A new twist to an old tale: Novel insights into the differential toxicities of acetaminophen and its regioisomer N-acetyl-meta-aminophenol (AMAP)

Archives of Toxicology

Volumn 87, Issue 1, 2013, Pages 15-18

  Kenna, J Gerry ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; LIVER PROTEIN; METACETAMOL; MITOCHONDRIAL PROTEIN; PARACETAMOL;

COVALENT BOND; CYTOTOXICITY; DISEASE SEVERITY; DRUG METABOLISM; DRUG OVERDOSE; DRUG PROTEIN BINDING; HUMAN; ISOMER; LIVER CELL DAMAGE; LIVER METABOLISM; LIVER MITOCHONDRION; LIVER NECROSIS; LIVER TOXICITY; NONHUMAN; PRIORITY JOURNAL; REVIEW; SPECIES DIFFERENCE; TISSUE SECTION; TOXICITY TESTING;

ACETAMINOPHEN; AMINOPHENOLS; ANIMALS; CRICETINAE; HUMANS; LIVER; MICE; RATS; SPECIES SPECIFICITY; TOXICITY TESTS;

EID: 84872308343     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0945-9     Document Type: Review

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