Localization of cholesterol, amyloid and glia in Alzheimer's disease transgenic mouse brain tissue using time-of-flight secondary ion mass spectrometry (ToF-SIMS) and immunofluorescence imaging

Acta Neuropathologica

Volumn 125, Issue 1, 2013, Pages 145-157

  Solé Domènech, Santiago ^a   Sjövall, Peter ^b   Vukojević, Vladana ^a   Fernando, Ruani ^c   Codita, Alina ^a   Salve, Sachin ^a   Bogdanović, Nenad ^a   Mohammed, Abdul H ^a   Hammarström, Per ^d   Nilsson, K Peter R ^d   Laferla, Frank M ^e   Jacob, Stefan ^a   Berggren, Per Olof ^a   Giménez Llort, Lydia ^f   Schalling, Martin ^a   Terenius, Lars ^a   Johansson, Björn ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b SP TECHNICAL RESEARCH INSTITUTE OF SWEDEN   (Sweden)

^c HÔPITAL SAINT ELOI   (France)

^d LINKÖPING UNIVERSITY   (Sweden)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Alzheimer's disease; Amyloid beta; Brain; Cholesterol; Glia; Imaging; ToF SIMS

Indexed keywords

AMYLOID BETA PROTEIN; CELL PROTEIN; CHOLESTEROL; GLIAL FIBRILLARY ACIDIC PROTEIN; PROTEIN IBA1; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; GLIA CELL; HIPPOCAMPUS; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LIPID ANALYSIS; LIPID STORAGE; MOLECULAR IMAGING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SCANNING ELECTRON MICROSCOPY; TIME OF FLIGHT MASS SPECTROMETRY; TIME OF FLIGHT SECONDARY ION MASS SPECTROMETRY;

ALZHEIMER DISEASE; AMYLOID; ANIMALS; BRAIN; CHOLESTEROL; DISEASE MODELS, ANIMAL; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, TRANSGENIC; NEUROGLIA; NEURONS; SPECTROMETRY, MASS, SECONDARY ION;

EID: 84872363429     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-012-1046-9     Document Type: Article

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