Leukocytapheresis therapy for steroid-naïve patients with active ulcerative colitis: Its clinical efficacy and adverse effects compared with those of conventional steroid therapy

Journal of Gastroenterology and Hepatology (Australia)

Volumn 20, Issue 10, 2005, Pages 1567-1571

  Nishioka, Chiharu ^a   Aoyama, Nobuo ^a   Maekawa, Shuji ^a   Shirasaka, Daisuke ^a   Nakahara, Takako ^a   Tamura, Takao ^a   Fukagawa, Masashi ^a   Umezu, Michio ^a   Abe, Takaya ^a   Kasuga, Masato ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Adverse effects; Leukocytapheresis; Prednisolone; Ulcerative colitis

Indexed keywords

NAFAMSTAT MESILATE; PREDNISOLONE; STEROID; ANTIINFLAMMATORY AGENT;

ACNE; ADOLESCENT; ADULT; ARTICLE; CHILD; CYTAPHERESIS; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FATIGUE; FEMALE; HEADACHE; HUMAN; JAPAN; LEUKAPHERESIS; LEUKOCYTAPHERESIS; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; MOON FACE; PRIORITY JOURNAL; REMISSION; SLEEP DISORDER; STEROID THERAPY; STOMACH ULCER; ULCERATIVE COLITIS; BIOLOGICAL THERAPY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; MIDDLE AGED; TREATMENT OUTCOME;

ADOLESCENT; ADULT; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL THERAPY; CHILD; COLITIS, ULCERATIVE; FEMALE; HUMANS; LEUKAPHERESIS; MALE; MIDDLE AGED; PREDNISOLONE; REMISSION INDUCTION; TREATMENT OUTCOME;

EID: 33644666978     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2005.03907.x     Document Type: Article

References (25)

1. Babb R. Editorial: Corticosteroids in ulcerative colitis: A skeptical view. J. Clin. Gastroenterol. 1988 10 : 365 7.
2. Dujovne CA, Azarnoff DL. Clinical complications of corticosteroid therapy. Med. Clin. North Am. 1973 57 : 1331 42.
3. Shirokaze J. Leukocytaphresis using a leukocyte removal filter. Ther. Apher. 2002 6 : 261 6.
4. Hidaka T, Suzuki K, Matsuki Y et al. Filtration leukocytapheresis therapy in rheumatoid arthritis. Arthritis Rheum. 1999 42 : 431 7.
5. Sawada K, Ohnishi K, Fukui S et al. Leukocytapheresis therapy, performed with leukocyte removal filter, for inflammatory bowel disease. J. Gastroenterol. 1995 30 : 322 9.
6. Sawada K, Ohnishi K, Kosaka T et al. Leukocytapheresis therapy with leukocyte removal filter for inflammatory bowel disease. J. Gastroenterol. 1995 30 (Suppl. 8 124 7.
7. Sawada K, Ohnishi K, Kosaka T et al. Leukocytapheresis with leukocyte removal filter as new therapy for ulcerative colitis. Ther. Apher. 1997 1 : 207 11.
8. Yajima T, Takaishi H, Kanai T et al. Predictive factors of response to leukocytapheresis therapy for ulcerative colitis. Ther. Apher. 1998 2 : 115 19.
9. Sasaki M, Tsujikawa T, Fujiyama Y, Bamba T. Leukocytapheresis therapy for severe ulcerative colitis. Ther. Apher. 1998 2 : 101 4.
10. Truelove SC, Witts LJ. Cortisone in ulcerative colitis: Final report on a therapeutic trial. BMJ 1955 2 : 1041 8.
11. Yamaji K, Tsuda H, Hashimoto H. Current topics on cytapheresis technologies. Ther. Apher. 2001 5 : 287 92.
12. Aoyama T, Ino Y, Ozeki M et al. Pharmacological studies of FUT-175, nafamostat mesilate I. Inhibition of protease activity in in vitro and in vivo experiments. Jpn. J. Pharmacol. 1984 35 : 203 27.
13. Rachmilewitz D, on behalf of an international Study Group. Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: A randomized trial. BMJ 1989 298 : 82 6.
14. Ayabe T, Ashida T, Taniguchi M et al. A pilot study of centrifugal leukocyte apheresis for corticosteroid-resistant active ulcerative colitis. Intern. Med. 1997 36 : 322 6.
15. Hanai H, Watanabe F, Takeuchi K et al. Leukocyte absorptive apheresis for the treatment of active ulcerative colitis: A prospective, uncontrolled study. Clin. Gastroenterol. Hepatol. 2003 1 : 28 35.
16. Sawada K. Leukocytapheresis as an adjunct to conventional medication for inflammatory bowel disease. Dis. Colon Rectum 2003 46 (Suppl. 10 S66 77.
17. Sawada K, Ohnishi K, Kosaka T et al. Leukocytapheresis for inflammatory bowel disease. Intern. Med. 1996 77 : 287 92.
18. Jewell DP, Snook JA. Immunology of ulcerative colitis and Crohn's disease. In: Allan RN, Keighley MR, Alexander-Williams J, Hawkins C, eds. Inflammatory Bowel Disease. London : Churchill Livingstone, 1990; 127 46.
19. Fukunaga K, Fukuda Y, Sawada K et al. Poorly controlled ulcerative colitis by colectomy during remission induced by extracorporeal leukocyte removal therapy. J. Gastroenterol. 2003 38 : 684 9.
20. Sawada K, Muto T, Shimoyama T et al. Multicenter randomized controlled trial for the treatment of ulcerative colitis with a leukocytaphresis column. Curr. Pharm. Des. 2003 9 : 307 21.
21. Shimoyama T, Sawada K. Prospective multicenter randomized trial for treatment of ulcerative colitis by leukocytapheresis therapy with leukocyte removal filter. In: Annual Report of the Research Committee of Inflammatory Bowel Disease. Tokyo : Ministry of Health and Welfare of Japan, 1998; 126 9.
22. Jo Y, Matsumoto T, Mibu R, Iida M. Addition of leukocytapheresis to steroid therapy: Is it beneficial in recurrence of moderate-to-severe ulcerative colitis? Dis. Colon Rectum 2003 46 (Suppl. 10 S3 9.
23. Fagan EA, Dyck RF, Maton PN et al. Serum levels of C-reactive protein in Crohn's disease and ulcerative colitis. Eur. J. Clin. Invest. 1982 12 : 351 9.
24. Shinozaki M, Suzuki K, Sawada T, Tsuno N, Higuchi Y, Muto T. Steroid complications and surgery in intractable ulcerative colitis. J. Gastroenterol. 1998 33 : 196 200.
25. Siveke JT, Folwaczny C. Medical approach and future options in chronic active ulcerative colitis. Int. J. Colorectal Dis. 2004 19 : 297 307.