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Volumn 97, Issue 1, 2013, Pages 111-122

CAP, a new human suspension cell line for influenza virus production

Author keywords

Amniocytes; Bioreactor; Glycosylation; Human cell line; Influenza virus; Suspension growth; Trypsin; Vaccine production

Indexed keywords

AMNIOCYTES; HUMAN CELL LINES; INFLUENZA VIRUS; TRYPSIN; VACCINE PRODUCTION;

EID: 84872306499     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-012-4238-2     Document Type: Article
Times cited : (40)

References (46)
  • 1
    • 79954576030 scopus 로고    scopus 로고
    • Bioprocess optimization for cell culture based influenza vaccine production
    • 10.1016/j.vaccine.2011.01.081 10.1016/j.vaccine.2011.01.081 1:CAS:528:DC%2BC3MXkvVWjsbw%3D
    • Aggarwal K, Jing F, Maranga L, Liu J (2011) Bioprocess optimization for cell culture based influenza vaccine production. Vaccine 29(17):3320-3328. doi: 10.1016/j.vaccine.2011.01.081
    • (2011) Vaccine , vol.29 , Issue.17 , pp. 3320-3328
    • Aggarwal, K.1    Jing, F.2    Maranga, L.3    Liu, J.4
  • 2
    • 70349270680 scopus 로고    scopus 로고
    • Conversion of MDCK cell line to suspension culture by transfecting with human siat7e gene and its application for influenza virus production
    • 10.1073/pnas.0905912106 10.1073/pnas.0905912106 1:CAS:528: DC%2BD1MXhtFGrt77O
    • Chu C, Lugovtsev V, Golding H, Betenbaugh M, Shiloach J (2009) Conversion of MDCK cell line to suspension culture by transfecting with human siat7e gene and its application for influenza virus production. Proc Natl Acad Sci U S A 106(35):14802-14807. doi: 10.1073/pnas.0905912106
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.35 , pp. 14802-14807
    • Chu, C.1    Lugovtsev, V.2    Golding, H.3    Betenbaugh, M.4    Shiloach, J.5
  • 3
    • 77957822721 scopus 로고    scopus 로고
    • Production and antigenic properties of influenza virus from suspension MDCK-siat7e cells in a bench-scale bioreactor
    • 10.1016/j.vaccine.2010.08.059 10.1016/j.vaccine.2010.08.059 1:CAS:528:DC%2BC3cXht1KqtrrM
    • Chu C, Lugovtsev V, Lewis A, Betenbaugh M, Shiloach J (2010) Production and antigenic properties of influenza virus from suspension MDCK-siat7e cells in a bench-scale bioreactor. Vaccine 28(44):7193-7201. doi: 10.1016/j.vaccine. 2010.08.059
    • (2010) Vaccine , vol.28 , Issue.44 , pp. 7193-7201
    • Chu, C.1    Lugovtsev, V.2    Lewis, A.3    Betenbaugh, M.4    Shiloach, J.5
  • 5
    • 0032145579 scopus 로고    scopus 로고
    • Effects of host-dependent glycosylation of hemagglutinin on receptor-binding properties on H1N1 human influenza A virus grown in MDCK cells and in embryonated eggs
    • 10.1006/viro.1998.9224 1:CAS:528:DyaK1cXlt1ehtrw%3D
    • Gambaryan AS, Marinina VP, Tuzikov AB, Bovin NV, Rudneva IA, Sinitsyn BV, Shilov AA, Matrosovich MN (1998) Effects of host-dependent glycosylation of hemagglutinin on receptor-binding properties on H1N1 human influenza A virus grown in MDCK cells and in embryonated eggs. Virology 247(2):170-177
    • (1998) Virology , vol.247 , Issue.2 , pp. 170-177
    • Gambaryan, A.S.1    Marinina, V.P.2    Tuzikov, A.B.3    Bovin, N.V.4    Rudneva, I.A.5    Sinitsyn, B.V.6    Shilov, A.A.7    Matrosovich, M.N.8
  • 6
    • 38949155404 scopus 로고    scopus 로고
    • Vaccine production - State of the art and future needs in upstream processing
    • R. Pörtner (eds) Humana Press Inc. Totowa
    • Genzel Y, Reichl U (2007) Vaccine production - state of the art and future needs in upstream processing. In: Pörtner R (ed) Methods in biotechnology: animal cell biotechnology - methods and protocols. Humana Press Inc., Totowa, pp 457-473
    • (2007) Methods in Biotechnology: Animal Cell Biotechnology - Methods and Protocols , pp. 457-473
    • Genzel, Y.1    Reichl, U.2
  • 7
    • 73849115748 scopus 로고    scopus 로고
    • Continuous cell lines as a production system for influenza vaccines
    • 10.1586/erv.09.128 10.1586/erv.09.128 1:CAS:528:DC%2BD1MXhsV2jtb7J
    • Genzel Y, Reichl U (2009) Continuous cell lines as a production system for influenza vaccines. Expert Rev Vaccines 8(12):1681-1692. doi: 10.1586/erv.09.128
    • (2009) Expert Rev Vaccines , vol.8 , Issue.12 , pp. 1681-1692
    • Genzel, Y.1    Reichl, U.2
  • 8
    • 2442437845 scopus 로고    scopus 로고
    • Metabolism of MDCK cells during cell growth and influenza virus production in large-scale microcarrier culture
    • 10.1016/j.vaccine.2003.11.041 10.1016/j.vaccine.2003.11.041 1:CAS:528:DC%2BD2cXktV2ltr4%3D
    • Genzel Y, Behrendt I, Konig S, Sann H, Reichl U (2004) Metabolism of MDCK cells during cell growth and influenza virus production in large-scale microcarrier culture. Vaccine 22(17-18):2202-2208. doi: 10.1016/j.vaccine.2003. 11.041
    • (2004) Vaccine , vol.22 , Issue.17-18 , pp. 2202-2208
    • Genzel, Y.1    Behrendt, I.2    Konig, S.3    Sann, H.4    Reichl, U.5
  • 9
    • 33645046102 scopus 로고    scopus 로고
    • Serum-free influenza virus production avoiding washing steps and medium exchange in large-scale microcarrier culture
    • 10.1016/j.vaccine.2006.01.019 10.1016/j.vaccine.2006.01.019 1:CAS:528:DC%2BD28XivFSjs78%3D
    • Genzel Y, Fischer M, Reichl U (2006) Serum-free influenza virus production avoiding washing steps and medium exchange in large-scale microcarrier culture. Vaccine 24(16):3261-3272. doi: 10.1016/j.vaccine.2006.01. 019
    • (2006) Vaccine , vol.24 , Issue.16 , pp. 3261-3272
    • Genzel, Y.1    Fischer, M.2    Reichl, U.3
  • 10
    • 77956229617 scopus 로고    scopus 로고
    • MDCK and Vero cells for influenza virus vaccine production: A one-to-one comparison up to lab-scale bioreactor cultivation
    • 10.1007/s00253-010-2742-9 10.1007/s00253-010-2742-9 1:CAS:528: DC%2BC3cXhtVGgt77O
    • Genzel Y, Dietzsch C, Rapp E, Schwarzer J, Reichl U (2010) MDCK and Vero cells for influenza virus vaccine production: a one-to-one comparison up to lab-scale bioreactor cultivation. Appl Microbiol Biotechnol 88(2):461-475. doi: 10.1007/s00253-010-2742-9
    • (2010) Appl Microbiol Biotechnol , vol.88 , Issue.2 , pp. 461-475
    • Genzel, Y.1    Dietzsch, C.2    Rapp, E.3    Schwarzer, J.4    Reichl, U.5
  • 11
    • 77955683344 scopus 로고    scopus 로고
    • Production of cell culture (MDCK) derived live attenuated influenza vaccine (LAIV) in a fully disposable platform process
    • 10.1002/bit.22753 10.1002/bit.22753 1:CAS:528:DC%2BC3cXosVWhs7g%3D
    • George M, Farooq M, Dang T, Cortes B, Liu J, Maranga L (2010) Production of cell culture (MDCK) derived live attenuated influenza vaccine (LAIV) in a fully disposable platform process. Biotechnol Bioeng 106(6):906-917. doi: 10.1002/bit.22753
    • (2010) Biotechnol Bioeng , vol.106 , Issue.6 , pp. 906-917
    • George, M.1    Farooq, M.2    Dang, T.3    Cortes, B.4    Liu, J.5    Maranga, L.6
  • 12
    • 0028999814 scopus 로고
    • Replication of influenza A viruses in a green monkey kidney continuous cell line (Vero)
    • 10.1093/infdis/172.1.250 1:STN:280:DyaK2MzhvVGgtA%3D%3D
    • Govorkova EA, Kaverin NV, Gubareva LV, Meignier B, Webster RG (1995) Replication of influenza A viruses in a green monkey kidney continuous cell line (Vero). J Infect Dis 172(1):250-253
    • (1995) J Infect Dis , vol.172 , Issue.1 , pp. 250-253
    • Govorkova, E.A.1    Kaverin, N.V.2    Gubareva, L.V.3    Meignier, B.4    Webster, R.G.5
  • 13
    • 0017710978 scopus 로고
    • Characteristics of a human cell line transformed by DNA from human adenovirus type 5
    • 10.1099/0022-1317-36-1-59 1:STN:280:DyaE2s3ivFGmtQ%3D%3D
    • Graham FL, Smiley J, Russell WC, Nairn R (1977) Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol 36(1):59-74
    • (1977) J Gen Virol , vol.36 , Issue.1 , pp. 59-74
    • Graham, F.L.1    Smiley, J.2    Russell, W.C.3    Nairn, R.4
  • 14
    • 79952409698 scopus 로고    scopus 로고
    • Safety of MDCK cell culture-based influenza vaccines
    • 10.2217/fmb.10.161 10.2217/fmb.10.161
    • Gregersen JP, Schmitt HJ, Trusheim H, Broker M (2011) Safety of MDCK cell culture-based influenza vaccines. Future Microbiol 6(2):143-152. doi: 10.2217/fmb.10.161
    • (2011) Future Microbiol , vol.6 , Issue.2 , pp. 143-152
    • Gregersen, J.P.1    Schmitt, H.J.2    Trusheim, H.3    Broker, M.4
  • 15
    • 58249123674 scopus 로고    scopus 로고
    • An avian cell line designed for production of highly attenuated viruses
    • 10.1016/j.vaccine.2008.11.066 10.1016/j.vaccine.2008.11.066 1:CAS:528:DC%2BD1MXmvVOgsg%3D%3D
    • Jordan I, Vos A, Beilfuss S, Neubert A, Breul S, Sandig V (2009) An avian cell line designed for production of highly attenuated viruses. Vaccine 27(5):748-756. doi: 10.1016/j.vaccine.2008.11.066
    • (2009) Vaccine , vol.27 , Issue.5 , pp. 748-756
    • Jordan, I.1    Vos, A.2    Beilfuss, S.3    Neubert, A.4    Breul, S.5    Sandig, V.6
  • 16
    • 41949085484 scopus 로고    scopus 로고
    • Monitoring influenza virus content in vaccine production: Precise assays for the quantitation of hemagglutination and neuraminidase activity
    • 10.1016/j.biologicals.2007.10.002 1:CAS:528:DC%2BD1cXkvVOrtbg%3D
    • Kalbfuss B, Knochlein A, Krober T, Reichl U (2008) Monitoring influenza virus content in vaccine production: precise assays for the quantitation of hemagglutination and neuraminidase activity. Biologicals 36(3):145-161
    • (2008) Biologicals , vol.36 , Issue.3 , pp. 145-161
    • Kalbfuss, B.1    Knochlein, A.2    Krober, T.3    Reichl, U.4
  • 17
    • 0028926664 scopus 로고
    • Impairment of multicycle influenza virus growth in Vero (WHO) cells by loss of trypsin activity
    • 1:CAS:528:DyaK2MXksVSls74%3D
    • Kaverin NV, Webster RG (1995) Impairment of multicycle influenza virus growth in Vero (WHO) cells by loss of trypsin activity. J Virol 69(4):2700-2703
    • (1995) J Virol , vol.69 , Issue.4 , pp. 2700-2703
    • Kaverin, N.V.1    Webster, R.G.2
  • 18
    • 77953133120 scopus 로고    scopus 로고
    • Scalable production of influenza virus in HEK-293 cells for efficient vaccine manufacturing
    • 10.1016/j.vaccine.2010.03.029 10.1016/j.vaccine.2010.03.029
    • Le Ru A, Jacob D, Transfiguracion J, Ansorge S, Henry O, Kamen AA (2010) Scalable production of influenza virus in HEK-293 cells for efficient vaccine manufacturing. Vaccine 28(21):3661-3671. doi: 10.1016/j.vaccine.2010.03.029
    • (2010) Vaccine , vol.28 , Issue.21 , pp. 3661-3671
    • Le Ru, A.1    Jacob, D.2    Transfiguracion, J.3    Ansorge, S.4    Henry, O.5    Kamen, A.A.6
  • 19
    • 67650430190 scopus 로고    scopus 로고
    • New avian suspension cell lines provide production of influenza virus and MVA in serum-free media: Studies on growth, metabolism and virus propagation
    • 10.1016/j.vaccine.2009.05.083 10.1016/j.vaccine.2009.05.083 1:CAS:528:DC%2BD1MXos12rtr8%3D
    • Lohr V, Rath A, Genzel Y, Jordan I, Sandig V, Reichl U (2009) New avian suspension cell lines provide production of influenza virus and MVA in serum-free media: studies on growth, metabolism and virus propagation. Vaccine 27(36):4975-4982. doi: 10.1016/j.vaccine.2009.05.083
    • (2009) Vaccine , vol.27 , Issue.36 , pp. 4975-4982
    • Lohr, V.1    Rath, A.2    Genzel, Y.3    Jordan, I.4    Sandig, V.5    Reichl, U.6
  • 20
    • 77955656086 scopus 로고    scopus 로고
    • A new MDCK suspension line cultivated in a fully defined medium in stirred-tank and wave bioreactor
    • 10.1016/j.vaccine.2010.07.004 10.1016/j.vaccine.2010.07.004 1:CAS:528:DC%2BC3cXhtVaqu7%2FN
    • Lohr V, Genzel Y, Behrendt I, Scharfenberg K, Reichl U (2010) A new MDCK suspension line cultivated in a fully defined medium in stirred-tank and wave bioreactor. Vaccine 28(38):6256-6264. doi: 10.1016/j.vaccine.2010.07.004
    • (2010) Vaccine , vol.28 , Issue.38 , pp. 6256-6264
    • Lohr, V.1    Genzel, Y.2    Behrendt, I.3    Scharfenberg, K.4    Reichl, U.5
  • 22
    • 39549094207 scopus 로고    scopus 로고
    • Purification and cDNA cloning of a novel protease inhibitor secreted into culture supernatant by MDCK cells
    • 10.1016/j.biologicals.2007.07.004 10.1016/j.biologicals.2007.07.004 1:CAS:528:DC%2BD1cXislSru7c%3D
    • Nishiyama K, Sugawara K, Nouchi T, Kawano N, Soejima K, Abe S, Mizokami H (2008) Purification and cDNA cloning of a novel protease inhibitor secreted into culture supernatant by MDCK cells. Biologicals 36(2):122-133. doi: 10.1016/j.biologicals.2007.07.004
    • (2008) Biologicals , vol.36 , Issue.2 , pp. 122-133
    • Nishiyama, K.1    Sugawara, K.2    Nouchi, T.3    Kawano, N.4    Soejima, K.5    Abe, S.6    Mizokami, H.7
  • 23
    • 70350154349 scopus 로고    scopus 로고
    • Suspension-Vero cell cultures as a platform for viral vaccine production
    • 10.1016/j.vaccine.2009.06.020 10.1016/j.vaccine.2009.06.020 1:CAS:528:DC%2BD1MXhtlSqsr3E
    • Paillet C, Forno G, Kratje R, Etcheverrigaray M (2009) Suspension-Vero cell cultures as a platform for viral vaccine production. Vaccine 27(46):6464-6467. doi: 10.1016/j.vaccine.2009.06.020
    • (2009) Vaccine , vol.27 , Issue.46 , pp. 6464-6467
    • Paillet, C.1    Forno, G.2    Kratje, R.3    Etcheverrigaray, M.4
  • 24
    • 80052462973 scopus 로고    scopus 로고
    • Statistical optimization of influenza H1N1 production from batch cultures of suspension Vero cells (sVero)
    • 10.1016/j.vaccine.2011.07.016 10.1016/j.vaccine.2011.07.016 1:CAS:528:DC%2BC3MXhtFKjtr3K
    • Paillet C, Forno G, Soldano N, Kratje R, Etcheverrigaray M (2011) Statistical optimization of influenza H1N1 production from batch cultures of suspension Vero cells (sVero). Vaccine 29(41):7212-7217. doi: 10.1016/j.vaccine.2011.07.016
    • (2011) Vaccine , vol.29 , Issue.41 , pp. 7212-7217
    • Paillet, C.1    Forno, G.2    Soldano, N.3    Kratje, R.4    Etcheverrigaray, M.5
  • 25
    • 0035925715 scopus 로고    scopus 로고
    • The human cell line PER.C6 provides a new manufacturing system for the production of influenza vaccines
    • 10.1016/S0264-410X(00)00508-9 1:CAS:528:DC%2BD3MXitVOit7s%3D
    • Pau MG, Ophorst C, Koldijk MH, Schouten G, Mehtali M, Uytdehaag F (2001) The human cell line PER.C6 provides a new manufacturing system for the production of influenza vaccines. Vaccine 19(17-19):2716-2721
    • (2001) Vaccine , vol.19 , Issue.17-19 , pp. 2716-2721
    • Pau, M.G.1    Ophorst, C.2    Koldijk, M.H.3    Schouten, G.4    Mehtali, M.5    Uytdehaag, F.6
  • 26
    • 80052145378 scopus 로고    scopus 로고
    • Metabolic and kinetic analyses of influenza production in perfusion HEK293 cell culture
    • 10.1186/1472-6750-11-84 10.1186/1472-6750-11-84 1:CAS:528: DC%2BC3MXht1Wrur%2FF
    • Petiot E, Jacob D, Lanthier S, Lohr V, Ansorge S, Kamen AA (2011) Metabolic and kinetic analyses of influenza production in perfusion HEK293 cell culture. BMC Biotechnol 11:84. doi: 10.1186/1472-6750-11-84
    • (2011) BMC Biotechnol , vol.11 , pp. 84
    • Petiot, E.1    Jacob, D.2    Lanthier, S.3    Lohr, V.4    Ansorge, S.5    Kamen, A.A.6
  • 27
    • 84934437867 scopus 로고    scopus 로고
    • Glycosylation as a target for recognition of influenza viruses by the innate immune system
    • 10.1007/978-0-387-71767-8-20 10.1007/978-0-387-71767-8-20
    • Reading PC, Tate MD, Pickett DL, Brooks AG (2007) Glycosylation as a target for recognition of influenza viruses by the innate immune system. Adv Exp Med Biol 598:279-292. doi: 10.1007/978-0-387-71767-8-20
    • (2007) Adv Exp Med Biol , vol.598 , pp. 279-292
    • Reading, P.C.1    Tate, M.D.2    Pickett, D.L.3    Brooks, A.G.4
  • 28
    • 0023261116 scopus 로고
    • Structural changes in the haemagglutinin which accompany egg adaptation of an influenza A(H1N1) virus
    • 10.1016/0042-6822(87)90040-7 1:CAS:528:DyaL2sXlslersbY%3D
    • Robertson JS, Bootman JS, Newman R, Oxford JS, Daniels RS, Webster RG, Schild GC (1987) Structural changes in the haemagglutinin which accompany egg adaptation of an influenza A(H1N1) virus. Virology 160(1):31-37
    • (1987) Virology , vol.160 , Issue.1 , pp. 31-37
    • Robertson, J.S.1    Bootman, J.S.2    Newman, R.3    Oxford, J.S.4    Daniels, R.S.5    Webster, R.G.6    Schild, G.C.7
  • 30
    • 84855790406 scopus 로고    scopus 로고
    • Impact of influenza virus adaptation status on HA N-glycosylation patterns in cell culture-based vaccine production
    • 10.1080/07328303.2011.604454 10.1080/07328303.2011.604454
    • Rödig JV, Rapp E, Djeljadini S, Lohr V, Genzel Y, Jordan I, Sandig V, Reichl U (2011a) Impact of influenza virus adaptation status on HA N-glycosylation patterns in cell culture-based vaccine production. J Carbohydr Chem 30(4-6):281-290. doi: 10.1080/07328303.2011.604454
    • (2011) J Carbohydr Chem , vol.30 , Issue.4-6 , pp. 281-290
    • Rödig, J.V.1    Rapp, E.2    Djeljadini, S.3    Lohr, V.4    Genzel, Y.5    Jordan, I.6    Sandig, V.7    Reichl, U.8
  • 31
    • 82855172168 scopus 로고    scopus 로고
    • Impact of host cell line adaptation on quasispecies composition and glycosylation of influenza A virus hemagglutinin
    • 10.1371/journal.pone.0027989 10.1371/journal.pone.0027989
    • Rödig JV, Rapp E, Höper D, Genzel Y, Reichl U (2011b) Impact of host cell line adaptation on quasispecies composition and glycosylation of influenza A virus hemagglutinin. PLoS One 6(12):e27989. doi: 10.1371/journal.pone.0027989
    • (2011) PLoS One , vol.6 , Issue.12 , pp. 27989
    • Rödig, J.V.1    Rapp, E.2    Höper, D.3    Genzel, Y.4    Reichl, U.5
  • 33
    • 0034633740 scopus 로고    scopus 로고
    • Efficient transformation of primary human amniocytes by E1 functions of Ad5: Generation of new cell lines for adenoviral vector production
    • 10.1089/104303400750001417 10.1089/104303400750001417 1:CAS:528:DC%2BD3cXnsFOntbs%3D
    • Schiedner G, Hertel S, Kochanek S (2000) Efficient transformation of primary human amniocytes by E1 functions of Ad5: generation of new cell lines for adenoviral vector production. Hum Gene Ther 11(15):2105-2116. doi: 10.1089/104303400750001417
    • (2000) Hum Gene Ther , vol.11 , Issue.15 , pp. 2105-2116
    • Schiedner, G.1    Hertel, S.2    Kochanek, S.3
  • 34
    • 40449122158 scopus 로고    scopus 로고
    • Efficient and reproducible generation of high-expressing, stable human cell lines without need for antibiotic selection
    • 10.1186/1472-6750-8-13 10.1186/1472-6750-8-13
    • Schiedner G, Hertel S, Bialek C, Kewes H, Waschutza G, Volpers C (2008) Efficient and reproducible generation of high-expressing, stable human cell lines without need for antibiotic selection. BMC Biotechnol 8:13. doi: 10.1186/1472-6750-8-13
    • (2008) BMC Biotechnol , vol.8 , pp. 13
    • Schiedner, G.1    Hertel, S.2    Bialek, C.3    Kewes, H.4    Waschutza, G.5    Volpers, C.6
  • 35
    • 56849090276 scopus 로고    scopus 로고
    • N-glycan analysis by CGE-LIF: Profiling influenza A virus hemagglutinin N-glycosylation during vaccine production
    • 10.1002/elps.200800042 10.1002/elps.200800042 1:CAS:528: DC%2BD1cXhsVyqurjK
    • Schwarzer J, Rapp E, Reichl U (2008) N-glycan analysis by CGE-LIF: profiling influenza A virus hemagglutinin N-glycosylation during vaccine production. Electrophoresis 29(20):4203-4214. doi: 10.1002/elps.200800042
    • (2008) Electrophoresis , vol.29 , Issue.20 , pp. 4203-4214
    • Schwarzer, J.1    Rapp, E.2    Reichl, U.3
  • 36
    • 67649625767 scopus 로고    scopus 로고
    • Glycan analysis in cell culture-based influenza vaccine production: Influence of host cell line and virus strain on the glycosylation pattern of viral hemagglutinin
    • 10.1016/j.vaccine.2009.04.076 10.1016/j.vaccine.2009.04.076 1:CAS:528:DC%2BD1MXnsV2rs7k%3D
    • Schwarzer J, Rapp E, Hennig R, Genzel Y, Jordan I, Sandig V, Reichl U (2009) Glycan analysis in cell culture-based influenza vaccine production: influence of host cell line and virus strain on the glycosylation pattern of viral hemagglutinin. Vaccine 27(32):4325-4336. doi: 10.1016/j.vaccine.2009.04. 076
    • (2009) Vaccine , vol.27 , Issue.32 , pp. 4325-4336
    • Schwarzer, J.1    Rapp, E.2    Hennig, R.3    Genzel, Y.4    Jordan, I.5    Sandig, V.6    Reichl, U.7
  • 37
    • 77954161529 scopus 로고    scopus 로고
    • High yields of influenza A virus in Madin-Darby canine kidney cells are promoted by an insufficient interferon-induced antiviral state
    • 10.1099/vir.0.020370-0 10.1099/vir.0.020370-0 1:CAS:528: DC%2BC3cXpsVOntr0%3D
    • Seitz C, Frensing T, Hoper D, Kochs G, Reichl U (2010) High yields of influenza A virus in Madin-Darby canine kidney cells are promoted by an insufficient interferon-induced antiviral state. J Gen Virol 91(Pt 7):1754-1763. doi: 10.1099/vir.0.020370-0
    • (2010) J Gen Virol , vol.91 , Issue.PART 7 , pp. 1754-1763
    • Seitz, C.1    Frensing, T.2    Hoper, D.3    Kochs, G.4    Reichl, U.5
  • 38
    • 84856287312 scopus 로고    scopus 로고
    • Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response
    • 10.1007/s00253-011-3569-8 10.1007/s00253-011-3569-8 1:CAS:528: DC%2BC38XntlGmtQ%3D%3D
    • Seitz C, Isken B, Heynisch B, Rettkowski M, Frensing T, Reichl U (2012) Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response. Appl Microbiol Biotechnol 93(2):601-611. doi: 10.1007/s00253-011-3569-8
    • (2012) Appl Microbiol Biotechnol , vol.93 , Issue.2 , pp. 601-611
    • Seitz, C.1    Isken, B.2    Heynisch, B.3    Rettkowski, M.4    Frensing, T.5    Reichl, U.6
  • 39
    • 0036618178 scopus 로고    scopus 로고
    • Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells
    • 10.1096/fj.01-0995fje 1:CAS:528:DC%2BD38Xktl2rs78%3D
    • Shaw G, Morse S, Ararat M, Graham FL (2002) Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells. FASEB J Off Publ Fed Am Soc Exp Biol 16(8):869-871. doi: 10.1096/fj.01-0995fje
    • (2002) FASEB J off Publ Fed Am Soc Exp Biol , vol.16 , Issue.8 , pp. 869-871
    • Shaw, G.1    Morse, S.2    Ararat, M.3    Graham, F.L.4
  • 40
    • 0031572250 scopus 로고    scopus 로고
    • Rescue of a viral gene from Vero cells latently infected with influenza virus B/Lee/40
    • 10.1006/viro.1997.8716 1:CAS:528:DyaK2sXmsVWguro%3D
    • Tobita K, Tanaka T, Hayase Y (1997) Rescue of a viral gene from Vero cells latently infected with influenza virus B/Lee/40. Virology 236(1):130-136
    • (1997) Virology , vol.236 , Issue.1 , pp. 130-136
    • Tobita, K.1    Tanaka, T.2    Hayase, Y.3
  • 41
    • 80054748686 scopus 로고    scopus 로고
    • Adaptation of high-growth influenza H5N1 vaccine virus in Vero cells: Implications for pandemic preparedness
    • 10.1371/journal.pone.0024057 10.1371/journal.pone.0024057 1:CAS:528:DC%2BC3MXhsVSgtr7N
    • Tseng YF, Hu AY, Huang ML, Yeh WZ, Weng TC, Chen YS, Chong P, Lee MS (2011) Adaptation of high-growth influenza H5N1 vaccine virus in Vero cells: implications for pandemic preparedness. PLoS One 6(10):e24057. doi: 10.1371/journal.pone.0024057
    • (2011) PLoS One , vol.6 , Issue.10 , pp. 24057
    • Tseng, Y.F.1    Hu, A.Y.2    Huang, M.L.3    Yeh, W.Z.4    Weng, T.C.5    Chen, Y.S.6    Chong, P.7    Lee, M.S.8
  • 42
    • 78650569516 scopus 로고    scopus 로고
    • Adaptation of a Madin-Darby canine kidney cell line to suspension growth in serum-free media and comparison of its ability to produce avian influenza virus to Vero and BHK21 cell lines
    • 10.1016/j.jviromet.2010.09.029 10.1016/j.jviromet.2010.09.029
    • van Wielink R, Kant-Eenbergen HC, Harmsen MM, Martens DE, Wijffels RH, Coco-Martin JM (2011) Adaptation of a Madin-Darby canine kidney cell line to suspension growth in serum-free media and comparison of its ability to produce avian influenza virus to Vero and BHK21 cell lines. J Virol Methods 171(1):53-60. doi: 10.1016/j.jviromet.2010.09.029
    • (2011) J Virol Methods , vol.171 , Issue.1 , pp. 53-60
    • Van Wielink, R.1    Kant-Eenbergen, H.C.2    Harmsen, M.M.3    Martens, D.E.4    Wijffels, R.H.5    Coco-Martin, J.M.6
  • 43
    • 67650713700 scopus 로고    scopus 로고
    • Quantitative analysis of cellular proteome alterations in human influenza A virus-infected mammalian cell lines
    • doi: 10.1002/pmic.200800893
    • Vester D, Rapp E, Gade D, Genzel Y, Reichl U (2009) Quantitative analysis of cellular proteome alterations in human influenza A virus-infected mammalian cell lines. Proteomics. doi: 10.1002/pmic.200800893
    • (2009) Proteomics
    • Vester, D.1    Rapp, E.2    Gade, D.3    Genzel, Y.4    Reichl, U.5
  • 44
    • 77954657137 scopus 로고    scopus 로고
    • Virus-host cell interactions in vaccine production cell lines infected with different human influenza A virus variants: A proteomic approach
    • 10.1016/j.jprot.2010.04.006 10.1016/j.jprot.2010.04.006 1:CAS:528:DC%2BC3cXovFygtL4%3D
    • Vester D, Rapp E, Kluge S, Genzel Y, Reichl U (2010) Virus-host cell interactions in vaccine production cell lines infected with different human influenza A virus variants: a proteomic approach. J Proteomics 73(9):1656-1669. doi: 10.1016/j.jprot.2010.04.006
    • (2010) J Proteomics , vol.73 , Issue.9 , pp. 1656-1669
    • Vester, D.1    Rapp, E.2    Kluge, S.3    Genzel, Y.4    Reichl, U.5
  • 45
    • 77049195843 scopus 로고
    • Incomplete forms of influenza virus
    • 10.1016/S0065-3527(08)60529-1
    • Von Magnus P (1954) Incomplete forms of influenza virus. Adv Virus Res 2:59-79
    • (1954) Adv Virus Res , vol.2 , pp. 59-79
    • Von Magnus, P.1
  • 46
    • 67649979804 scopus 로고    scopus 로고
    • Structural and evolutionary characteristics of HA, NA, NS and M genes of clinical influenza A/H3N2 viruses passaged in human and canine cells
    • 10.1016/j.jcv.2009.05.030 10.1016/j.jcv.2009.05.030 1:CAS:528: DC%2BD1MXosVahtbY%3D
    • Zhirnov OP, Vorobjeva IV, Saphonova OA, Poyarkov SV, Ovcharenko AV, Anhlan D, Malyshev NA (2009) Structural and evolutionary characteristics of HA, NA, NS and M genes of clinical influenza A/H3N2 viruses passaged in human and canine cells. J Clin Virol 45(4):322-333. doi: 10.1016/j.jcv.2009.05.030
    • (2009) J Clin Virol , vol.45 , Issue.4 , pp. 322-333
    • Zhirnov, O.P.1    Vorobjeva, I.V.2    Saphonova, O.A.3    Poyarkov, S.V.4    Ovcharenko, A.V.5    Anhlan, D.6    Malyshev, N.A.7


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