Alpha-heteroatom derivatized analogues of 3-(acetylhydroxyamino)propyl phosphonic acid (FR900098) as antimalarials

Journal of Medicinal Chemistry

Volumn 56, Issue 1, 2013, Pages 376-380

  Verbrugghen, Thomas ^a   Vandurm, Pierre ^b   Pouyez, Jenny ^b   Maes, Louis ^c   Wouters, Johan ^b   Van Calenbergh, Serge ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY OF NAMUR   (Belgium)

^c UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

3 (ACETYLHYDROXYAMINO)PROPYL PHOSPHONIC ACID; 3 (N ACETYL N HYDROXYAMINO)PROPYLPHOSPHONIC ACID; AMIDE; ANTIMALARIAL AGENT; CARBON; ETHER; FOSMIDOMYCIN; HYDROXYL GROUP; NITROGEN; OXYGEN; PHOSPHONIC ACID DERIVATIVE; TRIAZOLE; UNCLASSIFIED DRUG; UREA;

ARTICLE; DERIVATIZATION; DRUG INHIBITION; DRUG POTENCY; DRUG STRUCTURE; ENZYME INHIBITION; ERYTHROCYTE; IC 50; PLASMODIUM FALCIPARUM; RACEMIC MIXTURE; SUBSTITUTION REACTION;

ALDOSE-KETOSE ISOMERASES; ANTIMALARIALS; ERYTHROCYTES; FOSFOMYCIN; HUMANS; MOLECULAR DOCKING SIMULATION; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84872315079     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm301577q     Document Type: Article

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