequence variation and risk of pancreatic cancer. Cancer Research 2012, 72:686-695.
35. Skonieczna K., Malyarchuk B.A., Grzybowski T. The landscape of mitochondrial DNA variation in human colorectal cancer on the background of phylogenetic knowledge. Biochimica et Biophysica Acta 2012, 1825:153-159.