Inclusion complex of colchicine in hydroxypropyl-β-cyclodextrin tenders better solubility and improved pharmacokinetics

Pharmaceutical Development and Technology

Volumn 18, Issue 2, 2013, Pages 313-322

  Chauhan, Ritu ^a   Madan, Jitender ^a   Kaushik, Dinesh ^a   Sardana, Satish ^a   Pandey, Ravi Shankar ^b   Sharma, Rakesh ^c  

^a Hindu College   (India)

^b GURU GHASIDAS UNIVERSITY   (India)

^c UNIVERSITY OF DELHI   (India)

Author keywords

Bioavailability; Colchicine; HP CD; Inclusion complex; Pharmacokinetics

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; COLCHICINE;

ANIMAL EXPERIMENT; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG METABOLISM; DRUG SOLUBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROSCOPY; MALE; MOUSE; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SCANNING ELECTRON MICROSCOPY; X RAY DIFFRACTION;

ANIMALS; BETA-CYCLODEXTRINS; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; COLCHICINE; FEMALE; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; PROTONS; RANDOM ALLOCATION; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; X-RAY DIFFRACTION;

EID: 84872478515     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450.2011.591801     Document Type: Article

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