GroESL overexpression imparts Escherichia coli tolerance to i-, n-, and 2-butanol, 1,2,4-butanetriol and ethanol with complex and unpredictable patterns

Metabolic Engineering

Volumn 15, Issue 1, 2013, Pages 196-205

  Zingaro, Kyle A ^a   Terry Papoutsakis, Eleftherios ^a  

^a University of Delaware   (United States)

Author keywords

Biofuels; Heat shock proteins; LogP; Molecular chaperones; Tolerance engineering

Indexed keywords

2-BUTANOL; ALCOHOL MOLECULES; BIOLOGICAL PROCESS; CELL VIABILITY; CHAPERONE SYSTEMS; COLONY FORMING UNITS; COMPLEX PATTERN; CONTROL STRAIN; DIFFERENTIAL PROTECTION; GROWTH INHIBITION; HEAT SHOCK PROTEIN; LOGP; MEMBRANE CONCENTRATION; MOLECULAR CHAPERONES; N-BUTANOL; OCTANOL-WATER PARTITION COEFFICIENT; OVER-EXPRESSION; SOLVENT TOXICITY; STRAIN TOLERANCE; TOXIC CHEMICALS; TOXIC METABOLITES; VIABLE CELLS;

ALCOHOLS; BIOFUELS; CELL GROWTH; ESCHERICHIA COLI; ETHANOL; GROWTH KINETICS; MOLECULES; STRAIN; TOXICITY;

CELL CULTURE;

1,2,4 BUTANETRIOL; 2 BUTANOL; ALCOHOL; BUTANE; BUTANOL; CHAPERONE; GROESL PROTEIN; OCTANOL; UNCLASSIFIED DRUG; WATER;

ARTICLE; BACTERIUM CULTURE; CELL COUNT; CELL GROWTH; CELL VIABILITY; COLONY FORMING UNIT; CONTROLLED STUDY; ESCHERICHIA COLI; GROWTH INHIBITION; NONHUMAN; PARTITION COEFFICIENT; PREDICTOR VARIABLE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION;

BUTANOLS; CELL SURVIVAL; DRUG TOLERANCE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; ETHANOL; HEAT-SHOCK PROTEINS; UP-REGULATION;

ESCHERICHIA COLI;

EID: 84872382030     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2012.07.009     Document Type: Article

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