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Volumn 33, Issue 1, 2013, Pages 121-128

Chondrogenesis from umbilical cord blood cells stimulated with BMP-2 and BMP-6

Author keywords

Chondrogenesis; Collagen; Cord blood; Differentiation; Mesenchymal stem cells

Indexed keywords

AGGRECAN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 6; COLLAGEN TYPE 2;

EID: 84872294637     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-011-2328-6     Document Type: Article
Times cited : (23)

References (45)
  • 2
    • 27744573156 scopus 로고    scopus 로고
    • Potential application for mesenchymal stem cells in the treatment of cardiovascular diseases
    • 16091779 10.1139/y05-043 1:CAS:528:DC%2BD2MXhtFygsLzO
    • Bunnell BA, Deng W, Robinson CM et al (2005) Potential application for mesenchymal stem cells in the treatment of cardiovascular diseases. Can J Physiol Pharmacol 83:529-539
    • (2005) Can J Physiol Pharmacol , vol.83 , pp. 529-539
    • Bunnell, B.A.1    Deng, W.2    Robinson, C.M.3
  • 3
    • 33846432036 scopus 로고    scopus 로고
    • Cord-blood mesenchymal stem cells and tissue engineering
    • 17237555 10.1007/s12015-006-0023-x
    • Cetrulo CL Jr (2006) Cord-blood mesenchymal stem cells and tissue engineering. Stem Cell Rev 2:163-168
    • (2006) Stem Cell Rev , vol.2 , pp. 163-168
    • Cetrulo, Jr.C.L.1
  • 4
    • 27644565830 scopus 로고    scopus 로고
    • Chondrogenic potential of progenitor cells derived from human bone marrow and adipose tissue: A patient-matched comparison
    • 15936917 1:CAS:528:DC%2BD2MXhtFWht7rK
    • Huang JI, Kazmi N, Durbhakula MM, Hering TM, Yoo JU, Johnstone B (2005) Chondrogenic potential of progenitor cells derived from human bone marrow and adipose tissue: a patient-matched comparison. J Orthop Res 23:1383-1389
    • (2005) J Orthop Res , vol.23 , pp. 1383-1389
    • Huang, J.I.1    Kazmi, N.2    Durbhakula, M.M.3    Hering, T.M.4    Yoo, J.U.5    Johnstone, B.6
  • 5
    • 0043163695 scopus 로고    scopus 로고
    • Pluripotential of human adult stem cells and its application in reparative and reconstructive surgery
    • 12569806
    • Pan XH, Han YB, Guo KY (2002) Pluripotential of human adult stem cells and its application in reparative and reconstructive surgery. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 16:329-332
    • (2002) Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi , vol.16 , pp. 329-332
    • Pan, X.H.1    Han, Y.B.2    Guo, K.Y.3
  • 6
    • 37449032032 scopus 로고    scopus 로고
    • Pluripotency of embryonic stem cells
    • 18026755 10.1007/s00441-007-0520-5
    • Yamanaka S, Li J, Kania G et al (2008) Pluripotency of embryonic stem cells. Cell Tissue Res 331:5-22
    • (2008) Cell Tissue Res , vol.331 , pp. 5-22
    • Yamanaka, S.1    Li, J.2    Kania, G.3
  • 7
    • 0034712109 scopus 로고    scopus 로고
    • Out of eden: Stem cells and their niches
    • 10688781 10.1126/science.287.5457.1427 1:CAS:528:DC%2BD3cXhsV2qtro%3D
    • Watt FM, Hogan BL (2000) Out of eden: stem cells and their niches. Science 287:1427-1430
    • (2000) Science , vol.287 , pp. 1427-1430
    • Watt, F.M.1    Hogan, B.L.2
  • 9
    • 0035199276 scopus 로고    scopus 로고
    • Multilineage differentiation activity by cells isolated from umbilical cord blood: Expression of bone, fat, and neural markers
    • 11760145 10.1053/bbmt.2001.v7.pm11760145 1:STN:280: DC%2BD38%2FjsVylsw%3D%3D
    • Goodwin HS, Bicknese AR, Chien SN, Bogucki BD, Quinn CO, Wall DA (2001) Multilineage differentiation activity by cells isolated from umbilical cord blood: expression of bone, fat, and neural markers. Biol Blood Marrow Transplant 7:581-588
    • (2001) Biol Blood Marrow Transplant , vol.7 , pp. 581-588
    • Goodwin, H.S.1    Bicknese, A.R.2    Chien, S.N.3    Bogucki, B.D.4    Quinn, C.O.5    Wall, D.A.6
  • 10
    • 1442356953 scopus 로고    scopus 로고
    • Isolation of multipotent mesenchymal stem cells from umbilical cord blood
    • 14576065 10.1182/blood-2003-05-1670 1:CAS:528:DC%2BD2cXhvVOhsL4%3D
    • Lee OK, Kuo TK, Chen WM, Lee KD, Hsieh SL, Chen TH (2004) Isolation of multipotent mesenchymal stem cells from umbilical cord blood. Blood 103:1669-1675
    • (2004) Blood , vol.103 , pp. 1669-1675
    • Lee, O.K.1    Kuo, T.K.2    Chen, W.M.3    Lee, K.D.4    Hsieh, S.L.5    Chen, T.H.6
  • 11
    • 3242753546 scopus 로고    scopus 로고
    • Mesenchymal stem/progenitor cells in human umbilical cord blood as support for ex vivo expansion of cd34(+) hematopoietic stem cells and for chondrogenic differentiation
    • 15257936 1:CAS:528:DC%2BD2cXnsFSmsLY%3D
    • Wang JF, Wang LJ, Wu YF et al (2004) Mesenchymal stem/progenitor cells in human umbilical cord blood as support for ex vivo expansion of cd34(+) hematopoietic stem cells and for chondrogenic differentiation. Haematologica 89:837-844
    • (2004) Haematologica , vol.89 , pp. 837-844
    • Wang, J.F.1    Wang, L.J.2    Wu, Y.F.3
  • 12
    • 0035698442 scopus 로고    scopus 로고
    • Bmp-6 accelerates both chondrogenesis and mineral maturation in differentiating chick limb-bud mesenchymal cell cultures
    • 11813256 10.1002/jcb.10032 1:STN:280:DC%2BD387gt1amuw%3D%3D
    • Boskey AL, Paschalis EP, Binderman I, Doty SB (2002) Bmp-6 accelerates both chondrogenesis and mineral maturation in differentiating chick limb-bud mesenchymal cell cultures. J Cell Biochem 84:509-519
    • (2002) J Cell Biochem , vol.84 , pp. 509-519
    • Boskey, A.L.1    Paschalis, E.P.2    Binderman, I.3    Doty, S.B.4
  • 13
    • 0346120077 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 facilitates expression of chondrogenic, not osteogenic, phenotype of human intervertebral disc cells
    • 14673369 10.1097/01.BRS.0000101445.46487.16
    • Kim DJ, Moon SH, Kim H et al (2003) Bone morphogenetic protein-2 facilitates expression of chondrogenic, not osteogenic, phenotype of human intervertebral disc cells. Spine 28:2679-2684
    • (2003) Spine , vol.28 , pp. 2679-2684
    • Kim, D.J.1    Moon, S.H.2    Kim, H.3
  • 14
    • 33645337383 scopus 로고    scopus 로고
    • Effect of igf-i in the chondrogenesis of bone marrow mesenchymal stem cells in the presence or absence of tgf-beta signaling
    • 16598383 10.1359/jbmr.051213 1:CAS:528:DC%2BD28Xkt1Kqs7o%3D
    • Longobardi L, O'Rear L, Aakula S et al (2006) Effect of igf-i in the chondrogenesis of bone marrow mesenchymal stem cells in the presence or absence of tgf-beta signaling. J Bone Miner Res 21:626-636
    • (2006) J Bone Miner Res , vol.21 , pp. 626-636
    • Longobardi, L.1    O'Rear, L.2    Aakula, S.3
  • 15
    • 0037072760 scopus 로고    scopus 로고
    • Functions of transforming growth factor-beta family type i receptors and smad proteins in the hypertrophic maturation and osteoblastic differentiation of chondrocytes
    • 12082094 10.1074/jbc.M202086200 1:CAS:528:DC%2BD38Xnt1Skt7k%3D
    • Valcourt U, Gouttenoire J, Moustakas A, Herbage D, Mallein-Gerin F (2002) Functions of transforming growth factor-beta family type i receptors and smad proteins in the hypertrophic maturation and osteoblastic differentiation of chondrocytes. J Biol Chem 277:33545-33558
    • (2002) J Biol Chem , vol.277 , pp. 33545-33558
    • Valcourt, U.1    Gouttenoire, J.2    Moustakas, A.3    Herbage, D.4    Mallein-Gerin, F.5
  • 16
    • 85003186936 scopus 로고
    • Transforming growth factor-beta gene family members and bone
    • 8156937 1:CAS:528:DyaK2cXivFShsLw%3D
    • Centrella M, Horowitz MC, Wozney JM, McCarthy TL (1994) Transforming growth factor-beta gene family members and bone. Endocr Rev 15:27-39
    • (1994) Endocr Rev , vol.15 , pp. 27-39
    • Centrella, M.1    Horowitz, M.C.2    Wozney, J.M.3    McCarthy, T.L.4
  • 17
    • 0037261211 scopus 로고    scopus 로고
    • Combined effects of insulin-like growth factor-1 and transforming growth factor-beta1 on periosteal mesenchymal cells during chondrogenesis in vitro
    • 12505488 10.1053/joca.2002.0869 1:STN:280:DC%2BD38jkt1Chuw%3D%3D
    • Fukumoto T, Sperling JW, Sanyal A et al (2003) Combined effects of insulin-like growth factor-1 and transforming growth factor-beta1 on periosteal mesenchymal cells during chondrogenesis in vitro. Osteoarthr Cartil 11:55-64
    • (2003) Osteoarthr Cartil , vol.11 , pp. 55-64
    • Fukumoto, T.1    Sperling, J.W.2    Sanyal, A.3
  • 18
    • 0344011669 scopus 로고    scopus 로고
    • Bmp treatment of c3h10t1/2 mesenchymal stem cells induces both chondrogenesis and osteogenesis
    • 14635186 10.1002/jcb.10734 1:CAS:528:DC%2BD3sXpslSgs7c%3D
    • Shea CM, Edgar CM, Einhorn TA, Gerstenfeld LC (2003) Bmp treatment of c3h10t1/2 mesenchymal stem cells induces both chondrogenesis and osteogenesis. J Cell Biochem 90:1112-1127
    • (2003) J Cell Biochem , vol.90 , pp. 1112-1127
    • Shea, C.M.1    Edgar, C.M.2    Einhorn, T.A.3    Gerstenfeld, L.C.4
  • 19
    • 0024893773 scopus 로고
    • Bone morphogenetic proteins
    • 2491264 10.1016/0955-2235(89)90015-X 1:CAS:528:DyaK3cXhslGqtLk%3D
    • Wozney JM (1989) Bone morphogenetic proteins. Prog Growth Factor Res 1:267-280
    • (1989) Prog Growth Factor Res , vol.1 , pp. 267-280
    • Wozney, J.M.1
  • 20
    • 19144366775 scopus 로고    scopus 로고
    • Bmp-2 induces the expression of chondrocyte-specific genes in bovine synovium-derived progenitor cells cultured in three-dimensional alginate hydrogel
    • 15922187 10.1016/j.joca.2005.02.006 1:STN:280:DC%2BD2M3nvFKgsA%3D%3D
    • Park Y, Sugimoto M, Watrin A, Chiquet M, Hunziker EB (2005) Bmp-2 induces the expression of chondrocyte-specific genes in bovine synovium-derived progenitor cells cultured in three-dimensional alginate hydrogel. Osteoarthr Cartil 13:527-536
    • (2005) Osteoarthr Cartil , vol.13 , pp. 527-536
    • Park, Y.1    Sugimoto, M.2    Watrin, A.3    Chiquet, M.4    Hunziker, E.B.5
  • 21
    • 0025857671 scopus 로고
    • Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro
    • 1849907 10.1083/jcb.113.3.681 1:CAS:528:DyaK3MXitVSntbw%3D
    • Yamaguchi A, Katagiri T, Ikeda T et al (1991) Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro. J Cell Biol 113:681-687
    • (1991) J Cell Biol , vol.113 , pp. 681-687
    • Yamaguchi, A.1    Katagiri, T.2    Ikeda, T.3
  • 22
    • 23844505021 scopus 로고    scopus 로고
    • N-cadherin mediated distribution of beta-catenin alters map kinase and bmp-2 signaling on chondrogenesis-related gene expression
    • 15723280 10.1002/jcb.20396 1:CAS:528:DC%2BD2MXjvFeisrw%3D
    • Modarresi R, Lafond T, Roman-Blas JA, Danielson KG, Tuan RS, Seghatoleslami MR (2005) N-cadherin mediated distribution of beta-catenin alters map kinase and bmp-2 signaling on chondrogenesis-related gene expression. J Cell Biochem 95:53-63
    • (2005) J Cell Biochem , vol.95 , pp. 53-63
    • Modarresi, R.1    Lafond, T.2    Roman-Blas, J.A.3    Danielson, K.G.4    Tuan, R.S.5    Seghatoleslami, M.R.6
  • 23
    • 0033024513 scopus 로고    scopus 로고
    • Chondrogenic differentiation of murine c3h10t1/2 multipotential mesenchymal cells: Ii. Stimulation by bone morphogenetic protein-2 requires modulation of n-cadherin expression and function
    • 10234805 10.1046/j.1432-0436.1999.6420077.x 1:CAS:528:DyaK1MXhsl2hurc%3D
    • Haas AR, Tuan RS (1999) Chondrogenic differentiation of murine c3h10t1/2 multipotential mesenchymal cells: Ii. Stimulation by bone morphogenetic protein-2 requires modulation of n-cadherin expression and function. Differentiation 64:77-89
    • (1999) Differentiation , vol.64 , pp. 77-89
    • Haas, A.R.1    Tuan, R.S.2
  • 24
    • 0028639162 scopus 로고
    • Spatiotemporal profile of n-cadherin expression in the developing limb mesenchyme
    • 7743138 10.3109/15419069409014216 1:CAS:528:DyaK2MXkvVSmsbY%3D
    • Oberlender SA, Tuan RS (1994) Spatiotemporal profile of n-cadherin expression in the developing limb mesenchyme. Cell Adhes Commun 2:521-537
    • (1994) Cell Adhes Commun , vol.2 , pp. 521-537
    • Oberlender, S.A.1    Tuan, R.S.2
  • 25
    • 0028107165 scopus 로고
    • Expression and functional involvement of n-cadherin in embryonic limb chondrogenesis
    • 8119125 1:CAS:528:DyaK2cXjtF2ktrc%3D
    • Oberlender SA, Tuan RS (1994) Expression and functional involvement of n-cadherin in embryonic limb chondrogenesis. Development 120:177-187
    • (1994) Development , vol.120 , pp. 177-187
    • Oberlender, S.A.1    Tuan, R.S.2
  • 26
    • 38349150344 scopus 로고    scopus 로고
    • Characterization of mesenchymal stromal cells derived from full-term umbilical cord blood
    • 18202975 10.1080/14653240701732763 1:CAS:528:DC%2BD1cXnsFektQ%3D%3D
    • Manca MF, Zwart I, Beo J et al (2008) Characterization of mesenchymal stromal cells derived from full-term umbilical cord blood. Cytotherapy 10:54-68
    • (2008) Cytotherapy , vol.10 , pp. 54-68
    • Manca, M.F.1    Zwart, I.2    Beo, J.3
  • 27
    • 47749084684 scopus 로고    scopus 로고
    • Dissimilar differentiation of mesenchymal stem cells from bone marrow, umbilical cord blood, and adipose tissue
    • 10.3181/0712-RM-356 1:CAS:528:DC%2BD1cXotVygsro%3D
    • Rebelatto CK, Aguiar AM, Moretao MP et al (2008) Dissimilar differentiation of mesenchymal stem cells from bone marrow, umbilical cord blood, and adipose tissue. Exp Biol Med (Maywood) 233:901-913
    • (2008) Exp Biol Med (Maywood) , vol.233 , pp. 901-913
    • Rebelatto, C.K.1    Aguiar, A.M.2    Moretao, M.P.3
  • 28
    • 33746571978 scopus 로고    scopus 로고
    • Differentiating characterization of human umbilical cord blood-derived mesenchymal stem cells in vitro
    • 16716607 10.1016/j.cellbi.2006.02.007 1:CAS:528:DC%2BD28Xns12rtbo%3D
    • Kang XQ, Zang WJ, Bao LJ, Li DL, Xu XL, Yu XJ (2006) Differentiating characterization of human umbilical cord blood-derived mesenchymal stem cells in vitro. Cell Biol Int 30:569-575
    • (2006) Cell Biol Int , vol.30 , pp. 569-575
    • Kang, X.Q.1    Zang, W.J.2    Bao, L.J.3    Li, D.L.4    Xu, X.L.5    Yu, X.J.6
  • 29
    • 0034079140 scopus 로고    scopus 로고
    • Mesenchymal progenitor cells in human umbilical cord blood
    • 10848804 10.1046/j.1365-2141.2000.01986.x 1:STN:280: DC%2BD3czgvVSqtw%3D%3D
    • Erices A, Conget P, Minguell JJ (2000) Mesenchymal progenitor cells in human umbilical cord blood. Br J Haematol 109:235-242
    • (2000) Br J Haematol , vol.109 , pp. 235-242
    • Erices, A.1    Conget, P.2    Minguell, J.J.3
  • 30
    • 77954440153 scopus 로고    scopus 로고
    • Regulation of chondrogenesis by transforming growth factor-ss3 and insulin-like growth factor-1 from human mesenchymal umbilical cord blood cells
    • 20472924 10.3899/jrheum.091169 1:CAS:528:DC%2BC3cXhtVKlu7%2FP
    • Mara CS, Duarte AS, Sartori A, Luzo AC, Saad ST, Coimbra IB (2010) Regulation of chondrogenesis by transforming growth factor-ss3 and insulin-like growth factor-1 from human mesenchymal umbilical cord blood cells. J Rheumatol 37:1519-1526
    • (2010) J Rheumatol , vol.37 , pp. 1519-1526
    • Mara, C.S.1    Duarte, A.S.2    Sartori, A.3    Luzo, A.C.4    Saad, S.T.5    Coimbra, I.B.6
  • 31
    • 17344379375 scopus 로고    scopus 로고
    • Characterization of the adherent cells developed in dexter-type long-term cultures from human umbilical cord blood
    • 10661571 10.1634/stemcells.18-1-46 1:STN:280:DC%2BD3c7isFaisQ%3D%3D
    • Gutierrez-Rodriguez M, Reyes-Maldonado E, Mayani H (2000) Characterization of the adherent cells developed in dexter-type long-term cultures from human umbilical cord blood. Stem Cells 18:46-52
    • (2000) Stem Cells , vol.18 , pp. 46-52
    • Gutierrez-Rodriguez, M.1    Reyes-Maldonado, E.2    Mayani, H.3
  • 32
    • 0034766264 scopus 로고    scopus 로고
    • Isolation of human mesenchymal stem cells: Bone marrow versus umbilical cord blood
    • 11602418 1:STN:280:DC%2BD3MrlsFOgtA%3D%3D
    • Mareschi K, Biasin E, Piacibello W, Aglietta M, Madon E, Fagioli F (2001) Isolation of human mesenchymal stem cells: Bone marrow versus umbilical cord blood. Haematologica 86:1099-1100
    • (2001) Haematologica , vol.86 , pp. 1099-1100
    • Mareschi, K.1    Biasin, E.2    Piacibello, W.3    Aglietta, M.4    Madon, E.5    Fagioli, F.6
  • 33
    • 0037541500 scopus 로고    scopus 로고
    • Adult bone marrow is a rich source of human mesenchymal 'stem' cells but umbilical cord and mobilized adult blood are not
    • 12694261 10.1046/j.1365-2141.2003.04284.x
    • Wexler SA, Donaldson C, Denning-Kendall P, Rice C, Bradley B, Hows JM (2003) Adult bone marrow is a rich source of human mesenchymal 'stem' cells but umbilical cord and mobilized adult blood are not. Br J Haematol 121:368-374
    • (2003) Br J Haematol , vol.121 , pp. 368-374
    • Wexler, S.A.1    Donaldson, C.2    Denning-Kendall, P.3    Rice, C.4    Bradley, B.5    Hows, J.M.6
  • 34
    • 0034244385 scopus 로고    scopus 로고
    • Biology and clinical utilization of mesenchymal progenitor cells
    • 10920429 10.1590/S0100-879X2000000800003 1:STN:280:DC%2BD3cvntVSiug%3D%3D
    • Minguell JJ, Conget P, Erices A (2000) Biology and clinical utilization of mesenchymal progenitor cells. Braz J Med Biol Res 33:881-887
    • (2000) Braz J Med Biol Res , vol.33 , pp. 881-887
    • Minguell, J.J.1    Conget, P.2    Erices, A.3
  • 35
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • 10102814 10.1126/science.284.5411.143 1:CAS:528:DyaK1MXitlCnu7o%3D
    • Pittenger MF, Mackay AM, Beck SC et al (1999) Multilineage potential of adult human mesenchymal stem cells. Science 284:143-147
    • (1999) Science , vol.284 , pp. 143-147
    • Pittenger, M.F.1    MacKay, A.M.2    Beck, S.C.3
  • 36
    • 34547162587 scopus 로고    scopus 로고
    • Concise review: No breakthroughs for human mesenchymal and embryonic stem cell culture: Conditioned medium, feeder layer, or feeder-free; Medium with fetal calf serum, human serum, or enriched plasma; Serum-free, serum replacement nonconditioned medium, or ad hoc formula? All that glitters is not gold!
    • 17395775 10.1634/stemcells.2007-0127 1:CAS:528:DC%2BD2sXos12hsL0%3D
    • Mannello F, Tonti GA (2007) Concise review: no breakthroughs for human mesenchymal and embryonic stem cell culture: conditioned medium, feeder layer, or feeder-free; medium with fetal calf serum, human serum, or enriched plasma; serum-free, serum replacement nonconditioned medium, or ad hoc formula? All that glitters is not gold! Stem Cells 25:1603-1609
    • (2007) Stem Cells , vol.25 , pp. 1603-1609
    • Mannello, F.1    Tonti, G.A.2
  • 37
    • 3543031635 scopus 로고    scopus 로고
    • Chondrogenic differentiation of mesenchymal stem cells and its clinical applications
    • 15250049
    • Lee JW, Kim YH, Kim SH, Han SH, Hahn SB (2004) Chondrogenic differentiation of mesenchymal stem cells and its clinical applications. Yonsei Med J 45(Suppl):41-47
    • (2004) Yonsei Med J , vol.45 , Issue.SUPPL. , pp. 41-47
    • Lee, J.W.1    Kim, Y.H.2    Kim, S.H.3    Han, S.H.4    Hahn, S.B.5
  • 38
    • 0036299082 scopus 로고    scopus 로고
    • P38 map kinase regulation of ap-2 binding in tgf-beta1-stimulated chondrogenesis of human trabecular bone-derived cells
    • 12081893 10.1111/j.1749-6632.2002.tb03077.x 1:CAS:528: DC%2BD38XlvVOisbg%3D
    • Tuli R, Seghatoleslami MR, Tuli S, Howard MS, Danielson KG, Tuan RS (2002) P38 map kinase regulation of ap-2 binding in tgf-beta1-stimulated chondrogenesis of human trabecular bone-derived cells. Ann N Y Acad Sci 961:172-177
    • (2002) Ann N y Acad Sci , vol.961 , pp. 172-177
    • Tuli, R.1    Seghatoleslami, M.R.2    Tuli, S.3    Howard, M.S.4    Danielson, K.G.5    Tuan, R.S.6
  • 39
    • 0033051415 scopus 로고    scopus 로고
    • High density micromass cultures of embryonic limb bud mesenchymal cells: An in vitro model of endochondral skeletal development
    • 10475272 10.1007/s11626-999-0070-0 1:STN:280:DyaK1Mvgt1amtQ%3D%3D
    • Mello MA, Tuan RS (1999) High density micromass cultures of embryonic limb bud mesenchymal cells: an in vitro model of endochondral skeletal development. In Vitro Cell Dev Biol Anim 35:262-269
    • (1999) Vitro Cell Dev Biol Anim , vol.35 , pp. 262-269
    • Mello, M.A.1    Tuan, R.S.2
  • 40
    • 0142103359 scopus 로고    scopus 로고
    • Transforming growth factor-beta-mediated chondrogenesis of human mesenchymal progenitor cells involves n-cadherin and mitogen-activated protein kinase and wnt signaling cross-talk
    • 12893825 10.1074/jbc.M305312200 1:CAS:528:DC%2BD3sXotFWgur8%3D
    • Tuli R, Tuli S, Nandi S et al (2003) Transforming growth factor-beta-mediated chondrogenesis of human mesenchymal progenitor cells involves n-cadherin and mitogen-activated protein kinase and wnt signaling cross-talk. J Biol Chem 278:41227-41236
    • (2003) J Biol Chem , vol.278 , pp. 41227-41236
    • Tuli, R.1    Tuli, S.2    Nandi, S.3
  • 41
    • 55449106914 scopus 로고    scopus 로고
    • Chondrogenic differentiation capacity of human mesenchymal progenitor cells derived from subchondral cortico-spongious bone
    • 18464264 10.1002/jor.20635 1:CAS:528:DC%2BD1cXhtlaitrzF
    • Neumann K, Dehne T, Endres M et al (2008) Chondrogenic differentiation capacity of human mesenchymal progenitor cells derived from subchondral cortico-spongious bone. J Orthop Res 26:1449-1456
    • (2008) J Orthop Res , vol.26 , pp. 1449-1456
    • Neumann, K.1    Dehne, T.2    Endres, M.3
  • 42
    • 0034989585 scopus 로고    scopus 로고
    • Efficient chondrogenic differentiation of mesenchymal cells in micromass culture by retroviral gene transfer of bmp-2
    • 11683496 10.1046/j.1432-0436.2001.670405.x 1:CAS:528:DC%2BD3MXmtVylsb0%3D
    • Carlberg AL, Pucci B, Rallapalli R, Tuan RS, Hall DJ (2001) Efficient chondrogenic differentiation of mesenchymal cells in micromass culture by retroviral gene transfer of bmp-2. Differentiation 67:128-138
    • (2001) Differentiation , vol.67 , pp. 128-138
    • Carlberg, A.L.1    Pucci, B.2    Rallapalli, R.3    Tuan, R.S.4    Hall, D.J.5
  • 43
    • 49649109581 scopus 로고    scopus 로고
    • Sox9, a key transcription factor of bone morphogenetic protein-2-induced chondrogenesis, is activated through bmp pathway and a ccaat box in the proximal promoter
    • 18506848 10.1002/jcp.21496 1:CAS:528:DC%2BD1cXhtVyrsrvE
    • Pan Q, Yu Y, Chen Q et al (2008) Sox9, a key transcription factor of bone morphogenetic protein-2-induced chondrogenesis, is activated through bmp pathway and a ccaat box in the proximal promoter. J Cell Physiol 217:228-241
    • (2008) J Cell Physiol , vol.217 , pp. 228-241
    • Pan, Q.1    Yu, Y.2    Chen, Q.3
  • 44
    • 0027965225 scopus 로고
    • Recombinant vgr-1/bmp-6-expressing tumors induce fibrosis and endochondral bone formation in vivo
    • 8089189 10.1083/jcb.126.6.1595 1:CAS:528:DyaK2cXlt1Kjs74%3D
    • Gitelman SE, Kobrin MS, Ye JQ, Lopez AR, Lee A, Derynck R (1994) Recombinant vgr-1/bmp-6-expressing tumors induce fibrosis and endochondral bone formation in vivo. J Cell Biol 126:1595-1609
    • (1994) J Cell Biol , vol.126 , pp. 1595-1609
    • Gitelman, S.E.1    Kobrin, M.S.2    Ye, J.Q.3    Lopez, A.R.4    Lee, A.5    Derynck, R.6
  • 45
    • 0033034858 scopus 로고    scopus 로고
    • Bmp-6 is an autocrine stimulator of chondrocyte differentiation
    • 10234567 10.1359/jbmr.1999.14.4.475 1:CAS:528:DyaK1MXitlOrsr4%3D
    • Grimsrud CD, Romano PR, D'Souza M et al (1999) Bmp-6 is an autocrine stimulator of chondrocyte differentiation. J Bone Miner Res 14:475-482
    • (1999) J Bone Miner Res , vol.14 , pp. 475-482
    • Grimsrud, C.D.1    Romano, P.R.2    D'Souza, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.