-
1
-
-
34547176642
-
Unravelling the pathogenesis of inflammatory bowel disease
-
Xavier RJ, Podolsky DK. Unravelling the pathogenesis of inflammatory bowel disease. Nature 2007;448:427-34.
-
(2007)
Nature
, vol.448
, pp. 427-434
-
-
Xavier, R.J.1
Podolsky, D.K.2
-
3
-
-
33947301294
-
Immune dysfunction in inflammatory bower disease
-
Neuman MG Immune dysfunction in inflammatory bower disease. Transl Res 2007;149:173-86.
-
(2007)
Transl Res
, vol.149
, pp. 173-186
-
-
Neuman, M.G.1
-
4
-
-
35148833220
-
Tissue levels of tumor necrosis factor-alpha correlates with grade of inflammation in untreated ulcerative colitis
-
Olsen T, Goll R, Cui G, Husebekk A, Vonen B, Birketvedt GS, et al. Tissue levels of tumor necrosis factor-alpha correlates with grade of inflammation in untreated ulcerative colitis. Scand J Gastroenterol 2007;42:1312-20.
-
(2007)
Scand J Gastroenterol
, vol.42
, pp. 1312-1320
-
-
Olsen, T.1
Goll, R.2
Cui, G.3
Husebekk, A.4
Vonen, B.5
Birketvedt, G.S.6
-
5
-
-
0037299902
-
Upregulation of interleukin-12 and -17 in active inflammatory bowel disease
-
Nielsen OH, Kirman I, Rudiger N, Hendel J, Vainer B. Upregulation of interleukin-12 and -17 in active inflammatory bowel disease. Scand J Gastroenterol 2003;38:180-5.
-
(2003)
Scand J Gastroenterol
, vol.38
, pp. 180-5
-
-
Nielsen, O.H.1
Kirman, I.2
Rudiger, N.3
Hendel, J.4
Vainer, B.5
-
6
-
-
80655122800
-
TH1 and TH17 interactions in untreated inflamed mucosa of inflammatory bowel disease, and their potential to mediate the inflammation
-
Olsen T, Rismo R, Cui G, Goll R, Christiansen I, Florholmen J. TH1 and TH17 interactions in untreated inflamed mucosa of inflammatory bowel disease, and their potential to mediate the inflammation. Cytokine 2011;56:633-40.
-
(2011)
Cytokine
, vol.56
, pp. 633-640
-
-
Olsen, T.1
Rismo, R.2
Cui, G.3
Goll, R.4
Christiansen, I.5
Florholmen, J.6
-
7
-
-
68949144958
-
High levels of proinflammatory cytokines, but not of markers of tissue injury, in unaffected intestinal areas from patients with IBD
-
Leon AJ, Gomez E, Garrote JA, Bernardo D, Barrera A, Marcos JL, et al. High levels of proinflammatory cytokines, but not of markers of tissue injury, in unaffected intestinal areas from patients with IBD. Mediators Inflamm 2009;2009:1-10.
-
(2009)
Mediators Inflamm
, vol.2009
, pp. 1-10
-
-
Leon, A.J.1
Gomez, E.2
Garrote, J.A.3
Bernardo, D.4
Barrera, A.5
Marcos, J.L.6
-
10
-
-
33644666978
-
Leukocytapheresis therapy for steroid-naïve patients with active ulcerative colitis: Its clinical efficacy and adverse effects compared with those of conventional steroid therapy
-
Nishioka C, Aoyama N, Maekawa S, Shirasaka D, Nakahara T, Tamura T, et al. Leukocytapheresis therapy for steroid-naïve patients with active ulcerative colitis: its clinical efficacy and adverse effects compared with those of conventional steroid therapy. J Gastroenterol Hepatol 2005;20:1567-71.
-
(2005)
J Gastroenterol Hepatol
, vol.20
, pp. 1567-1571
-
-
Nishioka, C.1
Aoyama, N.2
Maekawa, S.3
Shirasaka, D.4
Nakahara, T.5
Tamura, T.6
-
11
-
-
48449086177
-
Long-term effect of tacrolimus therapy in patients with refractory ulcerative colitis
-
Yamamoto S, Nakase H, Mikami S, Inoue S, Yoshino T, Takeda Y, et al. Long-term effect of tacrolimus therapy in patients with refractory ulcerative colitis. Aliment Pharmacol Ther 2008;28:589-97.
-
(2008)
Aliment Pharmacol Ther
, vol.28
, pp. 589-597
-
-
Yamamoto, S.1
Nakase, H.2
Mikami, S.3
Inoue, S.4
Yoshino, T.5
Takeda, Y.6
-
12
-
-
28844473957
-
Infliximab for induction and maintenance therapy for ulcerative colitis
-
Rutgeerts P, Sandborn WJ, Feagan BG, Reinisch W, Olson A, Johanns J, et al. Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med 2005;353:2462-76.
-
(2005)
N Engl J Med
, vol.353
, pp. 2462-2476
-
-
Rutgeerts, P.1
Sandborn, W.J.2
Feagan, B.G.3
Reinisch, W.4
Olson, A.5
Johanns, J.6
-
13
-
-
53049091561
-
A randomized trial of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease
-
Sandborn WJ, Feagan BG, Fedorak RN, Scherl E, Fleisher MR, Katz S, et al. A randomized trial of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease. Gastroenterology 2008;135:1130-41.
-
(2008)
Gastroenterology
, vol.135
, pp. 1130-1141
-
-
Sandborn, W.J.1
Feagan, B.G.2
Fedorak, R.N.3
Scherl, E.4
Fleisher, M.R.5
Katz, S.6
-
15
-
-
74049124863
-
World Gastroenterology Organization practice guidelines for the diagnosis and management of IBD in 2010
-
Bernstein CN, Fried M, Krabshuis JH, Cohen H, Eliakim R, Fedail S, et al. World Gastroenterology Organization practice guidelines for the diagnosis and management of IBD in 2010. Inflamm Bowel Dis 2010;16:112-24.
-
(2010)
Inflamm Bowel Dis
, vol.16
, pp. 112-124
-
-
Bernstein, C.N.1
Fried, M.2
Krabshuis, J.H.3
Cohen, H.4
Eliakim, R.5
Fedail, S.6
-
17
-
-
67650667753
-
Temporal and spatial analysis of clinical and molecular parameters in dextran sodium sulfate induced colitis
-
Yan Y, Kolachala V, Dalmasso G, Nguyen H, Laroui H, Sitaraman SV, et al. Temporal and spatial analysis of clinical and molecular parameters in dextran sodium sulfate induced colitis. PLoS One 2009;4:1-8.
-
(2009)
PLoS One
, vol.4
, pp. 1-8
-
-
Yan, Y.1
Kolachala, V.2
Dalmasso, G.3
Nguyen, H.4
Laroui, H.5
Sitaraman, S.V.6
-
18
-
-
84862297537
-
Dextran sodium sulphate colitis mouse model: Traps and tricks
-
Perse M, Cerar A. Dextran sodium sulphate colitis mouse model: traps and tricks. J Biomed Biotechnol 2012;2012:718617.
-
(2012)
J Biomed Biotechnol
, vol.2012
-
-
Perse, M.1
Cerar, A.2
-
19
-
-
79151485447
-
Induction and activation of adaptive immune populations during acute and chronic phases of a murine model of experimental colitis
-
Hall LJ, Faivre E, Quinlan A, Shanahan F, Nally K, Melgar S. Induction and activation of adaptive immune populations during acute and chronic phases of a murine model of experimental colitis. Dig Dis Sci 2011;56:79-89.
-
(2011)
Dig Dis Sci
, vol.56
, pp. 79-89
-
-
Hall, L.J.1
Faivre, E.2
Quinlan, A.3
Shanahan, F.4
Nally, K.5
Melgar, S.6
-
20
-
-
75949091167
-
Overview of mouse models of inflammatory bowel disease and their use in drug discovery
-
Maxwell JR, Viney JL. Overview of mouse models of inflammatory bowel disease and their use in drug discovery. Curr Protoc Pharmacol 2009;47:5.57.1-5.57.19.
-
(2009)
Curr Protoc Pharmacol
, vol.47
, pp. 5571-55719
-
-
Maxwell, J.R.1
Viney, J.L.2
-
21
-
-
0035193261
-
Adenosine kinase inhibitor GP515 improves experimental colitis in mice
-
Siegmund B, Rieder F, Albrich S, Wolf K, Bidlingmaier C, Firestein GS, et al. Adenosine kinase inhibitor GP515 improves experimental colitis in mice. J Pharmacol Exp Ther 2001;296:99-105.
-
(2001)
J Pharmacol Exp Ther
, vol.296
, pp. 99-105
-
-
Siegmund, B.1
Rieder, F.2
Albrich, S.3
Wolf, K.4
Bidlingmaier, C.5
Firestein, G.S.6
-
22
-
-
77950797408
-
Clinical trial: Probiotic treatment of acute distal ulcerative colitis with rectally administered Escherichia coli Nissle 1917 (EcN)
-
Matthes H, Krummenerl T, Giensch M, Wolff C, Schulze J. Clinical trial: probiotic treatment of acute distal ulcerative colitis with rectally administered Escherichia coli Nissle 1917 (EcN). BMC Complement Altern Med 2010;10:13-20.
-
(2010)
BMC Complement Altern Med
, vol.10
, pp. 13-20
-
-
Matthes, H.1
Krummenerl, T.2
Giensch, M.3
Wolff, C.4
Schulze, J.5
-
23
-
-
84859801314
-
Double-blind, placebo-controlled trial of oral tacrolimus (FK506) in the management of hospitalized patients with steroid-refractory ulcerative colitis
-
Ogata H, Kato J, Hirai F, Hida N, Matsui T, Matsumoto T, et al. Double-blind, placebo-controlled trial of oral tacrolimus (FK506) in the management of hospitalized patients with steroid-refractory ulcerative colitis. Inflamm Bowel Dis 2012;18:803-8.
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 803-8
-
-
Ogata, H.1
Kato, J.2
Hirai, F.3
Hida, N.4
Matsui, T.5
Matsumoto, T.6
-
24
-
-
0642314146
-
Cytokine network in inflammatory bowel disease
-
Fuss IJ Cytokine network in inflammatory bowel disease. Curr Drug Targets Inflamm Allergy 2003;2:101-12.
-
(2003)
Curr Drug Targets Inflamm Allergy
, vol.2
, pp. 101-112
-
-
Fuss, I.J.1
-
25
-
-
77953233104
-
Classification of inflammation activity in ulcerative colitis by confocal laser endomicroscopy
-
Li CQ, Xie XJ, Yu T, Gu XM, Zuo XL, Zhou CJ, et al. Classification of inflammation activity in ulcerative colitis by confocal laser endomicroscopy. Am J Gastroenterol 2010;105:1391-6.
-
(2010)
Am J Gastroenterol
, vol.105
, pp. 1391-6
-
-
Li, C.Q.1
Xie, X.J.2
Yu, T.3
Gu, X.M.4
Zuo, X.L.5
Zhou, C.J.6
-
26
-
-
57449093379
-
Correlations among total colonoscopic findings, clinical symptoms, and laboratory markers in ulcerative colitis
-
Osada T, Ohkusa T, Okayasu I, Yoshida T, Hirai S, Beppu K, et al. Correlations among total colonoscopic findings, clinical symptoms, and laboratory markers in ulcerative colitis. J Gastroenterol Hepatol 2008;23(Suppl. 2):S262-7.
-
(2008)
J Gastroenterol Hepatol
, vol.23
, pp. S262-S267
-
-
Osada, T.1
Ohkusa, T.2
Okayasu, I.3
Yoshida, T.4
Hirai, S.5
Beppu, K.6
-
27
-
-
38349145438
-
Disease modifying effect of statins in dextran sulfate sodium model of mouse colitis
-
Kanagarajan N, Nam JH, Noah ZA, Murthy S. Disease modifying effect of statins in dextran sulfate sodium model of mouse colitis. Inflamm Res 2008;57:34-8.
-
(2008)
Inflamm Res
, vol.57
, pp. 34-8
-
-
Kanagarajan, N.1
Nam, J.H.2
Noah, Z.A.3
Murthy, S.4
-
28
-
-
0027486125
-
Location of tumour necrosis factor alpha by immunohistochemistry in chronic inflammatory bowel disease
-
Murch SH, Braegger CP, Walker-Smith JA, MacDonald TT. Location of tumour necrosis factor alpha by immunohistochemistry in chronic inflammatory bowel disease. Gut 1993;34:1705-9.
-
(1993)
Gut
, vol.34
, pp. 1705-9
-
-
Murch, S.H.1
Braegger, C.P.2
Walker-Smith, J.A.3
MacDonald, T.T.4
-
29
-
-
0034956578
-
Tumor necrosis factor-alpha in serum of patients with inflammatory bowel disease as measured by a highly sensitive immuno-PCR
-
Komatsu M, Kobayashi D, Saito K, Furuya D, Yagihashi A, Araake H, et al. Tumor necrosis factor-alpha in serum of patients with inflammatory bowel disease as measured by a highly sensitive immuno-PCR. Clin Chem 2001;47:1297-301.
-
(2001)
Clin Chem
, vol.47
, pp. 1297-1301
-
-
Komatsu, M.1
Kobayashi, D.2
Saito, K.3
Furuya, D.4
Yagihashi, A.5
Araake, H.6
-
30
-
-
84855674281
-
Long-term infliximab maintenance therapy for ulcerative colitis: The ACT-1 and -2 extension studies
-
Reinisch W, Sandborn WJ, Rutgeerts P, Feagan BG, Rachmilewitz D, Hanauer SB, et al. Long-term infliximab maintenance therapy for ulcerative colitis: the ACT-1 and -2 extension studies. Inflamm Bowel Dis 2012;18:201-11.
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 201-211
-
-
Reinisch, W.1
Sandborn, W.J.2
Rutgeerts, P.3
Feagan, B.G.4
Rachmilewitz, D.5
Hanauer, S.B.6
-
31
-
-
79955501236
-
PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice
-
Qiu W, Wu B, Wang X, Buchanan ME, Regueiro MD, Hartman DJ, et al. PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice. J Clin Invest 2011;121:1722-32.
-
(2011)
J Clin Invest
, vol.121
, pp. 1722-1732
-
-
Qiu, W.1
Wu, B.2
Wang, X.3
Buchanan, M.E.4
Regueiro, M.D.5
Hartman, D.J.6
-
33
-
-
43049135132
-
Validation of murine dextran sulfate sodium-induced colitis using four therapeutic agents for human inflammatory bowel disease
-
Melgar S, Karlsson L, Rehnstrom E, Karlsson A, Utkovic H, Jansson L, et al. Validation of murine dextran sulfate sodium-induced colitis using four therapeutic agents for human inflammatory bowel disease. Int Immunopharmacol 2008;8:836-44.
-
(2008)
Int Immunopharmacol
, vol.8
, pp. 836-844
-
-
Melgar, S.1
Karlsson, L.2
Rehnstrom, E.3
Karlsson, A.4
Utkovic, H.5
Jansson, L.6
-
34
-
-
84855698403
-
P-selectin glycoprotein ligand-1 is needed for sequential recruitment of T-helper 1 (Th1) and local generation of Th17 T cells in dextran sodium sulfate (DSS) colitis
-
Brown JB, Cheresh P, Zhang Z, Ryu H, Managlia E, Barrett TA. P-selectin glycoprotein ligand-1 is needed for sequential recruitment of T-helper 1 (Th1) and local generation of Th17 T cells in dextran sodium sulfate (DSS) colitis. Inflamm Bowel Dis 2012;18:323-32.
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 323-332
-
-
Brown, J.B.1
Cheresh, P.2
Zhang, Z.3
Ryu, H.4
Managlia, E.5
Barrett, T.A.6
-
35
-
-
84855692561
-
The intestinal anti-inflammatory effect of dersalazine sodium is related to a down-regulation in IL-17 production in experimental models of rodent colitis
-
Camuesco D, Rodriguez-Cabezas ME, Garrido-Mesa N, Cueto-Sola M, Bailon E, Comalada M, et al. The intestinal anti-inflammatory effect of dersalazine sodium is related to a down-regulation in IL-17 production in experimental models of rodent colitis. Br J Pharmacol 2012;165:729-40.
-
(2012)
Br J Pharmacol
, vol.165
, pp. 729-740
-
-
Camuesco, D.1
Rodriguez-Cabezas, M.E.2
Garrido-Mesa, N.3
Cueto-Sola, M.4
Bailon, E.5
Comalada, M.6
-
36
-
-
37349050665
-
Increased expression and activation of IL-12-induced Stat4 signaling in the mucosa of ulcerative colitis patients
-
Pang YH, Zheng CQ, Yang XZ, Zhang WJ. Increased expression and activation of IL-12-induced Stat4 signaling in the mucosa of ulcerative colitis patients. Cell Immunol 2007;248:115-20.
-
(2007)
Cell Immunol
, vol.248
, pp. 115-120
-
-
Pang, Y.H.1
Zheng, C.Q.2
Yang, X.Z.3
Zhang, W.J.4
|