The human cell line PER.C6 provides a new manufacturing system for the production of influenza vaccines

Vaccine

Volumn 19, Issue 17-19, 2001, Pages 2716-2721

  Pau, M G ^a   Ophorst, C ^a   Koldijk, M H ^a   Schouten, G ^a   Mehtali, M ^a   Uytdehaag, F ^a  

^a CRUCELL HOLLAND BV   (Netherlands)

Author keywords

Influenza; PER.C6; Vaccine

Indexed keywords

INFLUENZA VACCINE;

ANTIGENICITY; CELL CULTURE; CELL STRAIN; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOGENICITY; INFLUENZA VIRUS A; INFLUENZA VIRUS B; LIFE CYCLE; NONHUMAN; PRIORITY JOURNAL; VACCINE PRODUCTION; VIROGENESIS; VIRUS INFECTIVITY; VIRUS REPLICATION; ZYGOTE;

ANIMALS; ANTIGENS, VIRAL; BIOREACTORS; CELL LINE; CHICKENS; EDETIC ACID; HEMAGGLUTININS, VIRAL; HUMANS; INFLUENZA VACCINES; ORTHOMYXOVIRIDAE; TRYPSIN; VIRUS CULTIVATION; VIRUS REPLICATION;

EID: 0035925715     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(00)00508-9     Document Type: Conference Paper

References (9)

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4. New helper cells and matched early region 1-deleted adenovirus vectors prevent generation of replication-competent adenoviruses
5. Effects of egg-adaptation on the receptor-binding properties of human influenza A and B viruses
6. Characterization of high-growth reassortant influenza viruses generated in MDCK cells cultured in serum-free medium
7. Selection of receptor-binding variants of human influenza A and B viruses in baby hamster kidney cells
8. Alteration of terminal glycosylation sequences on N-linked oligosaccharides of Chinese hamster ovary cells by expression of beta-galactoside alpha 2,6-sialyltransferase