Clinical pharmacology of analgesics assessed with human experimental pain models: Bridging basic and clinical research

British Journal of Pharmacology

Volumn 168, Issue 3, 2013, Pages 534-553

  Oertel, Bruno Georg ^a,b   Lötsch, Jörn ^b  

^a FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

analgesics; drug development; experimental human pain models; pain; translational pharmacology

Indexed keywords

ACETYLSALICYLIC ACID; ALFENTANIL; ANALGESIC AGENT; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE; CANNABIS DERIVATIVE; CAPSAICIN; CLONAZEPAM; CLONIDINE; CODEINE; CYCLOOXYGENASE 2 INHIBITOR; DIAZEPAM; DICLOFENAC; DIPYRIDAMOLE; FENTANYL; FLUPIRTINE; GABAPENTIN; IBUPROFEN; INDOMETACIN; LAMOTRIGINE; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE DERIVATIVE; POTASSIUM CHANNEL BLOCKING AGENT; PREGABALIN; TRAMADOL; UNINDEXED DRUG; VANILLOID RECEPTOR 1 ANTAGONIST;

ABDOMINAL PAIN; ANALGESIA; CANCER PAIN; CHEMOSENSITIZATION; CHRONIC PAIN; DISEASE CLASSIFICATION; DISEASE MODEL; DRUG EFFICACY; DRUG MECHANISM; DRUG RESEARCH; DRUG TARGETING; DRUG TREATMENT FAILURE; FACE PAIN; GASTROINTESTINAL PAIN; HUMAN; HYPERALGESIA; INFLAMMATION; KIDNEY COLIC; MIGRAINE; MUSCULOSKELETAL PAIN; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; OSTEOARTHRITIS; OUTCOME ASSESSMENT; PAIN; PHANTOM PAIN; POSTHERPETIC NEURALGIA; POSTOPERATIVE PAIN; PREDICTION; PRIORITY JOURNAL; REVIEW; TENSION HEADACHE; TREATMENT RESPONSE;

ANALGESIA; ANALGESICS; ANIMALS; BIOMEDICAL RESEARCH; HUMANS; MODELS, BIOLOGICAL; PAIN;

EID: 84872374764     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12023     Document Type: Review

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