메뉴 건너뛰기




Volumn 226, Issue 2, 2013, Pages 453-458

Niacin improves lipid profile but not endothelial function in patients with coronary artery disease on high dose statin therapy

Author keywords

CRP; Endothelial function; FMD; Niacin; Statin

Indexed keywords

ATORVASTATIN; C REACTIVE PROTEIN; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NICOTINIC ACID; PLACEBO; TRIACYLGLYCEROL;

EID: 84872375428     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.10.067     Document Type: Article
Times cited : (19)

References (31)
  • 1
    • 0020319988 scopus 로고
    • Stimulation of arterial endothelial cell prostacyclin synthesis by high density lipoproteins
    • Fleisher L.N., Tall A.R., Witte L.D., et al. Stimulation of arterial endothelial cell prostacyclin synthesis by high density lipoproteins. J Biol Chem 1982, 257:6653-6655.
    • (1982) J Biol Chem , vol.257 , pp. 6653-6655
    • Fleisher, L.N.1    Tall, A.R.2    Witte, L.D.3
  • 2
    • 0034927750 scopus 로고    scopus 로고
    • High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase
    • Yuhanna I.S., Zhu Y., Cox B.E., et al. High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase. Nat Med 2001, 7:853-857.
    • (2001) Nat Med , vol.7 , pp. 853-857
    • Yuhanna, I.S.1    Zhu, Y.2    Cox, B.E.3
  • 3
    • 34247339395 scopus 로고    scopus 로고
    • High-density lipoprotein cholesterol regulates endothelial progenitor cells by increasing eNOS and preventing apoptosis
    • Noor R., Shuaib U., Wang C.X., et al. High-density lipoprotein cholesterol regulates endothelial progenitor cells by increasing eNOS and preventing apoptosis. Atherosclerosis 2007, 192:92-99.
    • (2007) Atherosclerosis , vol.192 , pp. 92-99
    • Noor, R.1    Shuaib, U.2    Wang, C.X.3
  • 4
    • 33645097996 scopus 로고    scopus 로고
    • Effect of ACAT inhibition on the progression of coronary atherosclerosis
    • Nissen S.E., Tuzcu E.M., Brewer H.B., et al. Effect of ACAT inhibition on the progression of coronary atherosclerosis. N Engl J Med 2006, 354:1253-1263.
    • (2006) N Engl J Med , vol.354 , pp. 1253-1263
    • Nissen, S.E.1    Tuzcu, E.M.2    Brewer, H.B.3
  • 5
    • 36348975228 scopus 로고    scopus 로고
    • Effects of torcetrapib in patients at high risk for coronary events
    • Barter P.J., Caulfield M., Eriksson M., et al. Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med 2007, 357:2109-2122.
    • (2007) N Engl J Med , vol.357 , pp. 2109-2122
    • Barter, P.J.1    Caulfield, M.2    Eriksson, M.3
  • 6
    • 10044281651 scopus 로고    scopus 로고
    • Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins
    • Taylor A.J., Sullenberger L.E., Lee H.J., et al. Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2: a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins. Circulation 2004, 110:3512-3517.
    • (2004) Circulation , vol.110 , pp. 3512-3517
    • Taylor, A.J.1    Sullenberger, L.E.2    Lee, H.J.3
  • 7
    • 72049129430 scopus 로고    scopus 로고
    • Extended-release niacin or ezetimibe and carotid intima-media thickness
    • Taylor A.J., Villines T.C., Stanek E.J., et al. Extended-release niacin or ezetimibe and carotid intima-media thickness. N Engl J Med 2009, 361:2113-2122.
    • (2009) N Engl J Med , vol.361 , pp. 2113-2122
    • Taylor, A.J.1    Villines, T.C.2    Stanek, E.J.3
  • 8
    • 0023001772 scopus 로고
    • Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin
    • Canner P.L., Berge K.G., Wenger N.K., et al. Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin. J Am Coll Cardiol 1986, 8:1245-1255.
    • (1986) J Am Coll Cardiol , vol.8 , pp. 1245-1255
    • Canner, P.L.1    Berge, K.G.2    Wenger, N.K.3
  • 9
    • 20444470376 scopus 로고    scopus 로고
    • Relationship between carotid artery intima-media thickness and brachial artery flow-mediated dilation in middle-aged healthy men
    • Yan R.T., Anderson T.J., Charbonneau F., et al. Relationship between carotid artery intima-media thickness and brachial artery flow-mediated dilation in middle-aged healthy men. J Am Coll Cardiol 2005, 45:1980-1986.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1980-1986
    • Yan, R.T.1    Anderson, T.J.2    Charbonneau, F.3
  • 10
    • 58849127465 scopus 로고    scopus 로고
    • Evidence of endothelial dysfunction in patients with inflammatory bowel disease
    • Roifman I., Sun Y.C., Fedwick J.P., et al. Evidence of endothelial dysfunction in patients with inflammatory bowel disease. Clin Gastroenterol Hepatol 2009, 7:175-182.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 175-182
    • Roifman, I.1    Sun, Y.C.2    Fedwick, J.P.3
  • 11
    • 65649100805 scopus 로고    scopus 로고
    • Comparison of new measures of vascular function to flow mediated dilatation as a measure of cardiovascular risk factors
    • Philpott A.C., Lonn E., Title L.M., et al. Comparison of new measures of vascular function to flow mediated dilatation as a measure of cardiovascular risk factors. Am J Cardiol 2009, 103:1610-1615.
    • (2009) Am J Cardiol , vol.103 , pp. 1610-1615
    • Philpott, A.C.1    Lonn, E.2    Title, L.M.3
  • 12
    • 33644875186 scopus 로고    scopus 로고
    • Cross-sectional relations of peripheral microvascular function, cardiovascular disease risk factors, and aortic stiffness: the Framingham Heart Study
    • Mitchell G.F., Vita J.A., Larson M.G., et al. Cross-sectional relations of peripheral microvascular function, cardiovascular disease risk factors, and aortic stiffness: the Framingham Heart Study. Circulation 2005, 112:3722-3728.
    • (2005) Circulation , vol.112 , pp. 3722-3728
    • Mitchell, G.F.1    Vita, J.A.2    Larson, M.G.3
  • 13
    • 67349209273 scopus 로고    scopus 로고
    • Effects of oral niacin on endothelial dysfunction in patients with coronary artery disease: results of the randomized, double-blind, placebo-controlled INEF study
    • Warnholtz A., Wild P., Ostad M.A., et al. Effects of oral niacin on endothelial dysfunction in patients with coronary artery disease: results of the randomized, double-blind, placebo-controlled INEF study. Atherosclerosis 2009, 204:216-221.
    • (2009) Atherosclerosis , vol.204 , pp. 216-221
    • Warnholtz, A.1    Wild, P.2    Ostad, M.A.3
  • 14
    • 0028784709 scopus 로고
    • Close relation of endothelial function in the human coronary and peripheral circulations
    • Anderson T.J., Uehata A., Gerhard M.D., et al. Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol 1995, 26:1235-1241.
    • (1995) J Am Coll Cardiol , vol.26 , pp. 1235-1241
    • Anderson, T.J.1    Uehata, A.2    Gerhard, M.D.3
  • 15
    • 34248196019 scopus 로고    scopus 로고
    • Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: the Cardiovascular Health Study
    • Yeboah J., Crouse J.R., Hsu F.C., et al. Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: the Cardiovascular Health Study. Circulation 2007, 115:2390-2397.
    • (2007) Circulation , vol.115 , pp. 2390-2397
    • Yeboah, J.1    Crouse, J.R.2    Hsu, F.C.3
  • 16
    • 69449105430 scopus 로고    scopus 로고
    • Predictive value of brachial flow-mediated dilation for incident cardiovascular events in a population-based study: the multi-ethnic study of atherosclerosis
    • Yeboah J., Folsom A.R., Burke G.L., et al. Predictive value of brachial flow-mediated dilation for incident cardiovascular events in a population-based study: the multi-ethnic study of atherosclerosis. Circulation 2009, 120:502-509.
    • (2009) Circulation , vol.120 , pp. 502-509
    • Yeboah, J.1    Folsom, A.R.2    Burke, G.L.3
  • 17
    • 78751620578 scopus 로고    scopus 로고
    • Microvascular function predicts cardiovascular events in primary prevention: long-term results from the Firefighters and Their Endothelium (FATE) study
    • Anderson T.J., Charbonneau F., Title L.M., et al. Microvascular function predicts cardiovascular events in primary prevention: long-term results from the Firefighters and Their Endothelium (FATE) study. Circulation 2011, 123:163-169.
    • (2011) Circulation , vol.123 , pp. 163-169
    • Anderson, T.J.1    Charbonneau, F.2    Title, L.M.3
  • 18
    • 0028939363 scopus 로고
    • The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion
    • Anderson T.J., Meredith I.T., Yeung A.C., et al. The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion. N Engl J Med 1995, 332:488-493.
    • (1995) N Engl J Med , vol.332 , pp. 488-493
    • Anderson, T.J.1    Meredith, I.T.2    Yeung, A.C.3
  • 19
    • 0033966627 scopus 로고    scopus 로고
    • Comparative study of ACE-inhibition, angiotensin II antagonism, and calcium channel blockade on flow-mediated vasodilation in patients with coronary disease (BANFF study)
    • Anderson T.J., Elstein E., Haber H., et al. Comparative study of ACE-inhibition, angiotensin II antagonism, and calcium channel blockade on flow-mediated vasodilation in patients with coronary disease (BANFF study). J Am Coll Cardiol 2000, 35:60-66.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 60-66
    • Anderson, T.J.1    Elstein, E.2    Haber, H.3
  • 20
    • 84855171302 scopus 로고    scopus 로고
    • Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy
    • Boden W.E., Probstfield J.L., Anderson T., et al. Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. N Engl J Med 2011, 365:2255-2267.
    • (2011) N Engl J Med , vol.365 , pp. 2255-2267
    • Boden, W.E.1    Probstfield, J.L.2    Anderson, T.3
  • 21
    • 70350516769 scopus 로고    scopus 로고
    • Effects of high-dose modified-release nicotinic acid on atherosclerosis and vascular function: a randomized, placebo-controlled, magnetic resonance imaging study
    • Lee J.M., Robson M.D., Yu L.M., et al. Effects of high-dose modified-release nicotinic acid on atherosclerosis and vascular function: a randomized, placebo-controlled, magnetic resonance imaging study. J Am Coll Cardiol 2009, 54:1787-1794.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 1787-1794
    • Lee, J.M.1    Robson, M.D.2    Yu, L.M.3
  • 22
    • 0036301760 scopus 로고    scopus 로고
    • A novel mechanism for the beneficial vascular effects of high-density lipoprotein cholesterol: enhanced vasorelaxation and increased endothelial nitric oxide synthase expression
    • Kuvin J.T., Ramet M.E., Patel A.R., et al. A novel mechanism for the beneficial vascular effects of high-density lipoprotein cholesterol: enhanced vasorelaxation and increased endothelial nitric oxide synthase expression. Am Heart J 2002, 144:165-172.
    • (2002) Am Heart J , vol.144 , pp. 165-172
    • Kuvin, J.T.1    Ramet, M.E.2    Patel, A.R.3
  • 23
    • 33744517651 scopus 로고    scopus 로고
    • Accumulation of chylomicron remnants and impaired vascular reactivity occur in subjects with isolated low HDL cholesterol: effects of niacin treatment
    • Benjo A.M., Maranhao R.C., Coimbra S.R., et al. Accumulation of chylomicron remnants and impaired vascular reactivity occur in subjects with isolated low HDL cholesterol: effects of niacin treatment. Atherosclerosis 2006, 187:116-122.
    • (2006) Atherosclerosis , vol.187 , pp. 116-122
    • Benjo, A.M.1    Maranhao, R.C.2    Coimbra, S.R.3
  • 24
    • 74549172922 scopus 로고    scopus 로고
    • Endothelial-vasoprotective effects of high-density lipoprotein are impaired in patients with type 2 diabetes mellitus but are improved after extended-release niacin therapy
    • Sorrentino S.A., Besler C., Rohrer L., et al. Endothelial-vasoprotective effects of high-density lipoprotein are impaired in patients with type 2 diabetes mellitus but are improved after extended-release niacin therapy. Circulation 2010, 121:110-122.
    • (2010) Circulation , vol.121 , pp. 110-122
    • Sorrentino, S.A.1    Besler, C.2    Rohrer, L.3
  • 25
    • 34447324649 scopus 로고    scopus 로고
    • Extended-release niacin raises adiponectin and leptin
    • Westphal S., Borucki K., Taneva E., et al. Extended-release niacin raises adiponectin and leptin. Atherosclerosis 2007, 193:361-365.
    • (2007) Atherosclerosis , vol.193 , pp. 361-365
    • Westphal, S.1    Borucki, K.2    Taneva, E.3
  • 26
    • 0037352280 scopus 로고    scopus 로고
    • PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect
    • Tunaru S., Kero J., Schaub A., et al. PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect. Nat Med 2003, 9:352-355.
    • (2003) Nat Med , vol.9 , pp. 352-355
    • Tunaru, S.1    Kero, J.2    Schaub, A.3
  • 28
    • 0031595186 scopus 로고    scopus 로고
    • HDL3-mediated inhibition of thrombin-induced platelet aggregation and fibrinogen binding occurs via decreased production of phosphoinositide-derived second messengers 1,2-diacylglycerol and inositol 1,4,5-tris-phosphate
    • Nofer J.R., Walter M., Kehrel B., et al. HDL3-mediated inhibition of thrombin-induced platelet aggregation and fibrinogen binding occurs via decreased production of phosphoinositide-derived second messengers 1,2-diacylglycerol and inositol 1,4,5-tris-phosphate. Arterioscler Thromb Vasc Biol 1998, 18:861-869.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 861-869
    • Nofer, J.R.1    Walter, M.2    Kehrel, B.3
  • 29
    • 77957871747 scopus 로고    scopus 로고
    • Activation of intracellular signaling systems by high-density lipoproteins
    • Toth P.P. Activation of intracellular signaling systems by high-density lipoproteins. J Clin Lipidol 2010, 4:376-381.
    • (2010) J Clin Lipidol , vol.4 , pp. 376-381
    • Toth, P.P.1
  • 30
    • 67349105071 scopus 로고    scopus 로고
    • Flow-mediated dilation in patients with coronary artery disease is enhanced by high dose atorvastatin compared to combined low dose atorvastatin and ezetimibe: results of the CEZAR study
    • Ostad M.A., Eggeling S., Tschentscher P., et al. Flow-mediated dilation in patients with coronary artery disease is enhanced by high dose atorvastatin compared to combined low dose atorvastatin and ezetimibe: results of the CEZAR study. Atherosclerosis 2009, 205:227-232.
    • (2009) Atherosclerosis , vol.205 , pp. 227-232
    • Ostad, M.A.1    Eggeling, S.2    Tschentscher, P.3
  • 31
    • 42149136762 scopus 로고    scopus 로고
    • Effects of niacin on glucose control in patients with dyslipidemia
    • Goldberg R.B., Jacobson T.A. Effects of niacin on glucose control in patients with dyslipidemia. Mayo Clin Proc 2008, 83:470-478.
    • (2008) Mayo Clin Proc , vol.83 , pp. 470-478
    • Goldberg, R.B.1    Jacobson, T.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.