-
1
-
-
0023472191
-
Clinical pharmacology of recombinant human tumor necrosis factor in patients with advanced cancer
-
Chapman P B, Lester T J, Casper E S, et al. Clinical pharmacology of recombinant human tumor necrosis factor in patients with advanced cancer. J Clin Oncol, 1987, 5: 1942-1951.
-
(1987)
J Clin Oncol
, vol.5
, pp. 1942-1951
-
-
Chapman, P.B.1
Lester, T.J.2
Casper, E.S.3
-
2
-
-
0035291191
-
SMANCS and polymer-conjugated macromolecular drugs: advantages in cancer chemotherapy
-
Maeda H. SMANCS and polymer-conjugated macromolecular drugs: advantages in cancer chemotherapy. Adv Drug Deliver Rev, 2001, 46: 169-185.
-
(2001)
Adv Drug Deliver Rev
, vol.46
, pp. 169-185
-
-
Maeda, H.1
-
3
-
-
0023178374
-
Phase I study of recombinant tumor necrosis factor in cancer patients
-
Blick M, Sherwin S A, Rosenblum M, et al. Phase I study of recombinant tumor necrosis factor in cancer patients. Cancer Res, 1987, 47: 2986-2989.
-
(1987)
Cancer Res
, vol.47
, pp. 2986-2989
-
-
Blick, M.1
Sherwin, S.A.2
Rosenblum, M.3
-
4
-
-
0037362655
-
Effect of PEGylation on pharmaceuticals
-
Harris J M, Chess R B. Effect of PEGylation on pharmaceuticals. Nat Rev Drug Discov, 2003, 2: 214-221.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 214-221
-
-
Harris, J.M.1
Chess, R.B.2
-
5
-
-
0029058648
-
Molecular design of hybrid tumour necrosis factor alpha with polyethylene glycol increases its anti-tumour potency
-
Tsutsumi Y, Kihira T, Tsunoda S, et al. Molecular design of hybrid tumour necrosis factor alpha with polyethylene glycol increases its anti-tumour potency. Br J Cancer, 1995, 71: 963-968.
-
(1995)
Br J Cancer
, vol.71
, pp. 963-968
-
-
Tsutsumi, Y.1
Kihira, T.2
Tsunoda, S.3
-
6
-
-
0028047803
-
Chemical modification of natural human tumor necrosis factor-alpha with polyethylene glycol increases its anti-tumor potency
-
Tsutsumi Y, Kihira T, Yamamoto S, et al. Chemical modification of natural human tumor necrosis factor-alpha with polyethylene glycol increases its anti-tumor potency. Jpn J Cancer Res, 1994, 85: 9-12.
-
(1994)
Jpn J Cancer Res
, vol.85
, pp. 9-12
-
-
Tsutsumi, Y.1
Kihira, T.2
Yamamoto, S.3
-
7
-
-
0029786093
-
Molecular design of hybrid tumour necrosis factor-alpha. II: The molecular size of polyethylene glycol-modified tumour necrosis factor-alpha affects its anti-tumour potency
-
Tsutsumi Y, Tsunoda S, Kamada H, et al. Molecular design of hybrid tumour necrosis factor-alpha. II: The molecular size of polyethylene glycol-modified tumour necrosis factor-alpha affects its anti-tumour potency. Br J Cancer, 1996, 74: 1090-1095.
-
(1996)
Br J Cancer
, vol.74
, pp. 1090-1095
-
-
Tsutsumi, Y.1
Tsunoda, S.2
Kamada, H.3
-
8
-
-
18244377180
-
Structural and biologic characterization of PEGylated recombinant IFN-alpha2b
-
Grace M, Youngster S, Gitlin G, et al. Structural and biologic characterization of PEGylated recombinant IFN-alpha2b. J Interferon Cytokine Res, 2001, 21: 1103-1115.
-
(2001)
J Interferon Cytokine Res
, vol.21
, pp. 1103-1115
-
-
Grace, M.1
Youngster, S.2
Gitlin, G.3
-
9
-
-
33748689917
-
GlycoPEGylation of recombinant therapeutic proteins produced in Escherichia coli
-
DeFrees S, Wang Z G, Xing R, et al. GlycoPEGylation of recombinant therapeutic proteins produced in Escherichia coli. Glycobiology, 2006, 16: 833-843.
-
(2006)
Glycobiology
, vol.16
, pp. 833-843
-
-
DeFrees, S.1
Wang, Z.G.2
Xing, R.3
-
10
-
-
33646863688
-
Site-specific PEGylation of native disulfide bonds in therapeutic proteins
-
Shaunak S, Godwin A, Choi J W, et al. Site-specific PEGylation of native disulfide bonds in therapeutic proteins. Nat Chem Biol, 2006, 2: 312-313.
-
(2006)
Nat Chem Biol
, vol.2
, pp. 312-313
-
-
Shaunak, S.1
Godwin, A.2
Choi, J.W.3
-
11
-
-
36549050782
-
Releasable PEGylation of proteins with customized linkers
-
Filpula D, Zhao H. Releasable PEGylation of proteins with customized linkers. Adv Drug Deliv Rev, 2008, 60: 29-49.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 29-49
-
-
Filpula, D.1
Zhao, H.2
-
12
-
-
0343433408
-
Cysteine proteases and their inhibitors
-
Otto H H, Schirmeister T. Cysteine proteases and their inhibitors. Chem Rev, 1997, 97: 133-172.
-
(1997)
Chem Rev
, vol.97
, pp. 133-172
-
-
Otto, H.H.1
Schirmeister, T.2
-
13
-
-
0034805342
-
Significance of cathepsin B accumulation in synovial fluid of rheumatoid arthritis
-
Hashimoto Y, Kakegawa H, Narita Y, et al. Significance of cathepsin B accumulation in synovial fluid of rheumatoid arthritis. Biochem Bioph Res Commun, 2001, 283: 334-339.
-
(2001)
Biochem Bioph Res Commun
, vol.283
, pp. 334-339
-
-
Hashimoto, Y.1
Kakegawa, H.2
Narita, Y.3
-
14
-
-
0019948262
-
L-trans-epoxysuccinyl-leucylamido (4-guanidino) butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L
-
Barrett A J, Kembhavi A A, Brown M A, et al. L-trans-epoxysuccinyl-leucylamido (4-guanidino) butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L. Biochem J, 1982, 201: 189-198.
-
(1982)
Biochem J
, vol.201
, pp. 189-198
-
-
Barrett, A.J.1
Kembhavi, A.A.2
Brown, M.A.3
-
15
-
-
0036009640
-
Star structure of antibody-targeted HPMA copolymer-bound doxorubicin: a novel type of polymeric conjugate for targeted drug delivery with potent antitumor effect
-
Kovar M, Strohalm J, Etrych T, et al. Star structure of antibody-targeted HPMA copolymer-bound doxorubicin: a novel type of polymeric conjugate for targeted drug delivery with potent antitumor effect. Bioconjug Chem, 2002, 13: 206-215.
-
(2002)
Bioconjug Chem
, vol.13
, pp. 206-215
-
-
Kovar, M.1
Strohalm, J.2
Etrych, T.3
-
16
-
-
0026926542
-
Influence of a peptide linker on biodistribution and metabolism of antibody-conjugated benzyl-EDTA. Comparison of enzymic digestion in vitro and in vivo
-
Studer M, Kroger L A, DeNardo S J, et al. Influence of a peptide linker on biodistribution and metabolism of antibody-conjugated benzyl-EDTA. Comparison of enzymic digestion in vitro and in vivo. Bioconjug Chem, 1992, 3: 424-429.
-
(1992)
Bioconjug Chem
, vol.3
, pp. 424-429
-
-
Studer, M.1
Kroger, L.A.2
DeNardo, S.J.3
-
17
-
-
0031925731
-
Synthesis of a lipophilic daunoruhicin derivative and its incorporation into lipidic carriers developed for LDL receptor-mediated tumor therapy
-
Versluis A J, Rump E T, Rensen P C N, et al. Synthesis of a lipophilic daunoruhicin derivative and its incorporation into lipidic carriers developed for LDL receptor-mediated tumor therapy. Pharm Res, 1998, 15: 531-537.
-
(1998)
Pharm Res
, vol.15
, pp. 531-537
-
-
Versluis, A.J.1
Rump, E.T.2
Rensen, P.C.N.3
-
18
-
-
4444297534
-
Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer
-
Afar D E H, Bhaskar V, Ibsen E, et al. Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer. Mol Cancer Ther, 2004, 3: 921-932.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 921-932
-
-
Afar, D.E.H.1
Bhaskar, V.2
Ibsen, E.3
-
19
-
-
0042738861
-
cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity
-
Francisco J A, Cerveny C G, Meyer D L, et al. cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity. Blood, 2003, 102: 1458-1465.
-
(2003)
Blood
, vol.102
, pp. 1458-1465
-
-
Francisco, J.A.1
Cerveny, C.G.2
Meyer, D.L.3
-
20
-
-
12244295755
-
In vivo Drug-linker stability of an anti-CD30 dipeptide-linked auristatin immunoconjugate
-
Sanderson R J, Hering M A, James S F, et al. In vivo Drug-linker stability of an anti-CD30 dipeptide-linked auristatin immunoconjugate. Clin Cancer Res, 2005, 11: 843-852.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 843-852
-
-
Sanderson, R.J.1
Hering, M.A.2
James, S.F.3
-
21
-
-
79951559228
-
Linkage with cathepsin B-sensitive dipeptide promotes the in vitro and in vivo anticancer activity of PEGylated tumor necrosis factor-alpha (TNF-α) against murine fibrosarcoma
-
Dai C Y, Fu Y, Li B, et al. Linkage with cathepsin B-sensitive dipeptide promotes the in vitro and in vivo anticancer activity of PEGylated tumor necrosis factor-alpha (TNF-α) against murine fibrosarcoma. Sci China Life Sci, 2011, 54: 128-138.
-
(2011)
Sci China Life Sci
, vol.54
, pp. 128-138
-
-
Dai, C.Y.1
Fu, Y.2
Li, B.3
-
22
-
-
0022704801
-
A fluorometric assay of the degree of modification of protein primary amines with polyethylene glycol
-
Stocks S J, Jones A J M, Ramey C W, et al. A fluorometric assay of the degree of modification of protein primary amines with polyethylene glycol. Anal Biochem, 1986, 154: 232-234.
-
(1986)
Anal Biochem
, vol.154
, pp. 232-234
-
-
Stocks, S.J.1
Jones, A.J.M.2
Ramey, C.W.3
-
23
-
-
0022996348
-
Proposal of standardized methods and reference for assaying recombinant human tumor necrosis factor
-
Yamazaki S, Onishi E, Enami K, et al. Proposal of standardized methods and reference for assaying recombinant human tumor necrosis factor. Jpn J Med Sci Biol, 1986, 39: 105-118.
-
(1986)
Jpn J Med Sci Biol
, vol.39
, pp. 105-118
-
-
Yamazaki, S.1
Onishi, E.2
Enami, K.3
-
24
-
-
0033551121
-
Molecular design of conjugated tumor necrosis factor-alpha: synthesis and characteristics of polyvinyl pyrrolidone modified tumor necrosis factor-alpha
-
Kamada H, Tsutsumi Y, Tsunoda S, et al. Molecular design of conjugated tumor necrosis factor-alpha: synthesis and characteristics of polyvinyl pyrrolidone modified tumor necrosis factor-alpha. Biochem Biophys Res Commun, 1999, 257: 448-453.
-
(1999)
Biochem Biophys Res Commun
, vol.257
, pp. 448-453
-
-
Kamada, H.1
Tsutsumi, Y.2
Tsunoda, S.3
-
25
-
-
0029803056
-
A combined assay of cell viability and in vitro cytotoxicity with a highly water-soluble tetrazolium salt, neutral red and crystal violet
-
Ishiyama M, Tominaga H, Shiga M, et al. A combined assay of cell viability and in vitro cytotoxicity with a highly water-soluble tetrazolium salt, neutral red and crystal violet. Biol Pharm Bull 1996, 19: 1518-1520.
-
(1996)
Biol Pharm Bull
, vol.19
, pp. 1518-1520
-
-
Ishiyama, M.1
Tominaga, H.2
Shiga, M.3
-
26
-
-
0021203525
-
Antitumor activity of murine tumor necrosis factor (TNF) against transplanted murine tumors and heterotransplanted human tumors in nude mice
-
Haranaka K, Satomi N, Sakurai A. Antitumor activity of murine tumor necrosis factor (TNF) against transplanted murine tumors and heterotransplanted human tumors in nude mice. Int J Cancer, 1984, 34: 263-267.
-
(1984)
Int J Cancer
, vol.34
, pp. 263-267
-
-
Haranaka, K.1
Satomi, N.2
Sakurai, A.3
-
27
-
-
0016723594
-
An endotoxin-induced serum factor that causes necrosis of tumors
-
Carswell E A, Old L J, Kassel R L, et al. An endotoxin-induced serum factor that causes necrosis of tumors. Proc Natl Acad Sci USA, 1975, 72: 3666-3670.
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, pp. 3666-3670
-
-
Carswell, E.A.1
Old, L.J.2
Kassel, R.L.3
-
28
-
-
0027280820
-
Uptake and degradation of glyceraldehyde-3-phosphate dehydrogenase by rat liver lysosomes
-
Aniento F, Roche E, Cuervo A M, et al. Uptake and degradation of glyceraldehyde-3-phosphate dehydrogenase by rat liver lysosomes. J Biol Chem, 1993, 268: 10463-10470.
-
(1993)
J Biol Chem
, vol.268
, pp. 10463-10470
-
-
Aniento, F.1
Roche, E.2
Cuervo, A.M.3
-
29
-
-
0026101682
-
Novel epoxysuccinyl peptides. Selective inhibitors of cathepsin B, in vitro
-
Murata M, Miyashita S, Yokoo C, et al. Novel epoxysuccinyl peptides. Selective inhibitors of cathepsin B, in vitro. FEBS Lett, 1991, 280: 307-310.
-
(1991)
FEBS Lett
, vol.280
, pp. 307-310
-
-
Murata, M.1
Miyashita, S.2
Yokoo, C.3
-
31
-
-
0032959549
-
Phase I clinical and pharmacokinetic study of PK1 [N-(2-hydroxypropyl)methacrylamide copolymer doxorubicin]: first member of a new class of chemotherapeutic agents-drug-polymer conjugates
-
Vasey P A, Kaye S B, Morrison R, et al. Phase I clinical and pharmacokinetic study of PK1 [N-(2-hydroxypropyl)methacrylamide copolymer doxorubicin]: first member of a new class of chemotherapeutic agents-drug-polymer conjugates. Clin Cancer Res, 1999, 5: 83-94.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 83-94
-
-
Vasey, P.A.1
Kaye, S.B.2
Morrison, R.3
|