Protein expression profiling in interstitial cystitis/painful bladder syndrome: A pilot study of proteins associated with inflammation, apoptosis, and angiogenesis

Urological Science

Volumn 23, Issue 4, 2012, Pages 107-113

  Shie, Jia Heng ^a,b   Liu, Hsin Tzu ^a,b   Kuo, Hann Chorng ^a,b  

^a BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^b TZU CHI UNIVERSITY   (Taiwan)

Author keywords

Angiogenesis; Apoptosis; Inflammation; Interstitial cystitis; Painful bladder syndrome

Indexed keywords

ACTIVIN A; ADAMTS1 PROTEIN; ANGIOGENIN; ANGIOPOIETIN 1; BOTULINUM TOXIN A; CXCL16 CHEMOKINE; CYTOKINE; ENDOGLIN; ENDOSTATIN; FIBROBLAST GROWTH FACTOR 4; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; KERATINOCYTE GROWTH FACTOR; LEPTIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PENTRAXIN 3; PERSEPHIN; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR AB; PROLACTIN; SERINE PROTEINASE INHIBITOR; THROMBOCYTE FACTOR 4; THROMBOSPONDIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 4; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN; VASCULOTROPIN C;

ANGIOGENESIS; APOPTOSIS; ARTICLE; BLADDER BIOPSY; BLADDER DISEASE; CHRONIC INFLAMMATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; INFLAMMATION; INTERSTITIAL CYSTITIS; PILOT STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MICROARRAY; PROTEOMICS; SIGNAL TRANSDUCTION; URINALYSIS;

EID: 84872325792     PISSN: 18795226     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.urols.2012.10.003     Document Type: Article

References (38)

1. Keay S. Cell signaling in interstitial cystitis/painful bladder syndrome. Cell Signal 2008, 20:2174-2179.
2. Homma Y., Ueda T., Tomoe H., Tomoe H., Lin A.T., Kuo H.C., et al. Clinical guidelines for interstitial cystitis and hypersensitive bladder syndrome. Int J Urol 2009, 16:597-615.
3. Sant G.R., Kempuraj D., Marchand J.E., Theoharides T.C. The mast cell in interstitial cystitis: role in pathophysiology and pathogenesis. Urology 2007, 69:34-40.
4. Erickson D.R., Belchis D.A., Dabbs D.J. Inflammatory cell types and clinical features of interstitial cystitis. J Urol 1997, 158:790-793.
5. Shie J.H., Kuo H.C. Higher levels of cell apoptosis and abnormal E-cadherin expression in the urothelium are associated with inflammation in patients with interstitial cystitis/painful bladder syndrome. BJU Int 2011, 108:E136-E141.
6. Weber C., Fraemohs L., Dejana E. The role of junctional adhesion molecules in vascular inflammation. Nat Rev Immunol 2007, 7:467-477.
7. Nazif O., Teichman J.M., Gebhart G.F. Neural upregulation in interstitial cystitis. Urology 2007, 69(Suppl):24-33.
8. Bouchelouche K., Nordling J. Recent developments in the management of interstitial cystitis. Curr Opin Urol 2003, 13:309-313.
9. Liu H.T., Tyagi P., Chancellor M.B., Kuo H.C. Urinary nerve growth factor level is increased in patients with interstitial cystitis/bladder pain syndrome and decreased in responders to treatment. BJU Int 2009, 104:1476-1481.
10. Liu H.T., Tyagi P., Chancellor M.B., Kuo H.C. Urinary nerve growth factor but not prostaglandin E2 increases in patients with interstitial cystitis/bladder pain syndrome and detrusor overactivity. BJU Int 2010, 106:1681-1685.
11. Chung S.D., Liu H.T., Lin H., Kuo H.C. Elevation of serum c-reactive protein in patients with OAB and IC/BPS implies chronic inflammation in the urinary bladder. Neurourol Urodyn 2011, 30:417-420.
12. Shie J.H., Liu H.T., Kuo H.C. Increased cell apoptosis of the urothelium is closely linked to chronic inflammation in interstitial cystitis/painful bladder syndrome. Urology 2012, 79:484. e7-13.
13. Rossberger J., Fall M., Gustafsson C.K., Peeker R. Does mast cell density predict the outcome after transurethral resection of Hunner's ulcer lesions in patients with type 3C bladder pain syndrome/interstitial cystitis?. Scand J Urol Nephrol 2010, 44:433-437.
14. Erickson D.R., Tomzazewski J.E., Kunselman A.R., Stetter C.M., Peters K.M., Rovner E.S., et al. Urine maerkers do not predict biopsy findings or presence of bladder ulcers in interstitial cystitis/painful bladder syndrome. J Urol 2008, 179:1850-1856.
15. Kaczmarek E., Gorna A., Majewski P. Techniques of image analysis for quantitative immunohistochemistry. Rocz Akad Med Bialymst 2004, 49(Suppl. 1):155-158.
16. Liebert M., Wedemeyer G., Stein J.A., Washington R., Faerber G., Flint A., et al. Evidence for urothelial cell activation in interstitial cystitis. J Urol 1993, 149:470-475.
17. Christmas T.J., Bottazzo G.F. Abnormal urothelial HLA-DR expression in interstitial cystitis. Clin Exp Immunol 1992, 87:450-454.
18. Keay S., Kleinberg M., Zhang C.O., Hise M.K., Warren J.W. Bladder epithelial cells from patients with interstitial cystitis produce an inhibitor of heparin-binding epidermal growth factor-like growth factor production. J Urol 2000, 164:2112-2118.
19. Zhang C.O., Wang J.Y., Koch K.R., Keay S. Regulation of tight junction proteins and bladder epithelial paracellular permeability by an antiproliferative factor from patients with interstitial cystitis. J Urol 2005, 174:2382-2387.
20. Keay S., Seillier-Moiseiwitsch F., Zhang C.O., Chai T.C., Zhang J. Changes in human bladder epithelial cell gene expression associated with interstitial cystitis or antiproliferative factor treatment. Physiol Genomics 2003, 14:107-115.
21. Keay S., Zhang C.O., Kagen D.I., Hise M.K., Jacobs S.C., Hebel J.R., et al. Concentrations of specific epithelial growth factors in the urine of interstitial cystitis patients and controls. J Urol 1997, 158:1983-1988.
22. Erickson D.R., Xie S.X., Bhavanandan V.P., Wheeler M.A., Hurst R.E., Demers L.M., et al. A comparison of multiple urine markers for interstitial cystitis. J Urol 2002, 167:2461-2469.
23. Ueda T., Tamaki M., Ogawa O., Yoshimura N. Over expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in patients with interstitial cystitis and bladder carcinoma. J Urol 2002, 167:347-351.
24. Parsons C.L., Stein P., Zupkas P., Chenoweth M., Argade S.P., Proctor J.G., et al. Defective Tamm-Horsfall protein in patients with interstitial cystitis. J Urol 2007, 178:2665-2670.
25. Frank P.G., Lisanti M.P. ICAM-1: role in inflammation and in the regulation of vascular permeability. Am J Physiol Heart Circ Physiol 2008, 295:H926-H927.
26. Cai G., Zhang X., Hong Q., Shao F., Shang X., Fu B., et al. Tissue inhibitor of metalloproteinase-1 exacerbated renal interstitial fibrosis through enhancing inflammation. Nephrol Dial Transplant 2008, 23:1861-1875.
27. Lal B.K., Varma S., Pappas P.J., Hobson R.W., Duran W.N. VEGF increases permeability of the endothelial cell monolayer by activation of PKB/akt, endothelial nitric-oxide synthase, and MAP kinase pathways. Microvasc Res 2001, 62:252-262.
28. Bannerman D.D., Sathyamoorthy M., Goldblum S.E. Bacterial lipopolysaccharide disrupts endothelial monolayer integrity and survival signaling events through caspase cleavage of adherens junction proteins. J Biol Chem 1998, 273:35371-35380.
29. Dudek S.M., Garcia J.G. Cytoskeletal regulation of pulmonary vascular permeability. J Appl Physiol 2001, 91:1487-1500.
30. Krizbai I.A., Deli M.A. Signalling pathways regulating the tight junction permeability in the blood-brain barrier. Cell Mol Biol (Noisy-le-grand) 2003, 49:23-31.
31. Cook D.N. The role of MIP-1 alpha in inflammation and hematopoiesis. J Leukoc Biol 1996, 59:61-66.
32. Ambrosino C., Nebreda A.R. Cell cycle regulation by p38 MAP kinases. Biol Cell 2001, 93:47-51.
33. Jiang P., Du W., Wu M. p53 and Bad: remote strangers become close friends. Cell Res 2007, 17:283-285.
34. Rath P.C., Aggarwal B.B. TNF-induced signaling in apoptosis. J Clin Immunol 1999, 19:350-364.
35. Idriss H.T., Naismith J.H. TNF alpha and the TNF receptor superfamily: structure-function relationship(s). Microsc Res Tech 2000, 50:184-195.
36. Herzberg U., Eliav E., Dorsey J.M., Gracely R.H., Kopin I.J. NGF involvement in pain induced by chronic constriction injury of the rat sciatic nerve. Neuroreport 1997, 8:1613-1618.
37. Schafers M., Geis C., Brors D., Yaksh T.L., Sommer C. Anterograde transport of tumor necrosis factor-alpha in the intact and injured rat sciatic nerve. J Neurosci 2002, 22:536-545.
38. Gaur U., Aggarwal B.B. Regulation of proliferation, survival and apoptosis by members of the TNF superfamily. Biochem Pharmacol 2003, 66:1403-1408.