HP-β-CD-PLGA nanoparticles improve the penetration and bioavailability of puerarin and enhance the therapeutic effects on brain ischemia-reperfusion injury in rats

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 386, Issue 1, 2013, Pages 61-70

  Tao, Hai Quan ^a   Meng, Qingfeng ^b   Li, Ming Hui ^c   Yu, Hui ^c   Liu, Mei Fang ^c   Du, Dan ^c   Sun, Shou Li ^c   Yang, Hai Cheng ^a   Wang, Yan Ming ^c   Ye, Wei ^a   Yang, Li Zhuang ^a   Zhu, Da Ling ^c   Jiang, Chuan Lu ^a   Peng, Hai Sheng ^c  

^a THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^c HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Brain ischemic; Computerized tomography scan; Electroencephalogram; HP CD inclusion complex; PLGA nanoparticles; Puerarin

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; GELATIN; NANOPARTICLE; PHOSPHATE BUFFERED SALINE; POLYGLACTIN; PUERARIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BRAIN LEVEL; DRUG DEGRADATION; DRUG EFFICACY; DRUG PENETRATION; DRUG RELEASE; DRUG SOLUBILITY; ELECTROENCEPHALOGRAM; ELECTRON MICROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; RAT; REPERFUSION INJURY; VISCOSITY;

ANIMALS; BETA-CYCLODEXTRINS; BIOLOGICAL AVAILABILITY; BLOOD-BRAIN BARRIER; BRAIN ISCHEMIA; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CARRIERS; GELATIN; ISOFLAVONES; LACTIC ACID; MALE; NANOPARTICLES; POLYGLYCOLIC ACID; RATS; RATS, WISTAR; REPERFUSION INJURY; SOLUBILITY; TIME FACTORS; TISSUE DISTRIBUTION; TOMOGRAPHY, X-RAY COMPUTED; VASODILATOR AGENTS; VISCOSITY;

EID: 84872359343     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-012-0804-5     Document Type: Article

References (26)

1. Agueros M, Ruiz-Gaton L, Vauthier C, Bouchemal K, Espuelas S, Ponchel G, Irache JM (2009) Combined hydroxypropyl-beta-cyclodextrin and poly(anhydride) nanoparticles improve the oral permeability of paclitaxel. Eur J Pharm Sci 38:405-413
2. Chang Y, Hsieh CY, Peng ZA, Yen TL, Hsiao G, Chou DS, Chen CM, Sheu JR (2009) Neuroprotective mechanisms of puerarin in middle cerebral artery occlusion-induced brain infarction in rats. J Biomed Sci 16:9
3. Chauhan R, Madan J, Kaushik D, Sardana S, Pandey RS, Sharma R (2011) Inclusion complex of colchicine in hydroxypropyl-beta-cyclodextrin tenders better solubility and improved pharmacokinetics. Pharm Dev Technol. doi: 10.3109/10837450.2011.591801
4. Choo MK, Park EK, Yoon HK, Kim DH (2002) Antithrombotic and antiallergic activities of daidzein, a metabolite of puerarin and daidzin produced by human intestinal microflora. Biol Pharm Bull 25:1328-1332
5. Chung TW, Huang YY, Tsai YL, Liu YZ (2002) Effects of solvent evaporation rate on the properties of protein-loaded PLLA and PDLLA microspheres fabricated by emulsion-solvent evaporation process. J Microencapsul 19:463-471
6. Gavini E, Spada G, Rassu G, Cerri G, Brundu A, Cossu M, Sorrenti M, Giunchedi P (2011) Development of solid nanoparticles based on hydroxypropyl-beta-cyclodextrin aimed for the colonic transmucosal delivery of diclofenac sodium. J Pharm Pharmacol 63:472-482
7. Giffard RG, Swanson RA (2005) Ischemia-induced programmed cell death in astrocytes. Glia 50:299-306
8. Gil ES, Li J, Xiao H, Lowe TL (2009) Quaternary ammonium beta-cyclodextrin nanoparticles for enhancing doxorubicin permeability across the in vitro blood-brain barrier. Biomacromolecules 10:505-516
9. Gu FG, Cui FD, Gao YL (2005) Preparation of prostaglandin E1-hydroxypropyl-beta-cyclodextrin complex and its nasal delivery in rats. Int J Pharm 290:101-108
10. Han RM, Chen CH, Tian YX, Zhang JP, Skibsted LH (2010) Fast regeneration of carotenoids from radical cations by isoflavonoid dianions: importance of the carotenoid keto group for electron transfer. J Phys Chem 114:126-132
11. Jug M, Becirevic-Lacan M (2007) Screening of mucoadhesive microparticles containing hydroxypropyl-beta-cyclodextrin for the nasal delivery of risperidone. Combinatorial chemistry & high throughput screening 10:358-367
12. Li Q, Zhang R, Ge YL, Mei YW, Guo YL (2009) Effects of neuregulin on expression of MMP-9 and NSE in brain of ischemia/reperfusion rat. J Mol Neurosci 38:207-215
13. Lin RC, Guthrie S, Xie CY, Mai K, Lee DY, Lumeng L, Li TK (1996) Isoflavonoid compounds extracted from Pueraria lobata suppress alcohol preference in a pharmacogenetic rat model of alcoholism. Alcohol Clin Exp Res 20:659-663
14. Peng HS, Liu XJ, Lv GX, Sun B, Kong QF, Zhai DX, Wang Q, Zhao W, Wang GY, Wang DD, Li HL, Jin LH, Kostulas N (2008) Voriconazole into PLGA nanoparticles: improving agglomeration and antifungal efficacy. Int J Pharm 352:29-35
15. Ren K, Zhang Z, Li Y, Liu J, Zhao D, Zhao Y, Gong T (2009) Physicochemical characteristics and oral bioavailability of andrographolide complexed with hydroxypropyl-beta-cyclodextrin. Die Pharmazie 64:515-520
16. Sachdeva A, Cai S (2009) Structural differences of proteins between solution state and solid state probed by attenuated total reflection Fourier transform infrared spectroscopy. Appl Spectrosc 63:458-464
17. Sato T, Mizuno K, Ishii F (2010) A novel administration route of edaravone - II: mucosal absorption of edaravone from edaravone/hydroxypropyl- beta-cyclodextrin complex solution including l-cysteine and sodium hydrogen sulfite. Pharmacology 85:88-94
18. Sharp FR, Liu J, Bernabeu R (2002) Neurogenesis following brain ischemia. Brain Res Dev Brain Res 134:23-30
19. Tilloy S, Monnaert V, Fenart L, Bricout H, Cecchelli R, Monflier E (2006) Methylated beta-cyclodextrin as P-gp modulators for deliverance of doxorubicin across an in vitro model of blood-brain barrier. Bioorg Med Chem Lett 16:2154-2157
20. Tortella FC, Rose J, Robles L, Moreton JE, Hughes J, Hunter JC (1997) EEG spectral analysis of the neuroprotective kappa opioids enadoline and PD117302. J Pharmacol Exp Ther 282:286-293
21. Wu H, Lu C, Zhou A, Min Z, Zhang Y (2009) Enhanced oral bioavailability of puerarin using microemulsion vehicle. Drug Dev and Ind Pharm 35:138-144
22. Xu X, Zhang S, Zhang L, Yan W, Zheng X (2005) The neuroprotection of puerarin against cerebral ischemia is associated with the prevention of apoptosis in rats. Planta Med 71:585-591
23. Yan LP, Zhuang YL, Chan SW, Chen SL, Shi GG (2009) Analysis of the mechanisms underlying the endothelium-dependent antivasoconstriction of puerarin in rat aorta. Naunyn Schmiedebergs Arch Pharmacol 379:587-597
24. Yang CY, Tsay SY, Tsiang RC (2000) An enhanced process for encapsulating aspirin in ethyl cellulose microcapsules by solvent evaporation in an O/W emulsion. J Microencapsul 17:269-277
25. Yue PF, Hai-Long Yuan HL, Zhu WF, Cong LB, Xie H, Liu ZG, Wang LJ, Xiao XH (2008) The study to reduce the hemolysis side effect of puerarin by a submicron emulsion delivery system. Biol Pharm Bull 31:45-50
26. + current in rat ventricular. Acta Pharmacol Sin 24:1212-1216